DK1802302T3 - Ny anvendelse af alfa-sympatomiketika med 2-imidazolinstruktur - Google Patents
Ny anvendelse af alfa-sympatomiketika med 2-imidazolinstruktur Download PDFInfo
- Publication number
- DK1802302T3 DK1802302T3 DK05784163.7T DK05784163T DK1802302T3 DK 1802302 T3 DK1802302 T3 DK 1802302T3 DK 05784163 T DK05784163 T DK 05784163T DK 1802302 T3 DK1802302 T3 DK 1802302T3
- Authority
- DK
- Denmark
- Prior art keywords
- oxymetazoline
- xylometazoline
- acid
- medicament
- compounds
- Prior art date
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- WYWIFABBXFUGLM-UHFFFAOYSA-N oxymetazoline Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C)=C1CC1=NCCN1 WYWIFABBXFUGLM-UHFFFAOYSA-N 0.000 claims description 56
- HUCJFAOMUPXHDK-UHFFFAOYSA-N Xylometazoline Chemical compound CC1=CC(C(C)(C)C)=CC(C)=C1CC1=NCCN1 HUCJFAOMUPXHDK-UHFFFAOYSA-N 0.000 claims description 46
- 229960001528 oxymetazoline Drugs 0.000 claims description 28
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Claims (6)
1. Oxymetazolin og/eller xylometazolin til anvendelse til antiviral profylakse og/eller antiviral behandling af virussygdomme valgt fra gruppen bestående af akut rhinitis, influenza, parainfluenza, otitis media og sinusitis, hvor oxymetazolin og/eller xylometazolin har antiviral aktivitet.
2. Forbindelser til anvendelse ifølge krav 1, kendetegnet ved at medikamentet er beregnet til topisk anvendelse.
3. Forbindelser til anvendelse ifølge krav 2, kendetegnet ved at medikamentet er beregnet til anvendelse på slimhindemembranerne.
4. Forbindelser til anvendelse ifølge et eller flere af kravene 1 til 3, kendetegnet ved at oxymetazolin og/eller xylometazolin er til stede i en vandig opløsning.
5. Forbindelser til anvendelse ifølge krav 4, kendetegnet ved at den vandige opløsning indeholder mindst én buffer, fortrinsvis phosphat- eller citratbuffer.
6. Forbindelser til anvendelse ifølge krav 4 og/eller 5, kendetegnet ved at den vandige opløsning indeholder mindst ét konserveringsmiddel, fortrinsvis benzalkoniumchlorid.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004049008A DE102004049008A1 (de) | 2004-10-05 | 2004-10-05 | Neue Verwendung für α-Sympathomimetika mit 2-Imidazolinstruktur |
| PCT/EP2005/010026 WO2006037452A1 (de) | 2004-10-05 | 2005-09-16 | NEUE VERWENDUNG FÜR α-SYMPATHOMIMETIKA MIT 2-IMIDAZOLINSTRUKTUR |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1802302T3 true DK1802302T3 (da) | 2017-02-06 |
Family
ID=35276675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05784163.7T DK1802302T3 (da) | 2004-10-05 | 2005-09-16 | Ny anvendelse af alfa-sympatomiketika med 2-imidazolinstruktur |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20080108685A1 (da) |
| EP (1) | EP1802302B1 (da) |
| JP (1) | JP5311825B2 (da) |
| KR (1) | KR20070059134A (da) |
| CN (1) | CN101022797B (da) |
| AU (1) | AU2005291603B2 (da) |
| BR (1) | BRPI0516832A (da) |
| CA (1) | CA2582984C (da) |
| CY (1) | CY1118581T1 (da) |
| DE (1) | DE102004049008A1 (da) |
| DK (1) | DK1802302T3 (da) |
| ES (1) | ES2612544T3 (da) |
| HU (1) | HUE031515T2 (da) |
| LT (1) | LT1802302T (da) |
| MX (1) | MX2007004040A (da) |
| PL (1) | PL1802302T3 (da) |
| PT (1) | PT1802302T (da) |
| RU (1) | RU2397764C2 (da) |
| WO (1) | WO2006037452A1 (da) |
| ZA (1) | ZA200703622B (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004049008A1 (de) | 2004-10-05 | 2006-04-06 | Merck Patent Gmbh | Neue Verwendung für α-Sympathomimetika mit 2-Imidazolinstruktur |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69229880T2 (de) | 1991-11-19 | 2000-05-04 | Univ Virginia | Kombinierte virustatikum-antimediator-behandlung (covam) von gewöhnlichen erkältungen |
| JPH06211659A (ja) | 1993-01-19 | 1994-08-02 | Kowa Co | 点鼻薬組成物 |
| US5576437A (en) | 1993-12-17 | 1996-11-19 | The Procter & Gamble Company | 7-(2-imidazolnylamino) quinoline compounds useful as alpha-2 adrenoceptor agonists |
| DE4438589A1 (de) | 1994-10-28 | 1995-03-23 | Reingard Dr Muenster | Nasentherapeutikum |
| WO1996025163A1 (en) * | 1995-02-14 | 1996-08-22 | Board Of Supervisors Or Louisiana State Universityof Agricultural And Mechanical College Through Itsmedical Center | Treatment of herpes simplex viruses |
| US5916900A (en) * | 1995-06-29 | 1999-06-29 | The Procter & Gamble Company | 7-(2-imidazolinylamino)quinoline compounds useful as alpha-2 adrenoceptor agonists |
| DE19541919C2 (de) | 1995-11-10 | 1997-11-20 | Klosterfrau Mcm Vetrieb Gmbh | Pharmazeutische Zubereitung zur Behandlung akuter Rhinitiden |
| EP0903151A1 (en) | 1997-09-22 | 1999-03-24 | ASTA Medica Aktiengesellschaft | Use of combinations comprising non-sedating antihistamines and alpha-adrenergic drugs for the topical treatment of rhinitis/conjunctivitis and cold, cold-like and/or flu symptoms |
| JP2004509920A (ja) | 2000-09-29 | 2004-04-02 | ボード オブ トラスティーズ オペレーティング ミシガン ステート ユニヴァーシティ | カテコールアミン医薬組成物および方法 |
| US7652030B2 (en) | 2001-09-18 | 2010-01-26 | Nycomed Danmark Aps | Compositions for treatment of common cold |
| DE10250944B9 (de) | 2002-10-31 | 2004-09-16 | Cell Center Cologne Gmbh | Verwendung eines Stifts zur Applikation von Pflege- oder Wirkstoffen in die Nase |
| DE102004049008A1 (de) | 2004-10-05 | 2006-04-06 | Merck Patent Gmbh | Neue Verwendung für α-Sympathomimetika mit 2-Imidazolinstruktur |
-
2004
- 2004-10-05 DE DE102004049008A patent/DE102004049008A1/de not_active Withdrawn
-
2005
- 2005-09-16 LT LTEP05784163.7T patent/LT1802302T/lt unknown
- 2005-09-16 DK DK05784163.7T patent/DK1802302T3/da active
- 2005-09-16 KR KR1020077007693A patent/KR20070059134A/ko not_active Application Discontinuation
- 2005-09-16 JP JP2007535042A patent/JP5311825B2/ja not_active Expired - Fee Related
- 2005-09-16 HU HUE05784163A patent/HUE031515T2/en unknown
- 2005-09-16 US US11/664,610 patent/US20080108685A1/en not_active Abandoned
- 2005-09-16 PT PT57841637T patent/PT1802302T/pt unknown
- 2005-09-16 RU RU2007116719/15A patent/RU2397764C2/ru not_active IP Right Cessation
- 2005-09-16 EP EP05784163.7A patent/EP1802302B1/de active Active
- 2005-09-16 MX MX2007004040A patent/MX2007004040A/es active IP Right Grant
- 2005-09-16 ES ES05784163.7T patent/ES2612544T3/es active Active
- 2005-09-16 CA CA2582984A patent/CA2582984C/en not_active Expired - Fee Related
- 2005-09-16 CN CN200580031735XA patent/CN101022797B/zh active Active
- 2005-09-16 WO PCT/EP2005/010026 patent/WO2006037452A1/de active Application Filing
- 2005-09-16 PL PL05784163T patent/PL1802302T3/pl unknown
- 2005-09-16 BR BRPI0516832-5A patent/BRPI0516832A/pt not_active Application Discontinuation
- 2005-09-16 AU AU2005291603A patent/AU2005291603B2/en active Active
-
2007
- 2007-05-04 ZA ZA200703622A patent/ZA200703622B/xx unknown
-
2017
- 2017-01-26 CY CY20171100121T patent/CY1118581T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1802302A1 (de) | 2007-07-04 |
| BRPI0516832A (pt) | 2008-09-23 |
| AU2005291603A1 (en) | 2006-04-13 |
| KR20070059134A (ko) | 2007-06-11 |
| JP2008515824A (ja) | 2008-05-15 |
| PL1802302T3 (pl) | 2017-08-31 |
| HUE031515T2 (en) | 2017-07-28 |
| CA2582984C (en) | 2012-06-05 |
| EP1802302B1 (de) | 2016-10-26 |
| CN101022797B (zh) | 2010-12-15 |
| ES2612544T3 (es) | 2017-05-17 |
| PT1802302T (pt) | 2017-02-07 |
| RU2007116719A (ru) | 2008-11-20 |
| ZA200703622B (en) | 2008-08-27 |
| CA2582984A1 (en) | 2006-04-13 |
| CY1118581T1 (el) | 2017-07-12 |
| JP5311825B2 (ja) | 2013-10-09 |
| MX2007004040A (es) | 2007-05-24 |
| AU2005291603B2 (en) | 2010-10-14 |
| US20080108685A1 (en) | 2008-05-08 |
| WO2006037452A1 (de) | 2006-04-13 |
| CN101022797A (zh) | 2007-08-22 |
| DE102004049008A1 (de) | 2006-04-06 |
| LT1802302T (lt) | 2017-02-10 |
| RU2397764C2 (ru) | 2010-08-27 |
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