DK466185D0 - Substituerede 3-aminopropanphosponsyrlingforbindelser samt deres fremstilling og anvendelse - Google Patents

Substituerede 3-aminopropanphosponsyrlingforbindelser samt deres fremstilling og anvendelse

Info

Publication number
DK466185D0
DK466185D0 DK466185A DK466185A DK466185D0 DK 466185 D0 DK466185 D0 DK 466185D0 DK 466185 A DK466185 A DK 466185A DK 466185 A DK466185 A DK 466185A DK 466185 D0 DK466185 D0 DK 466185D0
Authority
DK
Denmark
Prior art keywords
sub
sup
substituted
aminopropanphosponic
preparation
Prior art date
Application number
DK466185A
Other languages
English (en)
Other versions
DK466185A (da
DK168572C (da
DK168572B1 (da
Inventor
J G Dingwall
J Ehrenfreund
R G Hall
J Jack
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK466185D0 publication Critical patent/DK466185D0/da
Application granted granted Critical
Publication of DK466185A publication Critical patent/DK466185A/da
Publication of DK168572B1 publication Critical patent/DK168572B1/da
Publication of DK168572C publication Critical patent/DK168572C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/48Phosphonous acids [RP(OH)2] including [RHP(=O)(OH)]; Thiophosphonous acids including [RP(SH)2], [RHP(=S)(SH)]; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/30Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/32Esters thereof
    • C07F9/3205Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/3211Esters of acyclic saturated acids which can have further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/48Phosphonous acids [RP(OH)2] including [RHP(=O)(OH)]; Thiophosphonous acids including [RP(SH)2], [RHP(=S)(SH)]; Derivatives thereof
    • C07F9/4808Phosphonous acids [RP(OH)2] including [RHP(=O)(OH)]; Thiophosphonous acids including [RP(SH)2], [RHP(=S)(SH)]; Derivatives thereof the acid moiety containing a substituent or structure which is considered as characteristic
    • C07F9/4816Acyclic saturated acids or derivatices which can have further substituents on alkyl
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Seasonings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
DK466185A 1984-10-12 1985-10-11 3-aminopropanphosponsyrlingforbindelser og salte deraf, fremgangsmade til deres fremstilling samt farmaceutiske praeparater med indhold deraf DK168572C (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848425872A GB8425872D0 (en) 1984-10-12 1984-10-12 Chemical compounds

Publications (4)

Publication Number Publication Date
DK466185D0 true DK466185D0 (da) 1985-10-11
DK466185A DK466185A (da) 1986-04-13
DK168572B1 DK168572B1 (da) 1986-04-13
DK168572C DK168572C (da) 1994-04-25

Family

ID=10568115

Family Applications (2)

Application Number Title Priority Date Filing Date
DK466185A DK168572C (da) 1984-10-12 1985-10-11 3-aminopropanphosponsyrlingforbindelser og salte deraf, fremgangsmade til deres fremstilling samt farmaceutiske praeparater med indhold deraf
DK081093A DK169626B1 (da) 1984-10-12 1993-07-06 Substituerede 3-aminopropanphosphonsyrlingforbindelser og salte deraf

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK081093A DK169626B1 (da) 1984-10-12 1993-07-06 Substituerede 3-aminopropanphosphonsyrlingforbindelser og salte deraf

Country Status (16)

Country Link
US (4) US4656298A (da)
EP (1) EP0181833B1 (da)
JP (1) JPH0631275B2 (da)
AT (1) ATE53844T1 (da)
CA (1) CA1296736C (da)
DE (1) DE3577442D1 (da)
DK (2) DK168572C (da)
ES (1) ES8800250A1 (da)
FI (1) FI853923L (da)
GB (1) GB8425872D0 (da)
GR (1) GR852451B (da)
IE (1) IE58142B1 (da)
IL (1) IL76625A0 (da)
NO (1) NO854045L (da)
PT (1) PT81287B (da)
ZA (1) ZA857824B (da)

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US4761405A (en) * 1987-03-04 1988-08-02 Nova Pharmaceutical Corporation Antagonists of specific excitatory amino acid neurotransmitter receptors having increased potency
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GB8728483D0 (en) * 1987-12-04 1988-01-13 Ciba Geigy Ag Chemical compounds
GB8820266D0 (en) * 1988-08-26 1988-09-28 Smith Kline French Lab Compounds
US5567840A (en) * 1989-05-13 1996-10-22 Ciba-Geigy Corporation Substituted aminoalkylphosphinic acids
US5281747A (en) * 1989-05-13 1994-01-25 Ciba-Geigy Corporation Substituted aminoalkylphosphinic acids
US5190934A (en) * 1989-06-03 1993-03-02 Ciba-Geigy Corporation P-subsituted propane-phosphinic acid compounds
IL98502A (en) * 1990-06-22 1998-04-05 Ciba Geigy Ag History of Aminoalkene Phosphine Acid, Process for Their Preparation and Pharmaceutical Preparations Containing Them
EP0767174A1 (de) * 1991-11-21 1997-04-09 Ciba-Geigy Ag Neue Aminoalkanphosphinsäuren und ihre Salze
GB9125615D0 (en) * 1991-12-02 1992-01-29 Wyeth John & Brother Ltd Amines
AU662404B2 (en) * 1992-05-08 1995-08-31 Novartis Ag Novel N-aralkyl- and N-heteroaralkyl-aminoalkanephosphinic acids
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WO1998003167A1 (en) 1996-07-24 1998-01-29 Warner-Lambert Company Isobutylgaba and its derivatives for the treatment of pain
US6753324B2 (en) * 1998-07-15 2004-06-22 Hassan Jomaa Phosphorous organic compounds and their use
US7319095B2 (en) 1999-12-09 2008-01-15 Astrazeneca Ab Use of GABAB receptor agonists
SE9904507D0 (sv) 1999-12-09 1999-12-09 Astra Ab New compounds
SE9904508D0 (sv) 1999-12-09 1999-12-09 Astra Ab New compounds
JP2003528002A (ja) * 2000-03-20 2003-09-24 バーナード、フランソワ 水中に物体を配置する装置および方法
US7184014B2 (en) * 2000-10-05 2007-02-27 Semiconductor Energy Laboratory Co., Ltd. Liquid crystal display device
AR033779A1 (es) 2001-06-08 2004-01-07 Astrazeneca Ab Compuestos utiles en la enfermedad de reflujo
JP2005531506A (ja) 2002-03-01 2005-10-20 メルク エンド カムパニー インコーポレーテッド Edg受容体作動薬としてのアミノアルキルホスホネートおよび関連化合物
US7195806B2 (en) * 2003-01-17 2007-03-27 Fina Technology, Inc. High gloss polyethylene articles
DE10356410A1 (de) * 2003-11-24 2005-06-23 Bioagency Ag Phosphororganische Verbindungen und deren Verwendung
PL1691811T3 (pl) 2003-12-11 2014-12-31 Sunovion Pharmaceuticals Inc Skojarzenie leku uspokajającego i modulatora neuroprzekaźnikowego oraz sposoby poprawy jakości snu i leczenia depresji
SE0401653D0 (sv) 2004-06-24 2004-06-24 Astrazeneca Ab New compounds
US7566738B2 (en) * 2004-11-03 2009-07-28 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
WO2006050472A2 (en) * 2004-11-03 2006-05-11 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphonous and -phosphinic acids
EP2258358A3 (en) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
EP2275095A3 (en) 2005-08-26 2011-08-17 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
JP2009512711A (ja) 2005-10-21 2009-03-26 ブレインセルス,インコーポレイティド Pde阻害による神経新生の調節
CA2625210A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
CN101341130A (zh) 2005-12-23 2009-01-07 阿斯利康(瑞典)有限公司 用于治疗胃肠障碍的咪唑衍生物
CA2632021A1 (en) 2005-12-23 2007-06-28 Astrazeneca Ab Gaba-b receptor modulators
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
AU2007249399A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
JP2009536667A (ja) 2006-05-09 2009-10-15 ブレインセルス,インコーポレイティド 5ht受容体介在性の神経新生
KR20090064418A (ko) 2006-09-08 2009-06-18 브레인셀즈 인코퍼레이션 4-아실아미노피리딘 유도체 포함 조합물
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Also Published As

Publication number Publication date
CA1296736C (en) 1992-03-03
US4772738A (en) 1988-09-20
DK466185A (da) 1986-04-13
US4908465A (en) 1990-03-13
IE58142B1 (en) 1993-07-14
PT81287A (en) 1985-11-01
IE852512L (en) 1986-04-12
GB8425872D0 (en) 1984-11-21
IL76625A0 (en) 1986-02-28
US5004826A (en) 1991-04-02
JPH0631275B2 (ja) 1994-04-27
FI853923A0 (fi) 1985-10-09
NO854045L (no) 1986-04-14
AU4857985A (en) 1986-04-24
US4656298A (en) 1987-04-07
ATE53844T1 (de) 1990-06-15
DK81093D0 (da) 1993-07-06
DE3577442D1 (de) 1990-06-07
ES547795A0 (es) 1987-10-16
EP0181833B1 (en) 1990-05-02
DK169626B1 (da) 1994-12-27
DK168572C (da) 1994-04-25
PT81287B (pt) 1988-02-17
FI853923L (fi) 1986-04-13
JPS6193189A (ja) 1986-05-12
ES8800250A1 (es) 1987-10-16
DK81093A (da) 1993-07-06
AU593778B2 (en) 1990-02-22
EP0181833A1 (en) 1986-05-21
DK168572B1 (da) 1986-04-13
ZA857824B (en) 1986-05-28
GR852451B (da) 1986-02-11

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Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed