DK165594C - (-)-benzhydrylsulfinylacetamid, fremgangsmaade til fremstilling heraf, terapeutisk praeparat indeholdende denne forbindelse, samt anvendelse af forbindelsen til fremstilling af et laegemiddel - Google Patents

(-)-benzhydrylsulfinylacetamid, fremgangsmaade til fremstilling heraf, terapeutisk praeparat indeholdende denne forbindelse, samt anvendelse af forbindelsen til fremstilling af et laegemiddel

Info

Publication number
DK165594C
DK165594C DK049687A DK49687A DK165594C DK 165594 C DK165594 C DK 165594C DK 049687 A DK049687 A DK 049687A DK 49687 A DK49687 A DK 49687A DK 165594 C DK165594 C DK 165594C
Authority
DK
Denmark
Prior art keywords
compound
preparation
benzhydrylsulphinylacetamide
medicine
preparing
Prior art date
Application number
DK049687A
Other languages
Danish (da)
English (en)
Other versions
DK165594B (da
DK49687A (da
DK49687D0 (da
Inventor
Louis Lafon
Original Assignee
Lafon Labor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lafon Labor filed Critical Lafon Labor
Publication of DK49687D0 publication Critical patent/DK49687D0/da
Publication of DK49687A publication Critical patent/DK49687A/da
Publication of DK165594B publication Critical patent/DK165594B/da
Application granted granted Critical
Publication of DK165594C publication Critical patent/DK165594C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK049687A 1986-01-31 1987-01-30 (-)-benzhydrylsulfinylacetamid, fremgangsmaade til fremstilling heraf, terapeutisk praeparat indeholdende denne forbindelse, samt anvendelse af forbindelsen til fremstilling af et laegemiddel DK165594C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8601337A FR2593809B1 (fr) 1986-01-31 1986-01-31 Benzhydrylsulfinylacetamide, procede de preparation et utilisation en therapeutique
FR8601337 1986-01-31

Publications (4)

Publication Number Publication Date
DK49687D0 DK49687D0 (da) 1987-01-30
DK49687A DK49687A (da) 1987-08-01
DK165594B DK165594B (da) 1992-12-21
DK165594C true DK165594C (da) 1993-05-03

Family

ID=9331665

Family Applications (1)

Application Number Title Priority Date Filing Date
DK049687A DK165594C (da) 1986-01-31 1987-01-30 (-)-benzhydrylsulfinylacetamid, fremgangsmaade til fremstilling heraf, terapeutisk praeparat indeholdende denne forbindelse, samt anvendelse af forbindelsen til fremstilling af et laegemiddel

Country Status (10)

Country Link
US (1) US4927855A (es)
EP (1) EP0233106B1 (es)
JP (1) JPH06102623B2 (es)
CA (1) CA1274543A (es)
DE (1) DE3760201D1 (es)
DK (1) DK165594C (es)
ES (1) ES2009133B3 (es)
FR (1) FR2593809B1 (es)
GR (1) GR3000128T3 (es)
IE (1) IE59832B1 (es)

Families Citing this family (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2663225B1 (fr) * 1990-06-14 1994-11-04 Lafon Labor Nouvelle utilisation du modafinil.
FR2684875B1 (fr) * 1991-12-13 1995-05-24 Lafon Labor Utilisation du modafinil pour la fabrication d'un medicament ayant un effet anti-ischemique.
FR2697162B1 (fr) * 1992-10-23 1995-01-13 Lafon Labor Utilisation du modafinil pour la fabrication d'un médicament pour le traitement de l'incontinence urinaire et des troubles sphinctériens urétro vésicaux.
FR2708201B1 (fr) * 1993-06-30 1995-10-20 Lafon Labor Utilisation de dérivés d'acétamide pour la fabrication de médicaments.
US5618845A (en) 1994-10-06 1997-04-08 Cephalon, Inc. Acetamide derivative having defined particle size
US6346548B1 (en) * 1999-08-16 2002-02-12 Cephalon, Inc. Compositions including modafinil for treatment of attention deficit hyperactivity disorder and multiple sclerosis fatigue
US6455588B1 (en) 1999-08-20 2002-09-24 Cephalon, Inc. Compositions including modafinil for treatment of eating disorders and for appetite stimulation
FR2804322B1 (fr) * 2000-01-31 2002-04-19 Lafon Labor Utilisation du modafinil pour la fabrication d'un medicament destine a corriger les troubles de la vigilance associes aux myopathies
US6492396B2 (en) 2000-05-16 2002-12-10 Cephalon, Inc. Substituted thioacetamides
US6670358B2 (en) * 2000-05-16 2003-12-30 Cephalon, Inc. Substituted thioacetamides
CN100500651C (zh) * 2000-07-27 2009-06-17 特瓦制药工业有限公司 晶体和纯莫达非尼及其制备方法
CN100584322C (zh) * 2000-10-11 2010-01-27 赛福伦公司 包含莫达非尼化合物的组合物
US6919378B2 (en) * 2000-10-11 2005-07-19 Cephalon, Inc. Pharmaceutical solutions of modafinil compounds
US6489363B2 (en) 2000-10-11 2002-12-03 Cephalon, Inc. Pharmaceutical solutions of modafinil compounds
US7141555B2 (en) 2000-12-19 2006-11-28 Cephalon, Inc. Modafinil compound and cyclodextrin mixtures
US7704975B2 (en) * 2000-12-19 2010-04-27 Cephalon, Inc. Modafinil compound and cyclodextrin mixtures
US20080058424A1 (en) * 2002-05-23 2008-03-06 Cephalon, Inc. Novel pharmaceutical formulations of modafinil
KR100911779B1 (ko) * 2001-05-25 2009-08-12 세파론, 인코포레이티드 모다피닐을 포함하는 고형 제약 제제
US20100311701A1 (en) * 2002-02-15 2010-12-09 Transform Pharmaceuticals, Inc Pharmaceutical Co-Crystal Compositions
US7790905B2 (en) * 2002-02-15 2010-09-07 Mcneil-Ppc, Inc. Pharmaceutical propylene glycol solvate compositions
US7927613B2 (en) * 2002-02-15 2011-04-19 University Of South Florida Pharmaceutical co-crystal compositions
CA2477923C (en) * 2002-03-01 2021-02-23 University Of South Florida Multiple-component solid phases containing at least one active pharmaceutical ingredient
ITMI20020991A1 (it) * 2002-05-10 2003-11-10 Dinamite Dipharma S P A In For Procedimento per la sintesi del modafinil
US6875893B2 (en) * 2002-05-23 2005-04-05 Cephalon, Inc. Preparations of a sulfinyl acetamide
US7229644B2 (en) * 2002-05-23 2007-06-12 Cephalon, Inc. Pharmaceutical formulations of modafinil
CA2489984A1 (en) * 2002-06-21 2003-12-31 Transform Pharmaceuticals, Inc. Pharmaceutical compositions with improved dissolution
US20040048931A1 (en) * 2002-07-12 2004-03-11 Craig Heacock Modafinil pharmaceutical compositions
US6992219B2 (en) * 2002-08-09 2006-01-31 Cephalon France Modafinil polymorphic forms
US20040116532A1 (en) * 2002-09-13 2004-06-17 Craig Heacock Pharmaceutical formulations of modafinil
US20040138180A1 (en) * 2002-10-03 2004-07-15 Barr Laboratories, Inc. Bisphosphonate composition and process for the preparation thereof
IL153098A0 (en) * 2002-11-26 2003-06-24 Chemagis Ltd Pharmaceutical compositions containing modafinil
FR2849029B1 (fr) 2002-12-20 2005-03-18 Lafon Labor Procede de preparation et formes cristallines des enantiomeres optiques du modafinil.
US8183290B2 (en) 2002-12-30 2012-05-22 Mcneil-Ppc, Inc. Pharmaceutically acceptable propylene glycol solvate of naproxen
WO2004075827A2 (en) * 2003-01-31 2004-09-10 Alembic Limited Process for the preparation of 2-[(diphenylmethyl) thio] acetamide
CA2511992A1 (en) 2003-02-24 2004-09-10 Mallinckrodt Inc. Process for preparing benzhydrylthioacetamide
WO2004082630A2 (en) * 2003-03-17 2004-09-30 Neurohealing Pharmaceuticals, Inc. High potency dopaminergic treatment of neurological impairment associated with brain injury
US20040253308A1 (en) * 2003-04-29 2004-12-16 Barr Laboratories, Inc. Surface-treated modafinil particles
US20040229941A1 (en) * 2003-05-13 2004-11-18 Cephalon, Inc. Analeptic and antidepressant combinations
AR045423A1 (es) * 2003-05-13 2005-10-26 Cephalon Inc Combinaciones de analiticos y antidepresivos
AR045314A1 (es) * 2003-05-13 2005-10-26 Cephalon Inc Composiciones farmaceuticas de analepticos y antidepresivos
US20040242698A1 (en) * 2003-05-13 2004-12-02 Cephalon Inc. Analeptic and antidepressant combinations
ATE442352T1 (de) * 2003-05-16 2009-09-15 Cephalon France Verfahren zur herstellung von modafinil
ITMI20031298A1 (it) * 2003-06-26 2004-12-27 Erregierre Spa Processo di preparazione di modafinil forma polimorfa(i).
MXPA06002507A (es) * 2003-09-04 2006-06-20 Cephalon Inc Composiciones de modafinil.
US7566805B2 (en) * 2003-09-04 2009-07-28 Cephalon, Inc. Modafinil compositions
EP1670753A4 (en) * 2003-09-04 2008-01-02 Cephalon Inc MODAFINIL COMPOSITIONS
WO2005046854A2 (en) * 2003-09-12 2005-05-26 Sun Pharmaceutical Industries Limited A process for the preparation of diphenylmethylsulfinyl derivatives
EP1516869A1 (en) * 2003-09-19 2005-03-23 Cephalon France Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation
US7368591B2 (en) 2003-09-19 2008-05-06 Cephalon France Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation
US20050137264A1 (en) * 2003-12-22 2005-06-23 Patel Ashish A. Modafinil compositions
EP2292213A1 (en) * 2004-02-06 2011-03-09 Cephalon, Inc. Compositions comprising a polymorphic form of armodafinil
CN1980888B (zh) * 2004-02-06 2011-04-13 赛福伦公司 莫达芬尼组合物
US20090018202A1 (en) 2004-02-06 2009-01-15 Cephalon, Inc. Modafinil compositions
JP4917441B2 (ja) * 2004-02-06 2012-04-18 セフアロン・インコーポレーテツド モダフィニル組成物
WO2005099822A2 (en) * 2004-04-13 2005-10-27 Cephalon, Inc. Reduction of drug / drug interactions with modafinil
US7449481B2 (en) * 2004-04-13 2008-11-11 Cephalon, Inc. Thio-substituted biaryl-methanesulfinyl derivatives
US7297817B2 (en) * 2004-04-13 2007-11-20 Cephalon France Thio-substituted arylmethanesulfinyl derivatives
US7314875B2 (en) * 2004-04-13 2008-01-01 Cephalon, Inc. Tricyclic aromatic and bis-phenyl sulfinyl derivatives
EP1586560A1 (en) * 2004-04-13 2005-10-19 Cephalon, Inc. Thio-substituted arylmethanesulfinyl derivatives
US7119214B2 (en) * 2004-04-13 2006-10-10 Cephalon France Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives
US20060024370A1 (en) * 2004-07-29 2006-02-02 Cephalon France Modafinil oral lyophilizate
US20060086667A1 (en) * 2004-09-13 2006-04-27 Cephalon, Inc., U.S. Corporation Methods for the separation of enantiomeric sulfinylacetamides
EP1634861A1 (en) * 2004-09-13 2006-03-15 Cephalon, Inc. Methods for the separation of modafinil
EP1702915A1 (en) * 2005-03-14 2006-09-20 Cephalon France Process for enantioselective synthesis of single enantiomers of thio-substituted arylmethanesulfinyl derivatives by asymmetric oxidation
US20090123545A1 (en) * 2005-07-21 2009-05-14 Ron Eyal S Rapid Onset and Short Term Modafinil Compositions and Methods of Use Thereof
KR101146807B1 (ko) * 2005-07-29 2012-05-21 반다 파마슈티칼즈, 인코퍼레이티드. 각성을 향상시키는 방법
ITMI20051971A1 (it) * 2005-10-18 2007-04-19 Dipharma Spa Procedimento per la preparazione di - modafinil
EP1973873A2 (en) * 2005-12-09 2008-10-01 Mallinckrodt Inc. Processes for the preparation of modafinil and analogs thereof
US20070293702A1 (en) * 2006-02-21 2007-12-20 Viviana Braude Novel crystalline forms of armodafinil and preparation thereof
EP1954652A2 (en) * 2006-03-01 2008-08-13 Teva Pharmaceutical Industries Ltd An improved process for the preparation of armodafinil
EP2043623A4 (en) * 2006-07-12 2013-03-20 Elan Pharma Int Ltd NANOPARTICLE FORMULATIONS OF MODAFINIL
EP2056811B8 (en) * 2006-08-14 2018-03-21 Neurohealing Pharmaceuticals, Inc. Modafinil-based treatment for premature ejaculation
US20080181966A1 (en) * 2006-10-18 2008-07-31 Cephalon, Inc. Modafinil pharmaceutical compositions
WO2008070143A1 (en) * 2006-12-06 2008-06-12 Teva Pharmaceutical Industries Ltd. Processes for preparing armodafinil intermediate
CN101641090B (zh) * 2006-12-19 2012-12-05 亚勒斯有限公司 莫达非尼在制备治疗多动腿综合征的药物中的应用
US9289403B2 (en) * 2007-03-09 2016-03-22 The Board of Trustees of the University of Arizona Use of modafinil to treat spasticity
WO2008149141A2 (en) * 2007-06-04 2008-12-11 Generics [Uk] Limited Novel process
US7960586B2 (en) * 2007-08-16 2011-06-14 Teva Pharmaceutical Industries Ltd. Purification of armodafinil
US20090082462A1 (en) * 2007-09-25 2009-03-26 Protia, Llc Deuterium-enriched armodafinil
EP1911739A3 (en) 2007-11-05 2008-09-17 Dipharma Francis S.r.l. Crystalline form of (S)-2-phenylethylammonium (R)-diphenyl-methanesulphinyl-acetate
US20090325999A1 (en) * 2008-06-27 2009-12-31 Jie Du Personalized pharmaceutical kits, packaging and compositions for the treatment of allergic conditions
US20100036164A1 (en) * 2008-08-06 2010-02-11 Srinivas Areveli Preparation of armodafinil form i
EP2238973A1 (en) 2009-04-07 2010-10-13 Cephalon France Lyophilized preparations of proteasome inhibitors
EP2649187B1 (en) 2010-12-08 2017-11-22 Codexis, Inc. Biocatalysts and methods for the synthesis of armodafinil
FR2970711B1 (fr) * 2011-01-20 2016-03-04 Hopitaux Paris Assist Publique La lauflumide et ses enantiomeres, preparation et utilisations therapeutiques
CN103058900B (zh) * 2012-12-14 2014-11-26 重庆康乐制药有限公司 一种r-二苯甲基亚硫酰乙酸的制备方法
US9862679B2 (en) 2013-03-08 2018-01-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Office Of Technology Transfer, National Institutes Of Health Potent and selective inhibitors of monoamine transporters; method of making; and use thereof
CN104341327A (zh) * 2013-08-08 2015-02-11 中国人民解放军63975部队 多卤素取代2-(二苯甲基亚硫酰基)乙酰胺类化合物及其立体异构体
US9616068B2 (en) 2014-10-27 2017-04-11 Pohela LLC Animal training using cognitive enhancement
US11365195B2 (en) 2017-11-13 2022-06-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Atypical inhibitors of monoamine transporters; method of making; and use thereof
KR102126389B1 (ko) 2018-09-14 2020-06-25 셀라이온바이오메드 주식회사 벤즈히드릴티오 아세트아미드 화합물을 유효성분으로 포함하는 간 질환의 예방 또는 치료용 조성물
KR102277739B1 (ko) 2019-12-11 2021-07-15 셀라이온바이오메드 주식회사 벤즈히드릴 티오 아세트아미드 화합물을 유효성분으로 포함하는 섬유화 질환의 치료용 조성물
WO2022007578A1 (zh) * 2020-07-10 2022-01-13 广州新创忆药物临床研究有限公司 治疗阿尔茨海默病的组合及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1584462A (en) * 1977-03-31 1981-02-11 Lafon Labor N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them
FR2528038B2 (fr) * 1982-06-04 1985-08-09 Lafon Labor Derives de benzhydrylsulfinylacetamide et leur utilisation en therapeutique

Also Published As

Publication number Publication date
ES2009133B3 (es) 1989-09-01
JPH06102623B2 (ja) 1994-12-14
DK165594B (da) 1992-12-21
DE3760201D1 (en) 1989-07-06
DK49687A (da) 1987-08-01
EP0233106B1 (fr) 1989-05-31
IE870240L (en) 1987-07-31
CA1274543A (fr) 1990-09-25
DK49687D0 (da) 1987-01-30
IE59832B1 (en) 1994-04-06
JPS62190160A (ja) 1987-08-20
GR3000128T3 (en) 1990-11-29
FR2593809A1 (fr) 1987-08-07
US4927855A (en) 1990-05-22
FR2593809B1 (fr) 1988-07-22
EP0233106A1 (fr) 1987-08-19

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