DK170799B1 - 7-[[3-Aminomethyl)-3-alkyl]-1-pyrrolidinyl]-quinolin- og -naphthyridin-derivater, farmaceutisk præparat indeholdende en sådan forbindelse og fremgangsmåde til fremstilling af sådanne forbindelser, samt pyrrolidinderivater med mellemproduktanvendelse - Google Patents

7-[[3-Aminomethyl)-3-alkyl]-1-pyrrolidinyl]-quinolin- og -naphthyridin-derivater, farmaceutisk præparat indeholdende en sådan forbindelse og fremgangsmåde til fremstilling af sådanne forbindelser, samt pyrrolidinderivater med mellemproduktanvendelse Download PDF

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Publication number
DK170799B1
DK170799B1 DK390587A DK390587A DK170799B1 DK 170799 B1 DK170799 B1 DK 170799B1 DK 390587 A DK390587 A DK 390587A DK 390587 A DK390587 A DK 390587A DK 170799 B1 DK170799 B1 DK 170799B1
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Prior art keywords
methyl
acid
pyrrolidinyl
aminomethyl
oxo
Prior art date
Application number
DK390587A
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Danish (da)
English (en)
Other versions
DK390587D0 (da
DK390587A (da
Inventor
John Michael Domagala
Susan Elizabeth Hagen
Joseph Peter Sanchez
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Warner Lambert Co
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Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of DK390587D0 publication Critical patent/DK390587D0/da
Publication of DK390587A publication Critical patent/DK390587A/da
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Publication of DK170799B1 publication Critical patent/DK170799B1/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyrrole Compounds (AREA)
DK390587A 1986-07-28 1987-07-27 7-[[3-Aminomethyl)-3-alkyl]-1-pyrrolidinyl]-quinolin- og -naphthyridin-derivater, farmaceutisk præparat indeholdende en sådan forbindelse og fremgangsmåde til fremstilling af sådanne forbindelser, samt pyrrolidinderivater med mellemproduktanvendelse DK170799B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US88999486A 1986-07-28 1986-07-28
US88999486 1986-07-28
US07/039,438 US4771055A (en) 1986-07-28 1987-04-21 7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-quinoline-carboxylic acids
US3943887 1987-04-21

Publications (3)

Publication Number Publication Date
DK390587D0 DK390587D0 (da) 1987-07-27
DK390587A DK390587A (da) 1988-01-29
DK170799B1 true DK170799B1 (da) 1996-01-22

Family

ID=26716130

Family Applications (1)

Application Number Title Priority Date Filing Date
DK390587A DK170799B1 (da) 1986-07-28 1987-07-27 7-[[3-Aminomethyl)-3-alkyl]-1-pyrrolidinyl]-quinolin- og -naphthyridin-derivater, farmaceutisk præparat indeholdende en sådan forbindelse og fremgangsmåde til fremstilling af sådanne forbindelser, samt pyrrolidinderivater med mellemproduktanvendelse

Country Status (14)

Country Link
US (1) US4771055A (no)
EP (1) EP0255908B1 (no)
JP (2) JPH082896B2 (no)
KR (1) KR950008050B1 (no)
AT (1) ATE113043T1 (no)
AU (1) AU595631B2 (no)
CA (1) CA1324141C (no)
DE (1) DE3750668D1 (no)
DK (1) DK170799B1 (no)
FI (1) FI873248A (no)
NO (1) NO873125L (no)
NZ (1) NZ221021A (no)
PH (1) PH24681A (no)
PT (1) PT85411B (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4822801A (en) * 1984-07-20 1989-04-18 Warner-Lambert Company 4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivative as antibacterial agents
EP0242789A3 (en) * 1986-04-25 1990-09-05 Dainippon Pharmaceutical Co., Ltd. Novel quinoline derivates and processes for preparation thereof
US5563138A (en) * 1987-04-16 1996-10-08 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
US5173484A (en) * 1988-02-05 1992-12-22 Bayer Aktiengesellschaft Quinolone- and naphthyridone carboxylic acid derivatives, process for their production, antibacterial compositions and feed additives containing them
DE3814517A1 (de) * 1988-02-05 1989-08-17 Bayer Ag Chinolon- und naphthyridoncarbonsaeurederivate, verfahren zu ihrer herstellung und sie enthaltende antibakterielle mittel und futterzusatzstoffe
ES2070142T3 (es) * 1988-05-19 1995-06-01 Chugai Pharmaceutical Co Ltd Nuevos derivados del acido quinolonacarboxilico.
US5039682A (en) * 1988-06-21 1991-08-13 Pfizer Inc. 6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acid derivatives and intermediates therefor
US5233091A (en) * 1988-06-21 1993-08-03 Pfizer Inc. 6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acid derivatives and intermediates therefor
US5104868A (en) * 1988-06-21 1992-04-14 Pfizer Inc. Tricyclic derivatives of 7-substituted-6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acids and esters
JPH0674261B2 (ja) * 1988-06-21 1994-09-21 塩野義製薬株式会社 キノロンカルボン酸誘導体
US5103040A (en) * 1988-06-21 1992-04-07 Pfizer Inc. 6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acid derivatives and intermediates therefor
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
CA1332605C (en) * 1988-10-03 1994-10-18 Yasuhiro Nishitani Pyridonecarboxylic acids
ATE193890T1 (de) 1990-04-18 2000-06-15 Procter & Gamble Pharma Antimikrobielle chinolonyl-lactame
DE4104870A1 (de) * 1991-02-17 1992-08-27 Bayer Ag Verwendung von 3,(4)-substituierten pyrrolidinen als katalysatoren fuer das polyisocyanatpolyadditionsverfahren, verfahren zu ihrer herstellung sowie verfahren zur herstellung von polyurethan(harnstoff)en
TW252107B (no) * 1993-08-27 1995-07-21 Hokuriku Pharmacetical Co Ltd
EP0806421A4 (en) * 1995-01-24 1998-04-15 Hokuriku Pharmaceutical DERIVATIVES OF CHINOLINE CARBONIC ACID
ES2224235T3 (es) 1996-04-19 2005-03-01 Wakunaga Pharmaceutical Co., Ltd. Nuevos derivados del acido piridonacarboxilico o sus sales y agentes antibacterianos que contienen los mismos como ingredientes activos.
TW425394B (en) * 1996-04-24 2001-03-11 Daiichi Seiyaku Co Antimicrobial quinolone derivatives having 3-(N-cycloalkyl) aminomethylpyrrolidine group
CN100410249C (zh) * 2003-09-10 2008-08-13 杏林制药株式会社 7-(4-取代-3-环丙基氨基甲基-1-吡咯烷基)喹诺酮羧酸衍生物
US8222407B2 (en) * 2007-05-24 2012-07-17 Kyorin Pharmaceutical Co., Ltd. Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4665079A (en) * 1984-02-17 1987-05-12 Warner-Lambert Company Antibacterial agents
IE55898B1 (en) * 1982-09-09 1991-02-14 Warner Lambert Co Antibacterial agents
NZ208470A (en) * 1983-07-18 1988-06-30 Abbott Lab 6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid derivatives and antibacterial compositions containing such
CS274601B2 (en) * 1983-07-27 1991-09-15 Dainippon Pharmaceutical Co Method of 1,8-naphthyridine derivative production
DE3577089D1 (de) * 1984-01-26 1990-05-17 Abbott Lab Antibakterielle chinolinderivate.
DE3420743A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-dihalogen-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
IE58742B1 (en) * 1984-07-20 1993-11-05 Warner Lambert Co Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
JPH0670032B2 (ja) * 1984-11-22 1994-09-07 大日本製薬株式会社 アミノピロリジン誘導体、そのエステルおよびその塩

Also Published As

Publication number Publication date
NZ221021A (en) 1991-06-25
JPH082896B2 (ja) 1996-01-17
NO873125D0 (no) 1987-07-27
EP0255908A2 (en) 1988-02-17
PH24681A (en) 1990-09-07
EP0255908A3 (en) 1989-10-25
JP2628541B2 (ja) 1997-07-09
AU7608387A (en) 1988-02-04
JPH08169876A (ja) 1996-07-02
KR880001633A (ko) 1988-04-25
ATE113043T1 (de) 1994-11-15
KR950008050B1 (ko) 1995-07-24
EP0255908B1 (en) 1994-10-19
JPS6379885A (ja) 1988-04-09
AU595631B2 (en) 1990-04-05
DE3750668D1 (de) 1994-11-24
PT85411B (pt) 1990-06-29
US4771055A (en) 1988-09-13
FI873248A (fi) 1988-01-29
DK390587D0 (da) 1987-07-27
FI873248A0 (fi) 1987-07-24
DK390587A (da) 1988-01-29
NO873125L (no) 1988-01-29
PT85411A (en) 1987-08-01
CA1324141C (en) 1993-11-09

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