DK1694660T3 - Fremgangsmåde til fremstilling af vandfri og hydrerede aktive farmaceutiske bestanddele (API's); stabile farmaceutiske sammensætninger fremstillet af disse og anvendelser af disse sammensætninger - Google Patents

Fremgangsmåde til fremstilling af vandfri og hydrerede aktive farmaceutiske bestanddele (API's); stabile farmaceutiske sammensætninger fremstillet af disse og anvendelser af disse sammensætninger

Info

Publication number
DK1694660T3
DK1694660T3 DK04801143T DK04801143T DK1694660T3 DK 1694660 T3 DK1694660 T3 DK 1694660T3 DK 04801143 T DK04801143 T DK 04801143T DK 04801143 T DK04801143 T DK 04801143T DK 1694660 T3 DK1694660 T3 DK 1694660T3
Authority
DK
Denmark
Prior art keywords
beta
apis
preparation
compositions
anhydrous
Prior art date
Application number
DK04801143T
Other languages
English (en)
Inventor
Marco Antonio Santini
Aurelio Maranduba
Eneida Guimaraes
Junior Marcio Santiago
Richard Grazul
Antonio Salustiano Machado
Silva Maria Mirtes Da
Original Assignee
Biorganica Ltda
Quiral Quimica Do Brasil
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from BRPI0405797 external-priority patent/BRPI0405797B1/pt
Application filed by Biorganica Ltda, Quiral Quimica Do Brasil filed Critical Biorganica Ltda
Application granted granted Critical
Publication of DK1694660T3 publication Critical patent/DK1694660T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
DK04801143T 2003-12-12 2004-12-10 Fremgangsmåde til fremstilling af vandfri og hydrerede aktive farmaceutiske bestanddele (API's); stabile farmaceutiske sammensætninger fremstillet af disse og anvendelser af disse sammensætninger DK1694660T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
BR0305824 2003-12-12
BRPI0405797 BRPI0405797B1 (pt) 2004-12-08 2004-12-08 processo para a preparação de princìpios farmacêuticos ativos (pfa's), anidros e hidratados; composições farmacêuticas estáveis a partir dos mesmos e usos das composições
PCT/BR2004/000242 WO2005061474A1 (en) 2003-12-12 2004-12-10 Process for the preparation of anhydrous and hydrated active pharmaceutical ingredients (apis); stable pharmaceutical compositions prepared from the same and uses of said compositions

Publications (1)

Publication Number Publication Date
DK1694660T3 true DK1694660T3 (da) 2009-08-10

Family

ID=37719821

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04801143T DK1694660T3 (da) 2003-12-12 2004-12-10 Fremgangsmåde til fremstilling af vandfri og hydrerede aktive farmaceutiske bestanddele (API's); stabile farmaceutiske sammensætninger fremstillet af disse og anvendelser af disse sammensætninger

Country Status (8)

Country Link
US (2) US7838551B2 (da)
EP (2) EP1947094A3 (da)
AT (1) ATE427943T1 (da)
DE (1) DE602004020506D1 (da)
DK (1) DK1694660T3 (da)
ES (1) ES2325506T3 (da)
PT (1) PT1694660E (da)
WO (1) WO2005061474A1 (da)

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ES2325506T3 (es) 2003-12-12 2009-09-07 Quiral Quimica Do Brasil Procedimiento para la preparacion de principios activos farmaceuticos (api) anhidros e hidratados; composiciones farmaceuticas estables preparadas a partir de los mismos y usos de dichas composiciones.
NZ592132A (en) * 2005-08-31 2012-12-21 Abraxis Bioscience Llc Composition comprising nanoparticles of docitaxel and a citrate
EP1931321B1 (en) 2005-08-31 2018-12-26 Abraxis BioScience, LLC Compositions comprising poorly water soluble pharmaceutical agents and antimicrobial agents
KR100995390B1 (ko) * 2006-01-02 2010-11-19 주식회사 삼양제넥스 무정형, 무수결정형 또는 수화 결정형 도세탁셀의 제조방법
BRPI0600194A (pt) * 2006-01-30 2007-10-23 Quiral Quimica Do Brasil S A composições farmacêuticas contendo docetaxel e um inibidor de degradação e processo de obtenção das mesmas
WO2007124700A2 (en) 2006-05-03 2007-11-08 I.Q.A., A.S. Pharmaceutical composition containing taxane derivative destined for the preparation of an infusion solution, method of preparation thereof and use thereof
AU2007309534B2 (en) * 2006-10-20 2012-08-16 Scinopharm Singapore Pte, Ltd. Process for making crystalline anhydrous docetaxel
WO2008102374A1 (en) * 2007-02-20 2008-08-28 Dabur Pharma Limited Amorphous form of docetaxel
KR100878455B1 (ko) * 2007-04-10 2009-01-13 한미약품 주식회사 안정한 무수결정형 도세탁셀 및 이의 제조방법
EP2080763A1 (en) * 2008-01-18 2009-07-22 INDENA S.p.A. Crystalline form I of ortataxel
DK2080764T3 (da) 2008-01-18 2012-09-24 Indena Spa Faste former af ortataxel
KR100965867B1 (ko) * 2009-06-23 2010-06-24 주식회사 삼양제넥스 수화결정형 도세탁셀의 제조방법
KR101149600B1 (ko) * 2009-12-31 2012-05-29 주식회사 삼양제넥스바이오 고순도 무수결정형 도세탁셀 제조방법
KR101752944B1 (ko) 2010-05-03 2017-07-03 테이코쿠 팔마 유에스에이, 인코포레이티드 비수성의 탁산 프로에멀젼 제제, 및 그의 제조 및 사용 방법
CN102250047B (zh) * 2011-08-26 2013-06-05 贺金凤 一种紫杉醇化合物的制备方法
WO2013096596A1 (en) * 2011-12-20 2013-06-27 Latham Keith R Sustained drug release and improved product stability using non-covalent particle coating methods
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
US10004824B2 (en) * 2015-05-11 2018-06-26 Laboratoires Vivacy Compositions comprising at least one polyol and at least one anesthetic
CN111718316A (zh) * 2020-07-02 2020-09-29 无锡紫杉药业有限公司 一种三水多西他赛生产工艺

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JP2004536026A (ja) * 2000-11-28 2004-12-02 トランスフォーム ファーマシューティカルズ，インコーポレーティッド． パクリタキセル、その誘導体、および薬剤として許容される塩を含む医薬品製剤
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Also Published As

Publication number Publication date
DE602004020506D1 (de) 2009-05-20
WO2005061474A1 (en) 2005-07-07
US7838551B2 (en) 2010-11-23
ES2325506T3 (es) 2009-09-07
US20080051450A1 (en) 2008-02-28
EP1694660B1 (en) 2009-04-08
EP1694660A1 (en) 2006-08-30
EP1947094A3 (en) 2009-02-18
US20090069409A1 (en) 2009-03-12
EP1947094A2 (en) 2008-07-23
PT1694660E (pt) 2009-07-16
ATE427943T1 (de) 2009-04-15
US8304450B2 (en) 2012-11-06

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