DK1841874T3 - Leadersekvenser til at lede secernering af polypeptider og fremgangsmåder til fremstilling heraf - Google Patents

Leadersekvenser til at lede secernering af polypeptider og fremgangsmåder til fremstilling heraf

Info

Publication number
DK1841874T3
DK1841874T3 DK06719694.9T DK06719694T DK1841874T3 DK 1841874 T3 DK1841874 T3 DK 1841874T3 DK 06719694 T DK06719694 T DK 06719694T DK 1841874 T3 DK1841874 T3 DK 1841874T3
Authority
DK
Denmark
Prior art keywords
polypeptides
methods
heterologous
preparation
nucleic acid
Prior art date
Application number
DK06719694.9T
Other languages
English (en)
Inventor
Robert Forgan Halenbeck
Elizabeth Bosch
Thomas Linnemann
Ernestine Lee
Original Assignee
Five Prime Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Five Prime Therapeutics Inc filed Critical Five Prime Therapeutics Inc
Application granted granted Critical
Publication of DK1841874T3 publication Critical patent/DK1841874T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK06719694.9T 2005-01-27 2006-01-27 Leadersekvenser til at lede secernering af polypeptider og fremgangsmåder til fremstilling heraf DK1841874T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64701305P 2005-01-27 2005-01-27
PCT/US2006/002951 WO2006081430A2 (en) 2005-01-27 2006-01-27 Leader sequences for directing secretion of polypeptides and methods for production thereof

Publications (1)

Publication Number Publication Date
DK1841874T3 true DK1841874T3 (da) 2010-05-17

Family

ID=36741080

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06719694.9T DK1841874T3 (da) 2005-01-27 2006-01-27 Leadersekvenser til at lede secernering af polypeptider og fremgangsmåder til fremstilling heraf

Country Status (9)

Country Link
US (1) US20080286834A1 (da)
EP (1) EP1841874B1 (da)
JP (2) JP2008528033A (da)
AT (1) ATE454455T1 (da)
AU (1) AU2006207999A1 (da)
CA (1) CA2589895A1 (da)
DE (1) DE602006011574D1 (da)
DK (1) DK1841874T3 (da)
WO (1) WO2006081430A2 (da)

Families Citing this family (47)

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DE602006010874D1 (de) 2005-07-22 2010-01-14 Five Prime Therapeutics Inc Zusammensetzungen und verfahren zur behandlung von krankheiten mit fgfr-fusionsproteinen
US8044179B2 (en) 2005-09-13 2011-10-25 National Research Council Of Canada Methods and compositions for modulating tumor cell activity
US9060961B2 (en) * 2006-11-09 2015-06-23 University Of Washington Molecules and methods for treatment and detection of cancer
WO2009056330A1 (en) * 2007-10-31 2009-05-07 Eth Zurich Soluble truncated apom proteins and medical uses thereof
JP2011515489A (ja) * 2008-03-25 2011-05-19 アマランタス・セラピューティクス・インコーポレイテッド 神経変性障害
FR2933773B1 (fr) * 2008-07-10 2013-02-15 Biomerieux Sa Procede de dosage de la proteine disulfide isomerase pour le diagnostic in vitro du cancer colorectal
WO2010017198A2 (en) 2008-08-04 2010-02-11 Five Prime Therapeutics, Inc. Fgfr extracellular domain acidic region muteins
WO2010075194A1 (en) * 2008-12-22 2010-07-01 St. Jude Children's Research Hospital Prokaryotic expression of soluble, active dkk
JP2010183885A (ja) * 2009-02-13 2010-08-26 Kobe Univ タンパク質の製造方法およびそれに用いる発現ベクター
WO2011034940A1 (en) 2009-09-15 2011-03-24 Five Prime Therapeutics, Inc. Hair growth methods using fgfr4 extracellular domains
ES2600631T3 (es) 2009-11-13 2017-02-10 Five Prime Therapeutics, Inc. Uso de proteínas del dominio extracelular de FGFR1 para tratar cánceres caracterizados por mutaciones activadoras dependientes de ligando en FGFR2
US8802826B2 (en) 2009-11-24 2014-08-12 Alethia Biotherapeutics Inc. Anti-clusterin antibodies and antigen binding fragments and their use to reduce tumor volume
US8685931B2 (en) 2009-12-17 2014-04-01 Five Prime Therapeutics, Inc. Hair growth methods using FGFR3 extracellular domains
US8206715B2 (en) 2010-05-04 2012-06-26 Five Prime Therapeutics, Inc. Antibodies that bind colony stimulating factor 1 receptor (CSF1R)
WO2012006027A1 (en) 2010-06-28 2012-01-12 Five Prime Therapeutics, Inc. Fzd8 extracellular domains and fzd8 extracellular domain fusion molecules and treatments using same
EP2444495A1 (en) * 2010-10-20 2012-04-25 Algenics Secretion of recombinant polypeptides in the extracellular medium of diatoms
AU2011329125B2 (en) 2010-11-15 2015-07-30 Five Prime Therapeutics, Inc. Treatment of cancer with elevated dosages of soluble FGFR1 fusion proteins
US8481038B2 (en) 2010-11-15 2013-07-09 Five Prime Therapeutics, Inc. Treatment of cancer with elevated dosages of soluble FGFR1 fusion proteins
US8951972B2 (en) 2010-12-09 2015-02-10 Five Prime Therapeutics, Inc. FGFR1 extracellular domain combination therapies for lung cancer
CA2824805A1 (en) 2011-01-14 2012-07-19 Five Prime Therapeutics, Inc. Il-27 antagonists for treating inflammatory diseases
CN104168915A (zh) 2011-11-14 2014-11-26 戊瑞治疗有限公司 治疗癌症的方法
EA201491568A1 (ru) 2012-02-22 2014-11-28 Алетиа Байотерапьютикс Инк. Совместное применение ингибитора кластерина и ингибитора egfr для лечения рака
KR20150018533A (ko) 2012-05-11 2015-02-23 파이브 프라임 테라퓨틱스, 인크. 콜로니 자극 인자 1 수용체(csf1r)에 결속하는 항체들에 의한 질병 상태의 치료 방법
CA2876155C (en) 2012-06-08 2022-12-13 Ethris Gmbh Pulmonary delivery of mrna to non-lung target cells
CN104684582A (zh) 2012-08-31 2015-06-03 戊瑞治疗有限公司 用结合群落刺激因子1受体(csf1r)的抗体治疗病状的方法
EP3628335B1 (en) 2012-12-07 2023-11-08 Translate Bio, Inc. Lipidic nanoparticles for mrna delivery in the lungs
ES2692363T3 (es) 2013-03-14 2018-12-03 Translate Bio, Inc. Composiciones terapéuticas de ARNm y su uso para tratar enfermedades y trastornos
CN105452296B (zh) 2013-08-01 2020-09-25 戊瑞治疗有限公司 无岩藻糖基化抗fgfr2iiib抗体
WO2015200089A1 (en) 2014-06-23 2015-12-30 Five Prime Therapeutics, Inc. Methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (csf1r)
HUE054012T2 (hu) 2014-10-29 2021-08-30 Five Prime Therapeutics Inc Kombinációs terápia rák ellen
ES2843586T3 (es) 2014-12-22 2021-07-19 Five Prime Therapeutics Inc Anticuerpos dirigidos contra CSF1R para tratar la SVNP
SI3273992T1 (sl) 2015-03-23 2020-09-30 Jounce Therapeutics, Inc. Protitelesa proti ICOS
PL3283527T3 (pl) 2015-04-13 2021-06-14 Five Prime Therapeutics, Inc. Leczenie skojarzone nowotworów
TW201723190A (zh) 2015-10-22 2017-07-01 永斯醫療股份有限公司 用於測定icos表現之基因印記
JP7094223B2 (ja) 2016-04-25 2022-07-01 ファイブ プライム セラピューティクス， インコーポレイテッド 病的な筋肉減少および筋力低下の処置のためのｎｏｐｅ
MD3535298T2 (ro) 2016-11-02 2022-01-31 Jounce Therapeutics Inc Anticorpi ai PD-1 și utilizări ale acestora
CN109906030B (zh) 2016-11-04 2022-03-18 安健基因公司 用于产生仅重链抗体的经基因修饰的非人动物和方法
TWI685351B (zh) * 2016-12-29 2020-02-21 財團法人生物技術開發中心 延長蛋白質藥物體內半衰期的激肽原-1衍生胜肽
US20200031944A1 (en) 2017-03-31 2020-01-30 Five Prime Therapeutics, Inc. Combination therapy for cancer using anti-gitr antibodies
US20200024351A1 (en) 2017-04-03 2020-01-23 Jounce Therapeutics, Inc. Compositions and Methods for the Treatment of Cancer
US11667686B2 (en) 2017-06-06 2023-06-06 Kindred Biosciences, Inc. Erythropoietin and analogs for veterinary use
US10723798B2 (en) 2017-12-22 2020-07-28 Jounce Therapeutics, Inc. Antibodies to LILRB2
KR20210030405A (ko) 2018-07-09 2021-03-17 파이브 프라임 테라퓨틱스, 인크. Ilt4에 결합하는 항체
CN115087488A (zh) 2020-02-14 2022-09-20 震动疗法股份有限公司 与ccr8结合的抗体和融合蛋白及其用途
EP4114931A4 (en) * 2020-03-05 2024-05-01 Curie Co. Inc. METHODS FOR CELL PROTEIN EXPRESSION OF MATURE POLYPEPTIDES DERIVED FROM ZYMOGENS AND PROPROTEINS
WO2022033419A2 (en) 2020-08-10 2022-02-17 Shanghai Xbh Biotechnology Co., Ltd. Compositions and methods for treating autoimmune diseases and cancers by targeting igsf8
WO2023235699A1 (en) 2022-05-31 2023-12-07 Jounce Therapeutics, Inc. Antibodies to lilrb4 and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5712114A (en) * 1995-06-06 1998-01-27 Basf Aktiengesellschaft Compositions for expression of proteins in host cells using a preprocollagen signal sequence
ATE223491T1 (de) * 1998-08-17 2002-09-15 Europ Lab Molekularbiolog Verfahren zur reinigung von biomolekül- oder proteinkomplexen
US20080242603A1 (en) * 2004-02-20 2008-10-02 Yan Wang Novel Apo2L and IL-24 Polypeptides, Polynucleotides, and Methods of Their Use
EP2287310B1 (en) * 2004-07-22 2015-05-06 Five Prime Therapeutics, Inc. Compositions and methods using MGD-CSF in disease treatment

Also Published As

Publication number Publication date
ATE454455T1 (de) 2010-01-15
EP1841874B1 (en) 2010-01-06
JP2008528033A (ja) 2008-07-31
JP2009131268A (ja) 2009-06-18
AU2006207999A1 (en) 2006-08-03
CA2589895A1 (en) 2006-08-03
US20080286834A1 (en) 2008-11-20
DE602006011574D1 (de) 2010-02-25
WO2006081430A2 (en) 2006-08-03
EP1841874A2 (en) 2007-10-10
WO2006081430A3 (en) 2007-04-05
WO2006081430A9 (en) 2006-11-30

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