DK1663185T3 - Forebyggelse og behandling af inflammationsinduceret og/eller immun-medieret knogletab - Google Patents
Forebyggelse og behandling af inflammationsinduceret og/eller immun-medieret knogletabInfo
- Publication number
- DK1663185T3 DK1663185T3 DK04765458T DK04765458T DK1663185T3 DK 1663185 T3 DK1663185 T3 DK 1663185T3 DK 04765458 T DK04765458 T DK 04765458T DK 04765458 T DK04765458 T DK 04765458T DK 1663185 T3 DK1663185 T3 DK 1663185T3
- Authority
- DK
- Denmark
- Prior art keywords
- inflammation
- immune
- induced
- prevention
- treatment
- Prior art date
Links
- 206010061218 Inflammation Diseases 0.000 title abstract 2
- 230000004054 inflammatory process Effects 0.000 title abstract 2
- 230000001404 mediated effect Effects 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- 206010065687 Bone loss Diseases 0.000 title 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 210000000845 cartilage Anatomy 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008177 pharmaceutical agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Veneer Processing And Manufacture Of Plywood (AREA)
- Steroid Compounds (AREA)
- Chemical And Physical Treatments For Wood And The Like (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50471703P | 2003-09-22 | 2003-09-22 | |
| PCT/EP2004/010582 WO2005027882A1 (en) | 2003-09-22 | 2004-09-21 | Prevention and treatment of inflammation-induced and/or immune-mediated bone loss |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1663185T3 true DK1663185T3 (da) | 2009-04-06 |
Family
ID=34375537
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04765458T DK1663185T3 (da) | 2003-09-22 | 2004-09-21 | Forebyggelse og behandling af inflammationsinduceret og/eller immun-medieret knogletab |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20100087413A1 (da) |
| EP (2) | EP1663185B1 (da) |
| JP (1) | JP2007533625A (da) |
| AT (1) | ATE416761T1 (da) |
| AU (1) | AU2004273610B2 (da) |
| CA (1) | CA2539741A1 (da) |
| CY (1) | CY1111246T1 (da) |
| DE (1) | DE602004018338D1 (da) |
| DK (1) | DK1663185T3 (da) |
| ES (1) | ES2317029T3 (da) |
| NZ (1) | NZ546062A (da) |
| PL (1) | PL1663185T3 (da) |
| PT (1) | PT1663185E (da) |
| SI (1) | SI1663185T1 (da) |
| WO (1) | WO2005027882A1 (da) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005279845A1 (en) * | 2004-08-30 | 2006-03-09 | Government Of The United States Of America, As Represented By The Secretary Department Of Health And Human Services | Inhibition of viruses using RNase H inhibitors |
| WO2006105127A2 (en) | 2005-03-31 | 2006-10-05 | Takeda San Diego, Inc. | Hydroxysteroid dehydrogenase inhibitors |
| DE102005026231A1 (de) * | 2005-06-07 | 2006-12-14 | Origenis Ag | Peptid-Deformylase (PDF) Inhibitoren 3 |
| PT1864668E (pt) * | 2006-06-01 | 2013-02-26 | Novagali Pharma Sa | Utilização de pró-fármacos para administração ocular intravítrea |
| EA016076B1 (ru) | 2006-07-06 | 2012-01-30 | Глэксо Груп Лимитед | Замещенные n-фенилметил-5-оксопролин-2-амиды в качестве антагонистов р2х7-рецептора и способы их применения |
| US8278345B2 (en) | 2006-11-09 | 2012-10-02 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
| GB0706072D0 (en) * | 2007-03-28 | 2007-05-09 | Sterix Ltd | Compound |
| KR101022809B1 (ko) * | 2008-02-05 | 2011-03-17 | 재단법인서울대학교산학협력재단 | 면역조절에 의한 캔디다알비칸스 기인성 질환의 치료 |
| TW201016702A (en) * | 2008-09-25 | 2010-05-01 | Shionogi & Co | Novel pyrrolinone derivative and pharmaceutical composition comprising the same |
| WO2010088408A2 (en) * | 2009-01-28 | 2010-08-05 | Emory University | Subunit selective nmda receptor antagonists for the treatment of neurological conditions |
| CU24130B1 (es) | 2009-12-22 | 2015-09-29 | Novartis Ag | Isoquinolinonas y quinazolinonas sustituidas |
| US8440693B2 (en) | 2009-12-22 | 2013-05-14 | Novartis Ag | Substituted isoquinolinones and quinazolinones |
| JP2012041291A (ja) * | 2010-08-18 | 2012-03-01 | Institute Of Physical & Chemical Research | 歯周病の治療または予防剤 |
| ITRM20100614A1 (it) * | 2010-11-24 | 2012-05-25 | D M G Italia S R L | Preparazioni farmaceutiche dell acido 18 beta glicirretico e/o di suoi derivati per infiltrazioni intrarticolari per il trattamento delle artropatie infiammatorie |
| EP2782584B1 (en) | 2011-11-23 | 2021-06-09 | TherapeuticsMD, Inc. | Natural combination hormone replacement formulations and therapies |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| CN104321325B (zh) | 2012-05-24 | 2016-11-16 | 诺华股份有限公司 | 吡咯并吡咯烷酮化合物 |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| EP2948453B1 (en) | 2013-01-22 | 2017-08-02 | Novartis AG | Pyrazolo[3,4-d]pyrimidinone compounds as inhibitors of the p53/mdm2 interaction |
| US9403827B2 (en) | 2013-01-22 | 2016-08-02 | Novartis Ag | Substituted purinone compounds |
| EP3004109A1 (en) | 2013-05-27 | 2016-04-13 | Novartis AG | Imidazopyrrolidinone derivatives and their use in the treatment of disease |
| EA028035B1 (ru) | 2013-05-28 | 2017-09-29 | Новартис Аг | Производные пиразолопирролидин-4-она и их применение при лечении заболевания |
| MX2015016421A (es) | 2013-05-28 | 2016-03-03 | Novartis Ag | Derivados de pirazolo-pirrolidin-4-ona como inhibidores de bet y su uso en el tratamiento de enfermedades. |
| WO2015075665A1 (en) | 2013-11-21 | 2015-05-28 | Novartis Ag | Pyrrolopyrrolone derivatives and their use as bet inhibitors |
| CN104873520A (zh) * | 2014-02-27 | 2015-09-02 | 天津药物研究院 | 一种11β-羟基类固醇脱氢酶抑制剂、药用组合物及其用途 |
| CN104873521A (zh) * | 2014-02-27 | 2015-09-02 | 天津药物研究院 | 一种11β-羟基类固醇脱氢酶抑制剂、药用组合物及其应用 |
| AU2015264003A1 (en) | 2014-05-22 | 2016-11-17 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| WO2017173071A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| WO2019060051A1 (en) * | 2017-08-04 | 2019-03-28 | Ardelyx, Inc. | GLYCYRRHETINIC ACID DERIVATIVES FOR THE TREATMENT OF HYPERKALIEMIA |
| GB201805100D0 (en) * | 2018-03-28 | 2018-05-09 | Benevolentai Bio Ltd | Treatment of sarcopenic diseases |
| TWI861053B (zh) | 2019-02-07 | 2024-11-11 | 美商阿德利克斯公司 | 用於治療高鉀血症之化合物及方法 |
| WO2025026525A1 (de) * | 2023-07-28 | 2025-02-06 | Symrise Ag | Heterozyklische verbindungen als physiologische kühlstoffe |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3262851A (en) * | 1958-06-26 | 1966-07-26 | Biorex Laboratories Ltd | Pharmacological compositions containing glycyrrhetinic acid derivative |
| DE2050072C3 (de) * | 1970-10-12 | 1975-01-30 | Inverni Della Beffa S.P.A., Mailand (Italien) | Aluminium-tri-3-acetyl-18 betaglycyrrthetinat, Verfahren zu seiner Herstellung und dieses enthaltende pharmazeutische Zubereitungen |
| US3934027A (en) * | 1973-05-03 | 1976-01-20 | Pfizer Inc. | 18β-Glycyrrhetinic acid amides useful as antiulcer agents |
| EP0496520A1 (en) * | 1991-01-22 | 1992-07-29 | Merck & Co. Inc. | Novel bone acting agents |
| GB2261672A (en) * | 1991-11-18 | 1993-05-26 | Michael Braden | The use of biomaterials for tissue repair |
| JPH07291857A (ja) * | 1994-04-27 | 1995-11-07 | Suntory Ltd | グリチルレチン酸化合物を有効成分とする骨疾患の予防及び治療剤 |
| DE19951970A1 (de) * | 1999-10-28 | 2001-05-03 | Bionetworks Gmbh | Arzneimittel für die Toleranzinduktion |
| US20050048007A1 (en) * | 2000-11-02 | 2005-03-03 | Inobys Ltd. | Plaque reducing composition |
| GB0105772D0 (en) * | 2001-03-08 | 2001-04-25 | Sterix Ltd | Use |
| GB0107383D0 (en) * | 2001-03-23 | 2001-05-16 | Univ Edinburgh | Lipid profile modulation |
| EP1461327A1 (en) | 2001-11-22 | 2004-09-29 | Biovitrum Ab | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 |
| DE60236541D1 (de) | 2001-11-22 | 2010-07-08 | Biovitrum Ab | Inhibitoren von 11-beta-hydroxysteroiddehydrogenase typ 1 |
| EP1474139B1 (en) | 2002-02-01 | 2007-11-21 | Merck & Co., Inc. | 11-beta-hydroxysteroid dehydrogenase 1 inhibitors useful for the treatment of diabetes, obesity and dyslipidemia |
| AR040241A1 (es) | 2002-06-10 | 2005-03-23 | Merck & Co Inc | Inhibidores de la 11-beta-hidroxiesteroide deshidrogrenasa 1 para el tratamiento de la diabetes obesidad y dislipidemia |
| JP2006516884A (ja) | 2002-09-23 | 2006-07-13 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | リアノジン受容体の単離および使用 |
| JO2397B1 (en) | 2002-12-20 | 2007-06-17 | ميرك شارب اند دوم كوربوريشن | Terazol derivatives as beta-hydroxy steroid dihydrogenase-1 inhibitors |
| WO2004056744A1 (en) | 2002-12-23 | 2004-07-08 | Janssen Pharmaceutica N.V. | Adamantyl acetamides as hydroxysteroid dehydrogenase inhibitors |
| US20030148349A1 (en) * | 2003-01-03 | 2003-08-07 | Shyam Ramakrishnan | Regulation of human 11 beta-hydroxysteroid dehydrogenase 1-like enzyme |
| TW200503994A (en) | 2003-01-24 | 2005-02-01 | Novartis Ag | Organic compounds |
-
2004
- 2004-09-21 DE DE602004018338T patent/DE602004018338D1/de not_active Expired - Lifetime
- 2004-09-21 EP EP04765458A patent/EP1663185B1/en not_active Expired - Lifetime
- 2004-09-21 PT PT04765458T patent/PT1663185E/pt unknown
- 2004-09-21 AT AT04765458T patent/ATE416761T1/de active
- 2004-09-21 DK DK04765458T patent/DK1663185T3/da active
- 2004-09-21 WO PCT/EP2004/010582 patent/WO2005027882A1/en not_active Ceased
- 2004-09-21 NZ NZ546062A patent/NZ546062A/en unknown
- 2004-09-21 ES ES04765458T patent/ES2317029T3/es not_active Expired - Lifetime
- 2004-09-21 JP JP2006527336A patent/JP2007533625A/ja active Pending
- 2004-09-21 CA CA002539741A patent/CA2539741A1/en not_active Abandoned
- 2004-09-21 SI SI200431023T patent/SI1663185T1/sl unknown
- 2004-09-21 EP EP08169750A patent/EP2036548A1/en not_active Withdrawn
- 2004-09-21 PL PL04765458T patent/PL1663185T3/pl unknown
- 2004-09-21 US US10/572,795 patent/US20100087413A1/en not_active Abandoned
- 2004-09-21 AU AU2004273610A patent/AU2004273610B2/en not_active Ceased
-
2009
- 2009-03-06 CY CY20091100259T patent/CY1111246T1/el unknown
-
2011
- 2011-05-11 US US13/105,434 patent/US20110275584A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| SI1663185T1 (sl) | 2009-04-30 |
| CY1111246T1 (el) | 2015-06-11 |
| NZ546062A (en) | 2009-09-25 |
| EP1663185A1 (en) | 2006-06-07 |
| DE602004018338D1 (de) | 2009-01-22 |
| ATE416761T1 (de) | 2008-12-15 |
| EP1663185B1 (en) | 2008-12-10 |
| WO2005027882A1 (en) | 2005-03-31 |
| AU2004273610B2 (en) | 2010-07-01 |
| EP2036548A1 (en) | 2009-03-18 |
| CA2539741A1 (en) | 2005-03-31 |
| PT1663185E (pt) | 2009-02-16 |
| JP2007533625A (ja) | 2007-11-22 |
| AU2004273610A1 (en) | 2005-03-31 |
| US20110275584A1 (en) | 2011-11-10 |
| ES2317029T3 (es) | 2009-04-16 |
| PL1663185T3 (pl) | 2009-06-30 |
| US20100087413A1 (en) | 2010-04-08 |
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