DK1663185T3 - Forebyggelse og behandling af inflammationsinduceret og/eller immun-medieret knogletab - Google Patents
Forebyggelse og behandling af inflammationsinduceret og/eller immun-medieret knogletabInfo
- Publication number
- DK1663185T3 DK1663185T3 DK04765458T DK04765458T DK1663185T3 DK 1663185 T3 DK1663185 T3 DK 1663185T3 DK 04765458 T DK04765458 T DK 04765458T DK 04765458 T DK04765458 T DK 04765458T DK 1663185 T3 DK1663185 T3 DK 1663185T3
- Authority
- DK
- Denmark
- Prior art keywords
- inflammation
- immune
- induced
- prevention
- treatment
- Prior art date
Links
- 206010061218 Inflammation Diseases 0.000 title abstract 2
- 230000004054 inflammatory process Effects 0.000 title abstract 2
- 230000001404 mediated effect Effects 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- 206010065687 Bone loss Diseases 0.000 title 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 210000000845 cartilage Anatomy 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008177 pharmaceutical agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Veneer Processing And Manufacture Of Plywood (AREA)
- Steroid Compounds (AREA)
- Chemical And Physical Treatments For Wood And The Like (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50471703P | 2003-09-22 | 2003-09-22 | |
| PCT/EP2004/010582 WO2005027882A1 (en) | 2003-09-22 | 2004-09-21 | Prevention and treatment of inflammation-induced and/or immune-mediated bone loss |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1663185T3 true DK1663185T3 (da) | 2009-04-06 |
Family
ID=34375537
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04765458T DK1663185T3 (da) | 2003-09-22 | 2004-09-21 | Forebyggelse og behandling af inflammationsinduceret og/eller immun-medieret knogletab |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20100087413A1 (pl) |
| EP (2) | EP2036548A1 (pl) |
| JP (1) | JP2007533625A (pl) |
| AT (1) | ATE416761T1 (pl) |
| AU (1) | AU2004273610B2 (pl) |
| CA (1) | CA2539741A1 (pl) |
| CY (1) | CY1111246T1 (pl) |
| DE (1) | DE602004018338D1 (pl) |
| DK (1) | DK1663185T3 (pl) |
| ES (1) | ES2317029T3 (pl) |
| NZ (1) | NZ546062A (pl) |
| PL (1) | PL1663185T3 (pl) |
| PT (1) | PT1663185E (pl) |
| SI (1) | SI1663185T1 (pl) |
| WO (1) | WO2005027882A1 (pl) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006026619A2 (en) * | 2004-08-30 | 2006-03-09 | Government Of The United States Of America As Represented By The Secretary Department Of Health And Human Services | Inhibition of viruses using rnase h inhibitors |
| JP5140577B2 (ja) | 2005-03-31 | 2013-02-06 | タケダ カリフォルニア インコーポレイテッド | ヒドロキシステロイドデヒドロゲナーゼ阻害剤 |
| DE102005026231A1 (de) * | 2005-06-07 | 2006-12-14 | Origenis Ag | Peptid-Deformylase (PDF) Inhibitoren 3 |
| EP2319517B1 (en) * | 2006-06-01 | 2013-09-11 | Novagali Pharma S.A. | Use of prodrugs for ocular intravitreous administration |
| AU2007271182B2 (en) * | 2006-07-06 | 2012-03-15 | Glaxo Group Limited | Substituted N-phenylmethyl -5-oxo-proline-2-amides as P2X7-receptor antagonists and their methods of use |
| WO2008055945A1 (en) | 2006-11-09 | 2008-05-15 | Probiodrug Ag | 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcer, cancer and other diseases |
| GB0706072D0 (en) * | 2007-03-28 | 2007-05-09 | Sterix Ltd | Compound |
| KR101022809B1 (ko) * | 2008-02-05 | 2011-03-17 | 재단법인서울대학교산학협력재단 | 면역조절에 의한 캔디다알비칸스 기인성 질환의 치료 |
| WO2010035727A1 (ja) * | 2008-09-25 | 2010-04-01 | 塩野義製薬株式会社 | 新規ピロリノン誘導体およびそれを含有する医薬組成物 |
| WO2010088414A2 (en) * | 2009-01-28 | 2010-08-05 | Emory University | Subunit selective nmda receptor potentiators for the treatment of neurological conditions |
| CU24130B1 (es) | 2009-12-22 | 2015-09-29 | Novartis Ag | Isoquinolinonas y quinazolinonas sustituidas |
| US8440693B2 (en) | 2009-12-22 | 2013-05-14 | Novartis Ag | Substituted isoquinolinones and quinazolinones |
| JP2012041291A (ja) * | 2010-08-18 | 2012-03-01 | Institute Of Physical & Chemical Research | 歯周病の治療または予防剤 |
| ITRM20100614A1 (it) * | 2010-11-24 | 2012-05-25 | D M G Italia S R L | Preparazioni farmaceutiche dell acido 18 beta glicirretico e/o di suoi derivati per infiltrazioni intrarticolari per il trattamento delle artropatie infiammatorie |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| PL2782584T3 (pl) | 2011-11-23 | 2021-12-13 | Therapeuticsmd, Inc. | Naturalne skojarzone hormonalne formulacje i terapie zastępcze |
| EP2855483B1 (en) | 2012-05-24 | 2017-10-25 | Novartis AG | Pyrrolopyrrolidinone compounds |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| WO2014115077A1 (en) | 2013-01-22 | 2014-07-31 | Novartis Ag | Substituted purinone compounds |
| WO2014115080A1 (en) | 2013-01-22 | 2014-07-31 | Novartis Ag | Pyrazolo[3,4-d]pyrimidinone compounds as inhibitors of the p53/mdm2 interaction |
| EA029312B1 (ru) | 2013-05-27 | 2018-03-30 | Новартис Аг | Производные имидазопирролидинона и их применение при лечении заболеваний |
| AU2014272695B2 (en) | 2013-05-28 | 2016-10-20 | Novartis Ag | Pyrazolo-pyrrolidin-4-one derivatives as BET inhibitors and their use in the treatment of disease |
| WO2014191911A1 (en) | 2013-05-28 | 2014-12-04 | Novartis Ag | Pyrazolo-pyrrolidin-4-one derivatives and their use in the treatment of disease |
| AU2014351413B2 (en) | 2013-11-21 | 2017-06-01 | Novartis Ag | Pyrrolopyrrolone derivatives and their use as BET inhibitors |
| CN104873521A (zh) * | 2014-02-27 | 2015-09-02 | 天津药物研究院 | 一种11β-羟基类固醇脱氢酶抑制剂、药用组合物及其应用 |
| CN104873520A (zh) * | 2014-02-27 | 2015-09-02 | 天津药物研究院 | 一种11β-羟基类固醇脱氢酶抑制剂、药用组合物及其用途 |
| MX2016014281A (es) | 2014-05-22 | 2017-02-22 | Therapeuticsmd Inc | Formulaciones y terapias de reemplazo de combinación de hormonas naturales. |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| WO2017173044A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd Inc. | Steroid hormone compositions in medium chain oils |
| US9931349B2 (en) | 2016-04-01 | 2018-04-03 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| KR20200074085A (ko) * | 2017-08-04 | 2020-06-24 | 알데릭스, 인코포레이티드 | 고칼륨혈증 치료를 위한 글리시레틴산 유도체 |
| GB201805100D0 (en) * | 2018-03-28 | 2018-05-09 | Benevolentai Bio Ltd | Treatment of sarcopenic diseases |
| SG11202108541RA (en) | 2019-02-07 | 2021-09-29 | Ardelyx Inc | Glycyrrhetinic acid derivatives for use in treating hyperkalemia |
| WO2025026525A1 (de) * | 2023-07-28 | 2025-02-06 | Symrise Ag | Heterozyklische verbindungen als physiologische kühlstoffe |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3262851A (en) * | 1958-06-26 | 1966-07-26 | Biorex Laboratories Ltd | Pharmacological compositions containing glycyrrhetinic acid derivative |
| DE2050072C3 (de) * | 1970-10-12 | 1975-01-30 | Inverni Della Beffa S.P.A., Mailand (Italien) | Aluminium-tri-3-acetyl-18 betaglycyrrthetinat, Verfahren zu seiner Herstellung und dieses enthaltende pharmazeutische Zubereitungen |
| US3934027A (en) * | 1973-05-03 | 1976-01-20 | Pfizer Inc. | 18β-Glycyrrhetinic acid amides useful as antiulcer agents |
| EP0496520A1 (en) * | 1991-01-22 | 1992-07-29 | Merck & Co. Inc. | Novel bone acting agents |
| GB2261672A (en) * | 1991-11-18 | 1993-05-26 | Michael Braden | The use of biomaterials for tissue repair |
| JPH07291857A (ja) * | 1994-04-27 | 1995-11-07 | Suntory Ltd | グリチルレチン酸化合物を有効成分とする骨疾患の予防及び治療剤 |
| DE19951970A1 (de) * | 1999-10-28 | 2001-05-03 | Bionetworks Gmbh | Arzneimittel für die Toleranzinduktion |
| US20050048007A1 (en) * | 2000-11-02 | 2005-03-03 | Inobys Ltd. | Plaque reducing composition |
| GB0105772D0 (en) | 2001-03-08 | 2001-04-25 | Sterix Ltd | Use |
| GB0107383D0 (en) * | 2001-03-23 | 2001-05-16 | Univ Edinburgh | Lipid profile modulation |
| CA2466491A1 (en) | 2001-11-22 | 2003-05-30 | Biovitrum Ab | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 |
| WO2003043999A1 (en) | 2001-11-22 | 2003-05-30 | Biovitrum Ab | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 |
| CA2474168A1 (en) | 2002-02-01 | 2003-08-14 | Merck & Co., Inc. | 11-beta-hydroxysteroid dehydrogenase 1 inhibitors useful for the treatment of diabetes, obesity and dyslipidemia |
| AR040241A1 (es) | 2002-06-10 | 2005-03-23 | Merck & Co Inc | Inhibidores de la 11-beta-hidroxiesteroide deshidrogrenasa 1 para el tratamiento de la diabetes obesidad y dislipidemia |
| EP2380900A1 (en) | 2002-09-23 | 2011-10-26 | E. I. du Pont de Nemours and Company | Isolation and use of ryanodine receptors |
| JO2397B1 (en) | 2002-12-20 | 2007-06-17 | ميرك شارب اند دوم كوربوريشن | Terazol derivatives as beta-hydroxy steroid dihydrogenase-1 inhibitors |
| WO2004056744A1 (en) | 2002-12-23 | 2004-07-08 | Janssen Pharmaceutica N.V. | Adamantyl acetamides as hydroxysteroid dehydrogenase inhibitors |
| US20030148349A1 (en) * | 2003-01-03 | 2003-08-07 | Shyam Ramakrishnan | Regulation of human 11 beta-hydroxysteroid dehydrogenase 1-like enzyme |
| TW200503994A (en) | 2003-01-24 | 2005-02-01 | Novartis Ag | Organic compounds |
-
2004
- 2004-09-21 AT AT04765458T patent/ATE416761T1/de active
- 2004-09-21 AU AU2004273610A patent/AU2004273610B2/en not_active Ceased
- 2004-09-21 ES ES04765458T patent/ES2317029T3/es not_active Expired - Lifetime
- 2004-09-21 PL PL04765458T patent/PL1663185T3/pl unknown
- 2004-09-21 NZ NZ546062A patent/NZ546062A/en unknown
- 2004-09-21 US US10/572,795 patent/US20100087413A1/en not_active Abandoned
- 2004-09-21 PT PT04765458T patent/PT1663185E/pt unknown
- 2004-09-21 SI SI200431023T patent/SI1663185T1/sl unknown
- 2004-09-21 CA CA002539741A patent/CA2539741A1/en not_active Abandoned
- 2004-09-21 DE DE602004018338T patent/DE602004018338D1/de not_active Expired - Lifetime
- 2004-09-21 JP JP2006527336A patent/JP2007533625A/ja active Pending
- 2004-09-21 WO PCT/EP2004/010582 patent/WO2005027882A1/en not_active Ceased
- 2004-09-21 EP EP08169750A patent/EP2036548A1/en not_active Withdrawn
- 2004-09-21 EP EP04765458A patent/EP1663185B1/en not_active Expired - Lifetime
- 2004-09-21 DK DK04765458T patent/DK1663185T3/da active
-
2009
- 2009-03-06 CY CY20091100259T patent/CY1111246T1/el unknown
-
2011
- 2011-05-11 US US13/105,434 patent/US20110275584A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ES2317029T3 (es) | 2009-04-16 |
| AU2004273610A1 (en) | 2005-03-31 |
| AU2004273610B2 (en) | 2010-07-01 |
| PT1663185E (pt) | 2009-02-16 |
| CY1111246T1 (el) | 2015-06-11 |
| EP1663185B1 (en) | 2008-12-10 |
| WO2005027882A1 (en) | 2005-03-31 |
| ATE416761T1 (de) | 2008-12-15 |
| EP1663185A1 (en) | 2006-06-07 |
| CA2539741A1 (en) | 2005-03-31 |
| JP2007533625A (ja) | 2007-11-22 |
| EP2036548A1 (en) | 2009-03-18 |
| US20110275584A1 (en) | 2011-11-10 |
| SI1663185T1 (sl) | 2009-04-30 |
| NZ546062A (en) | 2009-09-25 |
| PL1663185T3 (pl) | 2009-06-30 |
| DE602004018338D1 (de) | 2009-01-22 |
| US20100087413A1 (en) | 2010-04-08 |
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