DK1664770T3 - Fremgangsmåde til bestemmelse af indvirkningen af en multikomponent-syntetisk-produkt-blanding på den biologiske profil for sygdom inden for en gruppe af levende systemer og udviklingen af nye kombinatoriske interventioner - Google Patents

Fremgangsmåde til bestemmelse af indvirkningen af en multikomponent-syntetisk-produkt-blanding på den biologiske profil for sygdom inden for en gruppe af levende systemer og udviklingen af nye kombinatoriske interventioner

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Publication number
DK1664770T3
DK1664770T3 DK04774923T DK04774923T DK1664770T3 DK 1664770 T3 DK1664770 T3 DK 1664770T3 DK 04774923 T DK04774923 T DK 04774923T DK 04774923 T DK04774923 T DK 04774923T DK 1664770 T3 DK1664770 T3 DK 1664770T3
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Prior art keywords
disease
biological profile
impact
determining
group
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DK04774923T
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Danish (da)
English (en)
Inventor
Mei Wang
Renger Witkamp
Der Greef Jan Van
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Tno
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Publication of DK1664770T3 publication Critical patent/DK1664770T3/da

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5023Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082Supracellular entities, e.g. tissue, organisms
    • G01N33/5088Supracellular entities, e.g. tissue, organisms of vertebrates
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H70/00ICT specially adapted for the handling or processing of medical references
    • G16H70/60ICT specially adapted for the handling or processing of medical references relating to pathologies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2550/00Electrophoretic profiling, e.g. for proteome analysis
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Databases & Information Systems (AREA)
  • Data Mining & Analysis (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
DK04774923T 2003-09-05 2004-09-03 Fremgangsmåde til bestemmelse af indvirkningen af en multikomponent-syntetisk-produkt-blanding på den biologiske profil for sygdom inden for en gruppe af levende systemer og udviklingen af nye kombinatoriske interventioner DK1664770T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03077804A EP1512970A1 (de) 2003-09-05 2003-09-05 Verfahren zur Bestimmung der Wirkung einer Zusammensetzung auf das Profil einer Krankheit
PCT/NL2004/000617 WO2005024421A1 (en) 2003-09-05 2004-09-03 Method for determining the impact of a multicomponent synthetic product mixture on the biological profile of a disease within a group of living systems and the development of new combinatorial interventions

Publications (1)

Publication Number Publication Date
DK1664770T3 true DK1664770T3 (da) 2008-03-25

Family

ID=34130247

Family Applications (2)

Application Number Title Priority Date Filing Date
DK04774923T DK1664770T3 (da) 2003-09-05 2004-09-03 Fremgangsmåde til bestemmelse af indvirkningen af en multikomponent-syntetisk-produkt-blanding på den biologiske profil for sygdom inden for en gruppe af levende systemer og udviklingen af nye kombinatoriske interventioner
DK04774922T DK1664767T3 (da) 2003-09-05 2004-09-03 Fremgangsmåde til bestemmelse af indvirkningen af en af flere komponenter bestående naturproduktblanding på den biologiske profil for en sygdom inden for en gruppe af levende systemer og udvikling og kvalitetskontrol af medicin baseret på naturprodukter

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK04774922T DK1664767T3 (da) 2003-09-05 2004-09-03 Fremgangsmåde til bestemmelse af indvirkningen af en af flere komponenter bestående naturproduktblanding på den biologiske profil for en sygdom inden for en gruppe af levende systemer og udvikling og kvalitetskontrol af medicin baseret på naturprodukter

Country Status (10)

Country Link
US (2) US20070020180A1 (de)
EP (3) EP1512970A1 (de)
JP (2) JP2007508603A (de)
CN (2) CN1875273A (de)
AT (2) ATE378593T1 (de)
DE (2) DE602004010154T2 (de)
DK (2) DK1664770T3 (de)
EA (1) EA011959B1 (de)
ES (2) ES2297475T3 (de)
WO (2) WO2005024421A1 (de)

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US7425700B2 (en) 2003-05-22 2008-09-16 Stults John T Systems and methods for discovery and analysis of markers
EP1512970A1 (de) * 2003-09-05 2005-03-09 Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO Verfahren zur Bestimmung der Wirkung einer Zusammensetzung auf das Profil einer Krankheit
US7729789B2 (en) * 2004-05-04 2010-06-01 Fisher-Rosemount Systems, Inc. Process plant monitoring based on multivariate statistical analysis and on-line process simulation
US20080183101A1 (en) * 2006-08-17 2008-07-31 Jonathan Richard Stonehouse Salivary analysis
KR101459805B1 (ko) 2007-03-30 2014-11-07 9898 리미티드 천연 산물 개발을 위한 약제 플랫폼 기법
DE102008011013B4 (de) * 2008-02-25 2014-11-13 Mevitec Gmbh Verfahren und Einrichtung zur komplexen Stoffwechselanalyse
KR101144237B1 (ko) * 2009-12-29 2012-05-11 한국기초과학지원연구원 고분해능 질량분석법과 약리활성검사를 이용한 천연물의 약리 활성물질 발굴 방법
MY181093A (en) 2011-03-02 2020-12-17 Berg Llc Interrogatory cell-based assays and uses thereof
MX357392B (es) * 2012-04-02 2018-07-06 Berg Llc Ensayos basados en interrogatorios celulares y uso de los mismos.
JP2014020831A (ja) * 2012-07-13 2014-02-03 Kyoto Univ 混合物試料の属性を識別する方法及び装置
US20150019189A1 (en) * 2013-07-01 2015-01-15 Counterpoint Health Solutions, Inc. Systems biology approach to therapy
WO2016039348A1 (ja) * 2014-09-10 2016-03-17 一般財団法人ニッセンケン品質評価センター タンパク質繊維の鑑別方法
CN107111603A (zh) 2014-09-11 2017-08-29 博格有限责任公司 基于患者数据的用于健康护理诊断和治疗的贝叶斯因果关系网络模型
CN109115904B (zh) * 2018-07-25 2021-02-02 山西广誉远国药有限公司 一种定坤丹uplc指纹图谱的构建方法及其应用
CA3146525A1 (en) 2019-08-05 2021-02-11 William Manning Systems and methods for sample preparation, data generation, and protein corona analysis
CN111180007A (zh) * 2019-12-03 2020-05-19 深圳市开物成务中医药科技有限公司 一种安全、有效、高质量中药开发平台系统及实现方法
CN111060640A (zh) * 2019-12-27 2020-04-24 深圳市开物成务中医药科技有限公司 测定与胰岛素耐受性相关的血脂谱的方法、应用及装置

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US5885782A (en) * 1994-09-13 1999-03-23 Nce Pharmaceuticals, Inc. Synthetic antibiotics
US5563043A (en) * 1994-10-24 1996-10-08 Spiral Biotech, Inc. Method for measuring the bactericidal and bacteriostatic effects of antimicrobial agents
US6379714B1 (en) * 1995-04-14 2002-04-30 Pharmaprint, Inc. Pharmaceutical grade botanical drugs
WO1997020076A1 (en) * 1995-11-29 1997-06-05 Nexstar Pharmaceuticals, Inc. Methods for optimizing multicomponent formulations
JP3978529B2 (ja) * 1998-08-03 2007-09-19 大正製薬株式会社 冬虫夏草の判別法
US20030044846A1 (en) * 2001-04-03 2003-03-06 Gary Eldridge Screening of chemical compounds purified from biological sources
CA2373708A1 (en) * 2000-03-09 2001-09-13 Yale University Phytomics: a genomic-based approach to herbal compositions
US20020095260A1 (en) * 2000-11-28 2002-07-18 Surromed, Inc. Methods for efficiently mining broad data sets for biological markers
EP1425695A2 (de) * 2001-08-13 2004-06-09 Beyong Genomics, Inc. Verfahren und system zum profilieren von biologischen systemen
TW573125B (en) * 2001-08-29 2004-01-21 Combinatorx Inc A screening system for identifying drug-drug interactions and methods of use thereof
EP1512970A1 (de) * 2003-09-05 2005-03-09 Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO Verfahren zur Bestimmung der Wirkung einer Zusammensetzung auf das Profil einer Krankheit
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Also Published As

Publication number Publication date
EP1664767B1 (de) 2007-11-14
US20070160990A1 (en) 2007-07-12
EA011959B1 (ru) 2009-06-30
JP4675896B2 (ja) 2011-04-27
ATE378593T1 (de) 2007-11-15
US20070020180A1 (en) 2007-01-25
EP1664770A1 (de) 2006-06-07
DK1664767T3 (da) 2008-03-25
DE602004010154D1 (de) 2007-12-27
JP2007508603A (ja) 2007-04-05
JP2007510132A (ja) 2007-04-19
DE602004010155T2 (de) 2008-09-25
DE602004010154T2 (de) 2008-09-25
WO2005024421A1 (en) 2005-03-17
WO2005024420A1 (en) 2005-03-17
ATE378594T1 (de) 2007-11-15
EP1664770B1 (de) 2007-11-14
DE602004010155D1 (de) 2007-12-27
CN1875273A (zh) 2006-12-06
EP1512970A1 (de) 2005-03-09
EA200600539A1 (ru) 2006-08-25
EP1664767A1 (de) 2006-06-07
CN1875274A (zh) 2006-12-06
ES2297476T3 (es) 2008-05-01
ES2297475T3 (es) 2008-05-01

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