DK1751181T3 - BINDINGSDELE, DER ER BASERET PÅ HAJ IgNAR-DOMÆNER - Google Patents
BINDINGSDELE, DER ER BASERET PÅ HAJ IgNAR-DOMÆNERInfo
- Publication number
- DK1751181T3 DK1751181T3 DK05744734.4T DK05744734T DK1751181T3 DK 1751181 T3 DK1751181 T3 DK 1751181T3 DK 05744734 T DK05744734 T DK 05744734T DK 1751181 T3 DK1751181 T3 DK 1751181T3
- Authority
- DK
- Denmark
- Prior art keywords
- haj
- parts based
- binding parts
- ignar domains
- ignar
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/461—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from fish
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
- C07K16/464—Igs containing CDR-residues from one specie grafted between FR-residues from another
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57584504P | 2004-06-02 | 2004-06-02 | |
PCT/AU2005/000789 WO2005118629A1 (en) | 2004-06-02 | 2005-06-02 | BINDING MOIETIES BASED ON SHARK IgNAR DOMAINS |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1751181T3 true DK1751181T3 (da) | 2012-11-26 |
Family
ID=35462883
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK10179638.1T DK2330121T3 (da) | 2004-06-02 | 2005-06-02 | Bindingsdele baseret på haj-IgNar-domæner |
DK05744734.4T DK1751181T3 (da) | 2004-06-02 | 2005-06-02 | BINDINGSDELE, DER ER BASERET PÅ HAJ IgNAR-DOMÆNER |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK10179638.1T DK2330121T3 (da) | 2004-06-02 | 2005-06-02 | Bindingsdele baseret på haj-IgNar-domæner |
Country Status (7)
Country | Link |
---|---|
US (3) | US7977071B2 (da) |
EP (3) | EP2330121B1 (da) |
JP (2) | JP2008511286A (da) |
AU (3) | AU2005250055B2 (da) |
CA (1) | CA2567655C (da) |
DK (2) | DK2330121T3 (da) |
WO (1) | WO2005118629A1 (da) |
Families Citing this family (68)
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US9453251B2 (en) | 2002-10-08 | 2016-09-27 | Pfenex Inc. | Expression of mammalian proteins in Pseudomonas fluorescens |
AU2005269527B2 (en) | 2004-07-26 | 2011-12-01 | Pfenex Inc. | Process for improved protein expression by strain engineering |
JP5444553B2 (ja) | 2007-04-27 | 2014-03-19 | フェネックス インコーポレイテッド | 微生物宿主を迅速にスクリーニングして、異種タンパク質発現の収率および/または質が改善されている特定の株を同定する方法 |
US9580719B2 (en) | 2007-04-27 | 2017-02-28 | Pfenex, Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
CA2691940C (en) | 2007-07-03 | 2018-03-06 | Joost Alexander Kolkman | Methods for providing improved immunoglobulin sequences |
WO2009026638A1 (en) * | 2007-08-31 | 2009-03-05 | Melbourne Health | Marine-animal derived therapeutic and diagnostic agents for hepatitis b |
AU2009273749B2 (en) | 2008-07-25 | 2016-04-21 | QIAGEN Australia Holding Pty. Ltd. | A diagnostic method |
US20100136584A1 (en) * | 2008-09-22 | 2010-06-03 | Icb International, Inc. | Methods for using antibodies and analogs thereof |
US20100092470A1 (en) * | 2008-09-22 | 2010-04-15 | Icb International, Inc. | Antibodies, analogs and uses thereof |
EP2344545A4 (en) | 2008-10-06 | 2012-10-03 | Commw Scient Ind Res Org | CRYSTALLINE STRUCTURE OF BETA-AMYLOID PEPTIDE |
US9403898B2 (en) | 2009-05-07 | 2016-08-02 | Novozymes Biopharma Dk A/S | Method for purifying albumin |
EP2448966B1 (en) | 2009-07-03 | 2018-11-14 | Avipep Pty Ltd | Immuno-conjugates and methods for producing them |
WO2011056056A2 (es) * | 2009-11-04 | 2011-05-12 | Laboratorios Silanes, S.A. De C.V. | Dominios vhnar anti -citocinas |
ES2735438T3 (es) | 2009-12-23 | 2019-12-18 | Cellestis Ltd | Un ensayo para medir la capacidad de respuesta inmune mediada por células |
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AU2012327878A1 (en) | 2011-10-28 | 2014-05-29 | Patrys Limited | PAT-LM1 epitopes and methods for using same |
US10112988B2 (en) * | 2012-01-09 | 2018-10-30 | Icb International, Inc. | Methods of assessing amyloid-beta peptides in the central nervous system by blood-brain barrier permeable peptide compositions comprising a vab domain of a camelid single domain heavy chain antibody against an anti-amyloid-beta peptide |
US10112987B2 (en) * | 2012-01-09 | 2018-10-30 | Icb International, Inc. | Blood-brain barrier permeable peptide compositions comprising a vab domain of a camelid single domain heavy chain antibody against an amyloid-beta peptide |
CA2863224A1 (en) | 2012-01-09 | 2013-07-18 | The Scripps Research Institute | Ultralong complementarity determining regions and uses thereof |
MX347154B (es) | 2012-02-24 | 2017-02-21 | Centro De Investigación Científica Y De Educación Superior De Ensenada Baja California (Cicese) | Prueba de diagnóstico para enfermedades infecciosas en ganado bovino. |
AU2013257848A1 (en) | 2012-05-07 | 2014-11-27 | The University Court Of The University Of Aberdeen | Single domain binding molecule |
EP2939025B1 (en) | 2012-12-28 | 2018-04-25 | Cellestis Limited | A cell mediated immune response assay |
CN105073781A (zh) | 2013-01-11 | 2015-11-18 | 加州生物医学研究所 | 牛融合抗体 |
EP2762496A1 (en) | 2013-02-05 | 2014-08-06 | EngMab AG | Method for the selection of antibodies against BCMA |
US9963513B2 (en) | 2013-02-05 | 2018-05-08 | Engmab Sàrl | Method for the selection of antibodies against BCMA |
CN117843785A (zh) | 2013-02-07 | 2024-04-09 | Csl有限公司 | Il-11r结合蛋白及其应用 |
EP2789630A1 (en) | 2013-04-09 | 2014-10-15 | EngMab AG | Bispecific antibodies against CD3e and ROR1 |
WO2014173975A1 (en) * | 2013-04-23 | 2014-10-30 | The University Court Of The University Of Aberdeen | Isolation of therapeutic target specific vnar domains to icosl |
RU2718054C2 (ru) | 2013-11-28 | 2020-03-30 | СиЭсЭл ЛИМИТЕД | Способ лечения нефропатии |
KR20160096194A (ko) | 2013-12-18 | 2016-08-12 | 씨에스엘 리미티드 | 상처 치료 방법 |
WO2015100246A1 (en) | 2013-12-24 | 2015-07-02 | Ossianix, Inc. | Baff selective binding compounds and related methods |
WO2015158937A1 (es) | 2014-04-17 | 2015-10-22 | Teraclón Idf, S.L. | ANTICUERPOS MONOCLONALES RECOMBINANTES vNAR NEUTRALIZANTES DEL FACTOR DE CRECIMIENTO DEL ENDOTELIO VASCULAR VEGF |
JP6454981B2 (ja) * | 2014-04-24 | 2019-01-23 | 住友電気工業株式会社 | 半導体積層体および受光素子 |
JP6355020B2 (ja) * | 2014-05-14 | 2018-07-11 | パナソニックIpマネジメント株式会社 | 目元用美容装置 |
EP3160995A2 (en) | 2014-06-26 | 2017-05-03 | Ossianix Inc. | Semi-synthetic nurse shark vnar libraries for making and using selective binding compounds |
AU2015329965A1 (en) | 2014-10-09 | 2017-04-27 | Engmab Sàrl | Bispecific antibodies against CD3epsilon and ROR1 |
AU2015336946A1 (en) | 2014-10-23 | 2017-04-13 | La Trobe University | Fn14-binding proteins and uses thereof |
WO2016065199A1 (en) | 2014-10-23 | 2016-04-28 | Qiagen Sciences, Llc | Peptide composition and uses thereof |
EP3218411B1 (en) | 2014-11-14 | 2022-01-12 | Ossianix, Inc. | Variable new antigen receptors (vnars) directed against transferrin receptor (tfr) and their use |
AU2015367224B2 (en) | 2014-12-19 | 2020-12-10 | Monash University | IL-21 antibodies |
CN114478773A (zh) | 2015-01-09 | 2022-05-13 | 阿达尔塔有限公司 | Cxcr4结合分子 |
WO2016198470A2 (en) | 2015-06-08 | 2016-12-15 | Lophius Biosciences Gmbh | Composition for determination of cell-mediated immune responsiveness |
EP3670535A1 (en) | 2015-08-03 | 2020-06-24 | EngMab Sàrl | Monoclonal antibodies against bcma |
WO2017041143A1 (en) | 2015-09-11 | 2017-03-16 | Ctm@Crc Ltd. | Chimeric antigen receptors and uses thereof |
US10273196B2 (en) | 2015-09-25 | 2019-04-30 | Exxonmobil Chemical Patents Inc. | Hydrocarbon dehydrocyclization |
CN109311968A (zh) | 2016-05-02 | 2019-02-05 | 埃博灵克斯股份有限公司 | 治疗rsv感染 |
CA3034105A1 (en) | 2016-09-23 | 2018-03-29 | Csl Limited | Coagulation factor binding proteins and uses thereof |
CN110167964B (zh) | 2016-11-02 | 2023-12-01 | 百时美施贵宝公司 | 组合用于治疗多发性骨髓瘤的针对bcma和cd3的双特异性抗体和免疫药物 |
CN110325547B (zh) | 2016-11-07 | 2023-12-26 | 德格克斯有限公司 | 新淀粉样蛋白β寡聚体特异性结合分子 |
US11155612B2 (en) | 2017-04-21 | 2021-10-26 | Centro De Investigación Científica Y De Educación Superior De Ensenada, Baja California | vNAR antibody which binds VEGF for use in dogs or cats |
SG10201913144TA (en) | 2017-07-11 | 2020-03-30 | Compass Therapeutics Llc | Agonist antibodies that bind human cd137 and uses thereof |
KR102657978B1 (ko) | 2017-09-27 | 2024-04-16 | 엘라스모겐 리미티드 | 특이적 결합 분자 |
WO2019067015A1 (en) | 2017-09-29 | 2019-04-04 | City Of Hope | RECEPTORS OF CHIMERIC ANTIGENS AND BISPECIFIC ANTIBODIES FOR THE TREATMENT OF COAT CELL LYMPHOMA |
WO2019089753A2 (en) | 2017-10-31 | 2019-05-09 | Compass Therapeutics Llc | Cd137 antibodies and pd-1 antagonists and uses thereof |
US11180544B2 (en) * | 2017-11-07 | 2021-11-23 | City University Of Hong Kong | Method of producing antibody fragment |
EP3713961A2 (en) | 2017-11-20 | 2020-09-30 | Compass Therapeutics LLC | Cd137 antibodies and tumor antigen-targeting antibodies and uses thereof |
WO2019104385A1 (en) | 2017-11-29 | 2019-06-06 | Csl Limited | Method of treating or preventing ischemia-reperfusion injury |
US20210221864A1 (en) | 2018-08-24 | 2021-07-22 | City Of Hope | Masked cytokine conjugates |
MX2021005594A (es) | 2018-11-13 | 2021-10-22 | Compass Therapeutics Llc | Constructos multiespecificos de union contra moleculas de puntos de control y usos de los mismos. |
US20230303654A1 (en) | 2020-08-11 | 2023-09-28 | City Of Hope | Compositions and uses of sars-cov-2 targeted chimeric antigen receptor modified nk cells |
GB202020152D0 (en) | 2020-12-18 | 2021-02-03 | Elasmogen Ltd | Fast-track humanisation of specific binding molecules |
WO2023092177A1 (en) * | 2021-11-23 | 2023-06-01 | Adalta Limited | Rank-l binding molecules |
WO2024008904A2 (en) | 2022-07-08 | 2024-01-11 | Novo Nordisk A/S | Highly potent isvd compounds capable of substituting for fviii(a) |
CN116284423B (zh) * | 2022-12-29 | 2023-10-03 | 江苏百英生物科技有限公司 | 一种靶向条纹斑竹鲨IgNAR-CH1多克隆抗体、其制备方法及其应用 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
WO1990005144A1 (en) | 1988-11-11 | 1990-05-17 | Medical Research Council | Single domain ligands, receptors comprising said ligands, methods for their production, and use of said ligands and receptors |
GB8927230D0 (en) | 1989-12-01 | 1990-01-31 | Unilever Plc | Reagents |
US5955363A (en) | 1990-01-03 | 1999-09-21 | Promega Corporation | Vector for in vitro mutagenesis and use thereof |
ES2162863T3 (es) | 1993-04-29 | 2002-01-16 | Unilever Nv | Produccion de anticuerpos o fragmentos (funcionalizados) de los mismos derivados de inmunoglobulinas de cadena pesada de camelidae. |
EP0739981A1 (en) | 1995-04-25 | 1996-10-30 | Vrije Universiteit Brussel | Variable fragments of immunoglobulins - use for therapeutic or veterinary purposes |
WO1997027213A1 (en) | 1996-01-23 | 1997-07-31 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for screening for transdominant effector peptides and rna molecules |
AUPP221098A0 (en) * | 1998-03-06 | 1998-04-02 | Diatech Pty Ltd | V-like domain binding molecules |
AU747637B2 (en) * | 1998-03-06 | 2002-05-16 | Arana Therapeutics (Vic) Pty Ltd | V-like domain binding molecules |
AU1325102A (en) * | 2000-10-16 | 2002-04-29 | Phylos Inc | Protein scaffolds for antibody mimics and other binding proteins |
EP2277913A3 (en) * | 2001-08-10 | 2012-08-08 | Aberdeen University | Antigen binding domains from fish |
PL208712B1 (pl) * | 2001-08-31 | 2011-05-31 | Avidex Ltd | Rozpuszczalny receptor komórek T (sTCR), rozpuszczalna αβ-postać receptora komórek T (sTCR), wielowartościowy kompleks receptora komórek T (TCR), sposób wykrywania kompleksów MHC-peptyd, środek farmaceutyczny zawierający sTCR i/lub wielowartościowy kompleks TCR, cząsteczka kwasu nukleinowego, wektor, komórka gospodarz, sposób otrzymywania całości lub części łańcucha α TCR albo całości lub części łańcucha β TCR, sposób otrzymywania rozpuszczalnego receptora komórek T (sTCR), sposób otrzymywania rozpuszczalnej αβ-postaci receptora komórek T (sTCR) oraz sposób wykrywania kompleksów MHC-peptyd |
WO2003050531A2 (en) | 2001-12-11 | 2003-06-19 | Algonomics N.V. | Method for displaying loops from immunoglobulin domains in different contexts |
US20040266993A1 (en) * | 2003-06-30 | 2004-12-30 | Evans Glen A. | Non-immunoglobulin binding polypeptides |
-
2005
- 2005-06-02 DK DK10179638.1T patent/DK2330121T3/da active
- 2005-06-02 US US11/628,475 patent/US7977071B2/en active Active
- 2005-06-02 DK DK05744734.4T patent/DK1751181T3/da active
- 2005-06-02 CA CA2567655A patent/CA2567655C/en active Active
- 2005-06-02 WO PCT/AU2005/000789 patent/WO2005118629A1/en active Application Filing
- 2005-06-02 EP EP10179638.1A patent/EP2330121B1/en active Active
- 2005-06-02 AU AU2005250055A patent/AU2005250055B2/en active Active
- 2005-06-02 JP JP2007513617A patent/JP2008511286A/ja active Pending
- 2005-06-02 EP EP05744734A patent/EP1751181B1/en active Active
- 2005-06-02 EP EP10179611A patent/EP2330120A3/en not_active Withdrawn
-
2008
- 2008-09-29 AU AU2008229687A patent/AU2008229687B2/en active Active
-
2009
- 2009-04-28 AU AU2009201692A patent/AU2009201692B2/en active Active
-
2011
- 2011-06-09 US US13/157,205 patent/US20120003214A1/en not_active Abandoned
- 2011-06-10 JP JP2011130413A patent/JP5631812B2/ja not_active Expired - Fee Related
-
2016
- 2016-02-16 US US15/044,731 patent/US20160237169A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2008511286A (ja) | 2008-04-17 |
AU2005250055A1 (en) | 2005-12-15 |
AU2008229687B2 (en) | 2009-01-29 |
JP2011244822A (ja) | 2011-12-08 |
AU2009201692B2 (en) | 2012-08-30 |
CA2567655C (en) | 2015-06-30 |
CA2567655A1 (en) | 2005-12-15 |
EP2330121B1 (en) | 2014-09-03 |
US20160237169A1 (en) | 2016-08-18 |
AU2009201692A1 (en) | 2009-05-21 |
EP1751181A4 (en) | 2008-03-12 |
US7977071B2 (en) | 2011-07-12 |
EP1751181A1 (en) | 2007-02-14 |
EP2330121A3 (en) | 2011-11-16 |
EP2330120A3 (en) | 2011-11-16 |
EP1751181B1 (en) | 2012-08-15 |
US20120003214A1 (en) | 2012-01-05 |
US20090148438A1 (en) | 2009-06-11 |
WO2005118629A1 (en) | 2005-12-15 |
DK2330121T3 (da) | 2014-12-15 |
EP2330121A2 (en) | 2011-06-08 |
AU2008229687A1 (en) | 2008-10-30 |
AU2005250055B2 (en) | 2008-09-11 |
JP5631812B2 (ja) | 2014-11-26 |
EP2330120A2 (en) | 2011-06-08 |
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