DK1678182T3 - Fremgangsmåde til fremstilling af substituerede 5-amino-pyrazolo[4,3-E]-1,2,4-triazolo-[1,5-C]pyrimidiner - Google Patents

Fremgangsmåde til fremstilling af substituerede 5-amino-pyrazolo[4,3-E]-1,2,4-triazolo-[1,5-C]pyrimidiner

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Publication number
DK1678182T3
DK1678182T3 DK04796445T DK04796445T DK1678182T3 DK 1678182 T3 DK1678182 T3 DK 1678182T3 DK 04796445 T DK04796445 T DK 04796445T DK 04796445 T DK04796445 T DK 04796445T DK 1678182 T3 DK1678182 T3 DK 1678182T3
Authority
DK
Denmark
Prior art keywords
triazolo
pyrazolo
pyrimidines
amino
substituted
Prior art date
Application number
DK04796445T
Other languages
Danish (da)
English (en)
Inventor
Shen-Chun Kuo
David Jieh-Shyh Tsai
Loc Thanh Tran
Pengyi Zhang
Andrew D Jones
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of DK1678182T3 publication Critical patent/DK1678182T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK04796445T 2003-10-28 2004-10-26 Fremgangsmåde til fremstilling af substituerede 5-amino-pyrazolo[4,3-E]-1,2,4-triazolo-[1,5-C]pyrimidiner DK1678182T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51505103P 2003-10-28 2003-10-28
PCT/US2004/035472 WO2005044819A1 (en) 2003-10-28 2004-10-26 Process for preparing substituted 5-amino-pyrazolo-[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines

Publications (1)

Publication Number Publication Date
DK1678182T3 true DK1678182T3 (da) 2007-06-04

Family

ID=34572798

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04796445T DK1678182T3 (da) 2003-10-28 2004-10-26 Fremgangsmåde til fremstilling af substituerede 5-amino-pyrazolo[4,3-E]-1,2,4-triazolo-[1,5-C]pyrimidiner

Country Status (19)

Country Link
US (4) US7223861B2 (de)
EP (1) EP1678182B1 (de)
JP (2) JP4782693B2 (de)
CN (2) CN1898246B (de)
AR (1) AR046560A1 (de)
AT (1) ATE353331T1 (de)
CA (1) CA2543431A1 (de)
CY (1) CY1106393T1 (de)
DE (1) DE602004004677T2 (de)
DK (1) DK1678182T3 (de)
ES (1) ES2278353T3 (de)
HK (1) HK1086008A1 (de)
HR (1) HRP20070063T3 (de)
MX (1) MXPA06004722A (de)
PL (1) PL1678182T3 (de)
PT (1) PT1678182E (de)
SI (1) SI1678182T1 (de)
WO (1) WO2005044819A1 (de)
ZA (1) ZA200603307B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI288137B (en) * 2000-05-26 2007-10-11 Schering Corp Adenosine A2a receptor antagonists
DK1678182T3 (da) * 2003-10-28 2007-06-04 Schering Corp Fremgangsmåde til fremstilling af substituerede 5-amino-pyrazolo[4,3-E]-1,2,4-triazolo-[1,5-C]pyrimidiner
ATE556712T1 (de) * 2005-06-07 2012-05-15 Kyowa Hakko Kirin Co Ltd A2a antagonisten zur behandlung von motorischen störungen
US8598343B2 (en) * 2009-08-07 2013-12-03 Merck Sharp & Dohme Corp. Process for preparing a 2-alkynyl substituted 5-amino-pyrazolo-[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine
US20110144049A1 (en) * 2009-10-21 2011-06-16 Serebruany Victor L Treating Cardiac Arrhythmias, Heart Failure, Peripheral Artery Disease and Stroke with Cyclopentyl-Triazolo-Pyrimidine or Derivative Thereof
WO2013024474A1 (en) * 2011-08-18 2013-02-21 Mapi Phrarma Ltd. Polymorphs of preladenant
JPWO2013168196A1 (ja) 2012-05-10 2015-12-24 ユニテクノ株式会社 半導体搬送テスト治具
WO2016049414A1 (en) * 2014-09-26 2016-03-31 F. Hoffmann-La Roche Ag PROCESSES FOR PREPARING (CYCLOPENTYL[d]PYRIMIDIN-4-YL)PIPERAZINE COMPOUNDS
CR20210271A (es) 2018-11-30 2021-07-14 Merck Sharp & Dohme Derivados de amino triazolo quinazolina 9-sustituidos como antagonistas del receptor de adenosina, composiciones farmacéuticas y su uso

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4039733A1 (de) * 1990-12-13 1992-06-17 Basf Ag Substituierte 5-aminopyrazole
IT1264901B1 (it) * 1993-06-29 1996-10-17 Schering Plough S P A Analoghi eterociclici di 1,2,4-triazolo(15-c)pirimidine ad attivita' antagonista per il recettore a2 dell'adenosina
US6448253B1 (en) * 1998-09-16 2002-09-10 King Pharmaceuticals Research And Development, Inc. Adenosine A3 receptor modulators
TWI288137B (en) * 2000-05-26 2007-10-11 Schering Corp Adenosine A2a receptor antagonists
EP1364953A4 (de) * 2001-02-05 2004-06-09 Otsuka Pharma Co Ltd Triazolochinazolin- und pyrazolotriazolopyrimidinderivate, medizinische zusammensetzungen, mittel mit adenosin-a3-rezeptoraffinität, mittel, die den augeninnendruck senken, zubereitungen zur prävention und behandlung von glaukom und verfahren zur senkung des augeninnendrucks"
ES2254671T3 (es) * 2001-05-01 2006-06-16 Astellas Pharma Inc. Compuestos de cefem.
CA2468649C (en) * 2001-11-30 2009-03-10 Schering Corporation Adenosine a2a receptor antagonists
DK1678182T3 (da) * 2003-10-28 2007-06-04 Schering Corp Fremgangsmåde til fremstilling af substituerede 5-amino-pyrazolo[4,3-E]-1,2,4-triazolo-[1,5-C]pyrimidiner
JP2007513091A (ja) * 2003-12-01 2007-05-24 シェーリング　コーポレイション 置換された５−アミノ−ピラゾロ−［４，３−ｅ］−１，２，４−トリアゾロ［１，５−ｃ］ピリミジンを調製するための方法

Also Published As

Publication number Publication date
US20090326241A1 (en) 2009-12-31
AR046560A1 (es) 2005-12-14
DE602004004677T2 (de) 2007-11-15
WO2005044819A1 (en) 2005-05-19
EP1678182A1 (de) 2006-07-12
US20050090492A1 (en) 2005-04-28
JP2011116795A (ja) 2011-06-16
ES2278353T3 (es) 2007-08-01
DE602004004677D1 (de) 2007-03-22
CN101899050A (zh) 2010-12-01
CN1898246A (zh) 2007-01-17
US7223861B2 (en) 2007-05-29
PT1678182E (pt) 2007-04-30
HK1086008A1 (en) 2006-09-08
US20070203340A1 (en) 2007-08-30
JP4782693B2 (ja) 2011-09-28
US20090005559A1 (en) 2009-01-01
HRP20070063T3 (en) 2007-04-30
ZA200603307B (en) 2008-07-30
US7601833B2 (en) 2009-10-13
CY1106393T1 (el) 2011-10-12
JP2007509948A (ja) 2007-04-19
ATE353331T1 (de) 2007-02-15
US7439361B2 (en) 2008-10-21
CN1898246B (zh) 2010-10-27
SI1678182T1 (sl) 2007-06-30
MXPA06004722A (es) 2006-07-05
EP1678182B1 (de) 2007-02-07
CA2543431A1 (en) 2005-05-19
PL1678182T3 (pl) 2007-05-31

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