IT1190401B - VITAMIN D DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR PRECURSORS - Google Patents

VITAMIN D DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR PRECURSORS

Info

Publication number
IT1190401B
IT1190401B IT22359/85A IT2235985A IT1190401B IT 1190401 B IT1190401 B IT 1190401B IT 22359/85 A IT22359/85 A IT 22359/85A IT 2235985 A IT2235985 A IT 2235985A IT 1190401 B IT1190401 B IT 1190401B
Authority
IT
Italy
Prior art keywords
precursors
vitamin
derivatives
pharmaceutical compositions
compositions containing
Prior art date
Application number
IT22359/85A
Other languages
Italian (it)
Other versions
IT8522359A0 (en
Inventor
Hector F Deluca
Nobuo Ikekawa
Tanaka Yoko
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of IT8522359A0 publication Critical patent/IT8522359A0/en
Application granted granted Critical
Publication of IT1190401B publication Critical patent/IT1190401B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT22359/85A 1984-10-04 1985-10-04 VITAMIN D DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR PRECURSORS IT1190401B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65754984A 1984-10-04 1984-10-04

Publications (2)

Publication Number Publication Date
IT8522359A0 IT8522359A0 (en) 1985-10-04
IT1190401B true IT1190401B (en) 1988-02-16

Family

ID=24637652

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22359/85A IT1190401B (en) 1984-10-04 1985-10-04 VITAMIN D DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR PRECURSORS

Country Status (13)

Country Link
EP (1) EP0197949A1 (en)
JP (3) JPS62500301A (en)
AU (2) AU582789B2 (en)
BE (1) BE903376A (en)
CH (1) CH672920A5 (en)
DE (2) DE3590488C2 (en)
DK (5) DK154290C (en)
FR (1) FR2571369B1 (en)
GB (2) GB2167070B (en)
IE (1) IE58104B1 (en)
IT (1) IT1190401B (en)
NL (1) NL8520265A (en)
WO (1) WO1986002078A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2711161B2 (en) * 1988-04-21 1998-02-10 レオ・ファーマシューティカル・プロダクツ・リミテッド・エイ／エス（レーベンス・ケミスケ・ファブリック・プロデュクチオンスアクチーセルスカブ） Novel vitamin D analog
US4927815A (en) * 1988-04-29 1990-05-22 Wisconsin Alumni Research Foundation Compounds effective in inducing cell differentiation and process for preparing same
RU2057117C1 (en) * 1988-04-29 1996-03-27 Висконсин Алюмни Рисерч Фаундейшн HOMOLOGS OF 1α-HYDROXYVITAMIN D3 WITH SATURATED SIDE CHAIN, COMPOSITION PROMOTING STIMULATION AND ENHANCEMENT OF HUMAN LEUKEMIA MALIGNANT CELL DIFFERENTIATION, A METHOD OF STIMULATION AND ENHANCEMENT OF HUMAN LEUKEMIA MALIGNANT CELL DIFFERENTIATION
GB2229921B (en) * 1989-04-05 1992-12-16 Chugai Pharmaceutical Co Ltd Treatment for hyperparathyroidism with use of vitamin d derivatives
DE3933034A1 (en) * 1989-10-02 1991-04-11 Schering Ag 24-HOMO-VITAMIN-D DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5891865A (en) * 1996-10-04 1999-04-06 Wisconsin Alumni Research Foundation Treatment of arthritic disease induced by infectious agents
WO2006051106A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3833622A (en) * 1969-03-17 1974-09-03 Upjohn Co Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds
US3880894A (en) * 1974-05-24 1975-04-29 Wisconsin Alumni Res Found 1,25-Dihydroxyergocalciferol
AU527805B2 (en) * 1978-07-27 1983-03-24 Research Institute For Medicine And Chemistry Inc. 1alpha, 1beta dihydroxy steroid-5-enes
US4225596A (en) * 1978-10-13 1980-09-30 Wisconsin Alumni Research Foundation Method for treating calcium imbalance and improving calcium absorption in mammals
US4448721A (en) * 1982-09-20 1984-05-15 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 compounds and process for preparing same
US4508651A (en) * 1983-03-21 1985-04-02 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
WO1984004527A1 (en) * 1983-05-09 1984-11-22 Wisconsin Alumni Res Found PROCESS FOR THE PREPARATION OF 1alpha,25-DIHYDROXYLATED VITAMIN D2 AND RELATED COMPOUNDS

Also Published As

Publication number Publication date
AU2761488A (en) 1989-06-08
GB2188932A (en) 1987-10-14
GB2167070A (en) 1986-05-21
NL8520265A (en) 1986-09-01
GB2188932B (en) 1988-09-01
JPH05222089A (en) 1993-08-31
DK158990B (en) 1990-08-13
DK15290A (en) 1990-01-19
DK158989B (en) 1990-08-13
JPH0689022B2 (en) 1994-11-09
BE903376A (en) 1986-02-03
JPH0635475B2 (en) 1994-05-11
IE58104B1 (en) 1993-06-30
DK158991B (en) 1990-08-13
AU605007B2 (en) 1991-01-03
DK111188A (en) 1988-03-02
FR2571369A1 (en) 1986-04-11
GB8524479D0 (en) 1985-11-06
DK111188D0 (en) 1988-03-02
WO1986002078A1 (en) 1986-04-10
CH672920A5 (en) 1990-01-15
DK15390D0 (en) 1990-01-19
JPS62500301A (en) 1987-02-05
DK154290C (en) 1989-03-28
DK260086A (en) 1986-06-03
DK177489A (en) 1989-04-13
DK158991C (en) 1991-01-21
DK159389C (en) 1991-03-11
IE852443L (en) 1986-04-04
EP0197949A1 (en) 1986-10-22
DK15390A (en) 1990-01-19
DK177489D0 (en) 1989-04-13
AU4776185A (en) 1986-04-17
DK154290B (en) 1988-10-31
DK159389B (en) 1990-10-08
IT8522359A0 (en) 1985-10-04
DK15290D0 (en) 1990-01-19
DE3590488T (en) 1986-10-09
DK158990C (en) 1991-01-21
GB8709579D0 (en) 1987-05-28
FR2571369B1 (en) 1987-12-04
JPH05178887A (en) 1993-07-20
DK158989C (en) 1991-01-21
AU582789B2 (en) 1989-04-13
DE3590488C2 (en) 1992-10-01
JPH0569103B2 (en) 1993-09-30
DK260086D0 (en) 1986-06-03
GB2167070B (en) 1988-09-01

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