DK1976886T3 - Means and methods for the treatment of tumor diseases - Google Patents

Means and methods for the treatment of tumor diseases Download PDF

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Publication number
DK1976886T3
DK1976886T3 DK06818912T DK06818912T DK1976886T3 DK 1976886 T3 DK1976886 T3 DK 1976886T3 DK 06818912 T DK06818912 T DK 06818912T DK 06818912 T DK06818912 T DK 06818912T DK 1976886 T3 DK1976886 T3 DK 1976886T3
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Denmark
Prior art keywords
use according
ser
bispecific
single chain
chain antibody
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DK06818912T
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Danish (da)
English (en)
Inventor
Patrick Baeuerle
Peter Kufer
Matthias Klinger
Eugen Leo
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Amgen Res Munich Gmbh
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Publication of DK1976886T3 publication Critical patent/DK1976886T3/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK06818912T 2005-12-16 2006-11-29 Means and methods for the treatment of tumor diseases DK1976886T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05027606 2005-12-16
EP06004144 2006-03-01
PCT/EP2006/011466 WO2007068354A1 (en) 2005-12-16 2006-11-29 Means and methods for the treatment of tumorous diseases

Publications (1)

Publication Number Publication Date
DK1976886T3 true DK1976886T3 (en) 2015-03-02

Family

ID=37944802

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06818912T DK1976886T3 (en) 2005-12-16 2006-11-29 Means and methods for the treatment of tumor diseases

Country Status (15)

Country Link
US (3) US8007796B2 (enExample)
EP (1) EP1976886B1 (enExample)
JP (2) JP5442998B2 (enExample)
AU (1) AU2006326727A1 (enExample)
CA (1) CA2633594C (enExample)
CY (1) CY1116041T1 (enExample)
DK (1) DK1976886T3 (enExample)
ES (1) ES2532124T3 (enExample)
HR (1) HRP20150175T1 (enExample)
PL (1) PL1976886T3 (enExample)
PT (1) PT1976886E (enExample)
RS (1) RS53905B1 (enExample)
RU (1) RU2008129080A (enExample)
SI (1) SI1976886T1 (enExample)
WO (1) WO2007068354A1 (enExample)

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Also Published As

Publication number Publication date
US20220088196A1 (en) 2022-03-24
PL1976886T3 (pl) 2015-06-30
HRP20150175T1 (en) 2015-03-27
US20090291072A1 (en) 2009-11-26
CA2633594A1 (en) 2007-06-21
JP5834056B2 (ja) 2015-12-16
AU2006326727A1 (en) 2007-06-21
SI1976886T1 (sl) 2015-03-31
RU2008129080A (ru) 2010-01-27
ES2532124T3 (es) 2015-03-24
CY1116041T1 (el) 2017-01-25
HK1116202A1 (en) 2008-12-19
EP1976886A1 (en) 2008-10-08
WO2007068354A1 (en) 2007-06-21
US20130095103A1 (en) 2013-04-18
CA2633594C (en) 2021-10-26
PT1976886E (pt) 2015-03-09
RS53905B1 (sr) 2015-08-31
JP2009519257A (ja) 2009-05-14
US8007796B2 (en) 2011-08-30
EP1976886B1 (en) 2014-12-17
JP5442998B2 (ja) 2014-03-19
JP2014028840A (ja) 2014-02-13
US11154617B2 (en) 2021-10-26
WO2007068354A8 (en) 2007-08-09

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