WO2005044849A3 - Lp mammalian proteins; related reagents - Google Patents

Lp mammalian proteins; related reagents Download PDF

Info

Publication number
WO2005044849A3
WO2005044849A3 PCT/US2004/019099 US2004019099W WO2005044849A3 WO 2005044849 A3 WO2005044849 A3 WO 2005044849A3 US 2004019099 W US2004019099 W US 2004019099W WO 2005044849 A3 WO2005044849 A3 WO 2005044849A3
Authority
WO
WIPO (PCT)
Prior art keywords
mammalian proteins
related reagents
reagents
mammalian
proteins
Prior art date
Application number
PCT/US2004/019099
Other languages
French (fr)
Other versions
WO2005044849A2 (en
Inventor
Jai Pal Singh
Asavari Prasad Wagle
Original Assignee
Lilly Co Eli
Jai Pal Singh
Asavari Prasad Wagle
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli, Jai Pal Singh, Asavari Prasad Wagle filed Critical Lilly Co Eli
Publication of WO2005044849A2 publication Critical patent/WO2005044849A2/en
Publication of WO2005044849A3 publication Critical patent/WO2005044849A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6437—Coagulation factor VIIa (3.4.21.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21021—Coagulation factor VIIa (3.4.21.21)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Isolated and/or recombinant compositions related to Factor VIIa, reagents related thereto are provided. Methods of using said reagents and diagnostic kits are also provided.
PCT/US2004/019099 2003-08-05 2004-07-22 Lp mammalian proteins; related reagents WO2005044849A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49249903P 2003-08-05 2003-08-05
US60/492,499 2003-08-05

Publications (2)

Publication Number Publication Date
WO2005044849A2 WO2005044849A2 (en) 2005-05-19
WO2005044849A3 true WO2005044849A3 (en) 2005-08-04

Family

ID=34572730

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/019099 WO2005044849A2 (en) 2003-08-05 2004-07-22 Lp mammalian proteins; related reagents

Country Status (1)

Country Link
WO (1) WO2005044849A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101652387A (en) 2006-11-02 2010-02-17 阿塞勒隆制药公司 Alk1 receptor and ligand antagonists and uses thereof
US8642031B2 (en) 2006-11-02 2014-02-04 Acceleron Pharma, Inc. Antagonists of BMP9, BMP10, ALK1 and other ALK1 ligands, and uses thereof
US10059756B2 (en) 2006-11-02 2018-08-28 Acceleron Pharma Inc. Compositions comprising ALK1-ECD protein
CN102099374B (en) 2008-05-02 2016-06-08 阿塞勒隆制药公司 For regulating the method and composition based on ALK1 antagonist that blood vessel occurs and pericyte wraps up

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0200421A2 (en) * 1985-04-17 1986-11-05 Zymogenetics, Inc. Expression of factor VII activity in mammalian cells

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0200421A2 (en) * 1985-04-17 1986-11-05 Zymogenetics, Inc. Expression of factor VII activity in mammalian cells

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
NICOLAISEN E M: "GENERATION OF GLA-DOMAINLESS FVIIA BY CATHEPSIN G-MEDIATED CLEAVAGE", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 306, no. 2 / 3, 20 July 1992 (1992-07-20), pages 157 - 160, XP000286918, ISSN: 0014-5793 *
PERSSON E ET PETERSON L C: "Structurally and functionally distinct Ca2+ binding sites in the gamma-carboxyglutamic acid-containing domain of factor VIIa", EUROPEAN JOURNAL OF BIOCHEMISTRY, BERLIN, DE, vol. 234, no. 1, 15 November 1995 (1995-11-15), pages 293 - 300, XP002101115, ISSN: 0014-2956 *

Also Published As

Publication number Publication date
WO2005044849A2 (en) 2005-05-19

Similar Documents

Publication Publication Date Title
WO2006137933A3 (en) Microbubbles for affinity separation
WO2005010049A3 (en) Tgf-beta1 ligands
WO2005107491A3 (en) Multi-lectin affinity chromatography and uses thereof
WO2006119107A3 (en) Sclerostin binding agents
WO2006119062A3 (en) Sclerostin epitopes
AU2002235994A1 (en) Method for producing proteins by fermentation of microorganisms from the thermus family, the protein mixture thus obtained and cosmetic compositions containing same
NO20020809L (en) Isomeric bonded pyrrolocarbazoles and isoindolines
WO2006122825A3 (en) Single domain vhh antibodies against von willebrand factor
WO2002020569A3 (en) Mammalian genes; related reagents and methods
AU2002359522A1 (en) Compositions and methods of selective nucleic acid isolation
WO2001075087A3 (en) Subtilisin variants
WO2006017538A3 (en) Hk1-binding proteins
WO2001064920A3 (en) Hybrid expression of neisserial proteins
WO2002006457A3 (en) Novel lipase genes
NO20030495L (en) Peptides presented by cells
WO2004011605A3 (en) Hybrid protein methods and compositions
WO2006116498A3 (en) Purified form of tanaproget
WO2004081033A3 (en) Synthesis of proteins by cell-free protein expression
WO2005044849A3 (en) Lp mammalian proteins; related reagents
WO2003020005A3 (en) Lp mammalian proteins; related reagents
WO2002074906A3 (en) Lp mammalian proteins; related reagents
WO2002068596A3 (en) Mammalian cytokines; related reagents
WO2005065711A3 (en) Mammalian receptor proteins; related reagents and methods
WO2002063009A8 (en) Lp mammalian proteins; related reagents
WO2002074921A3 (en) Methods for isolating proteins expressed by dendritic cells

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase