DK175282B1 - Anvendelse af 4-[1-(2,3-dimetylfenyl)-ætyl]-1H-imidazol til fremstilling af lægemidler til perioperativ anvendelse - Google Patents
Anvendelse af 4-[1-(2,3-dimetylfenyl)-ætyl]-1H-imidazol til fremstilling af lægemidler til perioperativ anvendelse Download PDFInfo
- Publication number
- DK175282B1 DK175282B1 DK198900464A DK46489A DK175282B1 DK 175282 B1 DK175282 B1 DK 175282B1 DK 198900464 A DK198900464 A DK 198900464A DK 46489 A DK46489 A DK 46489A DK 175282 B1 DK175282 B1 DK 175282B1
- Authority
- DK
- Denmark
- Prior art keywords
- imidazole
- dimethylphenyl
- ethyl
- manufacture
- pharmaceutically acceptable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Anesthesiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8804683 | 1988-02-29 | ||
GB8804683A GB2215206B (en) | 1988-02-29 | 1988-02-29 | 4-substituted imidazole derivatives useful in perioperative care |
Publications (3)
Publication Number | Publication Date |
---|---|
DK46489D0 DK46489D0 (da) | 1989-02-02 |
DK46489A DK46489A (da) | 1989-08-30 |
DK175282B1 true DK175282B1 (da) | 2004-08-09 |
Family
ID=10632543
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK198900464A DK175282B1 (da) | 1988-02-29 | 1989-02-02 | Anvendelse af 4-[1-(2,3-dimetylfenyl)-ætyl]-1H-imidazol til fremstilling af lægemidler til perioperativ anvendelse |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0331374B1 (de) |
JP (1) | JP2856410B2 (de) |
KR (1) | KR0136790B1 (de) |
AT (1) | ATE101514T1 (de) |
AU (1) | AU611262B2 (de) |
CA (1) | CA1338556C (de) |
DE (1) | DE68913054T2 (de) |
DK (1) | DK175282B1 (de) |
GB (1) | GB2215206B (de) |
HU (1) | HU202751B (de) |
IE (1) | IE60538B1 (de) |
NZ (1) | NZ228125A (de) |
ZA (1) | ZA891493B (de) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI894911A0 (fi) * | 1989-10-17 | 1989-10-17 | Farmos Oy | En terapeutiskt vaerdefull foerening. |
GB9111732D0 (en) * | 1991-05-31 | 1991-07-24 | Orion Yhtymae Oy | The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs |
GB2281206A (en) * | 1993-08-25 | 1995-03-01 | Orion Yhtymae Oy | Use of dexmedetomidine |
US6028068A (en) * | 1995-12-28 | 2000-02-22 | The Procter & Gamble Company | Substituted 6H-1,3,4-thiadiazine-2-amines, the use thereof as anaesthetising, cardiovascular and hypometabolic agents, and a pharmaceutical composition containing them |
WO1997024352A1 (fr) * | 1995-12-28 | 1997-07-10 | The Procter & Gamble Company | 6-h-1,3,4-thiadiazine-2-amines substitues, leur utilisation en qualite d'agents anesthesiques, cardio-vasculaires et hypometaboliques, et composition pharmaceutique les contenant |
ATE207918T1 (de) * | 1995-12-28 | 2001-11-15 | Procter & Gamble | Substituierte 6-r-1,3,4-thiadiazin-2-amine, deren verwendung als anaesthetische, cardiovaskulare und hypometabolische mittel, und eine sie enthaltende pharmazeutische zubereitung |
AR015744A1 (es) * | 1998-04-01 | 2001-05-16 | Orion Corp | Uso de dexmedetomidina para sedacion en terapia intensiva |
EP1981880B1 (de) * | 2006-01-27 | 2010-02-24 | F.Hoffmann-La Roche Ag | Verwendung von 4-imidazol-derivaten für zns-erkrankungen |
AU2007312390B2 (en) | 2006-10-19 | 2013-03-28 | F. Hoffmann-La Roche Ag | Aminomethyl-4-imidazoles |
JP5064511B2 (ja) | 2006-11-02 | 2012-10-31 | エフ.ホフマン−ラ ロシュ アーゲー | 痕跡アミン関連受容体調節剤としての置換2−イミダゾール |
RU2456281C2 (ru) | 2006-11-16 | 2012-07-20 | Ф. Хоффманн-Ля Рош Аг | Замещенные 4-имидазолы, способ их получения и их применение |
ATE509628T1 (de) | 2006-12-13 | 2011-06-15 | Hoffmann La Roche | Neue 2-imidazole als liganden für trace amine associated receptors (taar) |
US20080146523A1 (en) | 2006-12-18 | 2008-06-19 | Guido Galley | Imidazole derivatives |
BRPI0806940A2 (pt) | 2007-02-02 | 2014-05-06 | Hoffmann La Roche | 2-amino-oxazolinas como ligantes taar1 para distúrbios do snc |
MX2009008465A (es) | 2007-02-15 | 2009-08-20 | Hoffmann La Roche | Nuevas 2-aminooxazolinas como ligandos de taar1. |
AU2008270445A1 (en) | 2007-07-02 | 2009-01-08 | F. Hoffmann-La Roche Ag | 2 -imidazolines having a good affinity to the trace amine associated receptors (TAARs) |
MX2009013745A (es) | 2007-07-03 | 2010-01-26 | Hoffmann La Roche | 4-imidazolinas y su uso como antidepresivos. |
CN101765587A (zh) | 2007-07-27 | 2010-06-30 | 弗·哈夫曼-拉罗切有限公司 | 作为taar配体的2-氮杂环丁烷甲胺类和2-吡咯烷甲胺类 |
CA2695331A1 (en) | 2007-08-03 | 2009-02-12 | F. Hoffmann-La Roche Ag | Pyridinecarboxamide and benzamide derivatives as taar1 ligands |
US8242153B2 (en) | 2008-07-24 | 2012-08-14 | Hoffmann-La Roche Inc. | 4,5-dihydro-oxazol-2YL derivatives |
EP2395999B1 (de) | 2009-02-13 | 2017-09-13 | Allergan, Inc. | Pharmazeutische zusammensetzungen mit (3-(1-(1h-imidazol-4-yl)ethyl)-2-methylphenyl)methanol |
US8354441B2 (en) | 2009-11-11 | 2013-01-15 | Hoffmann-La Roche Inc. | Oxazoline derivatives |
US9452980B2 (en) | 2009-12-22 | 2016-09-27 | Hoffmann-La Roche Inc. | Substituted benzamides |
US9095576B2 (en) | 2011-11-21 | 2015-08-04 | Allergan, Inc. | Pharmaceutical compositions comprising 4-[1-(2,3-dimethylphenyl)ethyl]-3H-imidazole derivatives for treating retinal diseases |
RU2648449C2 (ru) | 2013-10-07 | 2018-03-26 | ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. | Способы и композиции для трансдермальной доставки неседативного количества дексмедетомидина |
TWI629066B (zh) | 2013-10-07 | 2018-07-11 | 帝國製藥美國股份有限公司 | 使用右美托咪啶經皮組成物用於治療注意力不足過動症、焦慮及失眠的方法及組成物 |
RU2018105761A (ru) | 2013-10-07 | 2019-02-26 | ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. | Устройства для трансдермальной доставки дексмедетомидина и способы их применения |
BR112018015389B1 (pt) | 2016-03-17 | 2023-12-19 | F. Hoffmann-La Roche Ag | Derivado de 5-etil-4-metil-pirazol-3-carboxamida, seu processo de fabricação, preparação farmacêutica oral e uso |
CA3038354C (en) * | 2016-10-31 | 2021-08-17 | Teikoku Pharma Usa, Inc. | Methods of managing pain using dexmedetomidine transdermal delivery devices |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3190802A (en) | 1961-10-09 | 1965-06-22 | Boehringer Sohn Ingelheim | Shaving composition and method of using same |
GB2101114B (en) * | 1981-07-10 | 1985-05-22 | Farmos Group Ltd | Substituted imidazole derivatives and their preparation and use |
FI844786A0 (fi) * | 1984-12-04 | 1984-12-04 | Farmos Oy | Terapeutiskt utnyttjbar foerening. |
FI864570A0 (fi) * | 1986-11-11 | 1986-11-11 | Farmos Oy | Terapeutiskt anvaendbar foerening. |
GB2206880B (en) * | 1987-07-16 | 1991-04-24 | Farmos Oy | Optical isomers of an imidazole derivative |
-
1988
- 1988-02-29 GB GB8804683A patent/GB2215206B/en not_active Expired - Fee Related
-
1989
- 1989-02-02 DK DK198900464A patent/DK175282B1/da not_active IP Right Cessation
- 1989-02-23 AU AU30272/89A patent/AU611262B2/en not_active Expired
- 1989-02-24 NZ NZ228125A patent/NZ228125A/en unknown
- 1989-02-24 AT AT89301866T patent/ATE101514T1/de not_active IP Right Cessation
- 1989-02-24 DE DE68913054T patent/DE68913054T2/de not_active Expired - Fee Related
- 1989-02-24 EP EP89301866A patent/EP0331374B1/de not_active Expired - Lifetime
- 1989-02-27 HU HU89917A patent/HU202751B/hu not_active IP Right Cessation
- 1989-02-27 JP JP1048391A patent/JP2856410B2/ja not_active Expired - Lifetime
- 1989-02-27 ZA ZA891493A patent/ZA891493B/xx unknown
- 1989-02-27 KR KR1019890002361A patent/KR0136790B1/ko not_active IP Right Cessation
- 1989-02-28 CA CA000592371A patent/CA1338556C/en not_active Expired - Lifetime
- 1989-02-28 IE IE63989A patent/IE60538B1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0331374B1 (de) | 1994-02-16 |
HUT51139A (en) | 1990-04-28 |
CA1338556C (en) | 1996-08-27 |
DK46489D0 (da) | 1989-02-02 |
EP0331374A2 (de) | 1989-09-06 |
JPH01294623A (ja) | 1989-11-28 |
KR890012647A (ko) | 1989-09-18 |
GB2215206A (en) | 1989-09-20 |
IE60538B1 (en) | 1994-07-27 |
HU202751B (en) | 1991-04-29 |
DE68913054T2 (de) | 1994-07-07 |
DE68913054D1 (de) | 1994-03-24 |
JP2856410B2 (ja) | 1999-02-10 |
AU3027289A (en) | 1989-08-31 |
AU611262B2 (en) | 1991-06-06 |
ZA891493B (en) | 1989-11-29 |
ATE101514T1 (de) | 1994-03-15 |
DK46489A (da) | 1989-08-30 |
GB8804683D0 (en) | 1988-03-30 |
EP0331374A3 (en) | 1990-10-10 |
GB2215206B (en) | 1991-07-03 |
KR0136790B1 (ko) | 1998-04-25 |
NZ228125A (en) | 1996-12-20 |
IE890639L (en) | 1989-08-29 |
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