DK169608B1 - Stabile vandige suspensioner i form af sirupper med retarderet afgivelse indeholdende carbamazepin-dihydratkrystaller, fremgangsmåde til fremstilling deraf samt anvendelse af et beskyttelseskolloid til fremstilling deraf - Google Patents

Stabile vandige suspensioner i form af sirupper med retarderet afgivelse indeholdende carbamazepin-dihydratkrystaller, fremgangsmåde til fremstilling deraf samt anvendelse af et beskyttelseskolloid til fremstilling deraf Download PDF

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Publication number
DK169608B1
DK169608B1 DK238888A DK238888A DK169608B1 DK 169608 B1 DK169608 B1 DK 169608B1 DK 238888 A DK238888 A DK 238888A DK 238888 A DK238888 A DK 238888A DK 169608 B1 DK169608 B1 DK 169608B1
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Prior art keywords
carbamazepine
preparation
protective colloid
cubes
stable aqueous
Prior art date
Application number
DK238888A
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Danish (da)
English (en)
Other versions
DK238888D0 (da
DK238888A (da
Inventor
Satish Chandra Khanna
Original Assignee
Ciba Geigy Ag
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Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK238888D0 publication Critical patent/DK238888D0/da
Publication of DK238888A publication Critical patent/DK238888A/da
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK238888A 1987-05-04 1988-05-03 Stabile vandige suspensioner i form af sirupper med retarderet afgivelse indeholdende carbamazepin-dihydratkrystaller, fremgangsmåde til fremstilling deraf samt anvendelse af et beskyttelseskolloid til fremstilling deraf DK169608B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH168287 1987-05-04
CH168287 1987-05-04

Publications (3)

Publication Number Publication Date
DK238888D0 DK238888D0 (da) 1988-05-03
DK238888A DK238888A (da) 1988-11-05
DK169608B1 true DK169608B1 (da) 1994-12-27

Family

ID=4216129

Family Applications (1)

Application Number Title Priority Date Filing Date
DK238888A DK169608B1 (da) 1987-05-04 1988-05-03 Stabile vandige suspensioner i form af sirupper med retarderet afgivelse indeholdende carbamazepin-dihydratkrystaller, fremgangsmåde til fremstilling deraf samt anvendelse af et beskyttelseskolloid til fremstilling deraf

Country Status (21)

Country Link
US (1) US5122543A (no)
EP (1) EP0289977B1 (no)
JP (1) JPH01131117A (no)
KR (1) KR960006059B1 (no)
AT (1) ATE94390T1 (no)
AU (1) AU619178B2 (no)
CA (1) CA1328219C (no)
DD (1) DD269784A5 (no)
DE (1) DE3884044D1 (no)
DK (1) DK169608B1 (no)
ES (1) ES2043716T3 (no)
FI (1) FI882044A (no)
HU (1) HU199074B (no)
IE (1) IE63081B1 (no)
IL (1) IL86211A (no)
MX (1) MX11339A (no)
NO (1) NO881933L (no)
NZ (1) NZ224476A (no)
PH (1) PH24895A (no)
PT (1) PT87381B (no)
ZA (1) ZA883135B (no)

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US5656286A (en) 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5676968A (en) * 1991-10-31 1997-10-14 Schering Aktiengesellschaft Transdermal therapeutic systems with crystallization inhibitors
DE4210711A1 (de) * 1991-10-31 1993-05-06 Schering Ag Berlin Und Bergkamen, 1000 Berlin, De Transdermale therapeutische systeme mit kristallisationsinhibitoren
DE4422881A1 (de) * 1993-10-25 1995-04-27 Bayer Ag Kolloidal dispergierbare Wirkstoff-Formulierungen
CA2185803C (en) * 1994-03-18 2006-07-11 Edward M. Rudnic Emulsified drug delivery systems
DE4423078B4 (de) * 1994-07-01 2005-01-13 Awd.Pharma Gmbh & Co. Kg Verfahren zur Herstellung einer Carbamazepin-Arzneiform mit verzögerter Wirkstofffreisetzung
DE69825322T2 (de) * 1997-12-19 2005-07-14 Taro Pharmaceuticals U.S.A., Inc. Topische carbamazepin-formulierungen und deren verwendung
GB9930058D0 (en) * 1999-12-20 2000-02-09 Novartis Ag Organic compounds
US8067032B2 (en) * 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
US6977085B2 (en) * 2000-12-22 2005-12-20 Baxter International Inc. Method for preparing submicron suspensions with polymorph control
US6884436B2 (en) * 2000-12-22 2005-04-26 Baxter International Inc. Method for preparing submicron particle suspensions
US20050048126A1 (en) * 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
US6951656B2 (en) * 2000-12-22 2005-10-04 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
US20040256749A1 (en) * 2000-12-22 2004-12-23 Mahesh Chaubal Process for production of essentially solvent-free small particles
US9700866B2 (en) * 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
US7193084B2 (en) * 2000-12-22 2007-03-20 Baxter International Inc. Polymorphic form of itraconazole
US6869617B2 (en) * 2000-12-22 2005-03-22 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
US20030072807A1 (en) * 2000-12-22 2003-04-17 Wong Joseph Chung-Tak Solid particulate antifungal compositions for pharmaceutical use
US20040022862A1 (en) * 2000-12-22 2004-02-05 Kipp James E. Method for preparing small particles
ATE319432T1 (de) * 2000-12-22 2006-03-15 Baxter Int Verfahren zur herstellung von submikropartikel- suspensionen pharmazeutischer substanzen
IN190699B (no) 2001-02-02 2003-08-16 Sun Pharmaceutical Ind Ltd
JP2005504090A (ja) * 2001-09-26 2005-02-10 バクスター・インターナショナル・インコーポレイテッド 分散体および溶媒相または液相の除去によるサブミクロンサイズ−ナノ粒子の調製
US20060003012A9 (en) * 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
US7112340B2 (en) 2001-10-19 2006-09-26 Baxter International Inc. Compositions of and method for preparing stable particles in a frozen aqueous matrix
AU2003231919A1 (en) * 2002-03-14 2003-09-22 Sun Pharmaceutical Industries Limited Oral controlled drug delivery system containing carbamazepine
US20060280787A1 (en) * 2005-06-14 2006-12-14 Baxter International Inc. Pharmaceutical formulation of the tubulin inhibitor indibulin for oral administration with improved pharmacokinetic properties, and process for the manufacture thereof
AU2006259594A1 (en) * 2005-06-14 2006-12-28 Baxter Healthcare S.A. Pharmaceutical formulations for minimizing drug-drug interactions
US20070134341A1 (en) * 2005-11-15 2007-06-14 Kipp James E Compositions of lipoxygenase inhibitors
US20090152176A1 (en) * 2006-12-23 2009-06-18 Baxter International Inc. Magnetic separation of fine particles from compositions
US8722736B2 (en) * 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol
US8426467B2 (en) * 2007-05-22 2013-04-23 Baxter International Inc. Colored esmolol concentrate
US20080293814A1 (en) * 2007-05-22 2008-11-27 Deepak Tiwari Concentrate esmolol
US9394327B1 (en) * 2013-03-15 2016-07-19 The Trustees Of California State University Nucleoside crystals, crystal nucleation and growth control with antifreeze proteins
JP2017537881A (ja) * 2014-11-18 2017-12-21 ピクサーバイオ コーポレーション 急性、術後、または慢性疼痛を治療する組成物およびその使用方法

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US2861920A (en) * 1954-05-04 1958-11-25 Upjohn Co Therapeutic suspensions of steroids containing pvp and/or pva
US4213963A (en) * 1978-12-14 1980-07-22 Janssen Pharmaceutica N.V. Fluspirilene-containing compositions
US4431641A (en) * 1980-10-17 1984-02-14 Ciba-Geigy Corporation Pharmaceutical compositions having antiepileptic and antineuralgic action
CH649080A5 (de) * 1981-04-16 1985-04-30 Ciba Geigy Ag 5h-dibenz(b,f)azepin-5-carboxamide als mittel zur prophylaxe und behandlung von zerebraler leistungsinsuffizienz.
JPS59147374A (ja) * 1983-02-10 1984-08-23 Fuji Xerox Co Ltd 電子写真複写機のブラシクリ−ニング方法
DE3306250A1 (de) * 1983-02-23 1984-08-23 Basf Ag, 6700 Ludwigshafen Sphaerische einkristalle fuer pharmazeutische zwecke
US4548990A (en) * 1983-08-15 1985-10-22 Ciba-Geigy Corporation Crosslinked, porous polymers for controlled drug delivery
EP0200213B1 (en) * 1985-05-02 1992-07-22 Ciba-Geigy Ag Hydrogels with increased organic solvent soluble active agent loading capacity, their preparation and the use thereof
CH668187A5 (de) * 1986-08-07 1988-12-15 Ciba Geigy Ag Therapeutisches system mit systemischer wirkung.
JPH0641286B2 (ja) * 1987-05-14 1994-06-01 信行 西井 自動包装装置
US4964606A (en) * 1989-10-26 1990-10-23 Ncr Corporation Overhead mount for a CRT

Also Published As

Publication number Publication date
KR960006059B1 (ko) 1996-05-08
AU619178B2 (en) 1992-01-23
PT87381B (pt) 1992-08-31
CA1328219C (en) 1994-04-05
AU1555888A (en) 1988-11-10
ZA883135B (en) 1988-11-07
HUT46847A (en) 1988-12-28
IE63081B1 (en) 1995-03-22
KR880013550A (ko) 1988-12-21
FI882044A (fi) 1988-11-05
FI882044A0 (fi) 1988-05-02
NO881933L (no) 1988-11-07
ATE94390T1 (de) 1993-10-15
DE3884044D1 (de) 1993-10-21
IL86211A0 (en) 1988-11-15
IL86211A (en) 1992-03-29
EP0289977B1 (de) 1993-09-15
IE881328L (en) 1988-11-04
HU199074B (en) 1990-01-29
EP0289977A1 (de) 1988-11-09
DK238888D0 (da) 1988-05-03
PH24895A (en) 1990-12-26
MX11339A (es) 1993-12-01
US5122543A (en) 1992-06-16
PT87381A (pt) 1989-05-31
NZ224476A (en) 1990-09-26
JPH01131117A (ja) 1989-05-24
DD269784A5 (de) 1989-07-12
NO881933D0 (no) 1988-05-03
ES2043716T3 (es) 1994-01-01
DK238888A (da) 1988-11-05

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment
B1 Patent granted (law 1993)
PBP Patent lapsed