DK1777236T3 - MODIFIED SUCCARIDES WHICH IMPROVED WATER STABILITY FOR USE AS A MEDICINE - Google Patents

MODIFIED SUCCARIDES WHICH IMPROVED WATER STABILITY FOR USE AS A MEDICINE Download PDF

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Publication number
DK1777236T3
DK1777236T3 DK06076853.8T DK06076853T DK1777236T3 DK 1777236 T3 DK1777236 T3 DK 1777236T3 DK 06076853 T DK06076853 T DK 06076853T DK 1777236 T3 DK1777236 T3 DK 1777236T3
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DK
Denmark
Prior art keywords
saccharide
modified
capsular
group
alkyl
Prior art date
Application number
DK06076853.8T
Other languages
Danish (da)
English (en)
Inventor
P Novartis Vac And Diagnostics Srl Costantino
F Novartis Vac And Diagnostics Srl Berti
F Novartis Vac And Diagnostics Srl Norelli
A Novartis Vac And Diagnostics Srl Bartoloni
Original Assignee
Glaxosmithkline Biologicals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0207117A external-priority patent/GB0207117D0/en
Priority claimed from GB0220195A external-priority patent/GB0220195D0/en
Priority claimed from GB0229494A external-priority patent/GB0229494D0/en
Priority claimed from GB0230163A external-priority patent/GB0230163D0/en
Application filed by Glaxosmithkline Biologicals Sa filed Critical Glaxosmithkline Biologicals Sa
Application granted granted Critical
Publication of DK1777236T3 publication Critical patent/DK1777236T3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Polymers & Plastics (AREA)
  • Immunology (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
DK06076853.8T 2002-03-26 2003-03-26 MODIFIED SUCCARIDES WHICH IMPROVED WATER STABILITY FOR USE AS A MEDICINE DK1777236T3 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0207117A GB0207117D0 (en) 2002-03-26 2002-03-26 Modified saccharides having improved stability in water
GB0220195A GB0220195D0 (en) 2002-08-30 2002-08-30 Modified saccharides having improved stability in water
GB0229494A GB0229494D0 (en) 2002-12-18 2002-12-18 Modified saccharides having improved stability in water
GB0230163A GB0230163D0 (en) 2002-12-24 2002-12-24 Modified saccharides having improved stability in water
EP03712543A EP1490409B1 (en) 2002-03-26 2003-03-26 Modified saccharides having improved stability in water

Publications (1)

Publication Number Publication Date
DK1777236T3 true DK1777236T3 (en) 2017-02-27

Family

ID=28457825

Family Applications (2)

Application Number Title Priority Date Filing Date
DK06076853.8T DK1777236T3 (en) 2002-03-26 2003-03-26 MODIFIED SUCCARIDES WHICH IMPROVED WATER STABILITY FOR USE AS A MEDICINE
DK03712543T DK1490409T3 (da) 2002-03-26 2003-03-26 Modificerede saccharider med forbedret stabilitet i vand

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK03712543T DK1490409T3 (da) 2002-03-26 2003-03-26 Modificerede saccharider med forbedret stabilitet i vand

Country Status (14)

Country Link
EP (2) EP1777236B8 (cg-RX-API-DMAC7.html)
JP (2) JP2005526153A (cg-RX-API-DMAC7.html)
AT (1) ATE419278T1 (cg-RX-API-DMAC7.html)
BR (1) BR0308768A (cg-RX-API-DMAC7.html)
CA (1) CA2480389C (cg-RX-API-DMAC7.html)
CY (2) CY1108911T1 (cg-RX-API-DMAC7.html)
DE (1) DE60325565D1 (cg-RX-API-DMAC7.html)
DK (2) DK1777236T3 (cg-RX-API-DMAC7.html)
ES (2) ES2616180T3 (cg-RX-API-DMAC7.html)
HU (1) HUE030532T2 (cg-RX-API-DMAC7.html)
MX (1) MXPA04009339A (cg-RX-API-DMAC7.html)
NZ (1) NZ535968A (cg-RX-API-DMAC7.html)
PT (2) PT1777236T (cg-RX-API-DMAC7.html)
WO (1) WO2003080678A1 (cg-RX-API-DMAC7.html)

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GB0822634D0 (en) 2008-12-11 2009-01-21 Novartis Ag Meningitis vaccines
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EP3461496B1 (en) * 2009-06-22 2023-08-23 Wyeth LLC Compositions and methods for preparing staphylococcus aureus serotype 5 and 8 capsular polysaccharide conjugate immunogenic compositions
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JP2013502918A (ja) 2009-08-27 2013-01-31 ノバルティス アーゲー 髄膜炎菌ｆＨＢＰ配列を含むハイブリッドポリペプチド
CN102724988B (zh) 2009-09-30 2014-09-10 诺华股份有限公司 脑膜炎球菌fHBP多肽的表达
CA2779816A1 (en) 2009-10-27 2011-05-05 Novartis Ag Modified meningococcal fhbp polypeptides
WO2011161653A1 (en) 2010-06-25 2011-12-29 Novartis Ag Combinations of meningococcal factor h binding proteins
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BR112013022397A2 (pt) 2011-03-02 2017-09-26 Derek O’Hagan vacinas combinadas com doses menores de antígeno e/ou adjuvante
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SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
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MX369534B (es) 2013-09-08 2019-11-11 Pfizer Composiciones de neisseria meningitidis y sus metodos.
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US10407703B2 (en) * 2014-04-17 2019-09-10 Medizinische Hochschule Hannover Means and methods for producing Neisseria meningitidis capsular polysaccharides of low dispersity
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Also Published As

Publication number Publication date
CA2480389A1 (en) 2003-10-02
HUE030532T2 (en) 2017-05-29
WO2003080678A1 (en) 2003-10-02
ES2616180T3 (es) 2017-06-09
EP1777236B1 (en) 2016-11-30
PT1777236T (pt) 2017-02-13
EP1490409B1 (en) 2008-12-31
EP1777236A1 (en) 2007-04-25
NZ535968A (en) 2006-08-31
EP1777236B8 (en) 2017-02-22
DE60325565D1 (de) 2009-02-12
ATE419278T1 (de) 2009-01-15
ES2318117T3 (es) 2009-05-01
CA2480389C (en) 2012-10-09
BR0308768A (pt) 2005-02-15
PT1490409E (pt) 2009-04-03
AU2003216633A1 (en) 2003-10-08
EP1490409A1 (en) 2004-12-29
CY1118584T1 (el) 2017-07-12
JP2005526153A (ja) 2005-09-02
JP2010132925A (ja) 2010-06-17
DK1490409T3 (da) 2009-03-23
JP5361767B2 (ja) 2013-12-04
CY1108911T1 (el) 2014-07-02
MXPA04009339A (es) 2005-01-25

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