DK1841725T3 - Fremgangsmåde til oprensning af gabapentin - Google Patents

Fremgangsmåde til oprensning af gabapentin

Info

Publication number
DK1841725T3
DK1841725T3 DK05823475T DK05823475T DK1841725T3 DK 1841725 T3 DK1841725 T3 DK 1841725T3 DK 05823475 T DK05823475 T DK 05823475T DK 05823475 T DK05823475 T DK 05823475T DK 1841725 T3 DK1841725 T3 DK 1841725T3
Authority
DK
Denmark
Prior art keywords
gabapentin
purification
addition
relates
solution
Prior art date
Application number
DK05823475T
Other languages
Danish (da)
English (en)
Inventor
Roberto Giovanetti
Andrea Nicoli
Livius Cotarca
Original Assignee
Zach System Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zach System Spa filed Critical Zach System Spa
Application granted granted Critical
Publication of DK1841725T3 publication Critical patent/DK1841725T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/54—Spiro-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/38—Separation; Purification; Stabilisation; Use of additives
    • C07C227/40—Separation; Purification
    • C07C227/42—Crystallisation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK05823475T 2004-12-17 2005-12-15 Fremgangsmåde til oprensning af gabapentin DK1841725T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT002418A ITMI20042418A1 (it) 2004-12-17 2004-12-17 Processo per la purificazione della gabapentina
PCT/EP2005/056817 WO2006064041A1 (en) 2004-12-17 2005-12-15 A process for the purification of gabapentin

Publications (1)

Publication Number Publication Date
DK1841725T3 true DK1841725T3 (da) 2009-06-15

Family

ID=36353861

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05823475T DK1841725T3 (da) 2004-12-17 2005-12-15 Fremgangsmåde til oprensning af gabapentin

Country Status (15)

Country Link
US (1) US7989658B2 (de)
EP (1) EP1841725B1 (de)
JP (1) JP5101296B2 (de)
AT (1) ATE426591T1 (de)
CA (1) CA2590232C (de)
CY (1) CY1109039T1 (de)
DE (1) DE602005013579D1 (de)
DK (1) DK1841725T3 (de)
ES (1) ES2322086T3 (de)
HR (1) HRP20090337T1 (de)
IL (1) IL183745A (de)
IT (1) ITMI20042418A1 (de)
PT (1) PT1841725E (de)
SI (1) SI1841725T1 (de)
WO (1) WO2006064041A1 (de)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4894476A (en) * 1988-05-02 1990-01-16 Warner-Lambert Company Gabapentin monohydrate and a process for producing the same
IT1319234B1 (it) * 2000-10-23 2003-09-26 Zambon Spa Processo di preparazione di gabapentina.
IT1319674B1 (it) * 2000-12-01 2003-10-23 Erregierre Spa Processo per la preparazione dell'acido1-(aminometil)cicloesanacetico.
US20040063994A1 (en) * 2001-03-16 2004-04-01 Paolo Rossi Process for the preparation of cyclic amino acids
ITMI20012750A1 (it) * 2001-12-21 2003-06-21 Procos Spa Processo per la produzione dell'acido 1-(amminometil)-cicloesil-acetico in forma pura
ITMI20022071A1 (it) * 2002-10-01 2004-04-02 Erregierre Spa Processo di sintesi dell'acido 1-(aminometil)cicloesanacetico cloridato.
WO2004093779A2 (en) * 2003-04-21 2004-11-04 Matrix Laboratories Ltd Process for the preparation of gabapentin form-ii
ITMI20031247A1 (it) 2003-06-20 2004-12-21 Zambon Spa Processo per la purificazione di gabapentina
ITMI20032456A1 (it) 2003-12-16 2005-06-17 Zambon Spa Processo per la purificazione di gabapentina
ITMI20040579A1 (it) * 2004-03-25 2004-06-25 Zambon Spa Processo di preparazione di gabapentina

Also Published As

Publication number Publication date
PT1841725E (pt) 2009-04-27
ATE426591T1 (de) 2009-04-15
CA2590232A1 (en) 2006-06-22
IL183745A (en) 2011-04-28
ES2322086T3 (es) 2009-06-16
CA2590232C (en) 2013-02-12
ITMI20042418A1 (it) 2005-03-17
SI1841725T1 (sl) 2009-10-31
WO2006064041A1 (en) 2006-06-22
JP5101296B2 (ja) 2012-12-19
JP2008524164A (ja) 2008-07-10
CY1109039T1 (el) 2014-07-02
IL183745A0 (en) 2007-09-20
US20090292138A1 (en) 2009-11-26
US7989658B2 (en) 2011-08-02
EP1841725A1 (de) 2007-10-10
HRP20090337T1 (en) 2009-07-31
DE602005013579D1 (de) 2009-05-07
EP1841725B1 (de) 2009-03-25

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