DK182386A - Carbapenemmellemprodukter - Google Patents

Carbapenemmellemprodukter Download PDF

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Publication number
DK182386A
DK182386A DK182386A DK182386A DK182386A DK 182386 A DK182386 A DK 182386A DK 182386 A DK182386 A DK 182386A DK 182386 A DK182386 A DK 182386A DK 182386 A DK182386 A DK 182386A
Authority
DK
Denmark
Prior art keywords
carbapenes
intermediate products
products
alkyl
useful
Prior art date
Application number
DK182386A
Other languages
Danish (da)
English (en)
Other versions
DK182386D0 (da
Inventor
Yasutsugu Ueda
Guy Roberge
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of DK182386D0 publication Critical patent/DK182386D0/da
Publication of DK182386A publication Critical patent/DK182386A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/39Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups
    • C07C205/42Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups having nitro groups or esterified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C245/00Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
    • C07C245/12Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom
    • C07C245/14Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom having diazo groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C245/18Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom having diazo groups bound to acyclic carbon atoms of a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/12Organo silicon halides
    • C07F7/16Preparation thereof from silicon and halogenated hydrocarbons direct synthesis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1896Compounds having one or more Si-O-acyl linkages
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK182386A 1985-04-22 1986-04-21 Carbapenemmellemprodukter DK182386A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72559485 1985-04-22
US06/725,594 US4683296A (en) 1983-03-07 1985-04-22 Carbapenem intermediates

Publications (2)

Publication Number Publication Date
DK182386D0 DK182386D0 (da) 1986-04-21
DK182386A true DK182386A (da) 1986-10-23

Family

ID=24915191

Family Applications (1)

Application Number Title Priority Date Filing Date
DK182386A DK182386A (da) 1985-04-22 1986-04-21 Carbapenemmellemprodukter

Country Status (35)

Country Link
US (1) US4683296A (pt)
JP (1) JPS61275284A (pt)
KR (1) KR890004347B1 (pt)
CN (1) CN86102077A (pt)
AR (1) AR244236A1 (pt)
AT (1) AT386208B (pt)
AU (1) AU599022B2 (pt)
BE (1) BE904645A (pt)
CA (1) CA1302426C (pt)
CH (1) CH667273A5 (pt)
CS (1) CS266585B2 (pt)
DD (1) DD251352A5 (pt)
DE (1) DE3613366A1 (pt)
DK (1) DK182386A (pt)
ES (1) ES8708234A1 (pt)
FI (1) FI861633A (pt)
FR (1) FR2580653B1 (pt)
GB (1) GB2173801B (pt)
GR (1) GR861064B (pt)
HU (1) HU195824B (pt)
IE (1) IE59042B1 (pt)
IL (1) IL78533A (pt)
IT (1) IT1213061B (pt)
LU (1) LU86401A1 (pt)
MY (1) MY102926A (pt)
NL (1) NL8601010A (pt)
NO (1) NO861558L (pt)
NZ (1) NZ215263A (pt)
OA (1) OA08235A (pt)
PT (1) PT82435B (pt)
SE (1) SE8601824L (pt)
YU (1) YU43696B (pt)
ZA (1) ZA862987B (pt)
ZM (1) ZM6286A1 (pt)
ZW (1) ZW8986A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4772683A (en) * 1986-02-24 1988-09-20 Bristol-Myers Company High percentage beta-yield synthesis of carbapenem intermediates
JP2675625B2 (ja) * 1989-01-12 1997-11-12 鐘淵化学工業株式会社 エノールシリルエーテル化合物の製造方法
NZ234411A (en) * 1989-07-18 1991-05-28 Merck & Co Inc Preparation of 2-diazo-3-silyloxy-3-butenoate esters
US5340927A (en) * 1989-07-18 1994-08-23 Merck & Co., Inc. Process for the preparation of 2-diazo-3-trisubstituted silyloxy 3-butenoates
DE4014649A1 (de) * 1990-05-08 1991-11-14 Hoechst Ag Neue mehrfunktionelle verbindungen mit (alpha)-diazo-ss-ketoester- und sulfonsaeureester-einheiten, verfahren zu ihrer herstellung und deren verwendung
JP2000166962A (ja) * 1998-12-08 2000-06-20 Tatsu Ifukube 触覚刺激装置及び方法
ATE454388T1 (de) 2003-08-28 2010-01-15 Ranbaxy Lab Ltd Verfahren zur herstellung von estern von 2-diazo- 3-trimethylsilyloxy-3-butensäure
US20070037971A1 (en) * 2005-07-29 2007-02-15 Meeran Hashim Nizar P N Process for desilylation of carbapenem intermediates
EP2326648B1 (en) * 2008-07-30 2012-09-19 Ranbaxy Laboratories Limited Process for the preparation of carbapenem compounds
WO2011048583A1 (en) 2009-10-23 2011-04-28 Ranbaxy Laboratories Limited Process for the preparation of carbapenem compounds
CN102690282A (zh) * 2011-07-07 2012-09-26 深圳市海滨制药有限公司 晶体形式的1β甲基碳青霉烯类抗生素中间体及其制备方法
CN102643211A (zh) * 2012-04-10 2012-08-22 平顶山佳瑞高科实业有限公司 一种2-重氮乙酰乙酸对硝基苄酯的制备方法
US10695322B2 (en) 2016-01-29 2020-06-30 The Johns Hopkins University Inhibitors of bacterial growth
CN106565535B (zh) * 2016-11-15 2018-07-17 山西师范大学 2-重氮-1-芳基酮类化合物的制备方法
CN107556212B (zh) * 2017-09-14 2020-03-24 台州昌霖化工科技有限公司 一种制备2-重氮乙酰乙酸对硝基苄酯的方法
CN114516820A (zh) * 2022-02-25 2022-05-20 山东艾孚特科技有限公司 一种制备2-重氮乙酰乙酸对硝基苄酯的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0075026B1 (en) * 1981-04-03 1986-12-17 Matsushita Electric Industrial Co., Ltd. Method of cooking
US4444685A (en) * 1981-04-27 1984-04-24 Merck & Co., Inc. Stereospecific synthesis of thienamycin from penicillin
CA1190236A (en) * 1981-10-23 1985-07-09 Edward J.J. Grabowski Antibiotic synthesis
US4525582A (en) * 1982-06-22 1985-06-25 Merck & Co., Inc. Silyl, benzyl, p-nitrobenyl, or methyl esters of diazoacetate, a synthon used in the conversion of penicillin to thienamycin
CA1269978A (en) * 1982-09-28 1990-06-05 Choung U. Kim Carbapenem antibiotics
CA1220215A (en) * 1983-03-07 1987-04-07 Yasutsugu Ueda Carbapenem intermediates

Also Published As

Publication number Publication date
OA08235A (fr) 1987-10-30
KR890004347B1 (ko) 1989-10-31
IE861047L (en) 1986-10-22
ZM6286A1 (en) 1987-04-30
AT386208B (de) 1988-07-25
IT8620164A0 (it) 1986-04-21
DE3613366A1 (de) 1986-11-20
ES8708234A1 (es) 1987-10-01
SE8601824D0 (sv) 1986-04-21
PT82435B (pt) 1988-08-17
YU43696B (en) 1989-10-31
IL78533A0 (en) 1986-08-31
AU5616786A (en) 1986-11-06
KR860008191A (ko) 1986-11-12
AR244236A1 (es) 1993-10-29
CS266585B2 (en) 1990-01-12
ES554217A0 (es) 1987-10-01
MY102926A (en) 1993-03-31
SE8601824L (sv) 1986-10-23
GB2173801B (en) 1989-08-23
IT1213061B (it) 1989-12-07
JPS6358836B2 (pt) 1988-11-17
ATA106886A (de) 1987-12-15
HU195824B (en) 1988-07-28
NL8601010A (nl) 1986-11-17
NZ215263A (en) 1989-03-29
DK182386D0 (da) 1986-04-21
ZA862987B (en) 1987-12-30
IE59042B1 (en) 1993-12-15
FI861633A (fi) 1986-10-23
BE904645A (fr) 1986-10-21
US4683296A (en) 1987-07-28
NO861558L (no) 1986-10-23
IL78533A (en) 1992-05-25
CH667273A5 (de) 1988-09-30
GB2173801A (en) 1986-10-22
CA1302426C (en) 1992-06-02
LU86401A1 (fr) 1986-11-05
HUT41040A (en) 1987-03-30
PT82435A (en) 1986-05-01
YU65886A (en) 1988-04-30
GR861064B (en) 1986-09-01
FI861633A0 (fi) 1986-04-17
AU599022B2 (en) 1990-07-12
FR2580653B1 (fr) 1989-06-16
DD251352A5 (de) 1987-11-11
ZW8986A1 (en) 1986-12-03
GB8609662D0 (en) 1986-05-29
FR2580653A1 (fr) 1986-10-24
CS287386A2 (en) 1989-04-14
CN86102077A (zh) 1987-01-28
JPS61275284A (ja) 1986-12-05

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