DK177489D0 - CHOLESTA STATE DERIVATIVES AS INTERMEDIATES FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES - Google Patents

CHOLESTA STATE DERIVATIVES AS INTERMEDIATES FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES

Info

Publication number
DK177489D0
DK177489D0 DK177489A DK177489A DK177489D0 DK 177489 D0 DK177489 D0 DK 177489D0 DK 177489 A DK177489 A DK 177489A DK 177489 A DK177489 A DK 177489A DK 177489 D0 DK177489 D0 DK 177489D0
Authority
DK
Denmark
Prior art keywords
derivatives
homovitamin
cholesta
intermediates
preparation
Prior art date
Application number
DK177489A
Other languages
Danish (da)
Other versions
DK158989B (en
DK158989C (en
DK177489A (en
Inventor
Hector F Deluca
Nobuo Ikekawa
Yoko Tanaka
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of DK177489D0 publication Critical patent/DK177489D0/en
Publication of DK177489A publication Critical patent/DK177489A/en
Publication of DK158989B publication Critical patent/DK158989B/en
Application granted granted Critical
Publication of DK158989C publication Critical patent/DK158989C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
DK177489A 1984-10-04 1989-04-13 CHOLESTA STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATE FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES DK158989C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US65754984A 1984-10-04 1984-10-04
US65754984 1984-10-04
US8501571 1985-08-19
PCT/US1985/001571 WO1986002078A1 (en) 1984-10-04 1985-08-19 Vitamin d derivatives and methods for preparing same

Publications (4)

Publication Number Publication Date
DK177489D0 true DK177489D0 (en) 1989-04-13
DK177489A DK177489A (en) 1989-04-13
DK158989B DK158989B (en) 1990-08-13
DK158989C DK158989C (en) 1991-01-21

Family

ID=24637652

Family Applications (5)

Application Number Title Priority Date Filing Date
DK260086A DK154290C (en) 1984-10-04 1986-06-03 VITAMIN-D DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE
DK111188A DK159389C (en) 1984-10-04 1988-03-02 CHOLESTAGE STAGE OR TRIEND DERIVATIVES THAT MAY BE USED AS INTERMEDIATES FOR USE IN THE PREPARATION OF 24-HOMOVITAMIN-D3 DERIVATIVES
DK177489A DK158989C (en) 1984-10-04 1989-04-13 CHOLESTA STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATE FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES
DK015390A DK158991C (en) 1984-10-04 1990-01-19 CHOLE STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATES FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES
DK015290A DK158990C (en) 1984-10-04 1990-01-19 CHOLESTA STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATE FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK260086A DK154290C (en) 1984-10-04 1986-06-03 VITAMIN-D DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE
DK111188A DK159389C (en) 1984-10-04 1988-03-02 CHOLESTAGE STAGE OR TRIEND DERIVATIVES THAT MAY BE USED AS INTERMEDIATES FOR USE IN THE PREPARATION OF 24-HOMOVITAMIN-D3 DERIVATIVES

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK015390A DK158991C (en) 1984-10-04 1990-01-19 CHOLE STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATES FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES
DK015290A DK158990C (en) 1984-10-04 1990-01-19 CHOLESTA STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATE FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES

Country Status (13)

Country Link
EP (1) EP0197949A1 (en)
JP (3) JPS62500301A (en)
AU (2) AU582789B2 (en)
BE (1) BE903376A (en)
CH (1) CH672920A5 (en)
DE (2) DE3590488C2 (en)
DK (5) DK154290C (en)
FR (1) FR2571369B1 (en)
GB (2) GB2167070B (en)
IE (1) IE58104B1 (en)
IT (1) IT1190401B (en)
NL (1) NL8520265A (en)
WO (1) WO1986002078A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989010351A1 (en) * 1988-04-21 1989-11-02 Leo Pharmaceutical Products Ltd. A/S (Løvens Kemis Novel vitamin d analogues
KR940003360B1 (en) * 1988-04-29 1994-04-21 위스콘신 알럼나이 리써취 파운데이션 Side chain unsaturated 1 alpha-hydroxyvitamin d homologs
US4927815A (en) * 1988-04-29 1990-05-22 Wisconsin Alumni Research Foundation Compounds effective in inducing cell differentiation and process for preparing same
US5063221A (en) * 1989-04-05 1991-11-05 Chugai Seiyaku Kabushiki Kaisha Treatment for hyperparathyroidism with use of vitamin d derivatives
DE3933034A1 (en) * 1989-10-02 1991-04-11 Schering Ag 24-HOMO-VITAMIN-D DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5891865A (en) * 1996-10-04 1999-04-06 Wisconsin Alumni Research Foundation Treatment of arthritic disease induced by infectious agents
US20080293647A1 (en) 2004-11-12 2008-11-27 Luciano Adorini Combined Use Of Vitamin D Derivatives And Anti-Proliferative Agents For Treating Bladder Cancer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3833622A (en) * 1969-03-17 1974-09-03 Upjohn Co Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds
US3880894A (en) * 1974-05-24 1975-04-29 Wisconsin Alumni Res Found 1,25-Dihydroxyergocalciferol
AU527805B2 (en) * 1978-07-27 1983-03-24 Research Institute For Medicine And Chemistry Inc. 1alpha, 1beta dihydroxy steroid-5-enes
US4225596A (en) * 1978-10-13 1980-09-30 Wisconsin Alumni Research Foundation Method for treating calcium imbalance and improving calcium absorption in mammals
US4448721A (en) * 1982-09-20 1984-05-15 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 compounds and process for preparing same
US4508651A (en) * 1983-03-21 1985-04-02 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
NL193245C (en) * 1983-05-09 1999-04-02 Wisconsin Alumni Res Found A 1,25-dihydroxyvitamin D2 related compound and pharmaceutical composition having a calcium metabolism-regulating action containing such a compound.

Also Published As

Publication number Publication date
DK158990B (en) 1990-08-13
GB2188932B (en) 1988-09-01
DK158989B (en) 1990-08-13
DE3590488C2 (en) 1992-10-01
IT8522359A0 (en) 1985-10-04
WO1986002078A1 (en) 1986-04-10
GB2188932A (en) 1987-10-14
FR2571369A1 (en) 1986-04-11
NL8520265A (en) 1986-09-01
JPH0569103B2 (en) 1993-09-30
CH672920A5 (en) 1990-01-15
DK111188A (en) 1988-03-02
DK15290A (en) 1990-01-19
IE852443L (en) 1986-04-04
FR2571369B1 (en) 1987-12-04
DE3590488T (en) 1986-10-09
BE903376A (en) 1986-02-03
GB8524479D0 (en) 1985-11-06
DK158990C (en) 1991-01-21
JPH0635475B2 (en) 1994-05-11
DK158989C (en) 1991-01-21
DK15390A (en) 1990-01-19
DK15290D0 (en) 1990-01-19
DK159389C (en) 1991-03-11
DK177489A (en) 1989-04-13
DK158991B (en) 1990-08-13
JPH0689022B2 (en) 1994-11-09
DK15390D0 (en) 1990-01-19
AU2761488A (en) 1989-06-08
GB8709579D0 (en) 1987-05-28
DK111188D0 (en) 1988-03-02
JPH05222089A (en) 1993-08-31
DK154290B (en) 1988-10-31
AU582789B2 (en) 1989-04-13
AU4776185A (en) 1986-04-17
AU605007B2 (en) 1991-01-03
DK260086D0 (en) 1986-06-03
JPH05178887A (en) 1993-07-20
EP0197949A1 (en) 1986-10-22
DK260086A (en) 1986-06-03
JPS62500301A (en) 1987-02-05
IE58104B1 (en) 1993-06-30
IT1190401B (en) 1988-02-16
GB2167070B (en) 1988-09-01
DK159389B (en) 1990-10-08
DK158991C (en) 1991-01-21
DK154290C (en) 1989-03-28
GB2167070A (en) 1986-05-21

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