UA88481C2 - Донепезила фумарат, пригодный для получения фармацевтических композиций - Google Patents

Донепезила фумарат, пригодный для получения фармацевтических композиций

Info

Publication number
UA88481C2
UA88481C2 UAA200704106A UAA200704106A UA88481C2 UA 88481 C2 UA88481 C2 UA 88481C2 UA A200704106 A UAA200704106 A UA A200704106A UA A200704106 A UAA200704106 A UA A200704106A UA 88481 C2 UA88481 C2 UA 88481C2
Authority
UA
Ukraine
Prior art keywords
preparation
pharmaceutical compositions
donepezil
donepezil fumarate
fumarate
Prior art date
Application number
UAA200704106A
Other languages
English (en)
Ukrainian (uk)
Inventor
Тибор Месей
Дьюла Симиг
Дьюла Лукаш
Марта Порч-Маккай
Балаж Волк
Энико Молнар
Фекете Валерия Хофманне
Original Assignee
Эгиш Дьёдьсердьяр Нирт.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эгиш Дьёдьсердьяр Нирт. filed Critical Эгиш Дьёдьсердьяр Нирт.
Publication of UA88481C2 publication Critical patent/UA88481C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Данное изобретение относится к солям донепезила, пригодных для получения фармацевтических композиций, в частности к фумарату донепезила, представленного формулой ІІ.
UAA200704106A 2004-09-15 2005-09-12 Донепезила фумарат, пригодный для получения фармацевтических композиций UA88481C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU0401850A HUP0401850A3 (en) 2004-09-15 2004-09-15 Donepezil salts for producing pharmaceutical composition

Publications (1)

Publication Number Publication Date
UA88481C2 true UA88481C2 (ru) 2009-10-26

Family

ID=89985497

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200704106A UA88481C2 (ru) 2004-09-15 2005-09-12 Донепезила фумарат, пригодный для получения фармацевтических композиций

Country Status (14)

Country Link
US (1) US20080194628A1 (ru)
EP (1) EP1817286A1 (ru)
CN (1) CN101039910A (ru)
BG (1) BG109855A (ru)
CZ (1) CZ2007248A3 (ru)
EA (1) EA200700637A1 (ru)
HU (1) HUP0401850A3 (ru)
IL (1) IL181827A0 (ru)
NO (1) NO20071912L (ru)
PL (1) PL382842A1 (ru)
RU (1) RU2382032C2 (ru)
SK (1) SK50342007A3 (ru)
UA (1) UA88481C2 (ru)
WO (1) WO2006030249A1 (ru)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004046497A1 (de) * 2004-09-23 2006-04-06 Helm Ag Donepezil-Salze
CA2581926A1 (en) * 2004-09-29 2006-04-06 Chemagis Ltd. Use of purified donepezil maleate for preparing pharmaceutically pure amorphous donepezil hydrochloride
US20090171094A1 (en) * 2005-07-15 2009-07-02 Kazuhide Ashizawa 1-benzyl-4-[(5, 6-dimethoxy- 1- indanon)- 2- yl]-methyl piperidine p-toluenesulfonate or crystal thereof
WO2007108011A2 (en) * 2006-03-20 2007-09-27 Ind-Swift Laboratories Limited Process for the preparation of highly pure donepezil
GB0609835D0 (en) * 2006-05-18 2006-06-28 Pliva Istrazivanje I Razvoj D Impurities of a pharmaceutical product
CN101397270B (zh) * 2007-09-28 2012-03-28 天津和美生物技术有限公司 多奈哌齐盐的多晶型物及其制备和应用
WO2010033045A1 (en) * 2008-09-16 2010-03-25 Igor Anatolievich Pomytkin Compositions and methods for prevention or treatment of beta amyloid deposition
WO2013005094A1 (en) * 2011-07-05 2013-01-10 Torrent Pharmaceuticals Ltd Acid addition salt of donepezil and pharmaceutical composition thereof
EP2586436A1 (en) 2011-10-31 2013-05-01 Commissariat à l'Énergie Atomique et aux Énergies Alternatives Use of anti-connexin agents for enhancing the therapeutic effect of acetylcholinesterase inhibitor
WO2013078608A1 (en) 2011-11-29 2013-06-06 Ziqiang Gu Donepezil pamoate and methods of making and using the same
KR101811797B1 (ko) * 2013-04-03 2017-12-22 동국제약 주식회사 도네페질을 포함하는 비경구투여용 약제학적 조성물
CN109803654B (zh) * 2017-02-23 2022-06-28 上海华汇拓医药科技有限公司 一种多奈哌齐半帕莫酸盐的粉针剂、包含其的组合物及它们的制备方法
CN113164392A (zh) * 2018-11-26 2021-07-23 益霸生物公司 多奈哌齐共熔混合物及其用途
CN120058592A (zh) * 2023-11-28 2025-05-30 广东东阳光药业股份有限公司 多奈哌齐衍生物的盐及其在药物中的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
SK285312B6 (sk) * 1996-06-07 2006-10-05 Eisai Co., Ltd. Polymorf (III) donepezil hydrochloridu, spôsob jeho výroby a terapeutický prostriedok s jeho obsahom
ES2211056T3 (es) * 1999-03-31 2004-07-01 Eisai Co., Ltd. Composiciones estabilizadas que contienen farmacos nootropicos.
DE60034577T2 (de) * 1999-09-01 2007-12-27 Eisai R&D Management Co., Ltd. In 4-stellung substituierte piperidinderivate
JP4150519B2 (ja) * 2000-04-13 2008-09-17 エーザイ・アール・アンド・ディー・マネジメント株式会社 １−ベンジルピリジニウム塩を含有してなるアセチルコリンエステラーゼ阻害剤
US7439365B2 (en) * 2003-11-17 2008-10-21 Usv, Ltd. Pharmaceutical salt of (1-benzyl-4-[(5,6-dimethoxy-1-indanone)-2-yl] methyl piperidine (Donepezil)

Also Published As

Publication number Publication date
HUP0401850A3 (en) 2008-03-28
BG109855A (bg) 2008-04-30
CN101039910A (zh) 2007-09-19
SK50342007A3 (sk) 2007-07-06
RU2007114082A (ru) 2008-10-27
PL382842A1 (pl) 2008-01-21
EP1817286A1 (en) 2007-08-15
WO2006030249A1 (en) 2006-03-23
IL181827A0 (en) 2007-07-04
EA200700637A1 (ru) 2007-08-31
US20080194628A1 (en) 2008-08-14
CZ2007248A3 (cs) 2007-06-20
HU0401850D0 (en) 2004-11-29
RU2382032C2 (ru) 2010-02-20
NO20071912L (no) 2007-06-07
HUP0401850A2 (en) 2006-11-28

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