DK1755664T3 - Vacciner med prrsv-underenhed - Google Patents
Vacciner med prrsv-underenhed Download PDFInfo
- Publication number
- DK1755664T3 DK1755664T3 DK05766550.7T DK05766550T DK1755664T3 DK 1755664 T3 DK1755664 T3 DK 1755664T3 DK 05766550 T DK05766550 T DK 05766550T DK 1755664 T3 DK1755664 T3 DK 1755664T3
- Authority
- DK
- Denmark
- Prior art keywords
- prrsv
- dna
- orf1
- group
- sequence
- Prior art date
Links
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10071—Demonstrated in vivo effect
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Claims (12)
1. Vaccine, som er i stand til at inducere et immunrespons mod PRRSV omfattende: en første del af PRRSV-ORF1-DNA, hvor delen er valgt fra gruppen bestående af SEQ ID Nos. 2-6, 9 og kombinationer deraf; og et farmakologisk bærestof.
2. Vaccine ifølge krav 1, yderligere omfattende en anden del af DNA fra PRRSV valgt fra gruppen bestående af mindst 21 tilstødende nukleotider fra en PRRSV ORF forskellig fra ORF1, mindst 21 tilstødende nukleotider fra PRRSV-ORF1 og kombinationer deraf.
3. Vaccine ifølge krav 1, yderligere omfattende en bestanddel valgt fra gruppen bestående af adjuvanser, excipienser og kombinationer deraf.
4. Anvendelse af en første del af PRRSV-ORF1-DNA, hvor delen er valgt fra gruppen bestående af SEQ ID Nos. 2-6, 9 og kombinationer deraf, til fremstilling af en sammensætning for at inducere et immunrespons mod PRRSV i et dyr, som er modtagelig for PRRSV-infektion, hvor sammensætningen er til indgivelse til dyret.
5. Anvendelse ifølge krav 4, hvor en anden indgivelse af sammensætningen er tilvejebragt.
6. Anvendelse ifølge krav 5, hvor sammensætningen yderligere omfatter en anden DNA-del valgt fra gruppen bestående af mindst 21 tilstødende nukleotider fra en PRRSV-ORF forskellig fra ORF1, mindst 21 tilstødende nukleotider fra ORF1 og kombinationer deraf.
7. Anvendelse ifølge krav 5, hvor sammensætningen yderligere omfatter en ingrediens valgt fra gruppen bestående af adjuvanser, excipienser og kombinationer deraf.
8. Vektor omfattende mindst en del af PRRSV-ORF1-DNA, hvor delen er valgt fra gruppen bestående af SEQ ID Nos. 2-6, 9 og kombinationer deraf.
9. Vektoren ifølge krav 8, hvor vektoren er et plasmid.
10. Vektoren ifølge krav 8, hvor vektoren yderligere omfatter en anden del af PRRSV-DNA valgt fra gruppen bestående af mindst 21 tilstødende nukleotider fra en PRRSV-ORF forskellig fra ORF1, mindst 21 tilstødende nukleotider fra ORF1 og kombinationer deraf.
11. Celle indeholdende et plasmid ifølge krav 9.
12. Celle ifølge krav 11, hvor plasmidet yderligere omfatter en anden del af PRRSV-DNA valgt fra gruppen bestående af mindst 21 tilstødende nukleotider fra et PRRSV-ORF forskellig fra ORF1, mindst 21 tilstødende nukleotider fra ORF1 og kombinationer deraf.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58135004P | 2004-06-17 | 2004-06-17 | |
| US11/154,617 US7722878B2 (en) | 2004-06-17 | 2005-06-16 | PRRSV subunit vaccines |
| PCT/US2005/021973 WO2006002193A2 (en) | 2004-06-17 | 2005-06-17 | Prrsv subunit vaccines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1755664T3 true DK1755664T3 (da) | 2015-08-24 |
Family
ID=35431312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05766550.7T DK1755664T3 (da) | 2004-06-17 | 2005-06-17 | Vacciner med prrsv-underenhed |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7722878B2 (da) |
| EP (1) | EP1755664B1 (da) |
| JP (1) | JP2008503221A (da) |
| KR (1) | KR20070028431A (da) |
| AR (1) | AR049825A1 (da) |
| AU (1) | AU2005258092A1 (da) |
| BR (1) | BRPI0510930A (da) |
| CA (1) | CA2570778A1 (da) |
| DK (1) | DK1755664T3 (da) |
| ES (1) | ES2546933T3 (da) |
| MX (1) | MXPA06014821A (da) |
| RU (1) | RU2007101531A (da) |
| TW (1) | TW200603825A (da) |
| WO (1) | WO2006002193A2 (da) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0839912A1 (en) | 1996-10-30 | 1998-05-06 | Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
| WO2000053787A1 (en) | 1999-03-08 | 2000-09-14 | Id-Lelystad, Instituut Voor Dierhouderij En Dierg Ezondheid B.V. | Prrsv vaccines |
| CA2650236C (en) | 1999-04-22 | 2016-01-12 | United States Of America, As Represented By The Secretary Of Agriculture | Porcine reproductive and respiratory syndrome vaccine, based on isolate ja-142 |
| TW200604526A (en) | 2004-06-18 | 2006-02-01 | Unviersity Of Minnesota | Identifying virally infected and vaccinated organisms |
| US7632636B2 (en) | 2004-09-21 | 2009-12-15 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome isolates and methods of use |
| WO2007002321A2 (en) | 2005-06-24 | 2007-01-04 | Regents Of The University Of Minnesota | Prrs viruses, infectious clones, mutants thereof, and methods of use |
| US8436337B2 (en) * | 2009-05-12 | 2013-05-07 | The State of Oregon Acting By and Through The State Board of Higher Education on Behalf of Oregon State Unitiversity | Amorphous multi-component metallic thin films for electronic devices |
| TWI627281B (zh) | 2009-09-02 | 2018-06-21 | 百靈佳殷格翰家畜藥品公司 | 降低ｐｃｖ－２組合物殺病毒活性之方法及具有改良免疫原性之ｐｃｖ－２組合物 |
| EA038012B1 (ru) | 2011-02-17 | 2021-06-23 | Бёрингер Ингельхайм Ветмедика Гмбх | Композиция на основе нового штамма prrsv или его белков, продукт, их применение, вирус prrsv, выделенная нк и рекомбинантный вектор экспрессии для получения этого вируса |
| CA2827337C (en) | 2011-02-17 | 2019-07-09 | Boehringer Ingelheim Vetmedica Gmbh | Commercial scale process for production of prrsv |
| WO2012129176A1 (en) * | 2011-03-18 | 2012-09-27 | The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Amorphous multi-component metal/metal oxide nanolaminate metamaterials and devices based thereon |
| WO2012153160A1 (es) | 2011-05-07 | 2012-11-15 | Laboratorio Avi-Mex, S.A. De C.V. | Vacuna recombinante contra prrs en vector viral |
| US9187731B2 (en) * | 2011-07-29 | 2015-11-17 | Boehringer Ingelheim Vetmedica Gmbh | PRRS virus inducing type I interferon in susceptible cells |
| WO2013017568A1 (en) | 2011-07-29 | 2013-02-07 | Boehringer Ingelheim Vetmedica Gmbh | INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF |
| CN105264618B (zh) | 2012-11-12 | 2018-06-05 | 俄勒冈州立大学 | 非晶金属薄膜非线性电阻器 |
| WO2014150822A2 (en) | 2013-03-15 | 2014-09-25 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use |
| ES2940691T3 (es) | 2013-12-20 | 2023-05-10 | Boehringer Ingelheim Vetmedica Gmbh | Variante de virus PRRS, clon de ADNc de virus PRRS europeo y usos de los mismos |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6773908B1 (en) * | 1992-10-30 | 2004-08-10 | Iowa State University Research Foundation, Inc. | Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV) |
| US6592873B1 (en) * | 1992-10-30 | 2003-07-15 | Iowa State University Research Foundation, Inc. | Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids |
| US20020012670A1 (en) * | 2000-01-26 | 2002-01-31 | Knut Elbers | Recombinant attenuation of porcine reproductive and respiratory syndrome (PRRSV) |
| US6841364B2 (en) * | 2002-01-22 | 2005-01-11 | Protatek International, Inc. | Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof |
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2005
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- 2005-06-17 DK DK05766550.7T patent/DK1755664T3/da active
- 2005-06-17 BR BRPI0510930-2A patent/BRPI0510930A/pt not_active Application Discontinuation
- 2005-06-17 AU AU2005258092A patent/AU2005258092A1/en not_active Abandoned
- 2005-06-17 EP EP05766550.7A patent/EP1755664B1/en active Active
- 2005-06-17 JP JP2007516840A patent/JP2008503221A/ja not_active Withdrawn
- 2005-06-17 KR KR1020067026720A patent/KR20070028431A/ko not_active Application Discontinuation
- 2005-06-17 WO PCT/US2005/021973 patent/WO2006002193A2/en active Application Filing
- 2005-06-17 MX MXPA06014821A patent/MXPA06014821A/es not_active Application Discontinuation
- 2005-06-17 CA CA002570778A patent/CA2570778A1/en not_active Abandoned
- 2005-06-17 ES ES05766550.7T patent/ES2546933T3/es active Active
- 2005-06-17 AR ARP050102515A patent/AR049825A1/es active Pending
- 2005-06-17 RU RU2007101531/13A patent/RU2007101531A/ru unknown
- 2005-06-17 TW TW094120169A patent/TW200603825A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006002193A2 (en) | 2006-01-05 |
| AU2005258092A1 (en) | 2006-01-05 |
| TW200603825A (en) | 2006-02-01 |
| EP1755664B1 (en) | 2015-06-10 |
| AR049825A1 (es) | 2006-09-06 |
| EP1755664A2 (en) | 2007-02-28 |
| US7722878B2 (en) | 2010-05-25 |
| KR20070028431A (ko) | 2007-03-12 |
| ES2546933T3 (es) | 2015-09-30 |
| US20080038293A1 (en) | 2008-02-14 |
| JP2008503221A (ja) | 2008-02-07 |
| WO2006002193A3 (en) | 2006-03-02 |
| RU2007101531A (ru) | 2008-07-27 |
| MXPA06014821A (es) | 2007-03-26 |
| CA2570778A1 (en) | 2006-01-05 |
| BRPI0510930A (pt) | 2007-11-20 |
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