DK165887A - Modificeret fibrinolytisk enzym - Google Patents

Modificeret fibrinolytisk enzym

Info

Publication number
DK165887A
DK165887A DK165887A DK165887A DK165887A DK 165887 A DK165887 A DK 165887A DK 165887 A DK165887 A DK 165887A DK 165887 A DK165887 A DK 165887A DK 165887 A DK165887 A DK 165887A
Authority
DK
Denmark
Prior art keywords
enzym
fibrinolytic
modified
modified fibrinolytic
fibrinolytic enzym
Prior art date
Application number
DK165887A
Other languages
Danish (da)
English (en)
Other versions
DK165887D0 (da
Inventor
Michael Joseph Browne
Jeffery Hugh Robinson
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of DK165887D0 publication Critical patent/DK165887D0/da
Publication of DK165887A publication Critical patent/DK165887A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
DK165887A 1986-04-02 1987-04-01 Modificeret fibrinolytisk enzym DK165887A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868608020A GB8608020D0 (en) 1986-04-02 1986-04-02 Compounds

Publications (2)

Publication Number Publication Date
DK165887D0 DK165887D0 (da) 1987-04-01
DK165887A true DK165887A (da) 1987-10-02

Family

ID=10595544

Family Applications (1)

Application Number Title Priority Date Filing Date
DK165887A DK165887A (da) 1986-04-02 1987-04-01 Modificeret fibrinolytisk enzym

Country Status (11)

Country Link
EP (1) EP0241210B1 (pt)
JP (1) JPS62289181A (pt)
AU (1) AU602681B2 (pt)
DE (1) DE3780199T2 (pt)
DK (1) DK165887A (pt)
ES (1) ES2042553T3 (pt)
GB (1) GB8608020D0 (pt)
GR (1) GR3005571T3 (pt)
NZ (1) NZ219828A (pt)
PT (1) PT84590B (pt)
ZA (1) ZA872334B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE880255L (en) * 1987-01-30 1988-07-30 American Home Prod Des-epidermal growth factor activators.
NO882226L (no) * 1987-05-22 1988-11-23 Zymogenetics Inc Fibrinolytiske proteiner.
SE8702562L (sv) * 1987-06-18 1988-12-19 Kabigen Ab Nya fibrinolytiska enzymer
EP0340573A3 (de) * 1988-04-30 1990-05-30 BASF Aktiengesellschaft Neue Proteine, ihre Herstellung und Verwendung
DE3836200A1 (de) * 1988-10-24 1990-04-26 Boehringer Mannheim Gmbh Domaenenduplikations-muteine des gewebsplasminogen-aktivators (t-pa)
DE4123845A1 (de) * 1991-07-18 1993-01-21 Boehringer Mannheim Gmbh Pharmazeutische verpackungseinheit enthaltend plasminogenaktivatoren zur mehrfachbolusgabe
AT409379B (de) * 1999-06-02 2002-07-25 Baxter Ag Medium zur protein- und serumfreien kultivierung von zellen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR79202B (pt) * 1982-05-05 1984-10-22 Genentech Inc
US4753879A (en) * 1984-08-27 1988-06-28 Biogen N.V. Modified tissue plasminogen activators
AU7090787A (en) * 1986-02-19 1987-10-08 Beecham Group Plc Tissue plasminogen activator
PT84588B (en) * 1986-04-02 1989-05-09 Beecham Group Plc Process for preparing a fibrinolytic enzyme
PT84587B (pt) * 1986-04-02 1989-11-30 Beecham Group Plc Processo para preparacao de uma enzima fibrinolitica

Also Published As

Publication number Publication date
DE3780199D1 (de) 1992-08-13
GR3005571T3 (pt) 1993-06-07
EP0241210A1 (en) 1987-10-14
GB8608020D0 (en) 1986-05-08
PT84590A (en) 1987-04-01
PT84590B (pt) 1989-11-30
DK165887D0 (da) 1987-04-01
EP0241210B1 (en) 1992-07-08
AU7090587A (en) 1987-10-08
NZ219828A (en) 1990-08-28
AU602681B2 (en) 1990-10-25
JPS62289181A (ja) 1987-12-16
DE3780199T2 (de) 1993-01-21
ES2042553T3 (es) 1993-12-16
ZA872334B (en) 1987-12-30

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment
PBP Patent lapsed