DK184588D0 - INTERMEDIATES FOR USE IN THE PREPARATION OF 1ALFA, 25-DIHYDROXYLERED VITAMIN D2 DERIVATIVES - Google Patents

INTERMEDIATES FOR USE IN THE PREPARATION OF 1ALFA, 25-DIHYDROXYLERED VITAMIN D2 DERIVATIVES

Info

Publication number
DK184588D0
DK184588D0 DK184588A DK184588A DK184588D0 DK 184588 D0 DK184588 D0 DK 184588D0 DK 184588 A DK184588 A DK 184588A DK 184588 A DK184588 A DK 184588A DK 184588 D0 DK184588 D0 DK 184588D0
Authority
DK
Denmark
Prior art keywords
dihydroxylered
1alfa
intermediates
vitamin
derivatives
Prior art date
Application number
DK184588A
Other languages
Danish (da)
Other versions
DK172567B1 (en
DK184588A (en
Inventor
Hector F Deluca
Heinrich K Schnoes
Rafal R Sicinski
Yoko Tanaka
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of DK184588D0 publication Critical patent/DK184588D0/en
Publication of DK184588A publication Critical patent/DK184588A/en
Application granted granted Critical
Publication of DK172567B1 publication Critical patent/DK172567B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
DK198801845A 1983-05-09 1988-04-06 3,5-cyclovitamin D2 derivative intermediates for use in the preparation of 1alpha, 25-dihydroxylated vitamin D2 derivatives DK172567B1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US49286383A 1983-05-09 1983-05-09
US49286383 1983-05-09
US60732784A 1984-05-04 1984-05-04
US60732784 1984-05-04
PCT/US1984/000714 WO1984004527A1 (en) 1983-05-09 1984-05-09 PROCESS FOR THE PREPARATION OF 1alpha,25-DIHYDROXYLATED VITAMIN D2 AND RELATED COMPOUNDS
US8400714 1984-05-09

Publications (3)

Publication Number Publication Date
DK184588D0 true DK184588D0 (en) 1988-04-06
DK184588A DK184588A (en) 1988-04-06
DK172567B1 DK172567B1 (en) 1999-01-18

Family

ID=27050897

Family Applications (3)

Application Number Title Priority Date Filing Date
DK008685A DK171397B1 (en) 1983-05-09 1985-01-08 24-Epi-1alpha,25-dihydroxylated vitamin D2 derivatives, and preparations for pharmaceutical use which comprises these derivatives
DK198801845A DK172567B1 (en) 1983-05-09 1988-04-06 3,5-cyclovitamin D2 derivative intermediates for use in the preparation of 1alpha, 25-dihydroxylated vitamin D2 derivatives
DK199101832A DK172733B1 (en) 1983-05-09 1991-11-07 25-oxovitamin D2 derivative intermediates for use in the preparation of 1alpha, 25-dihydroxylated vitamin D2 derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK008685A DK171397B1 (en) 1983-05-09 1985-01-08 24-Epi-1alpha,25-dihydroxylated vitamin D2 derivatives, and preparations for pharmaceutical use which comprises these derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK199101832A DK172733B1 (en) 1983-05-09 1991-11-07 25-oxovitamin D2 derivative intermediates for use in the preparation of 1alpha, 25-dihydroxylated vitamin D2 derivatives

Country Status (7)

Country Link
JP (3) JPH0651624B2 (en)
AU (1) AU568549B2 (en)
CH (1) CH665834A5 (en)
DE (4) DE3490215C2 (en)
DK (3) DK171397B1 (en)
NL (1) NL193245C (en)
WO (1) WO1984004527A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3590488T (en) * 1984-10-04 1986-10-09 Wisconsin Alumni Research Foundation, Madison, Wis. Vitamin D derivatives and processes for their preparation
WO1986004333A1 (en) * 1985-01-17 1986-07-31 Wisconsin Alumni Research Foundation Vitamin d derivatives and methods for preparing same
CA1341408C (en) * 1988-08-02 2002-12-10 Charles W. Bishop Method for treating and preventing loss of bone mass
US5104864A (en) * 1988-08-02 1992-04-14 Bone Care International, Inc. Method for treating and preventing loss of bone mass
US4973584A (en) * 1989-03-09 1990-11-27 Deluca Hector F Novel 1α-hydroxyvitamin D2 epimer and derivatives
JP2645130B2 (en) * 1989-03-31 1997-08-25 日清製粉株式会社 Steroid derivatives
GB8914963D0 (en) * 1989-06-29 1989-08-23 Leo Pharm Prod Ltd Chemical compounds
IN171426B (en) * 1990-02-14 1992-10-10 Wisconsin Alumni Res Found
US5795882A (en) * 1992-06-22 1998-08-18 Bone Care International, Inc. Method of treating prostatic diseases using delayed and/or sustained release vitamin D formulations
NZ254424A (en) * 1992-06-22 1997-09-22 Lunar Corp Pharmaceutical composition and use of 1 alpha hydroxy-pre-vitamin d
US5763429A (en) 1993-09-10 1998-06-09 Bone Care International, Inc. Method of treating prostatic diseases using active vitamin D analogues
US6573256B2 (en) 1996-12-30 2003-06-03 Bone Care International, Inc. Method of inhibiting angiogenesis using active vitamin D analogues
US6566353B2 (en) 1996-12-30 2003-05-20 Bone Care International, Inc. Method of treating malignancy associated hypercalcemia using active vitamin D analogues
US6503893B2 (en) 1996-12-30 2003-01-07 Bone Care International, Inc. Method of treating hyperproliferative diseases using active vitamin D analogues
BR9815442A (en) 1997-02-13 2001-08-21 Bone Care Int Inc Targeted therapeutic release of vitamin D compounds
US20090233889A1 (en) 2008-03-12 2009-09-17 Uttam Saha Stabilized 1,25-dihydroxyvitamin d2 and method of making same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4260549A (en) * 1979-05-21 1981-04-07 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
US4267117A (en) * 1978-06-19 1981-05-12 The Upjohn Company Compounds and process
US4269777A (en) * 1979-05-21 1981-05-26 Wisconsin Alumni Research Foundation Isotopically labeled vitamin D derivatives and processes for preparing same

Also Published As

Publication number Publication date
DK183291A (en) 1991-11-07
DK172733B1 (en) 1999-06-21
JPH0339505B2 (en) 1991-06-14
DK172567B1 (en) 1999-01-18
DK171397B1 (en) 1996-10-14
JPH0651624B2 (en) 1994-07-06
DE3490215T (en) 1985-05-15
JPH02288873A (en) 1990-11-28
DK183291D0 (en) 1991-11-07
JPH0610188B2 (en) 1994-02-09
NL193245B (en) 1998-12-01
DE3448412C2 (en) 1991-12-12
DK8685D0 (en) 1985-01-08
AU3011584A (en) 1984-12-04
DE3490215C2 (en) 1991-07-25
CH665834A5 (en) 1988-06-15
DK8685A (en) 1985-01-08
WO1984004527A1 (en) 1984-11-22
DK184588A (en) 1988-04-06
AU568549B2 (en) 1988-01-07
NL193245C (en) 1999-04-02
NL8420137A (en) 1985-04-01
JPH02288854A (en) 1990-11-28
DE3448360C2 (en) 1991-10-02
JPH02288829A (en) 1990-11-28

Similar Documents

Publication Publication Date Title
FI830922L (en) FOERSLUTNINGSBAR BEHAOLLARE MED HALKFRIA KANTER SOM UNDERLAETTAR OEPPNING OCH BEHANDLING
ES539852A0 (en) A NEW PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES. OF CARBAZOLONA.
ES520180A0 (en) PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF AMINOMETIL-5-ARIL-3-OXAZOLIDINONE-2.
DK184588A (en) INTERMEDIATES FOR USE IN THE PREPARATION OF 1ALFA, 25-DIHYDROXYLERED VITAMIN D2 DERIVATIVES
ES503188A0 (en) A PROCEDURE FOR THE PREPARATION OF A 1-BENZOIL-UREA 3-SUBSTITUTED
DK416888A (en) CEPHALOSPORINE COMPOUNDS, CRYSTALLINIC DERIVATIVES THEREOF, INTERMEDIATES FOR USE IN THE PRODUCTION OF CEPHALOSPORINE COMPOUNDS AND PROCEDURES FOR THE PRODUCTION OF CEPHALOSPORINE COMPOUNDS
DK177489A (en) CHOLESTA STATE DERIVATIVES AS INTERMEDIATES FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES
ES500455A0 (en) PROCEDURE FOR THE PREPARATION OF NEW UREA DERIVATIVES
ES533618A0 (en) PROCEDURE FOR THE PREPARATION OF NEW GUARNINA DERIVATIVES.
DK68784A (en) CONTINUOUS PROCEDURE FOR THE PREPARATION OF 5-OXO-2,4-DICHLOR-4-SUBSTITUTED PENTANNITRILS
DK56490D0 (en) HOMOCHOL STANDARD DERIVATIVES AS INTERMEDIATES FOR USE IN THE PREPARATION OF 26-HOMOVITAMIN D3 DERIVATIVES
DK296290A (en) INTERMEDIATES FOR USE IN THE PREPARATION OF PYRIMIDO (4,5-G) QUINOLINE DERIVATIVES OR SALTS THEREOF
DK451281A (en) PROCEDURE FOR THE PREPARATION OF CEPHALEXIN DERIVATIVES
ES500306A0 (en) PROCEDURE FOR THE PREPARATION OF NEW ESTE-ROIDE-ESPIRO-OXATIAZOLIDINE DERIVATIVES
ES508078A0 (en) "PROCEDURE FOR THE PREPARATION OF FORMAMIDINE DERIVATIVES".
DK422582A (en) OXIRANS USED AS INTERMEDIATES IN THE PREPARATION OF SUBSTITUTED 1-AZOLYL-2-HYDROXY ALKANDER DERIVATIVES
DK422382A (en) OXIRANS USED AS INTERMEDIATES IN THE PREPARATION OF SUBSTITUTED 2-HYDROXY-3-AZOLYL PROPANDER DERIVATIVES
NO166082C (en) INTERMEDIATES FOR USE IN THE PREPARATION OF IMIDAZOKINOLINON DERIVATIVES.
ES507775A0 (en) PROCEDURE FOR THE PREPARATION OF PIRIDINE DERIVATIVES.
ES547820A0 (en) PROCEDURE FOR THE PREPARATION OF NEW NUCLEOSID DERIVATIVES.
DK532283D0 (en) DIPEPTID SWEATER AND ITS APPLICATION FOR THE PREPARATION OF SWEDEN Aqueous Media
AR223763A1 (en) PROCEDURE FOR THE PREPARATION OF NEW ALCOXICARBONYL-3-BENZODIAZEPIN DERIVATIVES USABLE ESPECIALLY IN THERAPEUTICS
NO166081C (en) INTERMEDIATES FOR USE IN THE PREPARATION OF IMIDAZOKINOLIN DERIVATIVES
ES503408A0 (en) PROCEDURE FOR THE PREPARATION OF IMIDAZOLI-DIN-2,4-DIONA DERIVATIVES
AR229037A1 (en) PROCEDURE FOR THE PREPARATION OF NEW XANTINA DERIVATIVES

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed

Country of ref document: DK