DK1701942T3 - Inhibitorer for ikke-nukleotid revers transkriptase - Google Patents

Inhibitorer for ikke-nukleotid revers transkriptase

Info

Publication number
DK1701942T3
DK1701942T3 DK04809207.6T DK04809207T DK1701942T3 DK 1701942 T3 DK1701942 T3 DK 1701942T3 DK 04809207 T DK04809207 T DK 04809207T DK 1701942 T3 DK1701942 T3 DK 1701942T3
Authority
DK
Denmark
Prior art keywords
alkyl
orx
nrxrx
reverse transcriptase
transcriptase inhibitors
Prior art date
Application number
DK04809207.6T
Other languages
Danish (da)
English (en)
Inventor
Christian Sund
Nathalie Roue
Stefan Lindstroem
Dmitry Antonov
Christer Sahlberg
Katarina Jansson
Original Assignee
Medivir Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0400021A external-priority patent/SE0400021D0/xx
Priority claimed from SE0400585A external-priority patent/SE0400585D0/xx
Application filed by Medivir Ab filed Critical Medivir Ab
Application granted granted Critical
Publication of DK1701942T3 publication Critical patent/DK1701942T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK04809207.6T 2004-01-08 2004-12-30 Inhibitorer for ikke-nukleotid revers transkriptase DK1701942T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0400021A SE0400021D0 (sv) 2004-01-08 2004-01-08 Non-nucleoside reverse transcriptase inhibitors
SE0400585A SE0400585D0 (sv) 2004-03-09 2004-03-09 NNRTI Antivirals
PCT/SE2004/002034 WO2005066131A1 (en) 2004-01-08 2004-12-30 Non-nucleotide reverse transcriptase inhibitors

Publications (1)

Publication Number Publication Date
DK1701942T3 true DK1701942T3 (da) 2010-04-06

Family

ID=34752289

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04809207.6T DK1701942T3 (da) 2004-01-08 2004-12-30 Inhibitorer for ikke-nukleotid revers transkriptase

Country Status (15)

Country Link
US (1) US7915295B2 (https=)
EP (1) EP1701942B1 (https=)
JP (1) JP4762917B2 (https=)
AT (1) ATE451357T1 (https=)
AU (1) AU2004312284B2 (https=)
BR (1) BRPI0418306B8 (https=)
CA (1) CA2550187C (https=)
DE (1) DE602004024584D1 (https=)
DK (1) DK1701942T3 (https=)
EA (1) EA009700B1 (https=)
ES (1) ES2337794T3 (https=)
IL (1) IL176740A (https=)
NZ (1) NZ548367A (https=)
SG (1) SG149070A1 (https=)
WO (1) WO2005066131A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1534276B1 (en) * 2002-09-05 2008-11-05 Medivir AB Non-nucleoside reverse transcriptase inhibitors
US7388008B2 (en) 2004-08-02 2008-06-17 Ambrilia Biopharma Inc. Lysine based compounds
ES2539527T3 (es) * 2005-04-27 2015-07-01 Taimed Biologics, Inc. Método para mejorar la farmacocinética de los inhibidores de las proteasas y de los precursores de los inhibidores de las proteasas
CN101405293B (zh) 2005-11-30 2013-03-13 中裕新药股份有限公司 天冬氨酰基蛋白酶抑制剂基于赖氨酸的前体药物及其制备方法
GB0608876D0 (en) 2006-05-05 2006-06-14 Medivir Ab Combination therapy
ATE552245T1 (de) 2006-05-15 2012-04-15 Merck Sharp & Dohme Antidiabetische bicyclische verbindungen
US8410300B2 (en) 2006-09-21 2013-04-02 Taimed Biologics, Inc. Protease inhibitors
WO2016123387A1 (en) * 2015-01-30 2016-08-04 Genentech, Inc. Therapeutic compounds and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9906933A (pt) * 1998-01-16 2001-11-27 Medivir Ab Antiviróticos
WO1999051613A1 (en) * 1998-04-03 1999-10-14 Medivir Ab Prodrugs of phosphorous-containing pharmaceuticals
SE0100733D0 (sv) * 2001-03-05 2001-03-05 Medivir Ab Non-nucleoside reverse transcriptase inhibitors
SE0102867D0 (sv) * 2001-08-28 2001-08-28 Medivir Ab Non-nucleoside reverse transcriptase inhibitors
EP1534276B1 (en) * 2002-09-05 2008-11-05 Medivir AB Non-nucleoside reverse transcriptase inhibitors

Also Published As

Publication number Publication date
EA009700B1 (ru) 2008-02-28
EP1701942A1 (en) 2006-09-20
BRPI0418306A (pt) 2007-05-02
JP2007519640A (ja) 2007-07-19
AU2004312284B2 (en) 2010-08-05
AU2004312284A1 (en) 2005-07-21
CA2550187C (en) 2012-08-07
JP4762917B2 (ja) 2011-08-31
IL176740A (en) 2011-09-27
AU2004312284A2 (en) 2005-07-21
WO2005066131A1 (en) 2005-07-21
BRPI0418306B1 (pt) 2018-09-18
ATE451357T1 (de) 2009-12-15
DE602004024584D1 (de) 2010-01-21
HK1101400A1 (en) 2007-10-18
EA200601289A1 (ru) 2006-12-29
US7915295B2 (en) 2011-03-29
NZ548367A (en) 2010-06-25
ES2337794T3 (es) 2010-04-29
CA2550187A1 (en) 2005-07-21
SG149070A1 (en) 2009-01-29
BRPI0418306B8 (pt) 2021-05-25
US20080070951A1 (en) 2008-03-20
IL176740A0 (en) 2006-10-31
EP1701942B1 (en) 2009-12-09

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