DK169586B1 - Histil ukendt rottemyelomacellelinie, hybridcellelinie afledt deraf, in vitro cellekultursystem og cellefusionssystem omfattende celler herfra, fremgangsmåde til fremstilling af en hybridcellelinie samt fremgangsmåde til fremstilling af monoklonale antistoffer - Google Patents
Histil ukendt rottemyelomacellelinie, hybridcellelinie afledt deraf, in vitro cellekultursystem og cellefusionssystem omfattende celler herfra, fremgangsmåde til fremstilling af en hybridcellelinie samt fremgangsmåde til fremstilling af monoklonale antistoffer Download PDFInfo
- Publication number
- DK169586B1 DK169586B1 DK007380A DK7380A DK169586B1 DK 169586 B1 DK169586 B1 DK 169586B1 DK 007380 A DK007380 A DK 007380A DK 7380 A DK7380 A DK 7380A DK 169586 B1 DK169586 B1 DK 169586B1
- Authority
- DK
- Denmark
- Prior art keywords
- cells
- cell line
- rat
- hybrid
- immunogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/91—Cell lines ; Processes using cell lines
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Semiconductor Memories (AREA)
- Static Random-Access Memory (AREA)
- Internal Circuitry In Semiconductor Integrated Circuit Devices (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7900775 | 1979-01-09 | ||
GB7900775 | 1979-01-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
DK7380A DK7380A (da) | 1980-07-10 |
DK169586B1 true DK169586B1 (da) | 1994-12-12 |
Family
ID=10502406
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK007380A DK169586B1 (da) | 1979-01-09 | 1980-01-07 | Histil ukendt rottemyelomacellelinie, hybridcellelinie afledt deraf, in vitro cellekultursystem og cellefusionssystem omfattende celler herfra, fremgangsmåde til fremstilling af en hybridcellelinie samt fremgangsmåde til fremstilling af monoklonale antistoffer |
Country Status (11)
Country | Link |
---|---|
US (1) | US4350683A (fr) |
EP (1) | EP0014519B1 (fr) |
JP (3) | JPS55113722A (fr) |
AT (1) | ATE2965T1 (fr) |
AU (1) | AU542303B2 (fr) |
CA (1) | CA1142466A (fr) |
DE (1) | DE3062558D1 (fr) |
DK (1) | DK169586B1 (fr) |
GB (1) | GB2039948B (fr) |
IE (1) | IE50418B1 (fr) |
ZA (1) | ZA797020B (fr) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0043718B1 (fr) * | 1980-07-07 | 1984-11-28 | National Research Development Corporation | Lignées de cellules |
EP0044219A1 (fr) * | 1980-07-16 | 1982-01-20 | Unilever Plc | Méthodes d'analyse immunologique utilisant des anticorps monoclonaux |
IL62965A0 (en) * | 1980-07-17 | 1981-07-31 | Scripps Miles Lab Inc | Monoclonal antibodies to drugs and theri production |
US4608337A (en) * | 1980-11-07 | 1986-08-26 | The Wistar Institute | Human hybridomas and the production of human monoclonal antibodies by human hybridomas |
US4722896A (en) * | 1981-01-26 | 1988-02-02 | The Beth Israel Hospital Association | Method for affinity purification of hybridoma antibodies |
DE3235924T1 (de) * | 1981-03-06 | 1983-05-05 | Celltech Ltd., Slough, Berkshire | Monoklonaler antikoerper |
US4474893A (en) * | 1981-07-01 | 1984-10-02 | The University of Texas System Cancer Center | Recombinant monoclonal antibodies |
US4714681A (en) * | 1981-07-01 | 1987-12-22 | The Board Of Reagents, The University Of Texas System Cancer Center | Quadroma cells and trioma cells and methods for the production of same |
US4987079A (en) * | 1982-07-06 | 1991-01-22 | Wilbur D. Smith | Composition and method for in vitro cell culture |
US4517289A (en) * | 1982-08-18 | 1985-05-14 | Brigham And Women's Hospital | Monoclonal antibodies for human tissue cross-matching |
US4950598A (en) * | 1982-09-22 | 1990-08-21 | The Board Of Trustees Of The Leland Stanford Junior University | Process for making T cell hybridomas |
EP0139676B1 (fr) * | 1983-02-04 | 1992-11-25 | Cytoclonal Pharmaceutics Inc. | Production et caracterisation d'anticorps d'hybridomes diriges specifiquement contre un/des determinant(s) commun(s) present(s) parmi des proteines en relation etroite mais distinctes |
US4508643A (en) * | 1983-02-08 | 1985-04-02 | Baxter Travenol Laboratories, Inc. | Rat antibody to hCG |
GB8318575D0 (en) * | 1983-07-08 | 1983-08-10 | Cobbold S P | Antibody preparations |
US4468346A (en) * | 1983-10-27 | 1984-08-28 | The United States Of America As Represented By The Secretary Of Agriculture | Monoclonal antibodies to porcine immunoglobulins |
US4469630A (en) * | 1983-11-25 | 1984-09-04 | J. T. Baker Chemical Co. | Purification of monoclonal antibodies |
US4596769A (en) * | 1984-03-05 | 1986-06-24 | Temple University | Monoclonal antibodies to peptidoglycan and methods of preparing same |
US4604235A (en) * | 1984-05-23 | 1986-08-05 | J. T. Baker Chemical Company | Purification of monoclonal antibodies |
JPS60258128A (ja) * | 1984-06-06 | 1985-12-20 | Kyowa Hakko Kogyo Co Ltd | ラツトモノクロ−ナル抗体 |
US4791068A (en) * | 1984-06-22 | 1988-12-13 | Scripps Clinic And Research Foundation | Diagnostic assay for inhibitor of tissue-type and urokinase-type plasminogen activators |
JPS6179164A (ja) * | 1984-09-26 | 1986-04-22 | Amano Pharmaceut Co Ltd | 抗原抗体反応の短縮方法 |
US4757018A (en) * | 1985-02-11 | 1988-07-12 | Hazleton Biotechnologies, Inc. | Myeloma cell lines and uses thereof |
US4814275A (en) * | 1985-05-13 | 1989-03-21 | E.I. Dupont De Nemours And Company | Monoclonal hybridoma antibody specific for a human epithelial antigen |
CA1302919C (fr) * | 1985-07-03 | 1992-06-09 | Robert T. Buckler | Derives de l'histamine, conjugues immunogenes et antibiotiques obtenus a partir de ceux-ci |
US5292636A (en) * | 1986-03-31 | 1994-03-08 | T Cell Diagnostics, Inc. | Therapeutic and diagnostic methods using soluble T cell surface molecules |
EP0318487B1 (fr) * | 1986-08-04 | 1993-10-13 | The University Of New South Wales | Milieu de culture de tissus sans serum contenant un agent protecteur de cellules polymere |
US5939391A (en) * | 1993-03-31 | 1999-08-17 | Pro-Neuron, Inc. | Hemoglobin alpha chain peptide fragments useful for inhibiting stem cell proliferation |
CN1089344C (zh) * | 1993-03-31 | 2002-08-21 | 普罗神经细胞有限公司 | 干细胞增生的抑制剂及其应用 |
US6610654B2 (en) * | 1993-03-31 | 2003-08-26 | Wellstat Therapeutics Corporation | Inhibitor of stem cell proliferation and uses thereof |
US5861483A (en) | 1996-04-03 | 1999-01-19 | Pro-Neuron, Inc. | Inhibitor of stem cell proliferation and uses thereof |
ES2568899T3 (es) * | 1999-04-09 | 2016-05-05 | Kyowa Hakko Kirin Co., Ltd. | Procedimiento para controlar la actividad de una molécula inmunofuncional |
JP4668498B2 (ja) * | 1999-10-19 | 2011-04-13 | 協和発酵キリン株式会社 | ポリペプチドの製造方法 |
US6946292B2 (en) * | 2000-10-06 | 2005-09-20 | Kyowa Hakko Kogyo Co., Ltd. | Cells producing antibody compositions with increased antibody dependent cytotoxic activity |
JPWO2003084569A1 (ja) | 2002-04-09 | 2005-08-11 | 協和醗酵工業株式会社 | 抗体組成物含有医薬 |
US7340957B2 (en) | 2004-07-29 | 2008-03-11 | Los Alamos National Security, Llc | Ultrasonic analyte concentration and application in flow cytometry |
CA2580076A1 (fr) * | 2004-09-10 | 2006-03-23 | Cornell Research Foundation, Inc | Derives de betulinol utilises en tant qu'agents anti-vih |
CA2597673C (fr) | 2005-02-11 | 2014-07-08 | Harold Varmus | Methodes et compositions pour detecter un mutant d'egfr resistant aux medicaments |
US7835000B2 (en) | 2006-11-03 | 2010-11-16 | Los Alamos National Security, Llc | System and method for measuring particles in a sample stream of a flow cytometer or the like |
WO2008122051A1 (fr) * | 2007-04-02 | 2008-10-09 | Acoustic Cytometry Systems, Inc. | Procédés et dispositifs pour l'analyse amplifiée de cellules et particules focalisées sur champ |
US8083068B2 (en) | 2007-04-09 | 2011-12-27 | Los Alamos National Security, Llc | Apparatus for separating particles utilizing engineered acoustic contrast capture particles |
US7837040B2 (en) * | 2007-04-09 | 2010-11-23 | Los Alamos National Security, Llc | Acoustic concentration of particles in fluid flow |
US8263407B2 (en) | 2007-10-24 | 2012-09-11 | Los Alamos National Security, Llc | Method for non-contact particle manipulation and control of particle spacing along an axis |
US8528406B2 (en) | 2007-10-24 | 2013-09-10 | Los Alamos National Security, LLP | Method for non-contact particle manipulation and control of particle spacing along an axis |
US8266951B2 (en) | 2007-12-19 | 2012-09-18 | Los Alamos National Security, Llc | Particle analysis in an acoustic cytometer |
US8714014B2 (en) | 2008-01-16 | 2014-05-06 | Life Technologies Corporation | System and method for acoustic focusing hardware and implementations |
KR102168357B1 (ko) | 2016-03-28 | 2020-10-22 | 도요세이칸 그룹 홀딩스 가부시키가이샤 | 분산액과 그의 제조 방법, 및 구리 화합물 입자 |
JP6984122B2 (ja) * | 2016-12-15 | 2021-12-17 | 東洋製罐グループホールディングス株式会社 | 抗ウイルス性を有する分散液 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI64952C (fi) * | 1977-06-15 | 1984-02-10 | Wistar Inst | Foerfarande foer framstaellning av genetiskt stabila cellinjer |
US4196265A (en) * | 1977-06-15 | 1980-04-01 | The Wistar Institute | Method of producing antibodies |
US4172124A (en) * | 1978-04-28 | 1979-10-23 | The Wistar Institute | Method of producing tumor antibodies |
-
1979
- 1979-12-21 CA CA000342515A patent/CA1142466A/fr not_active Expired
- 1979-12-27 ZA ZA00797020A patent/ZA797020B/xx unknown
-
1980
- 1980-01-03 US US06/109,391 patent/US4350683A/en not_active Expired - Lifetime
- 1980-01-07 DK DK007380A patent/DK169586B1/da active
- 1980-01-08 IE IE32/80A patent/IE50418B1/en not_active IP Right Cessation
- 1980-01-08 EP EP80300077A patent/EP0014519B1/fr not_active Expired
- 1980-01-08 AU AU54456/80A patent/AU542303B2/en not_active Expired
- 1980-01-08 AT AT80300077T patent/ATE2965T1/de not_active IP Right Cessation
- 1980-01-08 GB GB8000595A patent/GB2039948B/en not_active Expired
- 1980-01-08 DE DE8080300077T patent/DE3062558D1/de not_active Expired
- 1980-01-09 JP JP123380A patent/JPS55113722A/ja active Granted
-
1990
- 1990-01-25 JP JP2015947A patent/JPH02227096A/ja active Granted
-
1992
- 1992-07-09 JP JP4182190A patent/JP2648419B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
IE800032L (en) | 1980-07-09 |
JPH02227096A (ja) | 1990-09-10 |
JPH05276983A (ja) | 1993-10-26 |
JPH032515B2 (fr) | 1991-01-16 |
AU542303B2 (en) | 1985-02-14 |
CA1142466A (fr) | 1983-03-08 |
ATE2965T1 (de) | 1983-04-15 |
ZA797020B (en) | 1981-08-26 |
US4350683A (en) | 1982-09-21 |
JPS55113722A (en) | 1980-09-02 |
AU5445680A (en) | 1980-07-17 |
EP0014519B1 (fr) | 1983-04-06 |
GB2039948A (en) | 1980-08-20 |
IE50418B1 (en) | 1986-04-16 |
EP0014519A3 (en) | 1981-01-07 |
GB2039948B (en) | 1983-04-07 |
EP0014519A2 (fr) | 1980-08-20 |
JP2648419B2 (ja) | 1997-08-27 |
DE3062558D1 (en) | 1983-05-11 |
JPH052318B2 (fr) | 1993-01-12 |
DK7380A (da) | 1980-07-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK169586B1 (da) | Histil ukendt rottemyelomacellelinie, hybridcellelinie afledt deraf, in vitro cellekultursystem og cellefusionssystem omfattende celler herfra, fremgangsmåde til fremstilling af en hybridcellelinie samt fremgangsmåde til fremstilling af monoklonale antistoffer | |
US4472500A (en) | Rat myeloma cell lines | |
US4468346A (en) | Monoclonal antibodies to porcine immunoglobulins | |
US5643736A (en) | Monoclonal antibodies for human osteogenic cell surface antigens | |
DK154086B (da) | Monoklonalt antistof, fremstilling deraf, hybridomacellelinie til anvendelse ved fremstilling heraf samt fremgangsmaade til diagnose ved anvendelse heraf | |
US4517289A (en) | Monoclonal antibodies for human tissue cross-matching | |
EP0102601A2 (fr) | Anticorps monoclonal, procédé pour sa production et application de cet anticorps monoclonal | |
EP0057107A2 (fr) | Procédé de préparation d'anticorps monoclonaux et cellules aptes à produire ces anticorps | |
US5024946A (en) | Human monoclonal antibody to antigen of gastric cancer and B-cell line for producing this antibody, method for preparing this B-cell line and antibody, antigen and method of preparation of this antigen | |
CA1213227A (fr) | Lignee de cellules plasmocytoides humaines non secretrices | |
CA1330768C (fr) | Anticorps monoclonal anti-facteur de stimulation des colonies de granulocytes humain | |
Letchworth | Methods for production of monoclonal antibodies | |
EP0077571A2 (fr) | Procédé de production d'une lymphokine | |
GB2079313A (en) | Improvements in or relating to rat myeloma cell lines | |
JP3043023B2 (ja) | ハイブリドーマ | |
KR900007950B1 (ko) | 모노클로날 항체의 제조방법 | |
SU1595902A1 (ru) | Штамм гибридных культивируемых клеток животных MUS мUSсULUS L, используемый дл получени моноклональных антител к антигену СД38 кортикальных тимоцитов | |
RU1801117C (ru) | Способ получения монокло- нального антитела к моноклональному антителу к белку т4 лимфоцита человека, культивируемая клетка гибридомы jthfs-про- дуцентмоноклонального антитела к моноклональному антителу к белку т4 лимфоцита чело- века, культивируемая клетка гибридомы jti-if3-f5 - продуцент моноклонального антитела к моноклональному антителу к белку т4 лимфоцитачеловека, культивируемая клетка гибридомы jti-id7 - про- дуцент моноклонального антитела к моноклональному антителу к белку т4 лимфоцита человека, культивируемая клетка гибридомы jt2-n15 - продуцент моноклонального антитела к моноклональному антителу к белку т4 лимфоцитачеловека | |
USRE33252E (en) | Hybridoma antibody which inhibits Interleukin 2 activity | |
Litwin et al. | Change in Ig Expression of a Human Lymphoblastoid Line During Long‐Term Culture | |
JP3753392B2 (ja) | ニワトリチミジンキナーゼ欠損ウアバイン耐性ハイブリドーマ | |
RU1776691C (ru) | Штамм гибридных культивируемых клеток животных MUS мUSсULUS L, - продуцент моноклональных антител против J @ Е человека | |
US5849539A (en) | Thymidine kinase-lacking ouabain-resistant chicken hybridoma | |
JPH01257477A (ja) | 安定なウサギ−マウスハイブリドーマ及びその分泌物 | |
WO1986002366A1 (fr) | Hybridomes de l'interespece aotus et recepteurs monoclonaux relatifs |