DK1701942T3 - Inhibitorer for ikke-nukleotid revers transkriptase - Google Patents

Inhibitorer for ikke-nukleotid revers transkriptase

Info

Publication number
DK1701942T3
DK1701942T3 DK04809207.6T DK04809207T DK1701942T3 DK 1701942 T3 DK1701942 T3 DK 1701942T3 DK 04809207 T DK04809207 T DK 04809207T DK 1701942 T3 DK1701942 T3 DK 1701942T3
Authority
DK
Denmark
Prior art keywords
alkyl
orx
nrxrx
reverse transcriptase
transcriptase inhibitors
Prior art date
Application number
DK04809207.6T
Other languages
Danish (da)
English (en)
Inventor
Christian Sund
Nathalie Roue
Stefan Lindstroem
Dmitry Antonov
Christer Sahlberg
Katarina Jansson
Original Assignee
Medivir Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0400021A external-priority patent/SE0400021D0/xx
Priority claimed from SE0400585A external-priority patent/SE0400585D0/xx
Application filed by Medivir Ab filed Critical Medivir Ab
Application granted granted Critical
Publication of DK1701942T3 publication Critical patent/DK1701942T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK04809207.6T 2004-01-08 2004-12-30 Inhibitorer for ikke-nukleotid revers transkriptase DK1701942T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0400021A SE0400021D0 (sv) 2004-01-08 2004-01-08 Non-nucleoside reverse transcriptase inhibitors
SE0400585A SE0400585D0 (sv) 2004-03-09 2004-03-09 NNRTI Antivirals
PCT/SE2004/002034 WO2005066131A1 (en) 2004-01-08 2004-12-30 Non-nucleotide reverse transcriptase inhibitors

Publications (1)

Publication Number Publication Date
DK1701942T3 true DK1701942T3 (da) 2010-04-06

Family

ID=34752289

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04809207.6T DK1701942T3 (da) 2004-01-08 2004-12-30 Inhibitorer for ikke-nukleotid revers transkriptase

Country Status (15)

Country Link
US (1) US7915295B2 (enExample)
EP (1) EP1701942B1 (enExample)
JP (1) JP4762917B2 (enExample)
AT (1) ATE451357T1 (enExample)
AU (1) AU2004312284B2 (enExample)
BR (1) BRPI0418306B8 (enExample)
CA (1) CA2550187C (enExample)
DE (1) DE602004024584D1 (enExample)
DK (1) DK1701942T3 (enExample)
EA (1) EA009700B1 (enExample)
ES (1) ES2337794T3 (enExample)
IL (1) IL176740A (enExample)
NZ (1) NZ548367A (enExample)
SG (1) SG149070A1 (enExample)
WO (1) WO2005066131A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20050033663A (ko) * 2002-09-05 2005-04-12 메디비르 아베 비-뉴클레오시드 역전사효소 억제제
US7388008B2 (en) 2004-08-02 2008-06-17 Ambrilia Biopharma Inc. Lysine based compounds
US20060287316A1 (en) * 2005-04-27 2006-12-21 Ambrilia Biopharma Inc. Method for improving pharmacokinetics of protease inhibitors and protease inhibitor precursors
WO2007062526A1 (en) 2005-11-30 2007-06-07 Ambrilia Biopharma Inc. Lysine-based prodrugs of aspartyl protease inhibitors and processes for their preparation
GB0608876D0 (en) * 2006-05-05 2006-06-14 Medivir Ab Combination therapy
AU2007254325B2 (en) * 2006-05-15 2012-05-10 Merck Sharp & Dohme Corp. Antidiabetic bicyclic compounds
ES2628730T3 (es) 2006-09-21 2017-08-03 Taimed Biologics, Inc. Inhibidores de proteasa
EP3250552B1 (en) * 2015-01-30 2019-03-27 Genentech, Inc. Therapeutic compounds and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9906933A (pt) * 1998-01-16 2001-11-27 Medivir Ab Antiviróticos
WO1999051613A1 (en) * 1998-04-03 1999-10-14 Medivir Ab Prodrugs of phosphorous-containing pharmaceuticals
SE0100733D0 (sv) 2001-03-05 2001-03-05 Medivir Ab Non-nucleoside reverse transcriptase inhibitors
SE0102867D0 (sv) * 2001-08-28 2001-08-28 Medivir Ab Non-nucleoside reverse transcriptase inhibitors
KR20050033663A (ko) * 2002-09-05 2005-04-12 메디비르 아베 비-뉴클레오시드 역전사효소 억제제

Also Published As

Publication number Publication date
AU2004312284A1 (en) 2005-07-21
US7915295B2 (en) 2011-03-29
BRPI0418306B1 (pt) 2018-09-18
JP2007519640A (ja) 2007-07-19
SG149070A1 (en) 2009-01-29
BRPI0418306A (pt) 2007-05-02
IL176740A0 (en) 2006-10-31
CA2550187A1 (en) 2005-07-21
CA2550187C (en) 2012-08-07
WO2005066131A1 (en) 2005-07-21
EA200601289A1 (ru) 2006-12-29
IL176740A (en) 2011-09-27
EP1701942A1 (en) 2006-09-20
ATE451357T1 (de) 2009-12-15
US20080070951A1 (en) 2008-03-20
ES2337794T3 (es) 2010-04-29
AU2004312284B2 (en) 2010-08-05
BRPI0418306B8 (pt) 2021-05-25
AU2004312284A2 (en) 2005-07-21
HK1101400A1 (en) 2007-10-18
EP1701942B1 (en) 2009-12-09
DE602004024584D1 (de) 2010-01-21
NZ548367A (en) 2010-06-25
EA009700B1 (ru) 2008-02-28
JP4762917B2 (ja) 2011-08-31

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