DE602005013579D1 - Verfahren zur aufreinigung von gabapentin - Google Patents

Verfahren zur aufreinigung von gabapentin

Info

Publication number
DE602005013579D1
DE602005013579D1 DE602005013579T DE602005013579T DE602005013579D1 DE 602005013579 D1 DE602005013579 D1 DE 602005013579D1 DE 602005013579 T DE602005013579 T DE 602005013579T DE 602005013579 T DE602005013579 T DE 602005013579T DE 602005013579 D1 DE602005013579 D1 DE 602005013579D1
Authority
DE
Germany
Prior art keywords
gabapentin
addition
relates
purifying
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005013579T
Other languages
English (en)
Inventor
Roberto Giovanetti
Andrea Nicoli
Livius Cotarca
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zach System SpA
Original Assignee
Zach System SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zach System SpA filed Critical Zach System SpA
Publication of DE602005013579D1 publication Critical patent/DE602005013579D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/54—Spiro-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/38—Separation; Purification; Stabilisation; Use of additives
    • C07C227/40—Separation; Purification
    • C07C227/42—Crystallisation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE602005013579T 2004-12-17 2005-12-15 Verfahren zur aufreinigung von gabapentin Active DE602005013579D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT002418A ITMI20042418A1 (it) 2004-12-17 2004-12-17 Processo per la purificazione della gabapentina
PCT/EP2005/056817 WO2006064041A1 (en) 2004-12-17 2005-12-15 A process for the purification of gabapentin

Publications (1)

Publication Number Publication Date
DE602005013579D1 true DE602005013579D1 (de) 2009-05-07

Family

ID=36353861

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005013579T Active DE602005013579D1 (de) 2004-12-17 2005-12-15 Verfahren zur aufreinigung von gabapentin

Country Status (15)

Country Link
US (1) US7989658B2 (de)
EP (1) EP1841725B1 (de)
JP (1) JP5101296B2 (de)
AT (1) ATE426591T1 (de)
CA (1) CA2590232C (de)
CY (1) CY1109039T1 (de)
DE (1) DE602005013579D1 (de)
DK (1) DK1841725T3 (de)
ES (1) ES2322086T3 (de)
HR (1) HRP20090337T1 (de)
IL (1) IL183745A (de)
IT (1) ITMI20042418A1 (de)
PT (1) PT1841725E (de)
SI (1) SI1841725T1 (de)
WO (1) WO2006064041A1 (de)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4894476A (en) * 1988-05-02 1990-01-16 Warner-Lambert Company Gabapentin monohydrate and a process for producing the same
IT1319234B1 (it) * 2000-10-23 2003-09-26 Zambon Spa Processo di preparazione di gabapentina.
IT1319674B1 (it) * 2000-12-01 2003-10-23 Erregierre Spa Processo per la preparazione dell'acido1-(aminometil)cicloesanacetico.
US20040063994A1 (en) * 2001-03-16 2004-04-01 Paolo Rossi Process for the preparation of cyclic amino acids
ITMI20012750A1 (it) * 2001-12-21 2003-06-21 Procos Spa Processo per la produzione dell'acido 1-(amminometil)-cicloesil-acetico in forma pura
ITMI20022071A1 (it) * 2002-10-01 2004-04-02 Erregierre Spa Processo di sintesi dell'acido 1-(aminometil)cicloesanacetico cloridato.
WO2004093779A2 (en) * 2003-04-21 2004-11-04 Matrix Laboratories Ltd Process for the preparation of gabapentin form-ii
ITMI20031247A1 (it) 2003-06-20 2004-12-21 Zambon Spa Processo per la purificazione di gabapentina
ITMI20032456A1 (it) 2003-12-16 2005-06-17 Zambon Spa Processo per la purificazione di gabapentina
ITMI20040579A1 (it) * 2004-03-25 2004-06-25 Zambon Spa Processo di preparazione di gabapentina

Also Published As

Publication number Publication date
PT1841725E (pt) 2009-04-27
ATE426591T1 (de) 2009-04-15
CA2590232A1 (en) 2006-06-22
IL183745A (en) 2011-04-28
ES2322086T3 (es) 2009-06-16
CA2590232C (en) 2013-02-12
ITMI20042418A1 (it) 2005-03-17
SI1841725T1 (sl) 2009-10-31
WO2006064041A1 (en) 2006-06-22
DK1841725T3 (da) 2009-06-15
JP5101296B2 (ja) 2012-12-19
JP2008524164A (ja) 2008-07-10
CY1109039T1 (el) 2014-07-02
IL183745A0 (en) 2007-09-20
US20090292138A1 (en) 2009-11-26
US7989658B2 (en) 2011-08-02
EP1841725A1 (de) 2007-10-10
HRP20090337T1 (en) 2009-07-31
EP1841725B1 (de) 2009-03-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition