DK1976886T3 - Means and methods for the treatment of tumor diseases - Google Patents
Means and methods for the treatment of tumor diseases Download PDFInfo
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- DK1976886T3 DK1976886T3 DK06818912T DK06818912T DK1976886T3 DK 1976886 T3 DK1976886 T3 DK 1976886T3 DK 06818912 T DK06818912 T DK 06818912T DK 06818912 T DK06818912 T DK 06818912T DK 1976886 T3 DK1976886 T3 DK 1976886T3
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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Landscapes
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| WO2006114115A1 (de) | 2005-04-26 | 2006-11-02 | Trion Pharma Gmbh | Kombination von antikörpern mit glukokortikoiden zur behandlung von krebs |
| PT1976886E (pt) * | 2005-12-16 | 2015-03-09 | Amgen Res Munich Gmbh | Meios e processos para o tratamento de doenças tumorais |
| ES2402591T3 (es) | 2006-08-14 | 2013-05-07 | Xencor Inc. | Anticuerpos optimizados que seleccionan como diana CD19 |
| HUE028175T2 (en) | 2008-11-07 | 2016-12-28 | Amgen Res Munich Gmbh | Treatment of acute lymphoblastic leukemia |
| RS53980B1 (sr) | 2008-11-07 | 2015-10-30 | Amgen Research (Munich) Gmbh | Tretiranje akutne limfoblastne leukemije kod dece |
| US8840888B2 (en) * | 2009-10-27 | 2014-09-23 | Micromet Ag | Dosage regimen for administering a CD19XCD3 bispecific antibody |
| US8658765B2 (en) | 2009-12-31 | 2014-02-25 | Avidbiotics Corp. | Non-natural MIC proteins |
| US8796420B2 (en) | 2009-12-31 | 2014-08-05 | Avidbiotics Corp. | Non-natural MIC proteins |
| HUE048639T2 (hu) * | 2010-10-27 | 2020-08-28 | Amgen Res Munich Gmbh | Eljárás DLBCL kezelésére |
| EP3228315B1 (en) | 2010-11-10 | 2020-11-25 | Amgen Research (Munich) GmbH | Prevention of adverse effects caused by cd3 specific binding domains |
| US9249217B2 (en) | 2010-12-03 | 2016-02-02 | Secretary, DHHS | Bispecific EGFRvIII x CD3 antibody engaging molecules |
| CA2832360C (en) | 2011-04-28 | 2022-05-03 | Amgen Research (Munich) Gmbh | Dosage regimen for administering a cd19xcd3 bispecific antibody to patients at risk for potential adverse effects |
| US20140004121A1 (en) | 2012-06-27 | 2014-01-02 | Amgen Inc. | Anti-mesothelin binding proteins |
| US9486475B2 (en) | 2013-02-08 | 2016-11-08 | Amgen Research (Munich) Gmbh | PPS for the prevention of potential adverse effects caused by CD3 specific binding domains |
| JO3529B1 (ar) | 2013-02-08 | 2020-07-05 | Amgen Res Munich Gmbh | مضاد التصاق خلايا الدم البيض من أجل التخفيف من الاثار السلبية الممكنة الناتجة عن مجالات ارتباط cd3- المحدد |
| ES2960807T3 (es) | 2013-10-11 | 2024-03-06 | Us Health | Anticuerpos contra TEM8 y su uso |
| WO2015103549A1 (en) | 2014-01-03 | 2015-07-09 | The United States Of America, As Represented By The Secretary Department Of Health And Human Services | Neutralizing antibodies to hiv-1 env and their use |
| LT3149480T (lt) | 2014-05-30 | 2019-04-25 | Amgen Research (Munich) Gmbh | B ląstelių pirmtakų ūmia limfoblastine leukemija (all) sergančių pacientų rizikos stratifikacijos būdas |
| EP3218397B8 (en) | 2014-11-14 | 2021-04-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Neutralizing antibodies to ebola virus glycoprotein and their use |
| PT3560953T (pt) * | 2014-12-24 | 2024-03-26 | Autolus Ltd | Célula |
| US10563194B2 (en) | 2015-02-24 | 2020-02-18 | BioAlta, LLC | Conditionally active biological proteins |
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| EP3271389B8 (en) | 2015-03-20 | 2020-04-22 | The United States of America, as represented by the Secretary, Department of Health and Human Services | Neutralizing antibodies to gp120 and their use |
| IL319047A (en) | 2015-08-28 | 2025-04-01 | Amunix Operating Inc | Chimeric polypeptide composition and methods for its preparation and use |
| WO2017062748A1 (en) | 2015-10-07 | 2017-04-13 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Il-7r-alpha specific antibodies for treating acute lymphoblastic leukemia |
| AU2016349392B2 (en) | 2015-11-03 | 2023-07-13 | The Trustees Of Columbia University In The City Of New York | Neutralizing antibodies to HIV-1 gp41 and their use |
| WO2017192589A1 (en) | 2016-05-02 | 2017-11-09 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Neutralizing antibodies to influenza ha and their use and identification |
| CA3029426A1 (en) | 2016-06-30 | 2018-01-04 | Oncorus, Inc. | Pseudotyped oncolytic viral delivery of therapeutic polypeptides |
| JP2020506971A (ja) | 2017-02-08 | 2020-03-05 | ドラゴンフライ セラピューティクス, インコーポレイテッド | ナチュラルキラー細胞の活性化のための多重特異性結合タンパク質およびがんを処置するためのその治療的使用 |
| WO2018148660A1 (en) | 2017-02-10 | 2018-08-16 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Neutralizing antibodies to plasmodium falciparum circumsporozoite protein and their use |
| SG11201907646YA (en) | 2017-02-20 | 2019-09-27 | Dragonfly Therapeutics Inc | Proteins binding her2, nkg2d and cd16 |
| JP2021508477A (ja) * | 2017-12-29 | 2021-03-11 | オンコラス, インコーポレイテッド | 治療用ポリペプチドの腫瘍溶解性ウイルス送達 |
| WO2019136029A1 (en) | 2018-01-02 | 2019-07-11 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Neutralizing antibodies to ebola virus glycoprotein and their use |
| PE20210375A1 (es) | 2018-02-08 | 2021-03-02 | Dragonfly Therapeutics Inc | Terapia de combinacion del cancer que incluye proteinas de union multiespecificas que activan a las celulas asesinas naturales |
| FI3749346T3 (fi) | 2018-02-08 | 2024-09-04 | Dragonfly Therapeutics Inc | Nkg2d-reseptoriin kohdistuvat vasta-aineen vaihtelevan domeenin yhdistelmät |
| MX2020008684A (es) | 2018-02-20 | 2020-12-07 | Dragonfly Therapeutics Inc | Proteinas de union multiespecificas que se unen a cd33, nkg2d y cd16 y metodos de uso. |
| CA3091437A1 (en) | 2018-02-21 | 2019-08-29 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Neutralizing antibodies to hiv-1 env and their use |
| JP7482363B2 (ja) | 2018-08-08 | 2024-05-14 | ドラゴンフライ セラピューティクス, インコーポレイテッド | Nkg2d、cd16及び腫瘍関連抗原に結合するタンパク質 |
| US12384851B2 (en) | 2018-08-08 | 2025-08-12 | Dragonfly Therapeutics, Inc. | Multi-specific binding proteins that bind BCMA, NKG2D and CD16, and methods of use |
| EA202091888A1 (ru) | 2018-08-08 | 2020-10-23 | Драгонфлай Терапьютикс, Инк. | Вариабельные домены антител, нацеленные на рецептор nkg2d |
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| DE19725586C2 (de) * | 1997-06-17 | 1999-06-24 | Gsf Forschungszentrum Umwelt | Verfahren zur Herstellung von Zellpräparaten zur Immunisierung mittels heterologer intakter bispezifischer und/oder trispezifischer Antikörper |
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| US8076459B2 (en) * | 2003-10-16 | 2011-12-13 | Micromet Ag | Multispecfic deimmunized CD3-binders |
| WO2006114115A1 (de) | 2005-04-26 | 2006-11-02 | Trion Pharma Gmbh | Kombination von antikörpern mit glukokortikoiden zur behandlung von krebs |
| PT1976886E (pt) * | 2005-12-16 | 2015-03-09 | Amgen Res Munich Gmbh | Meios e processos para o tratamento de doenças tumorais |
| HUE028175T2 (en) * | 2008-11-07 | 2016-12-28 | Amgen Res Munich Gmbh | Treatment of acute lymphoblastic leukemia |
| WO2021057978A1 (zh) * | 2019-09-27 | 2021-04-01 | 南京金斯瑞生物科技有限公司 | 抗vhh域抗体及其用途 |
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2006
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- 2006-11-29 RU RU2008129080/13A patent/RU2008129080A/ru not_active Application Discontinuation
- 2006-11-29 PL PL06818912T patent/PL1976886T3/pl unknown
- 2006-11-29 HR HRP20150175TT patent/HRP20150175T1/hr unknown
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- 2006-11-29 SI SI200631893T patent/SI1976886T1/sl unknown
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- 2006-11-29 JP JP2008544796A patent/JP5442998B2/ja active Active
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- 2006-11-29 EP EP06818912.5A patent/EP1976886B1/en active Active
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2011
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2021
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Also Published As
| Publication number | Publication date |
|---|---|
| US20220088196A1 (en) | 2022-03-24 |
| PL1976886T3 (pl) | 2015-06-30 |
| HRP20150175T1 (en) | 2015-03-27 |
| US20090291072A1 (en) | 2009-11-26 |
| CA2633594A1 (en) | 2007-06-21 |
| JP5834056B2 (ja) | 2015-12-16 |
| AU2006326727A1 (en) | 2007-06-21 |
| SI1976886T1 (sl) | 2015-03-31 |
| RU2008129080A (ru) | 2010-01-27 |
| ES2532124T3 (es) | 2015-03-24 |
| CY1116041T1 (el) | 2017-01-25 |
| HK1116202A1 (en) | 2008-12-19 |
| EP1976886A1 (en) | 2008-10-08 |
| WO2007068354A1 (en) | 2007-06-21 |
| US20130095103A1 (en) | 2013-04-18 |
| CA2633594C (en) | 2021-10-26 |
| PT1976886E (pt) | 2015-03-09 |
| RS53905B1 (sr) | 2015-08-31 |
| JP2009519257A (ja) | 2009-05-14 |
| US8007796B2 (en) | 2011-08-30 |
| EP1976886B1 (en) | 2014-12-17 |
| JP5442998B2 (ja) | 2014-03-19 |
| JP2014028840A (ja) | 2014-02-13 |
| US11154617B2 (en) | 2021-10-26 |
| WO2007068354A8 (en) | 2007-08-09 |
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