DK190776A - Fremgangsmade til rensning af hepatitis b antigen - Google Patents

Fremgangsmade til rensning af hepatitis b antigen

Info

Publication number
DK190776A
DK190776A DK190776A DK190776A DK190776A DK 190776 A DK190776 A DK 190776A DK 190776 A DK190776 A DK 190776A DK 190776 A DK190776 A DK 190776A DK 190776 A DK190776 A DK 190776A
Authority
DK
Denmark
Prior art keywords
hepatitis
antigen
procedures
cleaning
Prior art date
Application number
DK190776A
Other languages
English (en)
Other versions
DK145347C (da
DK145347B (da
Inventor
A U Bertland
A A Tytell
G P Lampson
E B Buynak
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK190776A publication Critical patent/DK190776A/da
Publication of DK145347B publication Critical patent/DK145347B/da
Application granted granted Critical
Publication of DK145347C publication Critical patent/DK145347C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK190776A 1975-05-14 1976-04-28 Fremgangsmaade til rensning af hepatitis b antigen DK145347C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/577,483 US4017360A (en) 1975-05-14 1975-05-14 Method for purifying hepatitis B antigen
US57748375 1975-05-14

Publications (3)

Publication Number Publication Date
DK190776A true DK190776A (da) 1976-11-15
DK145347B DK145347B (da) 1982-11-01
DK145347C DK145347C (da) 1983-05-02

Family

ID=24308922

Family Applications (1)

Application Number Title Priority Date Filing Date
DK190776A DK145347C (da) 1975-05-14 1976-04-28 Fremgangsmaade til rensning af hepatitis b antigen

Country Status (15)

Country Link
US (1) US4017360A (da)
JP (2) JPS51139619A (da)
AU (1) AU504454B2 (da)
BE (1) BE841811A (da)
CA (1) CA1066191A (da)
CH (1) CH629668A5 (da)
CY (1) CY1034A (da)
DE (1) DE2621276A1 (da)
DK (1) DK145347C (da)
ES (1) ES447858A1 (da)
FR (1) FR2315947A1 (da)
GB (1) GB1488774A (da)
HK (1) HK86779A (da)
NL (1) NL188621C (da)
SE (1) SE431161B (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE437329B (sv) * 1975-03-14 1985-02-25 Community Blood Council Sett att ur blodserum framstella vaccin mot virushepatit
US4129646A (en) * 1976-11-02 1978-12-12 Merck & Co., Inc. Isolating hepatitis B Dane particles
GB1554811A (en) * 1977-02-23 1979-10-31 Merck & Co Inc Purifying hepatitis b surface antigen
US4217418A (en) * 1978-05-08 1980-08-12 Merck & Co., Inc. Recovery of small particles by flow centrifugation
ATE1882T1 (de) * 1978-05-08 1982-12-15 Merck & Co. Inc. Ein verfahren zur direkten extraktion von kleinen teilchen bis 50 nm aus einer proteinhaltigen fluessigkeit.
ZA792485B (en) * 1978-06-07 1980-06-25 New York Blood Center Inc Vaccine for active immunization containing hepatitis b surface and/or e-antigens
US4181713A (en) * 1978-10-30 1980-01-01 Merck & Co., Inc. Isolation of HBs Ag
US4395395A (en) * 1979-05-21 1983-07-26 The United States Of America As Represented By The Department Of Health And Human Services Detection of non-A, non-B hepatitis associated antigen
DE2935634C2 (de) * 1979-09-04 1981-12-10 Battelle-Institut E.V., 6000 Frankfurt Tiermodell zur Prüfung der Inaktivierung von Impfstoffen gegen Virushepatitis Typ B und zur Prüfung von Chemotherapeutika gegen Virushepatitis Typ A
FR2470795A1 (fr) * 1979-12-07 1981-06-12 Pasteur Institut Procede de purification de particules d'origine biologique, notamment de l'antigene de surface du virus de l'hepatite b (aghbs) et les produits obtenus
US4349539A (en) * 1980-08-15 1982-09-14 Merck & Co., Inc. Separation of hepatitis B surface antigen
PL133476B1 (en) * 1981-06-10 1985-06-29 Akad Medyczna Method of obtaining pure antigen hba from human serum
AU8746582A (en) * 1981-09-02 1983-03-10 Biogen N.V. Hepatitis b virus e type antigen
GB8321789D0 (en) * 1983-08-12 1983-09-14 Biogen Nv Vaccines and compositions against hepatitis
US4639371A (en) * 1984-10-02 1987-01-27 New York Blood Center, Inc. Hepatitis B antigenic compositions and vaccines against hepatitis B derived therefrom
JPS61158798A (ja) * 1984-12-28 1986-07-18 Japan Found Cancer Res B型肝炎ウイルス表面抗原の製造法
US5026828A (en) * 1987-02-27 1991-06-25 Merck & Co., Inc. Method of purifying recombinant pres-1/S-2/S/S hepatitis B antigen from yeast
JPS63246335A (ja) * 1987-09-17 1988-10-13 メルク エンド カムパニー インコーポレーテツド 肝炎b抗原
US5030720A (en) * 1988-09-01 1991-07-09 Merck & Co., Inc. Pres2+S hepatitis B vaccine derived from plasma

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3636191A (en) * 1969-10-08 1972-01-18 Cancer Res Inst Vaccine against viral hepatitis and process
JPS5523254B2 (da) * 1974-01-28 1980-06-21

Also Published As

Publication number Publication date
SE7604818L (sv) 1976-11-15
DE2621276C2 (da) 1988-05-11
HK86779A (en) 1979-12-28
BE841811A (fr) 1976-11-16
NL7604429A (nl) 1976-11-16
DK145347C (da) 1983-05-02
JPS6345645B2 (da) 1988-09-12
CY1034A (en) 1980-08-01
US4017360A (en) 1977-04-12
AU1361976A (en) 1977-11-10
DE2621276A1 (de) 1976-11-25
CA1066191A (en) 1979-11-13
GB1488774A (en) 1977-10-12
AU504454B2 (en) 1979-10-18
JPS51139619A (en) 1976-12-02
CH629668A5 (de) 1982-05-14
NL188621B (nl) 1992-03-16
DK145347B (da) 1982-11-01
JPS58180432A (ja) 1983-10-21
JPS6112894B2 (da) 1986-04-10
NL188621C (nl) 1992-08-17
ES447858A1 (es) 1977-07-16
FR2315947A1 (fr) 1977-01-28
FR2315947B1 (da) 1979-03-30
SE431161B (sv) 1984-01-23

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