DK166828B1 - Mono-sialo gangliosid gm1p, praeparater indeholdende dette samt anvendelse deraf til fremstilling af et laegemiddel - Google Patents

Mono-sialo gangliosid gm1p, praeparater indeholdende dette samt anvendelse deraf til fremstilling af et laegemiddel Download PDF

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Publication number
DK166828B1
DK166828B1 DK356984A DK356984A DK166828B1 DK 166828 B1 DK166828 B1 DK 166828B1 DK 356984 A DK356984 A DK 356984A DK 356984 A DK356984 A DK 356984A DK 166828 B1 DK166828 B1 DK 166828B1
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DK
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Prior art keywords
ganglioside
gm1p
mono
sialo
aqueous solution
Prior art date
Application number
DK356984A
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Danish (da)
English (en)
Other versions
DK356984D0 (da
DK356984A (da
Inventor
Ezio Tubaro
Giovanni Cavallo
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of DK356984D0 publication Critical patent/DK356984D0/da
Publication of DK356984A publication Critical patent/DK356984A/da
Application granted granted Critical
Publication of DK166828B1 publication Critical patent/DK166828B1/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK356984A 1983-07-21 1984-07-20 Mono-sialo gangliosid gm1p, praeparater indeholdende dette samt anvendelse deraf til fremstilling af et laegemiddel DK166828B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT48724/83A IT1168205B (it) 1983-07-21 1983-07-21 Derivato di monsialo ganglioside dotato di attivita' antibatterica, antifungina ed antitumorale, composizioni che lo contengono e procedimento per la loro preparazione
IT4872483 1983-07-21

Publications (3)

Publication Number Publication Date
DK356984D0 DK356984D0 (da) 1984-07-20
DK356984A DK356984A (da) 1985-01-22
DK166828B1 true DK166828B1 (da) 1993-07-19

Family

ID=11268264

Family Applications (1)

Application Number Title Priority Date Filing Date
DK356984A DK166828B1 (da) 1983-07-21 1984-07-20 Mono-sialo gangliosid gm1p, praeparater indeholdende dette samt anvendelse deraf til fremstilling af et laegemiddel

Country Status (9)

Country Link
US (2) US4728641A (hu)
EP (1) EP0136438B1 (hu)
JP (1) JPS6084296A (hu)
AT (1) ATE75480T1 (hu)
DE (1) DE3485680D1 (hu)
DK (1) DK166828B1 (hu)
ES (1) ES8603191A1 (hu)
HU (1) HU198091B (hu)
IT (1) IT1168205B (hu)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH660557A5 (fr) * 1984-10-26 1987-05-15 Nestle Sa Composition anti-bacterienne et procede de preparation de ses constituants actifs.
DK17885D0 (da) * 1985-01-14 1985-01-14 Karlsson Karl Anders Antiviralt middel
JPH0653764B2 (ja) * 1985-07-31 1994-07-20 三井東圧化学株式会社 モノシアロガングリオシドの製造法
EP0249008B1 (de) * 1986-05-09 1993-09-15 Pulverer, Gerhard, Prof. Dr.Dr.h.c. Verwendung von spezifischen Monosacchariden zur Herstellung eines Arzneimittels zur Verhinderung von Metastasen maligner Tumore
IT1208751B (it) * 1986-06-30 1989-07-10 Fidia Farmaceutici Possibile uso dei gangliosidi esogeni in malattie tumorali come fattore protettivo contro la neurotossicita' da farmaci antitumorali
EP0508493A1 (en) * 1986-08-06 1992-10-14 Mect Corporation Ganglioside related compounds and method of producing the same
IT1212041B (it) * 1987-11-02 1989-11-08 Fidia Farmaceutici Gangliosidi esteri interni come agenti terapeutici capaci di eliminare il dolore nelle neuropatie periferiche
AU7153991A (en) * 1989-12-13 1991-07-18 Glycomed Incorporated Synthesis of rotavirus receptor saccharides
AU6902691A (en) * 1989-12-13 1991-07-18 Glycomed Incorporated Synthetic receptor molecules recognizable by a rotavirus
WO1993002686A1 (en) * 1991-07-31 1993-02-18 The Regents Of The University Of California Gangliosides with immunosuppressive ceramide moieties
US5936076A (en) * 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives
DE4204907A1 (de) * 1992-02-14 1993-08-19 Reutter Werner Neuartige glykokonjugate mit n-substituierten neuraminsaeuren als mittel zur stimulierung des immunsystems
TW261533B (hu) * 1992-07-16 1995-11-01 Kirin Brewery
DE69328435T2 (de) * 1992-10-22 2000-09-14 Kirin Brewery Neues sphingolglycolipid und verwendung davon
KR100281265B1 (ko) * 1993-04-15 2001-02-01 마나배 게이사꾸 신규한 스핀고당지질 및 그의 사용
DE19602108A1 (de) * 1996-01-22 1997-07-24 Beiersdorf Ag Gegen Bakterien, Parasiten, Protozoen, Mycota und Viren wirksame Substanzen
US5747476A (en) 1996-07-17 1998-05-05 Mortar & Pestle Veterinary Pharmacy, Inc. Treatment of equine protozoal myeloencephalitis
DE19643585A1 (de) * 1996-10-22 1998-04-23 Beiersdorf Ag Antiadhäsive Sphingolipide
WO2002018401A2 (en) * 2000-09-01 2002-03-07 Neuronyx, Inc. Novel synthetic gangliosides
AU2001288671A1 (en) * 2000-09-01 2002-03-13 Neuronyx, Inc. Novel synthetic gangliosides
US9969980B2 (en) * 2001-09-21 2018-05-15 Garnet Biotherapeutics Cell populations which co-express CD49c and CD90
EP1358910A1 (de) * 2002-05-02 2003-11-05 B.R.A.H.M.S Aktiengesellschaft Verfahren und Mittel zur Prävention, Hemmung und Therapie von Krebserkrankungen
EP1367395A1 (de) * 2002-05-02 2003-12-03 B.R.A.H.M.S Aktiengesellschaft Diagnose von Neoplasmen mit Hilfe von anti-Gangliosid-Antikörpern
US9969977B2 (en) * 2002-09-20 2018-05-15 Garnet Biotherapeutics Cell populations which co-express CD49c and CD90
EP1603932B1 (en) 2003-03-06 2012-10-03 Seneb Biosciences Inc. Methods and compositions for the enzymatic synthesis of gangliosides
JP4965063B2 (ja) * 2004-05-07 2012-07-04 雪印メグミルク株式会社 口腔内細菌叢改善剤、抗菌剤及び生育促進剤。
WO2006032111A1 (en) 2004-09-23 2006-03-30 National Ventilation Laboratory Pty Ltd Hybrid ventilator
CN101835891A (zh) * 2007-06-15 2010-09-15 加内特生物治疗学股份有限公司 运用体外培养增殖的自我更新型集落形成细胞治疗疾病和功能紊乱症
US20090239834A1 (en) * 2008-03-21 2009-09-24 Braincells, Inc. Mcc-257 modulation of neurogenesis
DE102010024041A1 (de) * 2010-05-16 2013-04-04 Alfred Kroll Symtomfreiheit der Atemwege

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT295036B (de) * 1968-11-29 1971-12-27 Leikola Erkki E Verfahren zur Herstellung von neuen Produkten tierischen Ursprungs
US4125492A (en) * 1974-05-31 1978-11-14 Pedro Cuatrecasas Affinity chromatography of vibrio cholerae enterotoxin-ganglioside polysaccharide and the biological effects of ganglioside-containing soluble polymers
FR2478104B1 (fr) * 1980-03-17 1986-08-08 Merieux Inst Nouveaux derives de gangliosides, leur preparation et leur application
WO1981003175A1 (en) * 1980-05-09 1981-11-12 H Leffler Carbohydrate derivatives for inhibiting bacterial adherence
CH658458A5 (fr) * 1981-12-17 1986-11-14 Lucchini Lab Sa Procede pour l'obtention du lacto-n-norhexaosyl ceramide.

Also Published As

Publication number Publication date
EP0136438A3 (en) 1987-05-13
ATE75480T1 (de) 1992-05-15
HUT35690A (en) 1985-07-29
DK356984D0 (da) 1984-07-20
DK356984A (da) 1985-01-22
ES534494A0 (es) 1985-12-01
IT1168205B (it) 1987-05-20
JPS6084296A (ja) 1985-05-13
IT8348724A0 (it) 1983-07-21
EP0136438B1 (en) 1992-04-29
EP0136438A2 (en) 1985-04-10
US4728641A (en) 1988-03-01
DE3485680D1 (de) 1992-06-04
HU198091B (en) 1989-07-28
US4831021A (en) 1989-05-16
ES8603191A1 (es) 1985-12-01

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed