DK1928892T3 - Glycomimetiske inhibitorer af PA-IL-lectin PA-IIL-lectin eller begge lectiner fra pseudomonas - Google Patents

Glycomimetiske inhibitorer af PA-IL-lectin PA-IIL-lectin eller begge lectiner fra pseudomonas

Info

Publication number
DK1928892T3
DK1928892T3 DK06801019.8T DK06801019T DK1928892T3 DK 1928892 T3 DK1928892 T3 DK 1928892T3 DK 06801019 T DK06801019 T DK 06801019T DK 1928892 T3 DK1928892 T3 DK 1928892T3
Authority
DK
Denmark
Prior art keywords
lectin
pseudomonas
bacteria
lectins
iil
Prior art date
Application number
DK06801019.8T
Other languages
Danish (da)
English (en)
Inventor
John L Magnani
John T Patton Jr
Arun K Sarkar
Original Assignee
Glycomimetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glycomimetics Inc filed Critical Glycomimetics Inc
Application granted granted Critical
Publication of DK1928892T3 publication Critical patent/DK1928892T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/21—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Pseudomonadaceae (F)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
DK06801019.8T 2005-08-09 2006-08-08 Glycomimetiske inhibitorer af PA-IL-lectin PA-IIL-lectin eller begge lectiner fra pseudomonas DK1928892T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70654605P 2005-08-09 2005-08-09
US81019006P 2006-06-01 2006-06-01
PCT/US2006/030993 WO2007021721A2 (en) 2005-08-09 2006-08-08 Glycomimetic inhibitors of the pa-il lectin, pa-iil lectin or both the lectins from pseudomonas

Publications (1)

Publication Number Publication Date
DK1928892T3 true DK1928892T3 (da) 2012-01-30

Family

ID=37600887

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06801019.8T DK1928892T3 (da) 2005-08-09 2006-08-08 Glycomimetiske inhibitorer af PA-IL-lectin PA-IIL-lectin eller begge lectiner fra pseudomonas

Country Status (10)

Country Link
US (3) US7517980B2 (https=)
EP (1) EP1928892B1 (https=)
JP (2) JP5175190B2 (https=)
CN (1) CN101291946B (https=)
AT (1) ATE528311T1 (https=)
AU (1) AU2006280101B2 (https=)
CA (1) CA2618638C (https=)
DK (1) DK1928892T3 (https=)
ES (1) ES2375979T3 (https=)
WO (1) WO2007021721A2 (https=)

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PT2794626T (pt) 2011-12-22 2018-01-12 Glycomimetics Inc Compostos de antagonistas de e-selectina
EP2650289B1 (en) * 2012-04-10 2016-07-27 Universität Konstanz Glycomimetics as pseudomonas Aeruginosa lectin inhibitors
CA2891514C (en) 2012-12-07 2020-08-25 Glycomimetics, Inc. Compounds, compositions and methods using e-selectin antagonists for mobilization of hematopoietic cells
US9328370B2 (en) * 2013-05-15 2016-05-03 Simpson Biotech Co., Ltd. Recombinant bacteria recognizing protein and uses thereof
KR101492720B1 (ko) * 2013-05-23 2015-02-12 경상대학교산학협력단 2-브로모알칸산을 유효성분으로 포함하는 항생제 조성물
CN103342725B (zh) * 2013-07-26 2016-09-14 济南尚博生物科技有限公司 一种β端基硫代糖苷化合物的分离提纯方法
CN105017341B (zh) * 2014-04-22 2018-05-15 华东师范大学 硫酸化岩藻-半乳四糖及其制备方法和应用
ES2754549T3 (es) 2014-12-03 2020-04-20 Glycomimetics Inc Inhibidores heterobifuncionales de E-selectinas y receptores de quimioquinas CXCR4
JP2019502727A (ja) * 2016-01-22 2019-01-31 グリコミメティクス， インコーポレイテッド Ｐａ−ｉｌおよび／またはｐａ−ｉｉｌレクチンの糖模倣体阻害剤
WO2017151708A1 (en) 2016-03-02 2017-09-08 Glycomimetics, Inc. Methods for the treatment and/or prevention of cardiovescular disease by inhibition of e-selectin
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US11072625B2 (en) 2016-10-07 2021-07-27 Glycomimetics, Inc. Highly potent multimeric e-selectin antagonists
CA3054605A1 (en) 2017-03-15 2018-09-20 Glycomimetics, Inc. Galactopyranosyl-cyclohexyl derivatives as e-selectin antagonists
WO2019108750A1 (en) 2017-11-30 2019-06-06 Glycomimetics, Inc. Methods of mobilizing marrow infiltrating lymphocytes and uses thereof
CN111566117A (zh) 2017-12-29 2020-08-21 糖模拟物有限公司 E-选择蛋白和半乳凝素-3的异双功能抑制剂
WO2019173229A1 (en) 2018-03-05 2019-09-12 Glycomimetics, Inc. Methods for treating acute myeloid leukemia and related conditions
CN118373810A (zh) 2018-12-27 2024-07-23 糖模拟物有限公司 抑制c-糖苷的半乳凝素-3
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3

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JP2013049718A (ja) 2013-03-14
US8258290B2 (en) 2012-09-04
JP5175190B2 (ja) 2013-04-03
ES2375979T3 (es) 2012-03-07
CA2618638A1 (en) 2007-02-22
WO2007021721A2 (en) 2007-02-22
ATE528311T1 (de) 2011-10-15
US7517980B2 (en) 2009-04-14
EP1928892A2 (en) 2008-06-11
WO2007021721A3 (en) 2007-04-26
US20100041626A1 (en) 2010-02-18
AU2006280101A1 (en) 2007-02-22
CA2618638C (en) 2014-03-11
EP1928892B1 (en) 2011-10-12
CN101291946B (zh) 2011-06-29
JP2009504660A (ja) 2009-02-05
AU2006280101B2 (en) 2012-06-28
US20070037775A1 (en) 2007-02-15
US20120329755A1 (en) 2012-12-27

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