DK169346B1 - Tetradecapeptider (thrombin-beta-kæde-homologe) med mitogen aktivitet og fysiologisk acceptable salte deraf samt fremgangsmåde til stimulering af væksten af makrofag-lignende celler - Google Patents

Tetradecapeptider (thrombin-beta-kæde-homologe) med mitogen aktivitet og fysiologisk acceptable salte deraf samt fremgangsmåde til stimulering af væksten af makrofag-lignende celler Download PDF

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Publication number
DK169346B1
DK169346B1 DK489086A DK489086A DK169346B1 DK 169346 B1 DK169346 B1 DK 169346B1 DK 489086 A DK489086 A DK 489086A DK 489086 A DK489086 A DK 489086A DK 169346 B1 DK169346 B1 DK 169346B1
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DK
Denmark
Prior art keywords
cells
peptide
thrombin
asn
macrophage
Prior art date
Application number
DK489086A
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Danish (da)
English (en)
Other versions
DK489086D0 (da
DK489086A (da
Inventor
George Dubar Wilner
Original Assignee
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Publication of DK489086D0 publication Critical patent/DK489086D0/da
Publication of DK489086A publication Critical patent/DK489086A/da
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Publication of DK169346B1 publication Critical patent/DK169346B1/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6429—Thrombin (3.4.21.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21005—Thrombin (3.4.21.5)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK489086A 1985-10-15 1986-10-14 Tetradecapeptider (thrombin-beta-kæde-homologe) med mitogen aktivitet og fysiologisk acceptable salte deraf samt fremgangsmåde til stimulering af væksten af makrofag-lignende celler DK169346B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/787,411 US4704451A (en) 1985-10-15 1985-10-15 Mitogenic peptides
US78741185 1985-10-15

Publications (3)

Publication Number Publication Date
DK489086D0 DK489086D0 (da) 1986-10-14
DK489086A DK489086A (da) 1987-04-16
DK169346B1 true DK169346B1 (da) 1994-10-10

Family

ID=25141385

Family Applications (1)

Application Number Title Priority Date Filing Date
DK489086A DK169346B1 (da) 1985-10-15 1986-10-14 Tetradecapeptider (thrombin-beta-kæde-homologe) med mitogen aktivitet og fysiologisk acceptable salte deraf samt fremgangsmåde til stimulering af væksten af makrofag-lignende celler

Country Status (13)

Country Link
US (1) US4704451A (no)
EP (1) EP0220157B1 (no)
JP (1) JPH0689031B2 (no)
AT (1) ATE69240T1 (no)
AU (1) AU595249B2 (no)
CA (1) CA1299814C (no)
DE (1) DE3682368D1 (no)
DK (1) DK169346B1 (no)
FI (1) FI85379C (no)
IE (1) IE59403B1 (no)
IL (1) IL80300A (no)
NO (1) NO169127C (no)
ZA (1) ZA867783B (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993018141A1 (en) * 1992-03-02 1993-09-16 Biogen, Inc. Thrombin receptor antagonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4376071A (en) * 1980-08-21 1983-03-08 Research Corporation Mitogenic spinal cord growth factor
US4517338A (en) * 1983-06-20 1985-05-14 Chiron Corporation Multiple reactor system and method for polynucleotide synthesis
US4515920A (en) * 1984-04-30 1985-05-07 The Rockefeller University Synthesis of peptides and proteins

Also Published As

Publication number Publication date
EP0220157B1 (en) 1991-11-06
DK489086D0 (da) 1986-10-14
DK489086A (da) 1987-04-16
AU6387886A (en) 1987-04-16
NO169127B (no) 1992-02-03
FI85379C (fi) 1992-04-10
JPS62174098A (ja) 1987-07-30
JPH0689031B2 (ja) 1994-11-09
ATE69240T1 (de) 1991-11-15
NO169127C (no) 1992-05-13
EP0220157A2 (en) 1987-04-29
FI864146A (fi) 1987-04-16
US4704451A (en) 1987-11-03
FI85379B (fi) 1991-12-31
AU595249B2 (en) 1990-03-29
CA1299814C (en) 1992-04-28
EP0220157A3 (en) 1989-02-15
IL80300A (en) 1991-07-18
NO864088L (no) 1987-04-21
IE59403B1 (en) 1994-02-23
DE3682368D1 (de) 1991-12-12
ZA867783B (en) 1987-08-26
NO864088D0 (no) 1986-10-14
FI864146A0 (fi) 1986-10-14
IE862705L (en) 1987-04-15
IL80300A0 (en) 1987-01-30

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed