BE764299A - Antifibrillatory ethylenediamines or imida- - zolines - Google Patents

Antifibrillatory ethylenediamines or imida- - zolines

Info

Publication number
BE764299A
BE764299A BE764299A BE764299A BE764299A BE 764299 A BE764299 A BE 764299A BE 764299 A BE764299 A BE 764299A BE 764299 A BE764299 A BE 764299A BE 764299 A BE764299 A BE 764299A
Authority
BE
Belgium
Prior art keywords
ethylenediamines
antifibrillatory
zolines
imida
naphthylanilide
Prior art date
Application number
BE764299A
Other languages
French (fr)
Inventor
Giannini Mario
Original Assignee
Malesci Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from BE764209A external-priority patent/BE764209A/en
Application filed by Malesci Sas filed Critical Malesci Sas
Priority to BE764299A priority Critical patent/BE764299A/en
Publication of BE764299A publication Critical patent/BE764299A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/24—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Novel ethylenediamines (I) or imidazolines (II) R1R2N-CH2CH2-NR3R4 are prepared (I) by reacting the corresp acid chlorides with the corresp. amine in anhyd. benzene where R1 = H or C6H9, R3=R4=Et and R2 is naphthoyl (opt. 6-Cl-substd) tetrahydronaphthoyl or quinaldyl; and (II R is an-N-(alpha-naphthylanilide)-residue) by reacting alpha-naphthylanilide with chlormethyl-2-imidazoline in dimethylformamide in presence of NaNH2. Et-esters are used for preparing (I) if R2 = and R4 = isopropyl if R3 = H. The products are antifibrillatory agents.
BE764299A 1971-03-12 1971-03-16 Antifibrillatory ethylenediamines or imida- - zolines BE764299A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BE764299A BE764299A (en) 1971-03-12 1971-03-16 Antifibrillatory ethylenediamines or imida- - zolines

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BE764209A BE764209A (en) 1970-03-14 1971-03-12 PRODUCTION PROCESS OF REINFORCED FIBROUS FIBERS
BE764299A BE764299A (en) 1971-03-12 1971-03-16 Antifibrillatory ethylenediamines or imida- - zolines

Publications (1)

Publication Number Publication Date
BE764299A true BE764299A (en) 1971-08-16

Family

ID=25656893

Family Applications (1)

Application Number Title Priority Date Filing Date
BE764299A BE764299A (en) 1971-03-12 1971-03-16 Antifibrillatory ethylenediamines or imida- - zolines

Country Status (1)

Country Link
BE (1) BE764299A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2525595A1 (en) * 1982-04-27 1983-10-28 Pharmuka Lab NOVEL ARENE AND HETEROARENECARBOXAMIDE DERIVATIVES AND THEIR USE AS MEDICAMENTS

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2525595A1 (en) * 1982-04-27 1983-10-28 Pharmuka Lab NOVEL ARENE AND HETEROARENECARBOXAMIDE DERIVATIVES AND THEIR USE AS MEDICAMENTS
EP0094271A3 (en) * 1982-04-27 1984-07-04 Pharmuka Laboratoires Aryl and heteroaryl carboxamide derivatives, process for their preparation and medicaments containing them
US4499094A (en) * 1982-04-27 1985-02-12 Pharmuka Laboratoires Derivatives of arene and hetero-arene carboxamides and their use as medicaments

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: MALESCI S.A.S. ISTITUTO FARMACOBIOLOGICO

Effective date: 19880331