DK1697752T3 - Assaychip og anvendelser af assaychippen til bestemmelse af molekyl- strukturer og -funktioner - Google Patents

Assaychip og anvendelser af assaychippen til bestemmelse af molekyl- strukturer og -funktioner

Info

Publication number
DK1697752T3
DK1697752T3 DK04820800T DK04820800T DK1697752T3 DK 1697752 T3 DK1697752 T3 DK 1697752T3 DK 04820800 T DK04820800 T DK 04820800T DK 04820800 T DK04820800 T DK 04820800T DK 1697752 T3 DK1697752 T3 DK 1697752T3
Authority
DK
Denmark
Prior art keywords
nanopores
assay chip
layer
support layer
membrane
Prior art date
Application number
DK04820800T
Other languages
English (en)
Inventor
Louis Tiefenauer
Karl Brander
Original Assignee
Scherrer Inst Paul
Leister Process Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherrer Inst Paul, Leister Process Tech filed Critical Scherrer Inst Paul
Application granted granted Critical
Publication of DK1697752T3 publication Critical patent/DK1697752T3/da

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845Methods of identifying protein-protein interactions in protein mixtures

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Nanotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medical Informatics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
DK04820800T 2003-12-23 2004-11-15 Assaychip og anvendelser af assaychippen til bestemmelse af molekyl- strukturer og -funktioner DK1697752T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03029726 2003-12-23
EP04002119A EP1548444A1 (en) 2003-12-23 2004-01-31 An assay chip, and uses of said assay chip to determine molecular structures and functions
PCT/EP2004/012925 WO2005064342A1 (en) 2003-12-23 2004-11-15 An assay chip, and uses of said assay chip to determine molecular structures and functions

Publications (1)

Publication Number Publication Date
DK1697752T3 true DK1697752T3 (da) 2008-08-11

Family

ID=34553646

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04820800T DK1697752T3 (da) 2003-12-23 2004-11-15 Assaychip og anvendelser af assaychippen til bestemmelse af molekyl- strukturer og -funktioner

Country Status (8)

Country Link
US (1) US8105820B2 (da)
EP (2) EP1548444A1 (da)
JP (1) JP4448142B2 (da)
CN (1) CN1902497B (da)
AT (1) ATE391916T1 (da)
DE (1) DE602004013042T2 (da)
DK (1) DK1697752T3 (da)
WO (1) WO2005064342A1 (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2179780T3 (pl) * 2005-05-20 2013-03-29 Aquaporin As Membrana do filtracji wody
KR100840619B1 (ko) 2006-12-19 2008-06-24 한양대학교 산학협력단 표면개질된 리포좀, 이를 포함하는 바이오칩 및 그제조방법
WO2013154750A1 (en) * 2012-04-10 2013-10-17 The Trustees Of Columbia Unversity In The City Of New York Systems and methods for biological ion channel interfaces
CA2756233A1 (en) * 2009-03-26 2010-09-30 Trustees Of Boston University Method for imaging on thin solid-state interface between two fluids
CN102472742B (zh) 2009-07-07 2015-07-22 西门子公司 作为生物芯片的传感器
JP5325735B2 (ja) * 2009-10-05 2013-10-23 エスケー化研株式会社 塗膜形成方法
CN102762746B (zh) 2010-02-23 2015-04-29 克里斯托弗·戈登·阿特伍德 检测生物相关分子及其相互作用性质的方法
EP2474829A1 (en) * 2011-01-07 2012-07-11 Axetris AG Method for determination of molecular structures and functions
CN103380369B (zh) 2011-02-23 2016-12-28 纽约市哥伦比亚大学理事会 使用纳米孔进行单分子检测的系统和方法
WO2012146458A2 (en) 2011-04-26 2012-11-01 Paul Scherrer Institut A method for producing a polymer-based microfluidics system for bioanalytics using biological membranes
GB201202519D0 (en) 2012-02-13 2012-03-28 Oxford Nanopore Tech Ltd Apparatus for supporting an array of layers of amphiphilic molecules and method of forming an array of layers of amphiphilic molecules
KR101569891B1 (ko) * 2012-02-13 2015-11-27 동국대학교 산학협력단 다공성 지지체를 이용한 저분자 포집용 졸-겔 칩 및 이를 이용한 저분자 특이적 물질의 스크리닝 방법
GB201300465D0 (en) 2013-01-11 2013-02-27 Aquaporin As A hollow fiber module having tfc-aquaporin modified membranes
DK177696B1 (en) 2013-02-25 2014-03-17 Aquaporin As Systems for water extraction
CN103592433A (zh) * 2013-11-29 2014-02-19 南京祥中生物科技有限公司 一种生物芯片微阵列布点方法
CN103940864B (zh) * 2014-03-25 2016-03-09 西北大学 双管式单分子微流装置
SG11201700557RA (en) * 2014-07-24 2017-02-27 Toppan Printing Co Ltd Lipid membrane structure, lipid-membrane-structure-immobilization carrier, and method for fusing cells
GB201611770D0 (en) 2016-07-06 2016-08-17 Oxford Nanopore Tech Microfluidic device
WO2018217419A1 (en) * 2017-05-26 2018-11-29 Quantapore, Inc. Stable lipid bilayers on nanopore arrays
JP6911118B2 (ja) * 2017-07-07 2021-07-28 株式会社日立ハイテク 薄膜デバイス保管装置,保管方法及び生体分子計測方法
CN109709185A (zh) * 2017-10-25 2019-05-03 深圳宣泽生物医药有限公司 一种修饰生物探针的纳米孔检测装置及制作方法
EP3938779A1 (en) 2019-03-12 2022-01-19 Oxford Nanopore Technologies Limited Nanopore sensing device and methods of operation and of forming it
CN113574388A (zh) * 2019-05-29 2021-10-29 南京大学 不使用电极的纳米孔单分子分析物检测

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1157743T3 (da) * 1993-10-28 2009-07-06 Houston Advanced Res Ct Mikrofremstillet poröst gennemströmningsapparat til diskret påvisning af bindingsreaktioner
US5716526A (en) * 1994-01-14 1998-02-10 The Liposome Company, Inc. Method of separating materials from liposomes or lipid complexes
AU2206800A (en) * 1998-12-11 2000-06-26 Regents Of The University Of California, The Targeted molecular bar codes and methods for using the same
US6783643B2 (en) * 1999-06-22 2004-08-31 President And Fellows Of Harvard College Control of solid state dimensional features
EP2083015B1 (en) * 2000-02-11 2016-04-06 The Texas A & M University System Biosensor compositions and methods of use
US6716629B2 (en) * 2000-10-10 2004-04-06 Biotrove, Inc. Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof
US6818907B2 (en) * 2000-10-17 2004-11-16 The President And Fellows Of Harvard College Surface plasmon enhanced illumination system
JP2002218974A (ja) * 2001-01-24 2002-08-06 Ebara Corp 反応プローブチップ及び検出システム
WO2003016040A1 (en) * 2001-04-16 2003-02-27 The Regents Of The University Of California Membrane mimetic architectures on nanoporous materials
US6785432B2 (en) * 2001-06-15 2004-08-31 The Regents Of The University Of California Target molecules detection by waveguiding in a photonic silicon membrane
DE10142691B4 (de) * 2001-08-31 2006-04-20 Infineon Technologies Ag Verfahren zum Nachweis biochemischer Reaktionen sowie eine Vorrichtung hierfür
US6875671B2 (en) * 2001-09-12 2005-04-05 Reveo, Inc. Method of fabricating vertical integrated circuits
US20050230272A1 (en) * 2001-10-03 2005-10-20 Lee Gil U Porous biosensing device
US20030104512A1 (en) * 2001-11-30 2003-06-05 Freeman Alex R. Biosensors for single cell and multi cell analysis
US20040120854A1 (en) * 2002-04-04 2004-06-24 Heath James R Silicon-wafer based devices and methods for analyzing biological material
US7744816B2 (en) * 2002-05-01 2010-06-29 Intel Corporation Methods and device for biomolecule characterization

Also Published As

Publication number Publication date
ATE391916T1 (de) 2008-04-15
WO2005064342A1 (en) 2005-07-14
EP1697752B1 (en) 2008-04-09
US8105820B2 (en) 2012-01-31
EP1548444A1 (en) 2005-06-29
DE602004013042T2 (de) 2009-05-14
US20070275480A1 (en) 2007-11-29
CN1902497B (zh) 2012-08-22
EP1697752A1 (en) 2006-09-06
JP2007529003A (ja) 2007-10-18
DE602004013042D1 (de) 2008-05-21
CN1902497A (zh) 2007-01-24
JP4448142B2 (ja) 2010-04-07

Similar Documents

Publication Publication Date Title
DK1697752T3 (da) Assaychip og anvendelser af assaychippen til bestemmelse af molekyl- strukturer og -funktioner
Hovis et al. Patterning and composition arrays of supported lipid bilayers by microcontact printing
McGlennen Miniaturization technologies for molecular diagnostics
Sapsford et al. Kinetics of antigen binding to arrays of antibodies in different sized spots
Kellenberger et al. RNA-based fluorescent biosensors for live cell imaging of second messengers cyclic di-GMP and cyclic AMP-GMP
Sikanen et al. Hybrid ceramic polymers: New, nonbiofouling, and optically transparent materials for microfluidics
SE0403139D0 (sv) Device and use thereof
Shin et al. Multiple conformations of a single SNAREpin between two nanodisc membranes reveal diverse pre-fusion states
Yao et al. High-speed, whole-column fluorescence imaging detection for isoelectric focusing on a microchip using an organic light emitting diode as light source
WO2003068947A8 (en) Assay electrodes having immobilized lipid/protein layers and methods of making and using the same
ATE476494T1 (de) Lichtdurchlässige festmatrix-prüfvorrichtung zur mikroarray-analyse
US20170097332A1 (en) Apparatuses and methods for determining analyte charge
EP2154522A3 (en) Biosensor
SE0100875D0 (sv) Method of preparing supported lipid film membranes and use thereof
DE60212274D1 (de) Elektrochemische vorrichtung unter verwendung von multikomponenten kompositmembranfilm
AR013671A1 (es) Dispositivo de ensayo para la determinacion de substancias a analizar en un producto dietario liquido, procedimiento para la deteccion de substancias a analizar en un producto dietario y kit de ensayo que comprende dicho dispositivo
ATE527543T1 (de) Testvorrichtung zur schnelldiagnose
Kang et al. High-throughput comprehensive peptide mapping of proteins by multiplexed capillary electrophoresis
Larsen et al. How membrane geometry regulates protein sorting independently of mean curvature
Sommer et al. On-chip isoelectric focusing using photopolymerized immobilized pH gradients
Anna et al. Methods for 20S immunoproteasome and 20S constitutive proteasome determination based on SPRI biosensors
Hong et al. Functional GPCR microarrays
Gorodkiewicz et al. Development of an SPR imaging biosensor for determination of cathepsin G in saliva and white blood cells
ATE324583T1 (de) Optischer biosensor
DE60138610D1 (de) Teststreifen mit poröser Filterschicht