DK1933869T3 - Anvendelse af IL-23- og IL-17-antagonister til behandling af autoimmun øjenbetændelsessygdom - Google Patents
Anvendelse af IL-23- og IL-17-antagonister til behandling af autoimmun øjenbetændelsessygdomInfo
- Publication number
- DK1933869T3 DK1933869T3 DK06813945.0T DK06813945T DK1933869T3 DK 1933869 T3 DK1933869 T3 DK 1933869T3 DK 06813945 T DK06813945 T DK 06813945T DK 1933869 T3 DK1933869 T3 DK 1933869T3
- Authority
- DK
- Denmark
- Prior art keywords
- inflammatory disease
- antagonists
- treatment
- eye inflammatory
- autoimmune eye
- Prior art date
Links
- 230000001363 autoimmune Effects 0.000 title abstract 2
- 208000027866 inflammatory disease Diseases 0.000 title abstract 2
- 239000005557 antagonist Substances 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229940126534 drug product Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Pulmonology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71379205P | 2005-09-01 | 2005-09-01 | |
| US83731206P | 2006-08-11 | 2006-08-11 | |
| PCT/US2006/033840 WO2007027761A2 (en) | 2005-09-01 | 2006-08-30 | Use of il-23 and il-17 antagonists to treat autoimmune ocular inflammatory disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1933869T3 true DK1933869T3 (da) | 2010-03-01 |
Family
ID=37686002
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK06813945.0T DK1933869T3 (da) | 2005-09-01 | 2006-08-30 | Anvendelse af IL-23- og IL-17-antagonister til behandling af autoimmun øjenbetændelsessygdom |
Country Status (21)
| Country | Link |
|---|---|
| US (6) | US20080199460A1 (enExample) |
| EP (3) | EP2116258A1 (enExample) |
| JP (3) | JP2009507023A (enExample) |
| CN (1) | CN101296706B (enExample) |
| AT (1) | ATE445415T1 (enExample) |
| AU (1) | AU2006284841B2 (enExample) |
| BR (1) | BRPI0615297A2 (enExample) |
| CA (1) | CA2621086A1 (enExample) |
| CY (1) | CY1110606T1 (enExample) |
| DE (1) | DE602006009834D1 (enExample) |
| DK (1) | DK1933869T3 (enExample) |
| ES (1) | ES2333260T3 (enExample) |
| HR (1) | HRP20100014T1 (enExample) |
| NO (1) | NO20081574L (enExample) |
| NZ (2) | NZ566424A (enExample) |
| PL (1) | PL1933869T3 (enExample) |
| PT (1) | PT1933869E (enExample) |
| RS (1) | RS51142B (enExample) |
| SI (1) | SI1933869T1 (enExample) |
| TW (2) | TWI372061B (enExample) |
| WO (1) | WO2007027761A2 (enExample) |
Families Citing this family (80)
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| GB0417487D0 (en) | 2004-08-05 | 2004-09-08 | Novartis Ag | Organic compound |
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| AU2007260787A1 (en) | 2006-06-13 | 2007-12-21 | Zymogenetics, Inc | IL-17 and IL-23 antagonists and methods of using the same |
| US7833527B2 (en) | 2006-10-02 | 2010-11-16 | Amgen Inc. | Methods of treating psoriasis using IL-17 Receptor A antibodies |
| NZ579297A (en) * | 2007-02-28 | 2012-03-30 | Schering Corp | Combination therapy comprising an il-23 antagonist and a cytokine antagonist for treatment of immune disorders |
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| EP2174667B1 (en) * | 2007-07-26 | 2017-01-04 | Osaka University | Agent for treatment of ophthalmia containing interleukin-6 receptor inhibitor as active ingredient |
| US20110212100A1 (en) * | 2007-08-15 | 2011-09-01 | Tracy Keller | Methods for modulating development and expansion of il-17 expressing cells |
| EP2215125A1 (en) | 2007-11-27 | 2010-08-11 | Ablynx N.V. | Method for obtaining polypeptide constructs comprising two or more single domain antibodies |
| WO2009082624A2 (en) * | 2007-12-10 | 2009-07-02 | Zymogenetics, Inc. | Antagonists of il-17a, il-17f, and il-23 and methods of using the same |
| EP2242504B1 (en) * | 2008-01-09 | 2021-07-14 | The Schepens Eye Research Institute, Inc. | Therapeutic compositions for treatment of ocular inflammatory disorders |
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| WO2010081091A2 (en) * | 2009-01-09 | 2010-07-15 | Schepens Eye Research Institute | Therapeutic compositions for treatment of corneal disorders |
| US20120014970A1 (en) * | 2009-01-09 | 2012-01-19 | Reza Dana | Therapeutic Compositions for Treatment of Corneal Disorders |
| SG174891A1 (en) * | 2009-04-01 | 2011-11-28 | Genentech Inc | Treatment of insulin-resistant disorders |
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| WO2011033493A1 (en) | 2009-09-21 | 2011-03-24 | Conservatoire National des Arts et Métiers | Carrier conjugates of il-23-peptides and their induced antibodies |
| EA201891433A3 (ru) | 2010-01-15 | 2019-02-28 | Кирин-Эмджен, Инк. | Состав антитела и терапевтические режимы |
| US20110311527A1 (en) | 2010-06-16 | 2011-12-22 | Allergan, Inc. | IL23p19 ANTIBODY INHIBITOR FOR TREATING OCULAR AND OTHER CONDITIONS |
| US8853150B2 (en) | 2010-07-29 | 2014-10-07 | Eleven Biotherapeutics, Inc. | Chimeric IL-1 receptor type I antagonists |
| WO2012045848A1 (en) * | 2010-10-08 | 2012-04-12 | Novartis Ag | Methods of treating psoriasis using il-17 antagonists |
| PT2635601T (pt) | 2010-11-04 | 2016-09-27 | Boehringer Ingelheim Int | Anticorpos anti-il-23 |
| GB201112091D0 (en) | 2011-07-14 | 2011-08-31 | Gt Biolog Ltd | Bacterial strains isolated from pigs |
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| WO2013059644A1 (en) * | 2011-10-21 | 2013-04-25 | Baylor College Of Medicine | Method to measure inflammation in the conjunctiva of patients with tear dysfunction |
| US9284283B2 (en) | 2012-02-02 | 2016-03-15 | Ensemble Therapeutics Corporation | Macrocyclic compounds for modulating IL-17 |
| EP2834273B1 (en) | 2012-04-05 | 2018-08-22 | F.Hoffmann-La Roche Ag | Bispecific antibodies against human tweak and human il17 and uses thereof |
| EP4039275A1 (en) | 2012-05-03 | 2022-08-10 | Boehringer Ingelheim International GmbH | Anti-il-23p19 antibodies |
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| US10507241B2 (en) | 2014-07-24 | 2019-12-17 | Boehringer Ingelheim International Gmbh | Biomarkers useful in the treatment of IL-23A related diseases |
| EA039598B9 (ru) | 2014-09-03 | 2022-03-10 | Бёрингер Ингельхайм Интернациональ Гмбх | Соединение, нацеленное на ил-23а и фно-альфа, и его применение |
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| MA55434B1 (fr) | 2015-06-15 | 2022-02-28 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| PT3240554T (pt) | 2015-06-15 | 2019-11-04 | 4D Pharma Res Ltd | Blautia stercosis e wexlerae para uso no tratamento de doenças inflamatórias e autoimunes |
| MA41060B1 (fr) | 2015-06-15 | 2019-11-29 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| PT3307288T (pt) | 2015-06-15 | 2019-10-17 | 4D Pharma Res Ltd | Composições compreendendo estirpes bacterianas |
| HK1258292A1 (zh) * | 2015-09-17 | 2019-11-08 | Amgen Inc. | 使用il23途徑生物標誌物預測il23拮抗劑的臨床應答 |
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| GB201520497D0 (en) | 2015-11-20 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| GB201520631D0 (en) * | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| GB201520638D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| GB201612191D0 (en) | 2016-07-13 | 2016-08-24 | 4D Pharma Plc | Compositions comprising bacterial strains |
| AU2017226831B2 (en) | 2016-03-04 | 2018-10-04 | 4D Pharma Plc | Compositions comprising bacterial Blautia strains for treating visceral hypersensitivity |
| TW201821093A (zh) | 2016-07-13 | 2018-06-16 | 英商4D製藥有限公司 | 包含細菌菌株之組合物 |
| GB201621123D0 (en) | 2016-12-12 | 2017-01-25 | 4D Pharma Plc | Compositions comprising bacterial strains |
| HUE054164T2 (hu) | 2017-05-22 | 2021-08-30 | 4D Pharma Res Ltd | Baktériumtörzseket tartalmazó készítmények |
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| US12286482B2 (en) | 2020-08-05 | 2025-04-29 | Synthekine, Inc. | IL10RB binding molecules and encoding nucleic acids |
| WO2022031884A2 (en) | 2020-08-05 | 2022-02-10 | Synthekine, Inc. | Il2rg binding molecules and methods of use |
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| TW200815469A (en) * | 2006-06-23 | 2008-04-01 | Astrazeneca Ab | Compounds |
-
2006
- 2006-08-30 WO PCT/US2006/033840 patent/WO2007027761A2/en not_active Ceased
- 2006-08-30 BR BRPI0615297-0A patent/BRPI0615297A2/pt not_active IP Right Cessation
- 2006-08-30 AT AT06813945T patent/ATE445415T1/de active
- 2006-08-30 EP EP09164605A patent/EP2116258A1/en not_active Withdrawn
- 2006-08-30 EP EP06813945A patent/EP1933869B1/en not_active Revoked
- 2006-08-30 HR HR20100014T patent/HRP20100014T1/hr unknown
- 2006-08-30 US US11/512,622 patent/US20080199460A1/en not_active Abandoned
- 2006-08-30 DE DE602006009834T patent/DE602006009834D1/de active Active
- 2006-08-30 PL PL06813945T patent/PL1933869T3/pl unknown
- 2006-08-30 ES ES06813945T patent/ES2333260T3/es active Active
- 2006-08-30 EP EP10180648.7A patent/EP2322219A3/en not_active Withdrawn
- 2006-08-30 AU AU2006284841A patent/AU2006284841B2/en not_active Ceased
- 2006-08-30 CN CN2006800403078A patent/CN101296706B/zh not_active Expired - Fee Related
- 2006-08-30 PT PT06813945T patent/PT1933869E/pt unknown
- 2006-08-30 NZ NZ566424A patent/NZ566424A/en not_active IP Right Cessation
- 2006-08-30 CA CA002621086A patent/CA2621086A1/en not_active Abandoned
- 2006-08-30 NZ NZ595262A patent/NZ595262A/xx not_active IP Right Cessation
- 2006-08-30 DK DK06813945.0T patent/DK1933869T3/da active
- 2006-08-30 JP JP2008529228A patent/JP2009507023A/ja not_active Withdrawn
- 2006-08-30 RS RSP-2009/0529A patent/RS51142B/sr unknown
- 2006-08-30 SI SI200630517T patent/SI1933869T1/sl unknown
- 2006-08-31 TW TW095132202A patent/TWI372061B/zh not_active IP Right Cessation
- 2006-08-31 TW TW101115664A patent/TWI463993B/zh not_active IP Right Cessation
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2008
- 2008-03-31 NO NO20081574A patent/NO20081574L/no not_active Application Discontinuation
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2009
- 2009-12-21 US US12/643,166 patent/US20100111954A1/en not_active Abandoned
- 2009-12-21 US US12/643,152 patent/US8524230B2/en not_active Expired - Fee Related
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2010
- 2010-01-12 CY CY20101100034T patent/CY1110606T1/el unknown
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2011
- 2011-01-28 US US13/015,900 patent/US20110142831A1/en not_active Abandoned
- 2011-06-28 JP JP2011143593A patent/JP5462838B2/ja not_active Expired - Fee Related
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2013
- 2013-08-06 US US13/960,441 patent/US20130323251A1/en not_active Abandoned
- 2013-08-13 JP JP2013168006A patent/JP2014005285A/ja active Pending
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2014
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