DK168572C - 3-aminopropanphosponsyrlingforbindelser og salte deraf, fremgangsmade til deres fremstilling samt farmaceutiske praeparater med indhold deraf - Google Patents

3-aminopropanphosponsyrlingforbindelser og salte deraf, fremgangsmade til deres fremstilling samt farmaceutiske praeparater med indhold deraf

Info

Publication number
DK168572C
DK168572C DK466185A DK466185A DK168572C DK 168572 C DK168572 C DK 168572C DK 466185 A DK466185 A DK 466185A DK 466185 A DK466185 A DK 466185A DK 168572 C DK168572 C DK 168572C
Authority
DK
Denmark
Prior art keywords
sub
salts
preparation
methods
phosphonic acid
Prior art date
Application number
DK466185A
Other languages
Danish (da)
English (en)
Other versions
DK168572B1 (da
DK466185A (da
DK466185D0 (da
Inventor
J G Dingwall
J Ehrenfreund
R G Hall
J Jack
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK466185D0 publication Critical patent/DK466185D0/da
Publication of DK168572B1 publication Critical patent/DK168572B1/da
Publication of DK466185A publication Critical patent/DK466185A/da
Application granted granted Critical
Publication of DK168572C publication Critical patent/DK168572C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/48Phosphonous acids [RP(OH)2] including [RHP(=O)(OH)]; Thiophosphonous acids including [RP(SH)2], [RHP(=S)(SH)]; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/30Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/32Esters thereof
    • C07F9/3205Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/3211Esters of acyclic saturated acids which can have further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/48Phosphonous acids [RP(OH)2] including [RHP(=O)(OH)]; Thiophosphonous acids including [RP(SH)2], [RHP(=S)(SH)]; Derivatives thereof
    • C07F9/4808Phosphonous acids [RP(OH)2] including [RHP(=O)(OH)]; Thiophosphonous acids including [RP(SH)2], [RHP(=S)(SH)]; Derivatives thereof the acid moiety containing a substituent or structure which is considered as characteristic
    • C07F9/4816Acyclic saturated acids or derivatices which can have further substituents on alkyl
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Seasonings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
DK466185A 1984-10-12 1985-10-11 3-aminopropanphosponsyrlingforbindelser og salte deraf, fremgangsmade til deres fremstilling samt farmaceutiske praeparater med indhold deraf DK168572C (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848425872A GB8425872D0 (en) 1984-10-12 1984-10-12 Chemical compounds

Publications (4)

Publication Number Publication Date
DK466185D0 DK466185D0 (da) 1985-10-11
DK168572B1 DK168572B1 (da) 1986-04-13
DK466185A DK466185A (da) 1986-04-13
DK168572C true DK168572C (da) 1994-04-25

Family

ID=10568115

Family Applications (2)

Application Number Title Priority Date Filing Date
DK466185A DK168572C (da) 1984-10-12 1985-10-11 3-aminopropanphosponsyrlingforbindelser og salte deraf, fremgangsmade til deres fremstilling samt farmaceutiske praeparater med indhold deraf
DK081093A DK169626B1 (da) 1984-10-12 1993-07-06 Substituerede 3-aminopropanphosphonsyrlingforbindelser og salte deraf

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK081093A DK169626B1 (da) 1984-10-12 1993-07-06 Substituerede 3-aminopropanphosphonsyrlingforbindelser og salte deraf

Country Status (16)

Country Link
US (4) US4656298A (enExample)
EP (1) EP0181833B1 (enExample)
JP (1) JPH0631275B2 (enExample)
AT (1) ATE53844T1 (enExample)
CA (1) CA1296736C (enExample)
DE (1) DE3577442D1 (enExample)
DK (2) DK168572C (enExample)
ES (1) ES8800250A1 (enExample)
FI (1) FI853923L (enExample)
GB (1) GB8425872D0 (enExample)
GR (1) GR852451B (enExample)
IE (1) IE58142B1 (enExample)
IL (1) IL76625A0 (enExample)
NO (1) NO854045L (enExample)
PT (1) PT81287B (enExample)
ZA (1) ZA857824B (enExample)

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US4761405A (en) * 1987-03-04 1988-08-02 Nova Pharmaceutical Corporation Antagonists of specific excitatory amino acid neurotransmitter receptors having increased potency
GB8721442D0 (en) * 1987-09-11 1987-10-21 Ciba Geigy Ag Process
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US5190933A (en) * 1987-12-04 1993-03-02 Ciba-Geigy Corporation Substituted propane-phosphinic acid compounds
US5300679A (en) * 1987-12-04 1994-04-05 Ciba-Geigy Corporation Substituted propane-phosphinic acid compounds
GB8820266D0 (en) * 1988-08-26 1988-09-28 Smith Kline French Lab Compounds
US5567840A (en) * 1989-05-13 1996-10-22 Ciba-Geigy Corporation Substituted aminoalkylphosphinic acids
US5281747A (en) * 1989-05-13 1994-01-25 Ciba-Geigy Corporation Substituted aminoalkylphosphinic acids
US5190934A (en) * 1989-06-03 1993-03-02 Ciba-Geigy Corporation P-subsituted propane-phosphinic acid compounds
IL114631A (en) * 1990-06-22 1998-12-06 Novartis Ag Anti-epileptic compositions containing gabab- antagonistic compounds
EP0767174A1 (de) * 1991-11-21 1997-04-09 Ciba-Geigy Ag Neue Aminoalkanphosphinsäuren und ihre Salze
GB9125615D0 (en) * 1991-12-02 1992-01-29 Wyeth John & Brother Ltd Amines
AU662404B2 (en) * 1992-05-08 1995-08-31 Novartis Ag Novel N-aralkyl- and N-heteroaralkyl-aminoalkanephosphinic acids
GB9304619D0 (en) * 1993-03-06 1993-04-21 Ciba Geigy Ag Esters
JP3693258B2 (ja) 1996-07-24 2005-09-07 ワーナー―ランバート・コンパニー イソブチルgabaまたはその誘導体を含有する鎮静剤
US6753324B2 (en) * 1998-07-15 2004-06-22 Hassan Jomaa Phosphorous organic compounds and their use
US7319095B2 (en) 1999-12-09 2008-01-15 Astrazeneca Ab Use of GABAB receptor agonists
SE9904508D0 (sv) 1999-12-09 1999-12-09 Astra Ab New compounds
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BR0017170A (pt) * 2000-03-20 2003-11-04 Francois Bernard Aparelho de lançamento para lançar um objeto em um fluido, clipe, navio, e, método para lançar uma carga em um fluido
US7184014B2 (en) * 2000-10-05 2007-02-27 Semiconductor Energy Laboratory Co., Ltd. Liquid crystal display device
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US7195806B2 (en) * 2003-01-17 2007-03-27 Fina Technology, Inc. High gloss polyethylene articles
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ES2515092T3 (es) 2003-12-11 2014-10-29 Sunovion Pharmaceuticals Inc. Combinación de un sedante y un modulador neurotransmisor y métodos de mejorar la calidad del sueño y de tratar la depresión
SE0401653D0 (sv) 2004-06-24 2004-06-24 Astrazeneca Ab New compounds
WO2006050471A2 (en) * 2004-11-03 2006-05-11 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
WO2006050472A2 (en) * 2004-11-03 2006-05-11 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphonous and -phosphinic acids
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
US7678363B2 (en) 2005-08-26 2010-03-16 Braincells Inc Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs
WO2007047978A2 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by pde inhibition
AU2006308889A1 (en) * 2005-10-31 2007-05-10 Braincells, Inc. GABA receptor mediated modulation of neurogenesis
JP2009521430A (ja) 2005-12-23 2009-06-04 アストラゼネカ・アクチエボラーグ Gaba−b受容体モジュレーター
EP1966154A4 (en) 2005-12-23 2011-01-26 Astrazeneca Ab IMIDAZOLE DERIVATIVES FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
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CA2651813A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
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Also Published As

Publication number Publication date
DK81093D0 (da) 1993-07-06
DK169626B1 (da) 1994-12-27
PT81287A (en) 1985-11-01
PT81287B (pt) 1988-02-17
AU593778B2 (en) 1990-02-22
EP0181833B1 (en) 1990-05-02
US4772738A (en) 1988-09-20
US5004826A (en) 1991-04-02
DK168572B1 (da) 1986-04-13
GB8425872D0 (en) 1984-11-21
US4656298A (en) 1987-04-07
ATE53844T1 (de) 1990-06-15
FI853923A0 (fi) 1985-10-09
CA1296736C (en) 1992-03-03
AU4857985A (en) 1986-04-24
GR852451B (enExample) 1986-02-11
DK81093A (da) 1993-07-06
ZA857824B (en) 1986-05-28
EP0181833A1 (en) 1986-05-21
DK466185A (da) 1986-04-13
IE58142B1 (en) 1993-07-14
ES8800250A1 (es) 1987-10-16
DE3577442D1 (de) 1990-06-07
DK466185D0 (da) 1985-10-11
JPH0631275B2 (ja) 1994-04-27
FI853923A7 (fi) 1986-04-13
IL76625A0 (en) 1986-02-28
ES547795A0 (es) 1987-10-16
JPS6193189A (ja) 1986-05-12
FI853923L (fi) 1986-04-13
US4908465A (en) 1990-03-13
IE852512L (en) 1986-04-12
NO854045L (no) 1986-04-14

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed