DK171711B1 - Inhibin isoleret fra mammal ovariefollikelvæske, monoklonalt eller polyklonalt antistofpræparat, immunoassay for inhibin, og rensning af inhibin, og radio- eller enzymbundet immunoassay for inhibin - Google Patents

Inhibin isoleret fra mammal ovariefollikelvæske, monoklonalt eller polyklonalt antistofpræparat, immunoassay for inhibin, og rensning af inhibin, og radio- eller enzymbundet immunoassay for inhibin Download PDF

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Publication number
DK171711B1
DK171711B1 DK060586A DK60586A DK171711B1 DK 171711 B1 DK171711 B1 DK 171711B1 DK 060586 A DK060586 A DK 060586A DK 60586 A DK60586 A DK 60586A DK 171711 B1 DK171711 B1 DK 171711B1
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DK
Denmark
Prior art keywords
inhibin
protein
antibody
purified
sds
Prior art date
Application number
DK060586A
Other languages
Danish (da)
English (en)
Other versions
DK60586A (da
DK60586D0 (da
Inventor
David Moritz De Kretser
Milton Thomas William Hearn
Henry George Burger
John Kerr Findlay
Francis Joseph Morgan
David Mark Robertson
Robert Gregory Forage
Richard Esward Hugh Wettenhall
Original Assignee
Biotech Australia Pty Ltd
Univ Monash
St Vincents Inst Med Res
Monash Medical Centre
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotech Australia Pty Ltd, Univ Monash, St Vincents Inst Med Res, Monash Medical Centre filed Critical Biotech Australia Pty Ltd
Publication of DK60586A publication Critical patent/DK60586A/da
Publication of DK60586D0 publication Critical patent/DK60586D0/da
Application granted granted Critical
Publication of DK171711B1 publication Critical patent/DK171711B1/da

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/817—Steroids or hormones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806—Antigenic peptides or proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/85—Reproductive organs or embryos

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Pregnancy & Childbirth (AREA)
  • Food Science & Technology (AREA)
  • Reproductive Health (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Networks Using Active Elements (AREA)
  • Centrifugal Separators (AREA)
DK060586A 1984-06-08 1986-02-07 Inhibin isoleret fra mammal ovariefollikelvæske, monoklonalt eller polyklonalt antistofpræparat, immunoassay for inhibin, og rensning af inhibin, og radio- eller enzymbundet immunoassay for inhibin DK171711B1 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
AUPG542784 1984-06-08
AUPG542784 1984-06-08
AUPH003185 1985-04-04
AUPH003185 1985-04-04
PCT/AU1985/000119 WO1986000078A1 (en) 1984-06-08 1985-06-03 Inhibin isolated from ovarian follicular fluid
AU8500119 1985-06-03

Publications (3)

Publication Number Publication Date
DK60586A DK60586A (da) 1986-02-07
DK60586D0 DK60586D0 (da) 1986-02-07
DK171711B1 true DK171711B1 (da) 1997-04-01

Family

ID=25642809

Family Applications (1)

Application Number Title Priority Date Filing Date
DK060586A DK171711B1 (da) 1984-06-08 1986-02-07 Inhibin isoleret fra mammal ovariefollikelvæske, monoklonalt eller polyklonalt antistofpræparat, immunoassay for inhibin, og rensning af inhibin, og radio- eller enzymbundet immunoassay for inhibin

Country Status (10)

Country Link
US (2) US5102807A (https=)
EP (1) EP0185034B1 (https=)
JP (2) JP2521707B2 (https=)
AT (1) ATE95194T1 (https=)
CA (1) CA1341617C (https=)
DE (1) DE3587603T2 (https=)
DK (1) DK171711B1 (https=)
NO (1) NO176570C (https=)
NZ (1) NZ212248A (https=)
WO (1) WO1986000078A1 (https=)

Families Citing this family (41)

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CA1341617C (en) * 1984-06-08 2011-06-28 Henry George Burger Inhibin isolated from ovarian follicular fluid
EP0218717B1 (en) * 1985-04-18 1998-07-15 Biotechnology Australia Pty. Ltd. Recombinant inhibin
NZ217727A (en) * 1985-10-03 1990-05-28 Genentech Inc Nucleic acid encoding alpha or b chain of inhibin, its production and compositions containing it
US4798885A (en) * 1986-02-07 1989-01-17 Genentech, Inc. Compositions of hormonally active human and porcine inhibin containing an α chain and 62 chain
US5215893A (en) * 1985-10-03 1993-06-01 Genentech, Inc. Nucleic acid encoding the ba chain prodomains of inhibin and method for synthesizing polypeptides using such nucleic acid
US5089396A (en) * 1985-10-03 1992-02-18 Genentech, Inc. Nucleic acid encoding β chain prodomains of inhibin and method for synthesizing polypeptides using such nucleic acid
US4864019A (en) * 1985-11-08 1989-09-05 The Salk Institute For Biological Studies Antibodies to inhibin and conjugates produced therefrom
AU599373B2 (en) * 1986-03-13 1990-07-19 Biotechnology Australia Proprietary Limited Method of assay of inhibin
US5015729A (en) * 1986-06-24 1991-05-14 The Salk Institute For Biological Studies Ovine inhibin
US6150328A (en) * 1986-07-01 2000-11-21 Genetics Institute, Inc. BMP products
ATE120209T1 (de) * 1987-01-29 1995-04-15 Biotech Australia Pty Ltd Isolierung von einkettigen proteinen mit fsh unter- drückender aktivität aus follikularflüssigkeit.
US5032507A (en) * 1987-11-13 1991-07-16 The Salk Institute For Biological Studies Potentiation of erythropoiesis
EP0368992B1 (en) * 1988-05-31 1995-02-15 Biotechnology Australia Pty. Ltd. Actions of hormones
EP0509040B1 (en) * 1990-01-08 1994-11-09 Genentech, Inc. Method for increasing fertility in females
DE4042408C2 (de) * 1990-01-08 1995-04-06 Stefan Heiden Verwendung von Inhibin- neutralisierenden Antikörpern
US5942220A (en) * 1990-03-16 1999-08-24 Chiron Corporation Inhibitor of cytokine activity and applications thereof
ATE238417T1 (de) * 1991-11-04 2003-05-15 Inst Genetics Llc Rekombinante knochenmorphogenetische protein heterodimere, zusammensetzungen und verfahren zur verwendung
US20080139474A1 (en) * 1991-11-04 2008-06-12 David Israel Recombinant bone morphogenetic protein heterodimers, compositions and methods of use
US5428011A (en) * 1992-06-16 1995-06-27 Procyon Biopharma, Inc. Pharmaceutical preparations for inhibiting tumours associated with prostate adenocarcinoma
BR9406715A (pt) * 1993-05-12 1996-02-06 Genetics Inst Molécula de DNA isolada célula hospedeira vetor método para produzir uma proteina (BMP-11) polipeptideo de proteina-11 morfogenética de osso purificada (BMP-11) e molécula de DNA quimérica
US6291206B1 (en) * 1993-09-17 2001-09-18 Genetics Institute, Inc. BMP receptor proteins
DE69434651T2 (de) 1993-12-07 2007-03-08 Genetics Institute, Inc., Cambridge Bmp-12, bmp-13 und diese enthaltende sehne-induzierende zusammensetzungen
US5786179A (en) * 1994-02-28 1998-07-28 Agritech Technologies Ltd. Heterologous protein comprising avian alpha-subunit inhibin protein and methods of producing same
US5747659A (en) * 1994-02-28 1998-05-05 Agritech Technologies, Ltd. Fusion gene products encoding avian alpha subunit inhibin protein, or an immunogenic fragment thereof, and a carrier protein
US20030171283A1 (en) * 1994-02-28 2003-09-11 Satterlee Daniel G. Inhibin compositions and methods of enhancing production performance
AU780982B2 (en) * 1997-04-23 2005-04-28 Monash University Inhibin modulation of cell growth
AUPO638897A0 (en) * 1997-04-23 1997-05-22 Monash University Modulation of cell growth and methods relating thereto
TW586934B (en) * 1997-05-19 2004-05-11 Sumitomo Pharma Immunopotentiating composition
US6727224B1 (en) * 1999-02-01 2004-04-27 Genetics Institute, Llc. Methods and compositions for healing and repair of articular cartilage
PT1223990E (pt) 1999-10-15 2004-12-31 Fidia Advanced Biopolymers Srl Formulacoes de acido hialuronico para administracao de proteinas osteogenicas
CA2355334A1 (en) * 2000-10-16 2002-04-16 Procyon Biopharma Inc. Pharmaceutical preparations and methods for inhibiting tumors
US20030082233A1 (en) * 2000-12-01 2003-05-01 Lyons Karen M. Method and composition for modulating bone growth
TWI329129B (en) * 2001-02-08 2010-08-21 Wyeth Corp Modified and stabilized gdf propeptides and uses thereof
EP1399023B1 (en) * 2001-06-01 2008-04-30 Wyeth COMPOSITIONS FOR SYSTEMIC ADMINISTRATION OF SEQUENCES ENCODING BONE MORPHOGENETIC PROTEINS& x9;
TWI267378B (en) * 2001-06-08 2006-12-01 Wyeth Corp Calcium phosphate delivery vehicles for osteoinductive proteins
US20050026833A1 (en) * 2001-11-08 2005-02-03 Rabbani Shafaat Ahmed PSP-94: use for treatment of hypercalcemia and bone metastasis
BR0310087A (pt) * 2002-05-17 2005-08-16 Wyeth Corp Veìculos sólidos injetáveis para ácido hialurÈnico para aplicação de proteìnas osteogênicas
AU2003297254A1 (en) * 2002-11-07 2004-06-03 Agritech Technology, Ltd Novel compositions that enhance production performance in avians
AU2004272072B2 (en) * 2003-09-12 2010-07-08 Etex Corporation Injectable calcium phosphate solid rods and pastes for delivery of osteogenic proteins
ES2667013T3 (es) 2010-11-29 2018-05-09 Mote Marine Laboratory, Inc. Determinación de las características sexuales de peces usando hormonas peptídicas
BR102014005376A2 (pt) * 2014-03-07 2016-02-10 Ouro Fino Saúde Animal Ltda antígeno de inibina alfa, gene codificante de inibina alfa, gene codificante de proteína de fusão, processo de obtenção do antígeno de inibina alfa, composição antigênica, uso do antígeno de inibina alfa e uso da composição antigênica

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FR2361912A1 (fr) * 1976-08-19 1978-03-17 Merck & Co Inc Vaccin anti-fecondite a base de membrane pellucide solubilisee
US4409139A (en) * 1981-08-10 1983-10-11 The Salk Institute For Biological Studies Gonadostatin
US4423037A (en) * 1982-05-13 1983-12-27 The General Hospital Corporation Inhibitors of peptide hormone action
CA1341617C (en) * 1984-06-08 2011-06-28 Henry George Burger Inhibin isolated from ovarian follicular fluid
EP0218717B1 (en) * 1985-04-18 1998-07-15 Biotechnology Australia Pty. Ltd. Recombinant inhibin
US4624944A (en) * 1985-06-14 1986-11-25 The Regents Of The University Of California Human seminal alpha-inhibins
US4740587A (en) * 1985-07-18 1988-04-26 The Salk Institute For Biological Studies Inhibin and method of purifying same
US4798885A (en) * 1986-02-07 1989-01-17 Genentech, Inc. Compositions of hormonally active human and porcine inhibin containing an α chain and 62 chain
US4864019A (en) * 1985-11-08 1989-09-05 The Salk Institute For Biological Studies Antibodies to inhibin and conjugates produced therefrom
US4737578A (en) * 1986-02-10 1988-04-12 The Salk Institute For Biological Studies Human inhibin
EP0368992B1 (en) * 1988-05-31 1995-02-15 Biotechnology Australia Pty. Ltd. Actions of hormones

Also Published As

Publication number Publication date
JPS61502399A (ja) 1986-10-23
EP0185034B1 (en) 1993-09-29
JP2583030B2 (ja) 1997-02-19
NO860427L (no) 1986-02-06
NO176570B (no) 1995-01-16
DE3587603D1 (de) 1993-11-04
JPH0848636A (ja) 1996-02-20
US5364837A (en) 1994-11-15
DK60586A (da) 1986-02-07
DE3587603T2 (de) 1994-02-10
US5102807A (en) 1992-04-07
ATE95194T1 (de) 1993-10-15
CA1341617C (en) 2011-06-28
DK60586D0 (da) 1986-02-07
NZ212248A (en) 1991-05-28
JP2521707B2 (ja) 1996-08-07
EP0185034A4 (https=) 1988-01-28
NO176570C (no) 1995-04-26
EP0185034A1 (https=) 1986-06-25
WO1986000078A1 (en) 1986-01-03

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment
AHB Application shelved due to non-payment
B1 Patent granted (law 1993)
PUP Patent expired