DK1663185T3 - Forebyggelse og behandling af inflammationsinduceret og/eller immun-medieret knogletab - Google Patents
Forebyggelse og behandling af inflammationsinduceret og/eller immun-medieret knogletabInfo
- Publication number
- DK1663185T3 DK1663185T3 DK04765458T DK04765458T DK1663185T3 DK 1663185 T3 DK1663185 T3 DK 1663185T3 DK 04765458 T DK04765458 T DK 04765458T DK 04765458 T DK04765458 T DK 04765458T DK 1663185 T3 DK1663185 T3 DK 1663185T3
- Authority
- DK
- Denmark
- Prior art keywords
- inflammation
- immune
- induced
- prevention
- treatment
- Prior art date
Links
- 206010061218 Inflammation Diseases 0.000 title abstract 2
- 230000004054 inflammatory process Effects 0.000 title abstract 2
- 230000001404 mediated effect Effects 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- 206010065687 Bone loss Diseases 0.000 title 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 210000000845 cartilage Anatomy 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008177 pharmaceutical agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Organic Chemistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Veneer Processing And Manufacture Of Plywood (AREA)
- Steroid Compounds (AREA)
- Chemical And Physical Treatments For Wood And The Like (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50471703P | 2003-09-22 | 2003-09-22 | |
| PCT/EP2004/010582 WO2005027882A1 (en) | 2003-09-22 | 2004-09-21 | Prevention and treatment of inflammation-induced and/or immune-mediated bone loss |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1663185T3 true DK1663185T3 (da) | 2009-04-06 |
Family
ID=34375537
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04765458T DK1663185T3 (da) | 2003-09-22 | 2004-09-21 | Forebyggelse og behandling af inflammationsinduceret og/eller immun-medieret knogletab |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20100087413A1 (da) |
| EP (2) | EP2036548A1 (da) |
| JP (1) | JP2007533625A (da) |
| AT (1) | ATE416761T1 (da) |
| AU (1) | AU2004273610B2 (da) |
| CA (1) | CA2539741A1 (da) |
| CY (1) | CY1111246T1 (da) |
| DE (1) | DE602004018338D1 (da) |
| DK (1) | DK1663185T3 (da) |
| ES (1) | ES2317029T3 (da) |
| NZ (1) | NZ546062A (da) |
| PL (1) | PL1663185T3 (da) |
| PT (1) | PT1663185E (da) |
| SI (1) | SI1663185T1 (da) |
| WO (1) | WO2005027882A1 (da) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1796662A2 (en) * | 2004-08-30 | 2007-06-20 | The Government of the U.S.A., as repr. by the Secretary, Dept. of Health & Human Services, the Nat. Inst. of Health | Inhibition of viruses using rnase h inhibitors |
| US7759339B2 (en) | 2005-03-31 | 2010-07-20 | Takeda San Diego, Inc. | Hydroxysteroid dehydrogenase inhibitors |
| DE102005026231A1 (de) * | 2005-06-07 | 2006-12-14 | Origenis Ag | Peptid-Deformylase (PDF) Inhibitoren 3 |
| PT1864668E (pt) * | 2006-06-01 | 2013-02-26 | Novagali Pharma Sa | Utilização de pró-fármacos para administração ocular intravítrea |
| SI2049478T1 (sl) * | 2006-07-06 | 2012-08-31 | Glaxo Group Ltd | Substituirani N-fenilmetil-5-okso-prolin-2-amidi kot antagonisti receptorja P2X7 in postopki za njihovo uporabo |
| JP5379692B2 (ja) | 2006-11-09 | 2013-12-25 | プロビオドルグ エージー | 潰瘍、癌及び他の疾患の治療のためのグルタミニルシクラーゼの阻害薬としての３−ヒドロキシ−１，５−ジヒドロ−ピロール−２−オン誘導体 |
| GB0706072D0 (en) * | 2007-03-28 | 2007-05-09 | Sterix Ltd | Compound |
| KR101022809B1 (ko) * | 2008-02-05 | 2011-03-17 | 재단법인서울대학교산학협력재단 | 면역조절에 의한 캔디다알비칸스 기인성 질환의 치료 |
| WO2010035727A1 (ja) * | 2008-09-25 | 2010-04-01 | 塩野義製薬株式会社 | 新規ピロリノン誘導体およびそれを含有する医薬組成物 |
| US20110319416A1 (en) * | 2009-01-28 | 2011-12-29 | Emory University | Subunit Selective NMDA Receptor Antagonists For The Treatment Of Neurological Conditions |
| CU24130B1 (es) | 2009-12-22 | 2015-09-29 | Novartis Ag | Isoquinolinonas y quinazolinonas sustituidas |
| US8440693B2 (en) | 2009-12-22 | 2013-05-14 | Novartis Ag | Substituted isoquinolinones and quinazolinones |
| JP2012041291A (ja) * | 2010-08-18 | 2012-03-01 | Institute Of Physical & Chemical Research | 歯周病の治療または予防剤 |
| ITRM20100614A1 (it) * | 2010-11-24 | 2012-05-25 | D M G Italia S R L | Preparazioni farmaceutiche dell acido 18 beta glicirretico e/o di suoi derivati per infiltrazioni intrarticolari per il trattamento delle artropatie infiammatorie |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| BR112014012444B1 (pt) | 2011-11-23 | 2021-12-14 | Therapeuticsmd, Inc | Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher |
| US9365576B2 (en) | 2012-05-24 | 2016-06-14 | Novartis Ag | Pyrrolopyrrolidinone compounds |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| EP2948451B1 (en) | 2013-01-22 | 2017-07-12 | Novartis AG | Substituted purinone compounds |
| US9556180B2 (en) | 2013-01-22 | 2017-01-31 | Novartis Ag | Pyrazolo[3,4-d]pyrimidinone compounds as inhibitors of the P53/MDM2 interaction |
| CN105209467B (zh) | 2013-05-27 | 2018-06-08 | 诺华股份有限公司 | 咪唑并吡咯烷酮衍生物及其在治疗疾病中的用途 |
| PT3004112T (pt) | 2013-05-28 | 2017-12-11 | Novartis Ag | Derivados de pirazolo-pirrolidin-4-ona e sua utilização no tratamento de doença |
| KR20160012195A (ko) | 2013-05-28 | 2016-02-02 | 노파르티스 아게 | Bet 억제제로서의 피라졸로-피롤리딘-4-온 유도체 및 질환의 치료에서의 그의 용도 |
| EA029269B1 (ru) | 2013-11-21 | 2018-02-28 | Новартис Аг | Производные пирролопирролона и их применение для лечения заболеваний |
| CN104873521A (zh) * | 2014-02-27 | 2015-09-02 | 天津药物研究院 | 一种11β-羟基类固醇脱氢酶抑制剂、药用组合物及其应用 |
| CN104873520A (zh) * | 2014-02-27 | 2015-09-02 | 天津药物研究院 | 一种11β-羟基类固醇脱氢酶抑制剂、药用组合物及其用途 |
| RU2016143081A (ru) | 2014-05-22 | 2018-06-26 | Терапьютиксмд, Инк. | Натуральные комбинированные гормонозаместительные составы и терапии |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| KR20180126582A (ko) | 2016-04-01 | 2018-11-27 | 쎄러퓨틱스엠디, 인코퍼레이티드 | 스테로이드 호르몬 약제학적 조성물 |
| WO2017173044A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd Inc. | Steroid hormone compositions in medium chain oils |
| CN118440135A (zh) * | 2017-08-04 | 2024-08-06 | 阿德利克斯股份有限公司 | 用于治疗高钾血症的甘草次酸衍生物 |
| GB201805100D0 (en) * | 2018-03-28 | 2018-05-09 | Benevolentai Bio Ltd | Treatment of sarcopenic diseases |
| CN114008065B (zh) | 2019-02-07 | 2025-03-11 | 阿德利克斯股份有限公司 | 用于治疗高钾血症的甘草次酸衍生物 |
| WO2025026525A1 (de) * | 2023-07-28 | 2025-02-06 | Symrise Ag | Heterozyklische verbindungen als physiologische kühlstoffe |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3262851A (en) * | 1958-06-26 | 1966-07-26 | Biorex Laboratories Ltd | Pharmacological compositions containing glycyrrhetinic acid derivative |
| DE2050072C3 (de) * | 1970-10-12 | 1975-01-30 | Inverni Della Beffa S.P.A., Mailand (Italien) | Aluminium-tri-3-acetyl-18 betaglycyrrthetinat, Verfahren zu seiner Herstellung und dieses enthaltende pharmazeutische Zubereitungen |
| US3934027A (en) * | 1973-05-03 | 1976-01-20 | Pfizer Inc. | 18β-Glycyrrhetinic acid amides useful as antiulcer agents |
| EP0496520A1 (en) * | 1991-01-22 | 1992-07-29 | Merck & Co. Inc. | Novel bone acting agents |
| GB2261672A (en) * | 1991-11-18 | 1993-05-26 | Michael Braden | The use of biomaterials for tissue repair |
| JPH07291857A (ja) * | 1994-04-27 | 1995-11-07 | Suntory Ltd | グリチルレチン酸化合物を有効成分とする骨疾患の予防及び治療剤 |
| DE19951970A1 (de) * | 1999-10-28 | 2001-05-03 | Bionetworks Gmbh | Arzneimittel für die Toleranzinduktion |
| US20050048007A1 (en) * | 2000-11-02 | 2005-03-03 | Inobys Ltd. | Plaque reducing composition |
| GB0105772D0 (en) * | 2001-03-08 | 2001-04-25 | Sterix Ltd | Use |
| GB0107383D0 (en) * | 2001-03-23 | 2001-05-16 | Univ Edinburgh | Lipid profile modulation |
| MXPA04004779A (es) | 2001-11-22 | 2004-07-30 | Biovitrum Ab | Inhibidores de 11-beta-hidroxiesteroide deshidrogenasa de tipo 1. |
| EP1461327A1 (en) | 2001-11-22 | 2004-09-29 | Biovitrum Ab | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 |
| JP4368683B2 (ja) | 2002-02-01 | 2009-11-18 | メルク エンド カムパニー インコーポレーテッド | 糖尿病、肥満症および脂質代謝異常の治療に有用な１１−ベータ−ヒドロキシステロイドデヒドロゲナーゼ１阻害剤 |
| AR040241A1 (es) | 2002-06-10 | 2005-03-23 | Merck & Co Inc | Inhibidores de la 11-beta-hidroxiesteroide deshidrogrenasa 1 para el tratamiento de la diabetes obesidad y dislipidemia |
| US7205147B2 (en) | 2002-09-23 | 2007-04-17 | E.I. Du Pont De Nemours And Company | Nucleic acids encoding ryanodine receptors |
| JO2397B1 (en) | 2002-12-20 | 2007-06-17 | ميرك شارب اند دوم كوربوريشن | Terazol derivatives as beta-hydroxy steroid dihydrogenase-1 inhibitors |
| WO2004056744A1 (en) | 2002-12-23 | 2004-07-08 | Janssen Pharmaceutica N.V. | Adamantyl acetamides as hydroxysteroid dehydrogenase inhibitors |
| US20030148349A1 (en) * | 2003-01-03 | 2003-08-07 | Shyam Ramakrishnan | Regulation of human 11 beta-hydroxysteroid dehydrogenase 1-like enzyme |
| TW200503994A (en) | 2003-01-24 | 2005-02-01 | Novartis Ag | Organic compounds |
-
2004
- 2004-09-21 EP EP08169750A patent/EP2036548A1/en not_active Withdrawn
- 2004-09-21 PL PL04765458T patent/PL1663185T3/pl unknown
- 2004-09-21 CA CA002539741A patent/CA2539741A1/en not_active Abandoned
- 2004-09-21 US US10/572,795 patent/US20100087413A1/en not_active Abandoned
- 2004-09-21 SI SI200431023T patent/SI1663185T1/sl unknown
- 2004-09-21 DK DK04765458T patent/DK1663185T3/da active
- 2004-09-21 PT PT04765458T patent/PT1663185E/pt unknown
- 2004-09-21 WO PCT/EP2004/010582 patent/WO2005027882A1/en not_active Ceased
- 2004-09-21 NZ NZ546062A patent/NZ546062A/en unknown
- 2004-09-21 JP JP2006527336A patent/JP2007533625A/ja active Pending
- 2004-09-21 DE DE602004018338T patent/DE602004018338D1/de not_active Expired - Lifetime
- 2004-09-21 ES ES04765458T patent/ES2317029T3/es not_active Expired - Lifetime
- 2004-09-21 AU AU2004273610A patent/AU2004273610B2/en not_active Ceased
- 2004-09-21 AT AT04765458T patent/ATE416761T1/de active
- 2004-09-21 EP EP04765458A patent/EP1663185B1/en not_active Expired - Lifetime
-
2009
- 2009-03-06 CY CY20091100259T patent/CY1111246T1/el unknown
-
2011
- 2011-05-11 US US13/105,434 patent/US20110275584A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| PT1663185E (pt) | 2009-02-16 |
| NZ546062A (en) | 2009-09-25 |
| SI1663185T1 (sl) | 2009-04-30 |
| EP1663185A1 (en) | 2006-06-07 |
| EP1663185B1 (en) | 2008-12-10 |
| ATE416761T1 (de) | 2008-12-15 |
| AU2004273610A1 (en) | 2005-03-31 |
| EP2036548A1 (en) | 2009-03-18 |
| DE602004018338D1 (de) | 2009-01-22 |
| US20110275584A1 (en) | 2011-11-10 |
| AU2004273610B2 (en) | 2010-07-01 |
| CY1111246T1 (el) | 2015-06-11 |
| JP2007533625A (ja) | 2007-11-22 |
| US20100087413A1 (en) | 2010-04-08 |
| PL1663185T3 (pl) | 2009-06-30 |
| WO2005027882A1 (en) | 2005-03-31 |
| ES2317029T3 (es) | 2009-04-16 |
| CA2539741A1 (en) | 2005-03-31 |
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