DK154290C - VITAMIN-D DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE - Google Patents

VITAMIN-D DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE

Info

Publication number
DK154290C
DK154290C DK260086A DK260086A DK154290C DK 154290 C DK154290 C DK 154290C DK 260086 A DK260086 A DK 260086A DK 260086 A DK260086 A DK 260086A DK 154290 C DK154290 C DK 154290C
Authority
DK
Denmark
Prior art keywords
vitamin
derivatives
pharmaceutical preparations
preparations containing
pharmaceutical
Prior art date
Application number
DK260086A
Other languages
Danish (da)
Other versions
DK154290B (en
DK260086D0 (en
DK260086A (en
Inventor
Hector F Deluca
Nobuo Ikekawa
Yoko Tanaka
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of DK260086D0 publication Critical patent/DK260086D0/en
Publication of DK260086A publication Critical patent/DK260086A/en
Publication of DK154290B publication Critical patent/DK154290B/en
Application granted granted Critical
Publication of DK154290C publication Critical patent/DK154290C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK260086A 1984-10-04 1986-06-03 VITAMIN-D DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE DK154290C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US65754984A 1984-10-04 1984-10-04
US65754984 1984-10-04
US8501571 1985-08-19
PCT/US1985/001571 WO1986002078A1 (en) 1984-10-04 1985-08-19 Vitamin d derivatives and methods for preparing same

Publications (4)

Publication Number Publication Date
DK260086D0 DK260086D0 (en) 1986-06-03
DK260086A DK260086A (en) 1986-06-03
DK154290B DK154290B (en) 1988-10-31
DK154290C true DK154290C (en) 1989-03-28

Family

ID=24637652

Family Applications (5)

Application Number Title Priority Date Filing Date
DK260086A DK154290C (en) 1984-10-04 1986-06-03 VITAMIN-D DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE
DK111188A DK159389C (en) 1984-10-04 1988-03-02 CHOLESTAGE STAGE OR TRIEND DERIVATIVES THAT MAY BE USED AS INTERMEDIATES FOR USE IN THE PREPARATION OF 24-HOMOVITAMIN-D3 DERIVATIVES
DK177489A DK158989C (en) 1984-10-04 1989-04-13 CHOLESTA STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATE FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES
DK015290A DK158990C (en) 1984-10-04 1990-01-19 CHOLESTA STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATE FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES
DK015390A DK158991C (en) 1984-10-04 1990-01-19 CHOLE STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATES FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES

Family Applications After (4)

Application Number Title Priority Date Filing Date
DK111188A DK159389C (en) 1984-10-04 1988-03-02 CHOLESTAGE STAGE OR TRIEND DERIVATIVES THAT MAY BE USED AS INTERMEDIATES FOR USE IN THE PREPARATION OF 24-HOMOVITAMIN-D3 DERIVATIVES
DK177489A DK158989C (en) 1984-10-04 1989-04-13 CHOLESTA STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATE FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES
DK015290A DK158990C (en) 1984-10-04 1990-01-19 CHOLESTA STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATE FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES
DK015390A DK158991C (en) 1984-10-04 1990-01-19 CHOLE STAGE DERIVATIVES THAT MAY BE USED AS INTERMEDIATES FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES

Country Status (13)

Country Link
EP (1) EP0197949A1 (en)
JP (3) JPS62500301A (en)
AU (2) AU582789B2 (en)
BE (1) BE903376A (en)
CH (1) CH672920A5 (en)
DE (2) DE3590488T (en)
DK (5) DK154290C (en)
FR (1) FR2571369B1 (en)
GB (2) GB2167070B (en)
IE (1) IE58104B1 (en)
IT (1) IT1190401B (en)
NL (1) NL8520265A (en)
WO (1) WO1986002078A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0412110B1 (en) * 1988-04-21 1993-07-07 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) Novel vitamin d analogues
US4927815A (en) * 1988-04-29 1990-05-22 Wisconsin Alumni Research Foundation Compounds effective in inducing cell differentiation and process for preparing same
AU629831B2 (en) * 1988-04-29 1992-10-15 Wisconsin Alumni Research Foundation Side chain unsaturated 1 alpha-hydroxyvitamin d homologs for the treatment of leukemia
GB2229921B (en) * 1989-04-05 1992-12-16 Chugai Pharmaceutical Co Ltd Treatment for hyperparathyroidism with use of vitamin d derivatives
DE3933034A1 (en) * 1989-10-02 1991-04-11 Schering Ag 24-HOMO-VITAMIN-D DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5891865A (en) * 1996-10-04 1999-04-06 Wisconsin Alumni Research Foundation Treatment of arthritic disease induced by infectious agents
JP2008519808A (en) 2004-11-12 2008-06-12 ビオエクセル エスピーエー Combination of vitamin D derivatives and antiproliferative drugs for the treatment of bladder cancer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3833622A (en) * 1969-03-17 1974-09-03 Upjohn Co Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds
US3880894A (en) * 1974-05-24 1975-04-29 Wisconsin Alumni Res Found 1,25-Dihydroxyergocalciferol
AU527805B2 (en) * 1978-07-27 1983-03-24 Research Institute For Medicine And Chemistry Inc. 1alpha, 1beta dihydroxy steroid-5-enes
US4225596A (en) * 1978-10-13 1980-09-30 Wisconsin Alumni Research Foundation Method for treating calcium imbalance and improving calcium absorption in mammals
US4448721A (en) * 1982-09-20 1984-05-15 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 compounds and process for preparing same
US4508651A (en) * 1983-03-21 1985-04-02 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
CH665834A5 (en) * 1983-05-09 1988-06-15 Wisconsin Alumni Res Found METHOD FOR PRODUCING 1ALPHA, 25-DIHYDROXYLATED VITAMIN D (2) AND RELATED COMPOUNDS.

Also Published As

Publication number Publication date
DK15290D0 (en) 1990-01-19
AU605007B2 (en) 1991-01-03
GB2167070B (en) 1988-09-01
DK15390A (en) 1990-01-19
DK158990C (en) 1991-01-21
GB2188932B (en) 1988-09-01
DK15390D0 (en) 1990-01-19
JPH0635475B2 (en) 1994-05-11
DK158990B (en) 1990-08-13
DK158989B (en) 1990-08-13
DK154290B (en) 1988-10-31
BE903376A (en) 1986-02-03
GB8524479D0 (en) 1985-11-06
IE58104B1 (en) 1993-06-30
DE3590488C2 (en) 1992-10-01
JPH05222089A (en) 1993-08-31
GB2188932A (en) 1987-10-14
IT8522359A0 (en) 1985-10-04
DK260086D0 (en) 1986-06-03
AU582789B2 (en) 1989-04-13
DK159389C (en) 1991-03-11
DK158991C (en) 1991-01-21
GB2167070A (en) 1986-05-21
DK158989C (en) 1991-01-21
IE852443L (en) 1986-04-04
DK158991B (en) 1990-08-13
DK111188A (en) 1988-03-02
DK260086A (en) 1986-06-03
NL8520265A (en) 1986-09-01
EP0197949A1 (en) 1986-10-22
JPH0569103B2 (en) 1993-09-30
DK159389B (en) 1990-10-08
IT1190401B (en) 1988-02-16
AU4776185A (en) 1986-04-17
DK15290A (en) 1990-01-19
GB8709579D0 (en) 1987-05-28
DE3590488T (en) 1986-10-09
JPS62500301A (en) 1987-02-05
DK177489D0 (en) 1989-04-13
FR2571369A1 (en) 1986-04-11
JPH05178887A (en) 1993-07-20
DK111188D0 (en) 1988-03-02
WO1986002078A1 (en) 1986-04-10
JPH0689022B2 (en) 1994-11-09
CH672920A5 (en) 1990-01-15
FR2571369B1 (en) 1987-12-04
AU2761488A (en) 1989-06-08
DK177489A (en) 1989-04-13

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