DK172690B1 - Analogifremgangsmåde til fremstilling af salte af sulfodehydroabietinsyre eller hydrater deraf - Google Patents
Analogifremgangsmåde til fremstilling af salte af sulfodehydroabietinsyre eller hydrater deraf Download PDFInfo
- Publication number
- DK172690B1 DK172690B1 DK198204675A DK467582A DK172690B1 DK 172690 B1 DK172690 B1 DK 172690B1 DK 198204675 A DK198204675 A DK 198204675A DK 467582 A DK467582 A DK 467582A DK 172690 B1 DK172690 B1 DK 172690B1
- Authority
- DK
- Denmark
- Prior art keywords
- salt
- amine
- acid
- sulfodehydroabietic acid
- sulfodehydroabietic
- Prior art date
Links
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- 238000000034 method Methods 0.000 title claims description 54
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- XGZVUEUWXADBQD-UHFFFAOYSA-L lithium carbonate Chemical compound [Li+].[Li+].[O-]C([O-])=O XGZVUEUWXADBQD-UHFFFAOYSA-L 0.000 description 1
- 229910052808 lithium carbonate Inorganic materials 0.000 description 1
- GLXDVVHUTZTUQK-UHFFFAOYSA-M lithium hydroxide monohydrate Substances [Li+].O.[OH-] GLXDVVHUTZTUQK-UHFFFAOYSA-M 0.000 description 1
- 229940040692 lithium hydroxide monohydrate Drugs 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 159000000003 magnesium salts Chemical class 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 229910001960 metal nitrate Inorganic materials 0.000 description 1
- 229960004452 methionine Drugs 0.000 description 1
- 150000002741 methionine derivatives Chemical class 0.000 description 1
- 239000002395 mineralocorticoid Substances 0.000 description 1
- 150000002780 morpholines Chemical class 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- IOQPZZOEVPZRBK-UHFFFAOYSA-N octan-1-amine Chemical compound CCCCCCCCN IOQPZZOEVPZRBK-UHFFFAOYSA-N 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 229940100692 oral suspension Drugs 0.000 description 1
- 229960003104 ornithine Drugs 0.000 description 1
- 150000004995 p-toluidines Chemical class 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 229940124531 pharmaceutical excipient Drugs 0.000 description 1
- 229940117803 phenethylamine Drugs 0.000 description 1
- DLYUQMMRRRQYAE-UHFFFAOYSA-N phosphorus pentoxide Inorganic materials O1P(O2)(=O)OP3(=O)OP1(=O)OP2(=O)O3 DLYUQMMRRRQYAE-UHFFFAOYSA-N 0.000 description 1
- 229960005141 piperazine Drugs 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- BITYAPCSNKJESK-UHFFFAOYSA-N potassiosodium Chemical compound [Na].[K] BITYAPCSNKJESK-UHFFFAOYSA-N 0.000 description 1
- 235000015497 potassium bicarbonate Nutrition 0.000 description 1
- 229910000028 potassium bicarbonate Inorganic materials 0.000 description 1
- 239000011736 potassium bicarbonate Substances 0.000 description 1
- 229910000027 potassium carbonate Inorganic materials 0.000 description 1
- 235000011181 potassium carbonates Nutrition 0.000 description 1
- TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 description 1
- 229940086066 potassium hydrogencarbonate Drugs 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- OVARTBFNCCXQKS-UHFFFAOYSA-N propan-2-one;hydrate Chemical compound O.CC(C)=O OVARTBFNCCXQKS-UHFFFAOYSA-N 0.000 description 1
- MILWSGRFEGYSGM-UHFFFAOYSA-N propane-1,2-diol;propane-1,2,3-triol Chemical compound CC(O)CO.OCC(O)CO MILWSGRFEGYSGM-UHFFFAOYSA-N 0.000 description 1
- 239000004405 propyl p-hydroxybenzoate Substances 0.000 description 1
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 description 1
- WGYKZJWCGVVSQN-UHFFFAOYSA-N propylamine Chemical class CCCN WGYKZJWCGVVSQN-UHFFFAOYSA-N 0.000 description 1
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- RCVIHORGZULVTN-UHFFFAOYSA-M sodium 8-carboxy-4b,8-dimethyl-2-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthrene-3-sulfonate Chemical compound [Na+].C1CC2C(C)(C(O)=O)CCCC2(C)C2=C1C=C(C(C)C)C(S([O-])(=O)=O)=C2 RCVIHORGZULVTN-UHFFFAOYSA-M 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- ZDQYSKICYIVCPN-UHFFFAOYSA-L sodium succinate (anhydrous) Chemical compound [Na+].[Na+].[O-]C(=O)CCC([O-])=O ZDQYSKICYIVCPN-UHFFFAOYSA-L 0.000 description 1
- 239000001593 sorbitan monooleate Substances 0.000 description 1
- 235000011069 sorbitan monooleate Nutrition 0.000 description 1
- 229940035049 sorbitan monooleate Drugs 0.000 description 1
- CTDQAGUNKPRERK-UHFFFAOYSA-N spirodecane Chemical compound C1CCCC21CCCCC2 CTDQAGUNKPRERK-UHFFFAOYSA-N 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- PXQLVRUNWNTZOS-UHFFFAOYSA-N sulfanyl Chemical class [SH] PXQLVRUNWNTZOS-UHFFFAOYSA-N 0.000 description 1
- 238000006277 sulfonation reaction Methods 0.000 description 1
- 125000000542 sulfonic acid group Chemical group 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 238000011287 therapeutic dose Methods 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 235000013337 tricalcium citrate Nutrition 0.000 description 1
- YNJBWRMUSHSURL-UHFFFAOYSA-N trichloroacetic acid Chemical compound OC(=O)C(Cl)(Cl)Cl YNJBWRMUSHSURL-UHFFFAOYSA-N 0.000 description 1
- UAEJRRZPRZCUBE-UHFFFAOYSA-N trimethoxyalumane Chemical compound [Al+3].[O-]C.[O-]C.[O-]C UAEJRRZPRZCUBE-UHFFFAOYSA-N 0.000 description 1
- 210000002438 upper gastrointestinal tract Anatomy 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/57—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing carboxyl groups bound to the carbon skeleton
- C07C309/58—Carboxylic acid groups or esters thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
- C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB08131856A GB2107584A (en) | 1981-10-22 | 1981-10-22 | Treatment of gastro-intestinal diseases |
| GB8131856 | 1981-10-22 | ||
| GB8218707 | 1982-06-29 | ||
| GB8218707 | 1982-06-29 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK467582A DK467582A (da) | 1983-04-23 |
| DK172690B1 true DK172690B1 (da) | 1999-05-31 |
Family
ID=26281038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK198204675A DK172690B1 (da) | 1981-10-22 | 1982-10-21 | Analogifremgangsmåde til fremstilling af salte af sulfodehydroabietinsyre eller hydrater deraf |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4529602A (xx) |
| EP (1) | EP0078152B1 (xx) |
| JP (1) | JPH02167258A (xx) |
| DE (2) | DE3271037D1 (xx) |
| DK (1) | DK172690B1 (xx) |
| FR (1) | FR2515039A1 (xx) |
| GB (1) | GB2114975B (xx) |
| HK (1) | HK41588A (xx) |
| IT (1) | IT1196554B (xx) |
| SG (1) | SG10788G (xx) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4882271A (en) * | 1988-03-10 | 1989-11-21 | Baylor College Of Medicine | Process for preparation of high molecular weight cell-associated protein of campylobacter pylori and use for serological detection of campylobacter pylori infection |
| USRE34101E (en) * | 1991-03-19 | 1992-10-13 | Baylor College Of Medicine | Process for preparation of high molecular weight cell-associated protein of Campylobacter pylori and use for serological detection of Campylobacter pylori infection |
| IT1262896B (it) * | 1992-03-06 | 1996-07-22 | Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini. | |
| US5336503A (en) * | 1992-03-31 | 1994-08-09 | Daiichi Pharmaceutical Co., Ltd. | Anti-peptic ulcer agent |
| JP3059092B2 (ja) * | 1995-11-15 | 2000-07-04 | 田辺製薬株式会社 | ドライアイおよびドライアイを原因とする疾患の予防・治療剤 |
| TW585762B (en) | 1999-11-11 | 2004-05-01 | Tanabe Seiyaku Co | Pharmaceutical composition for prophylaxis or treatment of inflammatory bowel diseases |
| US20030099703A1 (en) * | 2000-08-11 | 2003-05-29 | Shigeru Aoki | Drug-containing solid dispersion having improved solubility |
| FI20010233A0 (fi) * | 2001-02-08 | 2001-02-08 | Orion Corp | Menetelmä sydämen vajaatoiminnan hoitoon |
| US7249242B2 (en) | 2002-10-28 | 2007-07-24 | Nvidia Corporation | Input pipeline registers for a node in an adaptive computing engine |
| US7752419B1 (en) | 2001-03-22 | 2010-07-06 | Qst Holdings, Llc | Method and system for managing hardware resources to implement system functions using an adaptive computing architecture |
| KR20030092073A (ko) * | 2001-04-17 | 2003-12-03 | 다나베 세이야꾸 가부시키가이샤 | 구강 점막 등에서의 염증성 질환의 예방/치료제 |
| CN1219757C (zh) * | 2001-07-16 | 2005-09-21 | 中国医药研究开发中心有限公司 | 磺化去氢松香酸盐及其制备方法和其用途 |
| AU2002338038B2 (en) * | 2001-09-27 | 2005-08-18 | Tanabe Seiyaku Co., Ltd. | Aqueous ecabet sodium solution preparation |
| US7046635B2 (en) | 2001-11-28 | 2006-05-16 | Quicksilver Technology, Inc. | System for authorizing functionality in adaptable hardware devices |
| CN101590031B (zh) * | 2008-06-17 | 2011-10-12 | 浙江爱生药业有限公司 | 磺化去氢松香酸二钠组合物的制备方法 |
| FI124101B (en) | 2012-05-14 | 2014-03-14 | Hankkija Maatalous Oy | Modified tall oil fatty acid |
| FI124918B (fi) | 2013-05-14 | 2015-03-31 | Hankkija Maatalous Oy | Mäntyöljyrasvahappo |
| FI125051B (fi) | 2013-10-24 | 2015-05-15 | Hankkija Oy | Mäntyöljyrasvahappo |
| ES2809680T3 (es) * | 2013-11-13 | 2021-03-05 | Hankkija Oy | Complemento alimenticio que comprende ácidos resínicos |
| CN103772241B (zh) * | 2014-01-07 | 2015-08-26 | 珠海亿邦制药股份有限公司 | 一种磺化去氢松香酸盐的制备方法 |
| CN104447432B (zh) * | 2014-11-21 | 2018-01-26 | 珠海亿邦制药股份有限公司 | 一种新的磺化去氢松香酸铋的制备方法 |
| US10248420B2 (en) | 2017-04-05 | 2019-04-02 | Cavium, Llc | Managing lock and unlock operations using active spinning |
| WO2019089498A1 (en) * | 2017-10-30 | 2019-05-09 | Theracaine Llc | Hydrophobic ammonium and phosphonium salts |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2121032A (en) * | 1936-03-24 | 1938-06-21 | G & A Lab | Detergent and wetting agent and process of producing the same |
| FR2481270A1 (fr) * | 1980-04-24 | 1981-10-30 | Roussel Uclaf | Nouveaux derives substitues de l'acide 4-phenyl 4-oxo 2-hydroxy butanoique, procede pour leur preparation et applications comme medicaments |
-
1982
- 1982-10-21 GB GB08230027A patent/GB2114975B/en not_active Expired
- 1982-10-21 EP EP82305594A patent/EP0078152B1/en not_active Expired
- 1982-10-21 DK DK198204675A patent/DK172690B1/da active
- 1982-10-21 DE DE8282305594T patent/DE3271037D1/de not_active Expired
- 1982-10-21 IT IT49332/82A patent/IT1196554B/it active
- 1982-10-22 FR FR8217722A patent/FR2515039A1/fr active Granted
- 1982-10-22 DE DE19823239172 patent/DE3239172A1/de not_active Withdrawn
-
1984
- 1984-06-14 US US06/621,124 patent/US4529602A/en not_active Expired - Lifetime
-
1988
- 1988-02-06 SG SG107/88A patent/SG10788G/en unknown
- 1988-06-02 HK HK415/88A patent/HK41588A/xx not_active IP Right Cessation
-
1989
- 1989-10-19 JP JP1273358A patent/JPH02167258A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| US4529602A (en) | 1985-07-16 |
| JPH02167258A (ja) | 1990-06-27 |
| GB2114975A (en) | 1983-09-01 |
| SG10788G (en) | 1988-07-01 |
| FR2515039B1 (xx) | 1985-03-22 |
| DK467582A (da) | 1983-04-23 |
| EP0078152B1 (en) | 1986-05-07 |
| JPH0451546B2 (xx) | 1992-08-19 |
| HK41588A (en) | 1988-06-10 |
| IT1196554B (it) | 1988-11-16 |
| FR2515039A1 (fr) | 1983-04-29 |
| IT8249332A0 (it) | 1982-10-21 |
| GB2114975B (en) | 1985-06-05 |
| DE3271037D1 (en) | 1986-06-12 |
| EP0078152A1 (en) | 1983-05-04 |
| DE3239172A1 (de) | 1983-05-05 |
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