DK1696923T3 - Nikotinafgivelsesprodukt og fremgangsmåde til fremstilling deraf - Google Patents

Nikotinafgivelsesprodukt og fremgangsmåde til fremstilling deraf

Info

Publication number
DK1696923T3
DK1696923T3 DK04801165T DK04801165T DK1696923T3 DK 1696923 T3 DK1696923 T3 DK 1696923T3 DK 04801165 T DK04801165 T DK 04801165T DK 04801165 T DK04801165 T DK 04801165T DK 1696923 T3 DK1696923 T3 DK 1696923T3
Authority
DK
Denmark
Prior art keywords
nicotine
delivery product
preparation
exchange resin
cation exchange
Prior art date
Application number
DK04801165T
Other languages
English (en)
Inventor
Carsten Andersen
Original Assignee
Fertin Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fertin Pharma As filed Critical Fertin Pharma As
Application granted granted Critical
Publication of DK1696923T3 publication Critical patent/DK1696923T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10Chemical features of tobacco products or tobacco substitutes
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18Treatment of tobacco products or tobacco substitutes
    • A24B15/28Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/287Treatment of tobacco products or tobacco substitutes by chemical substances by inorganic substances only
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465Nicotine; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A61K47/585Ion exchange resins, e.g. polystyrene sulfonic acid resin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058Chewing gums
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Addiction (AREA)
  • Inorganic Chemistry (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK04801165T 2003-12-02 2004-12-02 Nikotinafgivelsesprodukt og fremgangsmåde til fremstilling deraf DK1696923T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200301782 2003-12-02
US50906303P 2003-12-05 2003-12-05
PCT/DK2004/000841 WO2005053691A2 (en) 2003-12-02 2004-12-02 Nicotine delivery product and method for producing it

Publications (1)

Publication Number Publication Date
DK1696923T3 true DK1696923T3 (da) 2009-12-21

Family

ID=34973436

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04801165T DK1696923T3 (da) 2003-12-02 2004-12-02 Nikotinafgivelsesprodukt og fremgangsmåde til fremstilling deraf

Country Status (6)

Country Link
US (2) US8741935B2 (da)
EP (1) EP1696923B1 (da)
AT (1) ATE439839T1 (da)
DE (1) DE602004022708D1 (da)
DK (1) DK1696923T3 (da)
WO (1) WO2005053691A2 (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2708552T3 (es) 2002-12-20 2019-04-10 Niconovum Ab Método para la preparación de un material particulado que contiene nicotina con una celulosa cristalina (en particular MCC)
DE602006010542D1 (de) * 2005-06-01 2009-12-31 Fertin Pharma As Verfahren zur herstellung eines nikotinzuführenden produkts
AU2007224584A1 (en) 2006-03-16 2007-09-20 Niconovum Ab Improved snuff composition
AU2007224586A1 (en) * 2006-03-16 2007-09-20 Niconovum Ab Stable lozenge compositions providing rapid release of nicotine
ATE533487T1 (de) 2008-12-19 2011-12-15 Siegfried Ltd Nikotinhaltiges produkt
US20110268809A1 (en) 2010-04-28 2011-11-03 Paul Andrew Brinkley Nicotine-Containing Pharmaceutical Compositions
US20110274628A1 (en) 2010-05-07 2011-11-10 Borschke August J Nicotine-containing pharmaceutical compositions
EP2575759B1 (en) 2010-05-31 2016-10-26 Fertin Pharma A/S Formulation comprising nicotine and a cation exchange resin
WO2011150959A1 (en) * 2010-05-31 2011-12-08 Fertin Pharma A/S Formulation comprising nicotine and a cation exchange resin
US9629392B2 (en) 2011-09-22 2017-04-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9474303B2 (en) 2011-09-22 2016-10-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9084439B2 (en) 2011-09-22 2015-07-21 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US20130078307A1 (en) 2011-09-22 2013-03-28 Niconovum Usa, Inc. Nicotine-containing pharmaceutical composition
US9907748B2 (en) 2011-10-21 2018-03-06 Niconovum Usa, Inc. Excipients for nicotine-containing therapeutic compositions
US9763928B2 (en) 2012-02-10 2017-09-19 Niconovum Usa, Inc. Multi-layer nicotine-containing pharmaceutical composition
US20140255452A1 (en) 2013-03-11 2014-09-11 Niconovum Usa, Inc. Method and apparatus for differentiating oral pouch products
ITBO20130706A1 (it) * 2013-12-20 2015-06-21 Sino Business Ltd Composizione per sigarette elettroniche
US20170165252A1 (en) 2015-12-10 2017-06-15 Niconovum Usa Inc. Protein-enriched therapeutic composition
DK3445344T3 (da) 2016-04-21 2020-11-23 Fertin Pharma As Nikotinadministrationsprodukt, relaterede anvendelser og orale doseringsformer, samt fremgangsmåder til fremstilling
US20180103681A1 (en) * 2016-10-18 2018-04-19 Altria Client Services Llc Methods and systems for increasing stability of the pre-vapor formulation of an e-vaping device
BR112020025604A2 (pt) 2018-06-15 2021-03-23 R.J. Reynolds Tobacco Company purificação de nicotina
US20210106516A1 (en) * 2019-10-11 2021-04-15 Fertin Pharma A/S Ion-Exchange Composition With Water-Soluble Mucoadhesive Polymers

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3901248A (en) * 1970-07-22 1975-08-26 Leo Ab Chewable smoking substitute composition
US3845217A (en) * 1972-11-16 1974-10-29 Helsingborg L Ab Buffered smoking substitute compositions
US4692462A (en) 1985-03-18 1987-09-08 Menley & James Laboratories, Ltd. Compositions and method of controlling transdermal penetration of topical and systemic agents
AU5354994A (en) * 1992-10-15 1994-05-09 Alza Corporation Delayed onset transdermal delivery device
GB9310412D0 (en) * 1993-05-20 1993-07-07 Danbiosyst Uk Nasal nicotine system
US6607752B2 (en) 2000-07-27 2003-08-19 Rohm And Haas Company Method for the anhydrous loading of nicotine onto ion exchange resins
CN1615156B (zh) * 2002-01-18 2012-05-30 罗门哈斯公司 制备树脂酸酯的方法
US6586449B1 (en) * 2002-05-28 2003-07-01 Cambrex Charles City, Inc. Nicotine-containing, controlled release composition and method

Also Published As

Publication number Publication date
EP1696923A2 (en) 2006-09-06
DE602004022708D1 (de) 2009-10-01
ATE439839T1 (de) 2009-09-15
US8741935B2 (en) 2014-06-03
US9801408B2 (en) 2017-10-31
US20080038209A1 (en) 2008-02-14
EP1696923B1 (en) 2009-08-19
WO2005053691A2 (en) 2005-06-16
US20140230833A1 (en) 2014-08-21
WO2005053691A3 (en) 2005-07-14

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