DK1815028T3 - Mikrobobler til affinitetsseparation - Google Patents
Mikrobobler til affinitetsseparationInfo
- Publication number
- DK1815028T3 DK1815028T3 DK05858304.8T DK05858304T DK1815028T3 DK 1815028 T3 DK1815028 T3 DK 1815028T3 DK 05858304 T DK05858304 T DK 05858304T DK 1815028 T3 DK1815028 T3 DK 1815028T3
- Authority
- DK
- Denmark
- Prior art keywords
- microbubbles
- affinity
- affinity separation
- methods
- coated
- Prior art date
Links
- 238000000926 separation method Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 238000001261 affinity purification Methods 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 239000011521 glass Substances 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
- G01N33/545—Synthetic resin
- G01N33/546—Synthetic resin as water suspendable particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
- G01N33/545—Synthetic resin
- G01N33/547—Synthetic resin with antigen or antibody attached to the carrier via a bridging agent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
- G01N33/552—Glass or silica
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/76—Assays involving albumins other than in routine use for blocking surfaces or for anchoring haptens during immunisation
- G01N2333/765—Serum albumin, e.g. HSA
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Inorganic Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62494804P | 2004-11-03 | 2004-11-03 | |
| PCT/US2005/040162 WO2006137933A2 (en) | 2004-11-03 | 2005-11-03 | Microbubbles for affinity separation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1815028T3 true DK1815028T3 (da) | 2012-01-30 |
Family
ID=37570908
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05858304.8T DK1815028T3 (da) | 2004-11-03 | 2005-11-03 | Mikrobobler til affinitetsseparation |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US8835186B2 (https=) |
| EP (2) | EP2302078B1 (https=) |
| JP (2) | JP5037350B2 (https=) |
| KR (1) | KR101281433B1 (https=) |
| CN (2) | CN103091485A (https=) |
| AT (1) | ATE530666T1 (https=) |
| AU (1) | AU2005333157B2 (https=) |
| CA (1) | CA2585675A1 (https=) |
| DK (1) | DK1815028T3 (https=) |
| ES (2) | ES2376578T3 (https=) |
| PT (1) | PT1815028E (https=) |
| WO (1) | WO2006137933A2 (https=) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103091485A (zh) | 2004-11-03 | 2013-05-08 | 艾瑞斯国际有限公司 | 用于亲和分离的微泡 |
| DE602005023529D1 (de) | 2004-11-03 | 2010-10-21 | Iris Molecular Diagnostics Inc | Homogener nachweis von analyten |
| WO2012161226A1 (ja) * | 2011-05-23 | 2012-11-29 | 積水メディカル株式会社 | Pivka-ii測定試薬における非特異反応の抑制方法 |
| WO2013096157A1 (en) * | 2011-12-21 | 2013-06-27 | 3M Innovative Properties Company | Bioseparation compositions and methods for making and using same |
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| US20140288421A1 (en) * | 2013-03-12 | 2014-09-25 | The Regents Of The University Of California | Gas vesicle ultrasound contrast agents and methods of using the same |
| EP3933384A1 (en) | 2013-03-15 | 2022-01-05 | Hycor Biomedical, LLC | Device and associated method for performing luminescence and fluorescence measurements of a sample |
| WO2015198153A2 (en) * | 2014-01-28 | 2015-12-30 | Targeson, Inc. | Isolation of cells and biological substances using buoyant microbubbles |
| JP6557681B2 (ja) * | 2014-05-10 | 2019-08-07 | ダイアグノロジックス・エルエルシー | 浮力を用いて薬剤を単離または濃縮するためのシステムおよび装置 |
| US11291931B2 (en) * | 2014-12-15 | 2022-04-05 | Akadeum Life Sciences, Inc. | Method and system for buoyant separation |
| WO2016100290A1 (en) | 2014-12-15 | 2016-06-23 | Akadeum Life Sciences, LLC | Method and system for buoyant separation |
| JP6716683B2 (ja) | 2015-05-01 | 2020-07-01 | バイオレジェンド,インコーポレイテッド | 安定なナノ磁性粒子分散 |
| CN108780081B (zh) | 2015-08-10 | 2021-04-09 | Essenlix公司 | 步骤简化、小样品、快速、易使用的生物/化学分析装置和方法 |
| HK1250543A1 (zh) | 2015-08-24 | 2018-12-21 | 日本瑞翁株式会社 | 用於多步骤细胞纯化和浓缩的方法和装置 |
| US10976232B2 (en) | 2015-08-24 | 2021-04-13 | Gpb Scientific, Inc. | Methods and devices for multi-step cell purification and concentration |
| WO2017048871A1 (en) | 2015-09-14 | 2017-03-23 | Essenlix Corp. | Device and system for analyzing a sample, particularly blood, as well as methods of using the same |
| CN111426822B (zh) | 2015-09-14 | 2022-12-13 | 艾森利克斯公司 | 采集分析蒸汽凝析,特别是呼出气凝析的装置与系统,以及使用方法 |
| EP3892316A3 (en) * | 2015-12-29 | 2021-11-24 | Thermogenesis Corp. | Cell separation devices, systems, and methods |
| WO2017190117A1 (en) * | 2016-04-30 | 2017-11-02 | BioLegend, Inc. | Compositions and methods for performing magnetibuoyant separations |
| KR102381114B1 (ko) * | 2016-10-06 | 2022-03-30 | 아이리스 인터내셔널 인크. | 동적 포커스 시스템 및 방법들 |
| WO2018112262A2 (en) | 2016-12-16 | 2018-06-21 | Diagnologix, Llc | Buoyancy enabled separation method and system |
| US10628693B2 (en) | 2016-12-21 | 2020-04-21 | Essenlix Corporation | Devices and methods for authenticating a sample and use of the same |
| WO2018148342A1 (en) | 2017-02-07 | 2018-08-16 | Essenlix Corporation | Compressed open flow assay and use |
| US11927560B2 (en) | 2017-02-08 | 2024-03-12 | Essenlix Corporation | Bio/chemical material extraction and assay |
| CA3052809A1 (en) | 2017-02-08 | 2018-08-23 | Essenlix Corporation | Qmax assays and applications |
| CN111656155B (zh) | 2017-02-08 | 2024-05-31 | 上海宜晟生物科技有限公司 | 用于延迟分析的样品采集和操作 |
| CN110998324B (zh) | 2017-02-08 | 2025-03-28 | 上海宜晟生物科技有限公司 | 数字测定 |
| US12151246B2 (en) | 2017-02-08 | 2024-11-26 | Essenlix Corporation | Molecular manipulation and assay with controlled temperature |
| CN111433606B (zh) | 2017-02-09 | 2024-05-24 | 上海宜晟生物科技有限公司 | 采用不同间距高度的测定 |
| CN110998325B (zh) | 2017-02-09 | 2024-08-16 | 上海宜晟生物科技有限公司 | 扩增测定 |
| EP3662259A4 (en) | 2017-02-09 | 2021-08-25 | Essenlix Corporation | COLORIMETRIC TESTS |
| JP2020508043A (ja) | 2017-02-15 | 2020-03-19 | エッセンリックス コーポレーション | 急速な温度変化を伴うアッセイ |
| US11523752B2 (en) | 2017-02-16 | 2022-12-13 | Essenlix Corporation | Assay for vapor condensates |
| EP3638421A4 (en) | 2017-06-12 | 2021-04-07 | Essenlix Corporation | HOMOGENOUS ASSAY |
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| WO2019028123A1 (en) | 2017-08-01 | 2019-02-07 | Essenlix Corporation | COLLECTION, MAINTENANCE AND DETERMINATION OF SAMPLES |
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| WO2019075415A1 (en) | 2017-10-13 | 2019-04-18 | Essenlix Corporation | DEVICES AND METHODS FOR AUTHENTICATING MEDICAL ANALYSIS AND USES THEREOF |
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| US11609224B2 (en) | 2017-10-26 | 2023-03-21 | Essenlix Corporation | Devices and methods for white blood cell analyses |
| US11648551B2 (en) | 2017-12-12 | 2023-05-16 | Essenlix Corporation | Sample manipulation and assay with rapid temperature change |
| CN112534259A (zh) | 2017-12-14 | 2021-03-19 | Essenlix公司 | 监测毛发的装置,系统和方法 |
| WO2019140334A1 (en) | 2018-01-11 | 2019-07-18 | Essenlix Corporation | Homogeneous assay (ii) |
| CN111902720B (zh) | 2018-03-21 | 2025-02-07 | 沃特世科技公司 | 基于非抗体高亲和力的样品制备、吸附剂、装置和方法 |
| US11350909B2 (en) | 2018-04-17 | 2022-06-07 | California Institute Of Technology | Cross amplitude modulation ultrasound pulse sequence |
| WO2020014273A1 (en) | 2018-07-09 | 2020-01-16 | Akadeum Life Sciences, Inc. | System and method for buoyant particle processing |
| US11885952B2 (en) | 2018-07-30 | 2024-01-30 | Essenlix Corporation | Optics, device, and system for assaying and imaging |
| CN109608679B (zh) * | 2018-12-10 | 2021-09-21 | 天津工业大学 | 一种核孔复合体接枝聚合物仿生膜制备方法 |
| CN110354523B (zh) * | 2019-07-14 | 2024-02-06 | 河北龙亿环境工程有限公司 | 一种具有多微孔气泡罩的新型塔板 |
| WO2021059195A1 (en) * | 2019-09-26 | 2021-04-01 | 3M Innovative Properties Company | Compositions and methods of detecting analytes |
| EP4392158A4 (en) | 2021-08-26 | 2025-09-03 | Akadeum Life Sciences Inc | METHOD AND SYSTEM FOR FLOATING SEPARATION |
| US20240368579A1 (en) * | 2021-09-07 | 2024-11-07 | Triangle Biotechnology, Inc. | Targeted nanodroplet and microbubble compositions and methods for enrichment, lysis, and extraction of microbial cells |
| US12196754B2 (en) | 2022-04-01 | 2025-01-14 | Akadeum Life Sciences, Inc. | Method and system for buoyant-particle-assisted cell therapy |
| JP2026511329A (ja) | 2023-02-14 | 2026-04-14 | アカデューム ライフ サイエンセズ,インコーポレイテッド | 部分的または完全に自動化された浮力補助分離方法およびシステム |
Family Cites Families (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1582956A (en) * | 1976-07-30 | 1981-01-21 | Ici Ltd | Composite magnetic particles |
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| DE3100535A1 (de) | 1981-01-10 | 1982-08-12 | Dr. Karl Thomae Gmbh, 7950 Biberach | "neue carbonsaeure-derivate, ihre herstellung und ihre verwendung als arzneimittel" |
| FR2571498B1 (fr) * | 1984-10-04 | 1988-04-08 | Immunotech Sa | Procede de separation de cellules utilisant des anticorps et des billes de faible densite |
| US4618525A (en) * | 1985-06-03 | 1986-10-21 | Minnesota Mining And Manufacturing Company | Coated glass microbubbles and article incorporating them |
| US4824776A (en) * | 1985-07-25 | 1989-04-25 | Molecular Biosystems, Inc. | Method for increasing the sensitivity of nucleic acid hybridization assays |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US4933447A (en) * | 1987-09-24 | 1990-06-12 | Ss Pharmaceutical Co., Ltd. | Quinoline derivatives |
| US4957656A (en) | 1988-09-14 | 1990-09-18 | Molecular Biosystems, Inc. | Continuous sonication method for preparing protein encapsulated microbubbles |
| US5766849A (en) * | 1989-07-11 | 1998-06-16 | Gen-Probe Incorporated | Methods of amplifying nucleic acids using promoter-containing primer sequence |
| WO1993007883A1 (en) | 1991-10-24 | 1993-04-29 | Isis Pharmaceuticals, Inc. | Derivatized oligonucleotides having improved uptake and other properties |
| SE9002480D0 (sv) * | 1990-07-23 | 1990-07-23 | Hans Lilja | Assay of free and complexed prostate-specific antigen |
| EP0488152A3 (en) | 1990-11-30 | 1992-11-25 | Hitachi, Ltd. | Method for immunoassay and apparatus therefor |
| EP0529070A1 (en) * | 1991-02-27 | 1993-03-03 | Amoco Corporation | Methods for improving the sensitivity of hybridization assays |
| IE920778A1 (en) | 1991-03-12 | 1992-09-23 | Du Pont | Method for specific binding assays using a releasable ligand |
| US5665539A (en) * | 1991-07-12 | 1997-09-09 | The Regents Of The University Of California | Immuno-polymerase chain reaction system for antigen detection |
| US6723303B1 (en) * | 1991-09-17 | 2004-04-20 | Amersham Health, As | Ultrasound contrast agents including protein stabilized microspheres of perfluoropropane, perfluorobutane or perfluoropentane |
| US5270184A (en) * | 1991-11-19 | 1993-12-14 | Becton, Dickinson And Company | Nucleic acid target generation |
| US6172208B1 (en) * | 1992-07-06 | 2001-01-09 | Genzyme Corporation | Oligonucleotides modified with conjugate groups |
| DE4232755A1 (de) | 1992-09-26 | 1994-03-31 | Schering Ag | Mikropartikelpräparationen aus biologisch abbaubaren Mischpolymeren |
| EP0688366B1 (en) * | 1993-01-15 | 2002-05-22 | The Public Health Research Institute Of The City Of New York, Inc. | Sensitive nucleic acid sandwich hybridization assays and kits |
| US5985548A (en) * | 1993-02-04 | 1999-11-16 | E. I. Du Pont De Nemours And Company | Amplification of assay reporters by nucleic acid replication |
| ATE244406T1 (de) * | 1993-05-10 | 2003-07-15 | Nissui Pharm Co Ltd | Verfahren zur bestimmung von mehr als einem immunologischen liganden und bestimmungsreagenz sowie satz dafuer |
| US5635602A (en) * | 1993-08-13 | 1997-06-03 | The Regents Of The University Of California | Design and synthesis of bispecific DNA-antibody conjugates |
| US5599677A (en) * | 1993-12-29 | 1997-02-04 | Abbott Laboratories | Immunoassays for prostate specific antigen |
| US5648213A (en) * | 1994-08-30 | 1997-07-15 | Beckman Instruments, Inc. | Compositions and methods for use in detection of analytes |
| JPH08178926A (ja) * | 1994-10-25 | 1996-07-12 | Sumitomo Pharmaceut Co Ltd | イムノアッセイプレートおよびその用途 |
| BR9509673A (pt) | 1994-11-15 | 1997-09-30 | Upjohn Co | Compostos e uso dos mesmos |
| SE504798C2 (sv) | 1995-06-16 | 1997-04-28 | Ulf Landegren | Immunanalys och testkit med två reagens som kan tvärbindas om de adsorberats till analyten |
| DE19524133A1 (de) * | 1995-07-03 | 1997-01-09 | Bayer Ag | Die Verwendung von neuen und bekannten kationischen 4,5-Dihydro-1H-1,2,3-triazoliumverbindungen als Farbstoffe, neue kationische 4,5-Dihydro-1H-1,2,3-triazoliumverbindungen und deren Herstellung |
| NO301198B1 (no) | 1995-07-14 | 1997-09-22 | Alcatel Kabel Norge As | Kabel, fremgangsmåte og impregneringsmasse |
| AT403803B (de) | 1996-04-19 | 1998-05-25 | Sanochemia Ltd | Neue benzazepinderivate, diese enthaltende arzneimittel und verwendung derselben zum herstellen von arzneimitteln |
| US6165942A (en) | 1996-10-03 | 2000-12-26 | Nissan Chemical Industries, Ltd. | Heterocycle-fused pyrimidinone derivative and herbicidal composition |
| US6083484A (en) * | 1996-10-17 | 2000-07-04 | Molecular Biosystems, Inc. | Microparticles stabilized by polynuclear chromium complexes and their use as ultrasound contrast agents |
| US6245318B1 (en) | 1997-05-27 | 2001-06-12 | Mallinckrodt Inc. | Selectively binding ultrasound contrast agents |
| US6086540A (en) * | 1997-10-07 | 2000-07-11 | Molecular Biosystems, Inc. | Methods of ultrasound imaging using echogenically persistent contrast agents |
| US6531278B1 (en) * | 1998-01-14 | 2003-03-11 | Utah State University | Ligand-DNA composition for capture and detection of contaminants on a solid surface |
| EP1073716B1 (en) * | 1998-04-28 | 2004-04-28 | Amersham Health AS | Improvements in or relating to separation processes |
| US8063190B2 (en) * | 1998-06-02 | 2011-11-22 | Tom Robin Caine Boyde | Nucleic acid-linked conjugates and methods for making and using them |
| US6214566B1 (en) * | 1998-11-16 | 2001-04-10 | The Administrators Of The Tulane Educational Fund | Method for detecting anti-squalene antibodies |
| AU2410500A (en) | 1999-01-11 | 2000-08-01 | President And Fellows Of Harvard College | Isothermal amplification of dna |
| ATE312350T1 (de) * | 1999-10-13 | 2005-12-15 | Univ British Columbia | Verfahren zur identifizierung von verbindungen, die die neuronale aktivität modulieren |
| CA2391534A1 (en) * | 1999-11-15 | 2001-05-25 | Drug Innovation & Design, Inc. | Selective cellular targeting: multifunctional delivery vehicles |
| US7306904B2 (en) * | 2000-02-18 | 2007-12-11 | Olink Ab | Methods and kits for proximity probing |
| US6511809B2 (en) * | 2000-06-13 | 2003-01-28 | E. I. Du Pont De Nemours And Company | Method for the detection of an analyte by means of a nucleic acid reporter |
| US7439016B1 (en) | 2000-06-15 | 2008-10-21 | Digene Corporation | Detection of nucleic acids by type-specific hybrid capture method |
| WO2002068695A2 (en) | 2001-02-22 | 2002-09-06 | Arcturus Engineering, Inc. | Quantitative immunohistochemistry (qihc) |
| WO2002083951A1 (en) | 2001-04-10 | 2002-10-24 | Northeastern University | Multiplexed ligand/protein binding assays with pna labels |
| EP1249500A1 (de) | 2001-04-12 | 2002-10-16 | chimera biotec GmbH | Verfahren zum Nachweis einer Substanz |
| WO2003011824A1 (en) | 2001-07-31 | 2003-02-13 | Bristol-Myers Squibb Company | Bicyclic modulators of androgen receptor function |
| CA2478203C (en) | 2002-03-08 | 2011-06-14 | Eidgenossische Technische Hochschule Zurich | Encoded self-assembling chemical libraries (esachel) |
| NZ537277A (en) * | 2002-07-18 | 2008-04-30 | Crucell Holland Bv | Recombinant production of mixtures of antibodies |
| BR0313405A (pt) | 2002-08-12 | 2005-07-12 | Takeda Pharmaceutical | Compostos, métodos para preparar um composto e para prevenir e/ou tratar câncer, prodroga, medicamento, modulador do receptor de androgênio, agente para prevenir e/ou tratar hipogonadismo ou pertubação climatérica masculina, osteoporose e câncer, e, uso de um composto |
| EP2290100B1 (en) | 2002-11-01 | 2014-02-19 | Iris International, Inc. | Kits for displacement Sandwich Immuno-PCR |
| WO2006012356A2 (en) * | 2004-06-23 | 2006-02-02 | Washington University | Methods for determining risk of developing regular smoking behavior |
| AU2005286648A1 (en) | 2004-09-20 | 2006-03-30 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors |
| CN103091485A (zh) | 2004-11-03 | 2013-05-08 | 艾瑞斯国际有限公司 | 用于亲和分离的微泡 |
| DE602005023529D1 (de) * | 2004-11-03 | 2010-10-21 | Iris Molecular Diagnostics Inc | Homogener nachweis von analyten |
| CN103884840A (zh) * | 2008-02-21 | 2014-06-25 | 艾瑞斯国际有限公司 | 早期确定前列腺癌治疗后复发的方法 |
-
2005
- 2005-11-03 CN CN2012103784026A patent/CN103091485A/zh active Pending
- 2005-11-03 AU AU2005333157A patent/AU2005333157B2/en not_active Ceased
- 2005-11-03 ES ES05858304T patent/ES2376578T3/es not_active Expired - Lifetime
- 2005-11-03 JP JP2007539371A patent/JP5037350B2/ja not_active Expired - Fee Related
- 2005-11-03 CA CA002585675A patent/CA2585675A1/en not_active Abandoned
- 2005-11-03 CN CN2005800380828A patent/CN101065497B/zh not_active Expired - Fee Related
- 2005-11-03 AT AT05858304T patent/ATE530666T1/de active
- 2005-11-03 US US11/718,090 patent/US8835186B2/en not_active Expired - Fee Related
- 2005-11-03 WO PCT/US2005/040162 patent/WO2006137933A2/en not_active Ceased
- 2005-11-03 EP EP10190637.8A patent/EP2302078B1/en not_active Expired - Lifetime
- 2005-11-03 ES ES10190637.8T patent/ES2550177T3/es not_active Expired - Lifetime
- 2005-11-03 EP EP05858304A patent/EP1815028B1/en not_active Expired - Lifetime
- 2005-11-03 PT PT05858304T patent/PT1815028E/pt unknown
- 2005-11-03 DK DK05858304.8T patent/DK1815028T3/da active
- 2005-11-03 KR KR1020077012524A patent/KR101281433B1/ko not_active Expired - Fee Related
-
2011
- 2011-05-31 US US13/149,551 patent/US8513032B2/en not_active Expired - Fee Related
- 2011-05-31 US US13/149,586 patent/US20110236884A1/en not_active Abandoned
-
2012
- 2012-05-17 JP JP2012113421A patent/JP2012197281A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2012197281A (ja) | 2012-10-18 |
| CN101065497B (zh) | 2012-11-21 |
| EP2302078A1 (en) | 2011-03-30 |
| ATE530666T1 (de) | 2011-11-15 |
| CA2585675A1 (en) | 2006-12-28 |
| ES2550177T3 (es) | 2015-11-05 |
| EP2302078B1 (en) | 2015-07-15 |
| EP1815028A4 (en) | 2008-09-10 |
| ES2376578T3 (es) | 2012-03-15 |
| AU2005333157B2 (en) | 2011-06-30 |
| JP5037350B2 (ja) | 2012-09-26 |
| US20110230644A1 (en) | 2011-09-22 |
| AU2005333157A1 (en) | 2006-12-28 |
| US8835186B2 (en) | 2014-09-16 |
| KR20070110484A (ko) | 2007-11-19 |
| WO2006137933A2 (en) | 2006-12-28 |
| KR101281433B1 (ko) | 2013-07-02 |
| EP1815028A2 (en) | 2007-08-08 |
| US20110236884A1 (en) | 2011-09-29 |
| US20090176201A1 (en) | 2009-07-09 |
| CN103091485A (zh) | 2013-05-08 |
| CN101065497A (zh) | 2007-10-31 |
| US8513032B2 (en) | 2013-08-20 |
| PT1815028E (pt) | 2012-01-24 |
| WO2006137933A3 (en) | 2007-05-03 |
| EP1815028B1 (en) | 2011-10-26 |
| JP2008518973A (ja) | 2008-06-05 |
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