DK184783A - Hidtil ukendte derivater af aren og heteroaren carboxamider og deres anvendelse som laegemidler - Google Patents

Hidtil ukendte derivater af aren og heteroaren carboxamider og deres anvendelse som laegemidler Download PDF

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Publication number
DK184783A
DK184783A DK184783A DK184783A DK184783A DK 184783 A DK184783 A DK 184783A DK 184783 A DK184783 A DK 184783A DK 184783 A DK184783 A DK 184783A DK 184783 A DK184783 A DK 184783A
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DK
Denmark
Prior art keywords
aren
carboxamides
hetero
medicines
unknown derivatives
Prior art date
Application number
DK184783A
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English (en)
Other versions
DK184783D0 (da
Inventor
Marie-Christine Dubroeucq
Christian Renault
Gerard Le Fur
Original Assignee
Pharmuka Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmuka Lab filed Critical Pharmuka Lab
Publication of DK184783D0 publication Critical patent/DK184783D0/da
Publication of DK184783A publication Critical patent/DK184783A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Description

svovlatom eller gruppen ^N-R^, hvor repræsenter et hydrogenatom eller en alkylgruppe. og R£ kan sammen med nitrogenatomet, hvortil de er bundet, danne en heterocyklisk ring. Ar repræsenter en phenyl, pyridyl eller thienylgruppe eller en substitueret phenylgruppe, A og B repræsenter u-afhængigt af hinanden N eller CH-, og C repræsenter en benzen eller thiophen rest.
Disse forbindelser kan anvendes som lægemidler, især til benzodiazepiners forskellige anvendelser.
DK184783A 1982-04-27 1983-04-26 Hidtil ukendte derivater af aren og heteroaren carboxamider og deres anvendelse som laegemidler DK184783A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8207217 1982-04-27
FR8207217A FR2525595A1 (fr) 1982-04-27 1982-04-27 Nouveaux derives d'arene et d'heteroarenecarboxamides et leur utilisation comme medicaments

Publications (2)

Publication Number Publication Date
DK184783D0 DK184783D0 (da) 1983-04-26
DK184783A true DK184783A (da) 1983-10-28

Family

ID=9273433

Family Applications (1)

Application Number Title Priority Date Filing Date
DK184783A DK184783A (da) 1982-04-27 1983-04-26 Hidtil ukendte derivater af aren og heteroaren carboxamider og deres anvendelse som laegemidler

Country Status (16)

Country Link
US (1) US4499094A (da)
EP (1) EP0094271B1 (da)
JP (1) JPS58201756A (da)
AU (1) AU555417B2 (da)
CA (1) CA1207324A (da)
DE (1) DE3365086D1 (da)
DK (1) DK184783A (da)
ES (1) ES8406419A1 (da)
FR (1) FR2525595A1 (da)
GR (1) GR77909B (da)
HU (1) HU189271B (da)
IL (1) IL68326A0 (da)
MA (1) MA19777A1 (da)
NO (1) NO831466L (da)
PT (1) PT76528B (da)
ZA (1) ZA832925B (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2538388B1 (fr) * 1982-12-24 1985-06-21 Pharmuka Lab Nouveaux derives de naphtalene- ou azanaphtalenecarboxamide, leurs procedes de preparation et leur utilisation comme medicaments
US4649146A (en) * 1983-01-31 1987-03-10 Fujisawa Pharmaceutical Co., Ltd. Thiazole derivatives and pharmaceutical composition comprising the same
FR2582514B1 (fr) * 1985-05-30 1988-02-19 Rhone Poulenc Sante Medicaments a base d'amides, nouveaux amides et leur preparation
HU196758B (en) * 1986-05-21 1989-01-30 Gyogyszerkutato Intezet Process for production of 3-hidroxi-methil-quinolines and medical compositions containing them
EP0285671B1 (en) * 1986-10-13 2003-09-03 Asahi Kasei Kabushiki Kaisha Pyridine derivatives
DE3919348A1 (de) * 1988-06-16 1989-12-21 Ciba Geigy Ag Mikrobizide mittel
US5219864A (en) * 1991-03-12 1993-06-15 Kyowa Hakko Kogyo Co., Ltd. Thienopyridine derivatives
US5550124A (en) * 1991-12-10 1996-08-27 University Of Southern California Use of peripheral-type benzodiazpine sites for treatment of CNS trauma or disease
IL117659A (en) * 1995-04-13 2000-12-06 Dainippon Pharmaceutical Co Substituted 2-phenyl pyrimidino amino acetamide derivative process for preparing the same and a pharmaceutical composition containing same
WO1998014213A1 (fr) 1996-10-01 1998-04-09 Daiichi Pharmaceutical Co., Ltd. Stabilisateur de la membrane mitochondriale
CA2285402A1 (en) * 1997-04-25 1998-11-05 Kohei Notoya Amide derivatives, their production and use
AU7474998A (en) * 1997-05-07 1998-11-27 Emory University Haloisoquinoline carboxamide
ZA9810490B (en) 1997-12-03 1999-05-20 Dainippon Pharmaceutical Co 2-Aryl-8-oxodihydropurine derivative process for the preparation thereof pharmaceutical composition containing the same and intermediate therefor
FR2778564B1 (fr) * 1998-05-13 2001-07-13 Sanofi Sa Utilisation de composes reduisant l'apoptose
WO1999058117A1 (fr) * 1998-05-13 1999-11-18 Sanofi-Synthelabo Utilisation de composes reduisant l'apoptose
ES2246588T3 (es) * 1998-12-18 2006-02-16 Scios Inc. Tratamiento de enfermedades que implican formacion de quistes.
GB0516723D0 (en) * 2005-08-15 2005-09-21 Novartis Ag Organic compounds
CA2661307C (en) 2006-08-22 2016-07-19 Technion Research And Development Foundation Ltd. Heterocyclic derivatives binding to the peripheral-type benzodiazepine receptor (pbr)
WO2008063625A2 (en) * 2006-11-20 2008-05-29 Adolor Corporation Pyridine compounds and methods of their use
JP5441060B2 (ja) * 2007-10-31 2014-03-12 独立行政法人理化学研究所 創薬のためのｐｅｔスクリーニング用分子プローブを製造するためのキット
GB0907284D0 (en) 2009-04-28 2009-06-10 Queen Mary & Westfield College Compounds for inducing cellular apoptosis
WO2014164678A1 (en) * 2013-03-12 2014-10-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Translocator protein imaging agents; methods of manufacture, and methods of use thereof
US10035780B2 (en) 2014-04-23 2018-07-31 Technion Research & Development Foundation Ltd. Quinazoline scaffold based compounds, pharmaceutical compositions and methods of use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1069296A (en) * 1912-07-31 1913-08-05 Hoechst Ag Derivatives of phenylcinchoninic acid.
BE764299A (en) * 1971-03-12 1971-08-16 Malesci Sas Antifibrillatory ethylenediamines or imida- - zolines
FR2417512A1 (fr) * 1978-02-17 1979-09-14 Parcor Thieno (3,2-c) et thieno (2,3-c) pyridines, leur procede de preparation et leur application en therapeutique
FR2485014A1 (fr) * 1980-06-20 1981-12-24 Pharmindustrie Nouveaux derives de (quinolyl-2, -3 ou -4)-1 (piperidyl ou pyrrolidinyl-2 ou -3)-2 ou -3 ethanone ou propanone, procedes pour leur preparation, et leur utilisation comme medicaments

Also Published As

Publication number Publication date
AU1400283A (en) 1983-11-03
GR77909B (da) 1984-09-25
FR2525595B1 (da) 1985-03-22
ZA832925B (en) 1984-01-25
EP0094271B1 (fr) 1986-08-06
ES521864A0 (es) 1984-08-01
PT76528A (fr) 1983-05-01
HU189271B (en) 1986-06-30
CA1207324A (fr) 1986-07-08
FR2525595A1 (fr) 1983-10-28
EP0094271A2 (fr) 1983-11-16
AU555417B2 (en) 1986-09-25
DE3365086D1 (en) 1986-09-11
ES8406419A1 (es) 1984-08-01
JPS58201756A (ja) 1983-11-24
JPH0324467B2 (da) 1991-04-03
US4499094A (en) 1985-02-12
PT76528B (fr) 1985-12-09
MA19777A1 (fr) 1983-12-31
IL68326A0 (en) 1983-07-31
DK184783D0 (da) 1983-04-26
NO831466L (no) 1983-10-28
EP0094271A3 (en) 1984-07-04

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AHB Application shelved due to non-payment