DK167925B1 - 9-substitueret guanin-monohydrat, fremgangsmaade til fremstilling heraf, farmaceutisk praeparat, monohydrat til brug som terapeutisk aktivt middel, monohydrat til brug til behandling af virusinfektioner og anvendelse af et monohydrat til brug ved fremstilling af et medikament - Google Patents

9-substitueret guanin-monohydrat, fremgangsmaade til fremstilling heraf, farmaceutisk praeparat, monohydrat til brug som terapeutisk aktivt middel, monohydrat til brug til behandling af virusinfektioner og anvendelse af et monohydrat til brug ved fremstilling af et medikament Download PDF

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Publication number
DK167925B1
DK167925B1 DK356686A DK356686A DK167925B1 DK 167925 B1 DK167925 B1 DK 167925B1 DK 356686 A DK356686 A DK 356686A DK 356686 A DK356686 A DK 356686A DK 167925 B1 DK167925 B1 DK 167925B1
Authority
DK
Denmark
Prior art keywords
monohydrate
compound
treatment
virusin
formula
Prior art date
Application number
DK356686A
Other languages
Danish (da)
English (en)
Other versions
DK356686A (da
DK356686D0 (da
Inventor
Michael Raymond Harnden
Richard Lewis Jarvest
Graham Richard Geen
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858519011A external-priority patent/GB8519011D0/en
Priority claimed from GB858530491A external-priority patent/GB8530491D0/en
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of DK356686D0 publication Critical patent/DK356686D0/da
Publication of DK356686A publication Critical patent/DK356686A/da
Application granted granted Critical
Publication of DK167925B1 publication Critical patent/DK167925B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK356686A 1985-07-27 1986-07-25 9-substitueret guanin-monohydrat, fremgangsmaade til fremstilling heraf, farmaceutisk praeparat, monohydrat til brug som terapeutisk aktivt middel, monohydrat til brug til behandling af virusinfektioner og anvendelse af et monohydrat til brug ved fremstilling af et medikament DK167925B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB858519011A GB8519011D0 (en) 1985-07-27 1985-07-27 Chemical compound
GB8519011 1985-07-27
GB8530491 1985-12-11
GB858530491A GB8530491D0 (en) 1985-12-11 1985-12-11 Chemical compound

Publications (3)

Publication Number Publication Date
DK356686D0 DK356686D0 (da) 1986-07-25
DK356686A DK356686A (da) 1987-01-28
DK167925B1 true DK167925B1 (da) 1994-01-03

Family

ID=26289562

Family Applications (1)

Application Number Title Priority Date Filing Date
DK356686A DK167925B1 (da) 1985-07-27 1986-07-25 9-substitueret guanin-monohydrat, fremgangsmaade til fremstilling heraf, farmaceutisk praeparat, monohydrat til brug som terapeutisk aktivt middel, monohydrat til brug til behandling af virusinfektioner og anvendelse af et monohydrat til brug ved fremstilling af et medikament

Country Status (13)

Country Link
US (1) US4942166A (es)
EP (1) EP0216459B1 (es)
JP (1) JPH0670057B2 (es)
AU (1) AU596366B2 (es)
CA (1) CA1262132A (es)
DE (1) DE3671227D1 (es)
DK (1) DK167925B1 (es)
ES (1) ES2000759A6 (es)
GR (1) GR861963B (es)
IE (1) IE58639B1 (es)
MX (1) MX165149B (es)
NZ (1) NZ216978A (es)
PT (1) PT83073B (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3485225D1 (de) * 1983-08-18 1991-12-05 Beecham Group Plc Antivirale guanin-derivate.
IL73682A (en) * 1983-12-20 1991-08-16 Medivir Ab Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation
US4966895A (en) * 1989-02-02 1990-10-30 Merck & Co. Inc. Cyclic monophosphates of purine and pyrimidine acyclonucleosides as anti-retroviral agents
GB8904855D0 (en) * 1989-03-03 1989-04-12 Beecham Group Plc Pharmaceutical treatment
US6207650B1 (en) * 1989-05-15 2001-03-27 Bristol-Myers Squibb Company Antiviral, highly water soluble, stable, crystalline salts of 2′, 3′-dideoxyinosine, 2′, 3′-dideoxy-2′, 3′-didehydrothymidine and 2′, 3′-dideoxy-2′-fluoroinosine
GB8922076D0 (en) * 1989-09-28 1989-11-15 Beecham Group Plc Novel process
US6469015B1 (en) 1990-01-26 2002-10-22 Novartis International Pharmaceutical Ltd Pharmaceutical formulation
GB9001886D0 (en) * 1990-01-26 1990-03-28 Beecham Group Plc Pharmaceutical formulation
GB9015051D0 (en) * 1990-07-07 1990-08-29 Beecham Group Plc Pharmaceutical treatment
US5674869A (en) * 1990-07-07 1997-10-07 Beecham Group Plc Pharmaceutical treatment
US5670506A (en) * 1993-04-05 1997-09-23 Cell Therapeutics, Inc. Halogen, isothiocyanate or azide substituted xanthines
US6124304A (en) * 1993-10-05 2000-09-26 Smithkline Beecham Plc Penciclovir for the treatment of zoster associated pain
GB9326177D0 (en) * 1993-12-22 1994-02-23 Smithkline Beecham Plc Pharmaceuticals
US6683084B1 (en) 1993-11-12 2004-01-27 Novartis International Pharmaceutical Ltd. Use of 2-amino purine derivatives for the treatment and prophylaxis of human herpes virus 6 infections
GB9323403D0 (en) * 1993-11-12 1994-01-05 Smithkline Beecham Plc Pharmaceuticals
GB9323404D0 (en) * 1993-11-12 1994-01-05 Smithkline Beecham Plc Pharmaceuticals
GB9504497D0 (en) * 1995-03-07 1995-04-26 Smithkline Beecham Plc Pharmaceuticals
PT102030B (pt) * 1996-07-20 1999-04-30 Smithkline Beecham Plc Processo para a apreparacao dos compostos penciclovir ou famciclovir que sao utesi como agentes antivirais
GB9615253D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
GB9615276D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
US6824793B1 (en) 1998-06-01 2004-11-30 Chiron Corporation Use of hyaluronic acid polymers for mucosal delivery of vaccine antigens and adjuvants
US6107303A (en) * 1999-03-15 2000-08-22 Demarco; Charlene C. Treatment of Epstein Barr infection
WO2004018470A2 (en) * 2002-08-26 2004-03-04 Teva Pharmaceutical Industries Ltd. Crystalline solid famciclovir forms i, ii, iii and preparation thereof
AU2006230269A1 (en) 2005-03-30 2006-10-05 Novartis Ag Penciclovir or famciclovir for the treatment of recurrent genital herpes with a one-day application
CN111377926B (zh) * 2018-12-29 2024-06-07 凯默斯医药科技(上海)有限公司 一种喷昔洛韦晶型及其制备方法
CN110627793B (zh) * 2019-09-10 2020-08-28 天津理工大学 一种喷昔洛韦与3,5-二羟基苯甲酸共晶及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU577303B2 (en) * 1983-08-18 1988-09-22 Novartis International Pharmaceutical Ltd 9-substituted-2-amino purines
DE3485225D1 (de) 1983-08-18 1991-12-05 Beecham Group Plc Antivirale guanin-derivate.
IL73682A (en) * 1983-12-20 1991-08-16 Medivir Ab Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation
EP0152316B1 (en) * 1984-01-26 1989-07-26 Merck & Co. Inc. Substituted butyl guanines and their utilization in antiviral compositions
US4642346A (en) * 1985-06-24 1987-02-10 Syntex (U.S.A.) Inc. Anhydrous crystalline 9-(1,3-dihydroxy-2-propoxymethyl)guanine

Also Published As

Publication number Publication date
JPS6236381A (ja) 1987-02-17
DK356686A (da) 1987-01-28
DE3671227D1 (de) 1990-06-21
US4942166A (en) 1990-07-17
MX165149B (es) 1992-10-28
DK356686D0 (da) 1986-07-25
EP0216459A1 (en) 1987-04-01
AU6055786A (en) 1987-01-29
AU596366B2 (en) 1990-05-03
IE58639B1 (en) 1993-10-20
ES2000759A6 (es) 1988-03-16
PT83073B (pt) 1989-02-28
PT83073A (en) 1986-08-01
GR861963B (en) 1986-11-26
JPH0670057B2 (ja) 1994-09-07
EP0216459B1 (en) 1990-05-16
IE861984L (en) 1987-01-27
NZ216978A (en) 1990-01-29
CA1262132A (en) 1989-10-03

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired