DK183589A - Farmaceutisk middel indeholdende en 12-leddet macrolid-forbindelse og fremgangsmaade til fremstilling heraf - Google Patents

Farmaceutisk middel indeholdende en 12-leddet macrolid-forbindelse og fremgangsmaade til fremstilling heraf

Info

Publication number
DK183589A
DK183589A DK183589A DK183589A DK183589A DK 183589 A DK183589 A DK 183589A DK 183589 A DK183589 A DK 183589A DK 183589 A DK183589 A DK 183589A DK 183589 A DK183589 A DK 183589A
Authority
DK
Denmark
Prior art keywords
macrolid
preparing
joint
procedure
compound
Prior art date
Application number
DK183589A
Other languages
Danish (da)
English (en)
Other versions
DK183589D0 (da
Inventor
Jaswant Singh Gidda
Herbert Andrew Kirst
David Wayne Robertson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK183589D0 publication Critical patent/DK183589D0/da
Publication of DK183589A publication Critical patent/DK183589A/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK183589A 1988-04-18 1989-04-17 Farmaceutisk middel indeholdende en 12-leddet macrolid-forbindelse og fremgangsmaade til fremstilling heraf DK183589A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/182,645 US4920102A (en) 1988-04-18 1988-04-18 Method for treating gastrointestinal disorders

Publications (2)

Publication Number Publication Date
DK183589D0 DK183589D0 (da) 1989-04-17
DK183589A true DK183589A (da) 1989-10-19

Family

ID=22669415

Family Applications (1)

Application Number Title Priority Date Filing Date
DK183589A DK183589A (da) 1988-04-18 1989-04-17 Farmaceutisk middel indeholdende en 12-leddet macrolid-forbindelse og fremgangsmaade til fremstilling heraf

Country Status (22)

Country Link
US (1) US4920102A (ja)
EP (1) EP0349100B1 (ja)
JP (1) JPH0825882B2 (ja)
KR (1) KR970009580B1 (ja)
CN (1) CN1023017C (ja)
AR (1) AR244699A1 (ja)
AT (1) ATE139782T1 (ja)
AU (1) AU616746B2 (ja)
CA (1) CA1328257C (ja)
DE (1) DE68926728T2 (ja)
DK (1) DK183589A (ja)
ES (1) ES2088388T3 (ja)
GR (1) GR3020604T3 (ja)
HU (1) HU206365B (ja)
IE (1) IE72969B1 (ja)
IL (1) IL89996A (ja)
MX (1) MX15701A (ja)
NZ (1) NZ228768A (ja)
PH (1) PH26391A (ja)
PT (1) PT90293B (ja)
RU (1) RU2086560C1 (ja)
ZA (1) ZA892801B (ja)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5106961A (en) * 1987-05-26 1992-04-21 Eli Lilly And Company Erythromycin ring-contracted derivatives
US5068221A (en) * 1989-05-09 1991-11-26 Mathias John R Treatment of motility disorders with a gnrh analog
US5434136A (en) * 1990-12-14 1995-07-18 Mathias; John R. Treatment of motility disorders with a GNRH analog
ES2091471T3 (es) * 1991-04-09 1996-11-01 Abbott Lab Agentes procineticos a base de lactama macrociclica.
US5523401A (en) * 1991-04-09 1996-06-04 Abbott Laboratories Macrocyclic lactam prokinetic agents
DE4200145A1 (de) * 1992-01-07 1993-07-08 Kali Chemie Pharma Gmbh 7,10-epoxy-oxacyclododecan-derivate, verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
ATE164848T1 (de) * 1992-01-21 1998-04-15 Abbott Lab 4''-deoxyerythromycinderivate
DE69302938T2 (de) * 1992-03-19 1996-10-17 Kitasato Inst Erythromycinderivate, Herstellung und Verwendung davon
FR2697524B1 (fr) * 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
US5712253A (en) * 1996-06-18 1998-01-27 Abbott Laboratories Macrocyclic 13-membered ring derivatives of erythromycins A and B
DE19644195A1 (de) * 1996-10-24 1998-04-30 Solvay Pharm Gmbh 10,13,15-Trioxatricyclo[9.2.1.1.·9·.·6·]-pentadecanon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US6165985A (en) * 1998-02-13 2000-12-26 Solvay Pharmaceuticals Gmbh 11-acetyl-12,13-dioxabicyclo[8.2.1]-tridecenone derivatives, processes for their preparation and pharmaceutical compositions comprising them
DE19805822B4 (de) * 1998-02-13 2009-02-05 Solvay Pharmaceuticals Gmbh 11-Acetyl-12,13-dioxabicyclo[8.2.1]tridecenon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US5972898A (en) * 1998-03-27 1999-10-26 Abbott Laboratories 3',3-N-bis-substituted macrolide LHRH antagonists
US5955440A (en) * 1998-03-27 1999-09-21 Abbott Laboratories Macrolide LHRH antagonists
US6387885B1 (en) 1998-08-26 2002-05-14 Abbott Laboratories 3′,3′-N-bis-desmethyl-3′-N-cycloalkyl erythromycin derivatives as LHRH antagonists
US6020521A (en) * 1998-08-26 2000-02-01 Abbott Laboratories Macrolide LHRH antagonists
US6451806B2 (en) 1999-09-29 2002-09-17 Adolor Corporation Methods and compositions involving opioids and antagonists thereof
US6469030B2 (en) 1999-11-29 2002-10-22 Adolor Corporation Methods for the treatment and prevention of ileus
DE60027015T2 (de) * 2000-08-17 2006-10-05 The Kitasato Institute Pseudoerythromycin-derivate
GB0123400D0 (en) 2001-09-28 2001-11-21 Novartis Ag Organic compounds
US20040067896A1 (en) * 2002-07-25 2004-04-08 The Kitasato Institute Novel pseudoerythromycin derivatives
US7521428B2 (en) * 2002-10-29 2009-04-21 The Kitasato Institute Macrolide derivatives having effect of potentiating antifungal activity
JP4928261B2 (ja) 2003-06-18 2012-05-09 トランザイム・ファーマ・インコーポレイテッド モチリン受容体の大環状拮抗薬
EP1960414A4 (en) * 2005-12-08 2008-12-17 Pfizer METHOD FOR DEMETHYLATING THE 3-DIMETHYLAMINOGRUPPE OF ERYTHROMYCIN COMPOUNDS
EP2431380A3 (en) 2006-09-11 2013-07-03 Tranzyme Pharma, Inc. Macrocyclic antagonist of the motilin receptor for treatment of gastrointestinal dysmotility disorders
US20080287371A1 (en) * 2007-05-17 2008-11-20 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex
FR2995605B1 (fr) * 2012-09-18 2014-09-19 Sanofi Sa Derives de macrolides, leur preparation et leur application therapeutique.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4547491A (en) * 1984-07-18 1985-10-15 Merck & Co., Inc. C-8A-Oxo-avermectin and milbemycin derivatives, pharmaceutical compositions and method of use
JPS6187625A (ja) * 1984-10-05 1986-05-06 Satoshi Omura 消化管収縮運動促進剤
DE3689758T2 (de) * 1985-08-31 1994-08-18 Kitasato Inst Erythromycinderivat und Verfahren zu dessen Herstellung.
CA1321581C (en) * 1987-05-26 1993-08-24 Herbert A. Kirst Ring-contracted macrolides

Also Published As

Publication number Publication date
ATE139782T1 (de) 1996-07-15
EP0349100A2 (en) 1990-01-03
US4920102A (en) 1990-04-24
CN1037517A (zh) 1989-11-29
ZA892801B (en) 1990-12-28
PT90293A (pt) 1989-11-10
DE68926728T2 (de) 1996-11-28
PH26391A (en) 1992-07-02
ES2088388T3 (es) 1996-08-16
PT90293B (pt) 1994-07-29
EP0349100A3 (en) 1991-11-13
IE72969B1 (en) 1997-05-07
EP0349100B1 (en) 1996-06-26
RU2086560C1 (ru) 1997-08-10
HU206365B (en) 1992-10-28
AR244699A1 (es) 1993-11-30
CA1328257C (en) 1994-04-05
KR970009580B1 (en) 1997-06-14
KR900016220A (ko) 1990-11-12
NZ228768A (en) 1990-10-26
HUT49625A (en) 1989-10-30
DK183589D0 (da) 1989-04-17
JPH01311096A (ja) 1989-12-15
GR3020604T3 (en) 1996-10-31
AU3310789A (en) 1989-10-19
IL89996A (en) 1994-08-26
MX15701A (es) 1993-11-01
CN1023017C (zh) 1993-12-08
IE891224L (en) 1989-10-18
JPH0825882B2 (ja) 1996-03-13
AU616746B2 (en) 1991-11-07
IL89996A0 (en) 1989-12-15
DE68926728D1 (de) 1996-08-01

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