OA08235A - Composés intermediaires de carbapénem et leur procédé de préparation. - Google Patents

Composés intermediaires de carbapénem et leur procédé de préparation.

Info

Publication number
OA08235A
OA08235A OA58839A OA58839A OA08235A OA 08235 A OA08235 A OA 08235A OA 58839 A OA58839 A OA 58839A OA 58839 A OA58839 A OA 58839A OA 08235 A OA08235 A OA 08235A
Authority
OA
OAPI
Prior art keywords
carbapenem
preparation process
intermediate compounds
compounds
preparation
Prior art date
Application number
OA58839A
Other languages
English (en)
Inventor
Guy Roberge
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of OA08235A publication Critical patent/OA08235A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/39—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups
    • C07C205/42—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups having nitro groups or esterified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C245/00—Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
    • C07C245/12—Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom
    • C07C245/14—Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom having diazo groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C245/18—Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom having diazo groups bound to acyclic carbon atoms of a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/12—Organo silicon halides
    • C07F7/16—Preparation thereof from silicon and halogenated hydrocarbons direct synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1896—Compounds having one or more Si-O-acyl linkages
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
OA58839A 1985-04-22 1986-04-18 Composés intermediaires de carbapénem et leur procédé de préparation. OA08235A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/725,594 US4683296A (en) 1983-03-07 1985-04-22 Carbapenem intermediates

Publications (1)

Publication Number Publication Date
OA08235A true OA08235A (fr) 1987-10-30

Family

ID=24915191

Family Applications (1)

Application Number Title Priority Date Filing Date
OA58839A OA08235A (fr) 1985-04-22 1986-04-18 Composés intermediaires de carbapénem et leur procédé de préparation.

Country Status (35)

Country Link
US (1) US4683296A (fr)
JP (1) JPS61275284A (fr)
KR (1) KR890004347B1 (fr)
CN (1) CN86102077A (fr)
AR (1) AR244236A1 (fr)
AT (1) AT386208B (fr)
AU (1) AU599022B2 (fr)
BE (1) BE904645A (fr)
CA (1) CA1302426C (fr)
CH (1) CH667273A5 (fr)
CS (1) CS266585B2 (fr)
DD (1) DD251352A5 (fr)
DE (1) DE3613366A1 (fr)
DK (1) DK182386A (fr)
ES (1) ES8708234A1 (fr)
FI (1) FI861633A (fr)
FR (1) FR2580653B1 (fr)
GB (1) GB2173801B (fr)
GR (1) GR861064B (fr)
HU (1) HU195824B (fr)
IE (1) IE59042B1 (fr)
IL (1) IL78533A (fr)
IT (1) IT1213061B (fr)
LU (1) LU86401A1 (fr)
MY (1) MY102926A (fr)
NL (1) NL8601010A (fr)
NO (1) NO861558L (fr)
NZ (1) NZ215263A (fr)
OA (1) OA08235A (fr)
PT (1) PT82435B (fr)
SE (1) SE8601824L (fr)
YU (1) YU43696B (fr)
ZA (1) ZA862987B (fr)
ZM (1) ZM6286A1 (fr)
ZW (1) ZW8986A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4772683A (en) * 1986-02-24 1988-09-20 Bristol-Myers Company High percentage beta-yield synthesis of carbapenem intermediates
JP2675625B2 (ja) * 1989-01-12 1997-11-12 鐘淵化学工業株式会社 エノールシリルエーテル化合物の製造方法
NZ234411A (en) * 1989-07-18 1991-05-28 Merck & Co Inc Preparation of 2-diazo-3-silyloxy-3-butenoate esters
US5340927A (en) * 1989-07-18 1994-08-23 Merck & Co., Inc. Process for the preparation of 2-diazo-3-trisubstituted silyloxy 3-butenoates
DE4014649A1 (de) * 1990-05-08 1991-11-14 Hoechst Ag Neue mehrfunktionelle verbindungen mit (alpha)-diazo-ss-ketoester- und sulfonsaeureester-einheiten, verfahren zu ihrer herstellung und deren verwendung
JP2000166962A (ja) * 1998-12-08 2000-06-20 Tatsu Ifukube 触覚刺激装置及び方法
ATE454388T1 (de) 2003-08-28 2010-01-15 Ranbaxy Lab Ltd Verfahren zur herstellung von estern von 2-diazo- 3-trimethylsilyloxy-3-butensäure
US20070037971A1 (en) * 2005-07-29 2007-02-15 Meeran Hashim Nizar P N Process for desilylation of carbapenem intermediates
CA2732619A1 (fr) * 2008-07-30 2010-02-04 Ranbaxy Laboratories Limited Procede de preparation de composes carbapenemes
WO2011048583A1 (fr) 2009-10-23 2011-04-28 Ranbaxy Laboratories Limited Procédé pour la préparation de composés de carbapénème
CN102690282A (zh) * 2011-07-07 2012-09-26 深圳市海滨制药有限公司 晶体形式的1β甲基碳青霉烯类抗生素中间体及其制备方法
CN102643211A (zh) * 2012-04-10 2012-08-22 平顶山佳瑞高科实业有限公司 一种2-重氮乙酰乙酸对硝基苄酯的制备方法
US10695322B2 (en) 2016-01-29 2020-06-30 The Johns Hopkins University Inhibitors of bacterial growth
CN106565535B (zh) * 2016-11-15 2018-07-17 山西师范大学 2-重氮-1-芳基酮类化合物的制备方法
CN107556212B (zh) * 2017-09-14 2020-03-24 台州昌霖化工科技有限公司 一种制备2-重氮乙酰乙酸对硝基苄酯的方法
CN114516820A (zh) * 2022-02-25 2022-05-20 山东艾孚特科技有限公司 一种制备2-重氮乙酰乙酸对硝基苄酯的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982003445A1 (fr) * 1981-04-03 1982-10-14 Nagamoto Shunichi Unite d'affichage d'un dispositif de cuisson permettant d'afficher de maniere selective des signaux d'images provenant de plusieurs sources de signaux d'images
US4444685A (en) * 1981-04-27 1984-04-24 Merck & Co., Inc. Stereospecific synthesis of thienamycin from penicillin
CA1190236A (fr) * 1981-10-23 1985-07-09 Edward J.J. Grabowski Synthese d'un antibiotique
US4525582A (en) * 1982-06-22 1985-06-25 Merck & Co., Inc. Silyl, benzyl, p-nitrobenyl, or methyl esters of diazoacetate, a synthon used in the conversion of penicillin to thienamycin
CA1269978A (fr) * 1982-09-28 1990-06-05 Choung U. Kim Antibiotiques a base de carbapenemes
CA1220215A (fr) * 1983-03-07 1987-04-07 Yasutsugu Ueda Intermediaires du carbapenem

Also Published As

Publication number Publication date
GB8609662D0 (en) 1986-05-29
DD251352A5 (de) 1987-11-11
NO861558L (no) 1986-10-23
DK182386D0 (da) 1986-04-21
CS287386A2 (en) 1989-04-14
FI861633A (fi) 1986-10-23
IE59042B1 (en) 1993-12-15
HU195824B (en) 1988-07-28
CS266585B2 (en) 1990-01-12
FI861633A0 (fi) 1986-04-17
FR2580653B1 (fr) 1989-06-16
ZW8986A1 (en) 1986-12-03
YU43696B (en) 1989-10-31
SE8601824D0 (sv) 1986-04-21
ZM6286A1 (en) 1987-04-30
US4683296A (en) 1987-07-28
FR2580653A1 (fr) 1986-10-24
AR244236A1 (es) 1993-10-29
AU5616786A (en) 1986-11-06
GB2173801B (en) 1989-08-23
ES8708234A1 (es) 1987-10-01
ES554217A0 (es) 1987-10-01
IT8620164A0 (it) 1986-04-21
AT386208B (de) 1988-07-25
NL8601010A (nl) 1986-11-17
KR890004347B1 (ko) 1989-10-31
JPS6358836B2 (fr) 1988-11-17
DE3613366A1 (de) 1986-11-20
BE904645A (fr) 1986-10-21
IL78533A (en) 1992-05-25
JPS61275284A (ja) 1986-12-05
IL78533A0 (en) 1986-08-31
NZ215263A (en) 1989-03-29
ATA106886A (de) 1987-12-15
SE8601824L (sv) 1986-10-23
IT1213061B (it) 1989-12-07
IE861047L (en) 1986-10-22
GB2173801A (en) 1986-10-22
DK182386A (da) 1986-10-23
ZA862987B (en) 1987-12-30
CN86102077A (zh) 1987-01-28
PT82435B (pt) 1988-08-17
GR861064B (en) 1986-09-01
KR860008191A (ko) 1986-11-12
CH667273A5 (de) 1988-09-30
PT82435A (en) 1986-05-01
YU65886A (en) 1988-04-30
CA1302426C (fr) 1992-06-02
AU599022B2 (en) 1990-07-12
HUT41040A (en) 1987-03-30
MY102926A (en) 1993-03-31
LU86401A1 (fr) 1986-11-05

Similar Documents

Publication Publication Date Title
OA08370A (fr) Agents antiparasitaires et leur procédé de préparation.
DZ418A1 (fr) Dérivés de céphalosporine, leur procédé de préparation et leur application thérapeutique.
OA08235A (fr) Composés intermediaires de carbapénem et leur procédé de préparation.
FR2707641B1 (fr) Composés de l'imidazol-5-carboxamide, leur procédé de préparation leurs intermédiaires et leur utilisation en thérapeutique.
GR861764B (en) Process for the preparation of phenylethanolamino-tetralines having lypolytic activity
PT83643B (pt) Processo de preparacao de derivados de quinoleina
PH22399A (en) Process for the preparation of certain pairs of enantiomers of (-cyano-3-phenoxy-4-fluorobenzyl peremethrate
DZ701A1 (fr) Nouveaux dérivés de la vinyl-6, furo-(3,4-c)-pyridine ainsi que leur procédé de préparation.
DZ702A1 (fr) Nouveaux dérivés de la carboxymethoxy-7 furo-(3,4-c)-pyridine ainsi que leur procédé de préparation.
NO175299C (no) Fremgangsmåte for kontinuerlig raffinering av silisium
GB8527809D0 (en) Process for preparation of silibinin
OA06951A (fr) Dérivés de la thiéno-pyridinone, leur procédé de préparation et leur application thérapeutique.
OA06201A (fr) Procédé de préparation de nouveaux composés d'urée et amido .
OA07984A (fr) Procédé stéréocontrolé de préparation d'acetoxyazetidione.
OA07674A (fr) Procédé de préparation de dérivés de carbapénem, nouveaux intermédiaires de synthèse et préparation de ces intermédiaires.
FR2355020A1 (fr) Antibiotiques de b-lactames et leur procede de preparation
PT84624B (pt) Processo de preparacao de imidazois substituidos
DZ850A1 (fr) Nouveaux dérivés de la phénéthylaminoalcoyle-6 furo-(3,4-c)-pyridine et leur procédé de préparation.
BR8700509A (pt) Processo de fabricacao em fase gasosa do cloropentafluretano
FI863282A0 (fi) Uusi menetelmä valmistaa metyleenidioksifenantreeniyhdisteitä
OA06451A (fr) Procédé de préparation de composés B-lactame.
DZ851A1 (fr) Nouveaux dérivés de la pyridine et leur procédé depréparation.
FR2566776B1 (fr) Procede de preparation de metalloporphyrines
DZ779A1 (fr) Nouveaux dérivés de la quinoléine ainse que leur procédé de préparation.
FR2557877B1 (fr) Procede de preparation d'alcaloides dimeres