DK165412C - Fremgangsmaade til fremstilling af humant interleukin - Google Patents

Fremgangsmaade til fremstilling af humant interleukin

Info

Publication number
DK165412C
DK165412C DK421383A DK421383A DK165412C DK 165412 C DK165412 C DK 165412C DK 421383 A DK421383 A DK 421383A DK 421383 A DK421383 A DK 421383A DK 165412 C DK165412 C DK 165412C
Authority
DK
Denmark
Prior art keywords
interleukin
humant
manufacturing
purified
lymphocytes
Prior art date
Application number
DK421383A
Other languages
Danish (da)
English (en)
Other versions
DK421383A (da
DK421383D0 (da
DK165412B (da
Inventor
Alvin S Stern
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK421383D0 publication Critical patent/DK421383D0/da
Publication of DK421383A publication Critical patent/DK421383A/da
Publication of DK165412B publication Critical patent/DK165412B/da
Application granted granted Critical
Publication of DK165412C publication Critical patent/DK165412C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/55—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/948—Microorganisms using viruses or cell lines
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/828—Cancer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/141—Interleukin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK421383A 1982-09-16 1983-09-15 Fremgangsmaade til fremstilling af humant interleukin DK165412C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/418,927 US4490289A (en) 1982-09-16 1982-09-16 Homogeneous human interleukin 2
US41892782 1982-09-16

Publications (4)

Publication Number Publication Date
DK421383D0 DK421383D0 (da) 1983-09-15
DK421383A DK421383A (da) 1984-03-17
DK165412B DK165412B (da) 1992-11-23
DK165412C true DK165412C (da) 1993-04-13

Family

ID=23660116

Family Applications (1)

Application Number Title Priority Date Filing Date
DK421383A DK165412C (da) 1982-09-16 1983-09-15 Fremgangsmaade til fremstilling af humant interleukin

Country Status (14)

Country Link
US (2) US4490289A (OSRAM)
EP (1) EP0106179B1 (OSRAM)
JP (1) JPS5970620A (OSRAM)
AT (1) ATE20073T1 (OSRAM)
AU (1) AU598251B2 (OSRAM)
CA (1) CA1239871A (OSRAM)
CS (1) CS395391A3 (OSRAM)
DE (1) DE3363781D1 (OSRAM)
DK (1) DK165412C (OSRAM)
IE (1) IE55920B1 (OSRAM)
IL (1) IL69731A (OSRAM)
NZ (1) NZ205593A (OSRAM)
PH (1) PH17834A (OSRAM)
ZA (1) ZA836830B (OSRAM)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3377363D1 (en) * 1982-03-31 1988-08-18 Ajinomoto Kk Gene coding for interleukin-2 polypeptide, recombinant dna carrying said gene, cell lines possessing the recombinant dna,and method for producing interleukin-2 using said cells
US4778879A (en) * 1982-04-20 1988-10-18 Sloan-Kettering Institute For Cancer Research Highly purified human interleukin 2 and method
US4925919A (en) * 1984-04-25 1990-05-15 Roland Mertelsmann Purified interleukin 2
US4950598A (en) * 1982-09-22 1990-08-21 The Board Of Trustees Of The Leland Stanford Junior University Process for making T cell hybridomas
US4992271A (en) * 1982-09-23 1991-02-12 Cetus Corporation Formulation for lipophilic IL-2 proteins
US4853332A (en) * 1982-10-19 1989-08-01 Cetus Corporation Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of biologically active proteins
US5700913A (en) * 1982-12-15 1997-12-23 Ajinomoto Co., Inc. Unglycosylated human interleukin-2 polypeptides
US4518584A (en) * 1983-04-15 1985-05-21 Cetus Corporation Human recombinant interleukin-2 muteins
US4723000A (en) * 1983-07-05 1988-02-02 Biospectrum, Inc. Human interferon gamma and interleukin-2
WO1985000606A1 (fr) * 1983-07-19 1985-02-14 Takeda Chemical Industries, Ltd. Il-2 humaine et son procede de preparation
US4675383A (en) * 1983-11-15 1987-06-23 The Salk Institute For Biological Studies Purification of T-cell growth factor
JPS60115528A (ja) * 1983-11-28 1985-06-22 Takeda Chem Ind Ltd ヒトインタ―ロイキン―２蛋白質を含有する抗腫瘍用または免疫機能低下疾患治療用組成物
US4604377A (en) * 1984-03-28 1986-08-05 Cetus Corporation Pharmaceutical compositions of microbially produced interleukin-2
US4569790A (en) * 1984-03-28 1986-02-11 Cetus Corporation Process for recovering microbially produced interleukin-2 and purified recombinant interleukin-2 compositions
EP0158487B1 (en) * 1984-04-09 1991-08-28 Takeda Chemical Industries, Ltd. Stable composition of interleukin-2
US4908433A (en) * 1984-04-25 1990-03-13 Sloan-Kettering Institute For Cancer Research Uses of interleukin-2
US4908434A (en) * 1984-04-25 1990-03-13 Sloan-Kettering Institute For Cancer Research Process for preparing purified interleukin-2
US4696915A (en) * 1984-05-25 1987-09-29 Hoffmann-La Roche Inc. Parathymosin alpha
US4572798A (en) * 1984-12-06 1986-02-25 Cetus Corporation Method for promoting disulfide bond formation in recombinant proteins
US4921667A (en) * 1985-04-23 1990-05-01 New York University Method for augmenting immune response
US4690893A (en) * 1985-05-03 1987-09-01 Dnax Research Institute Of Molecular And Cellular Biology, Inc. Hybridoma cell lines producing monoclonal antibodies which specifically bind to mouse interleukin-2
CA1297003C (en) * 1985-09-20 1992-03-10 Jack H. Nunberg Composition and method for treating animals
US4933433A (en) * 1986-01-31 1990-06-12 E. I. Du Pont De Nemours And Company Recombinant interleukin-2 composition and process for making it
US4770781A (en) * 1986-03-03 1988-09-13 Merck & Co., Inc. Purification of human interleukin-1 species
ATE82588T1 (de) * 1986-04-28 1992-12-15 Endotronics Inc Zuchtverfahren fuer leukocyten.
US4832686A (en) * 1986-06-24 1989-05-23 Anderson Mark E Method for administering interleukin-2
DE3621828A1 (de) * 1986-06-28 1988-01-14 Biotest Pharma Gmbh Stabilisierung eines fuer therapeutische zwecke, insbesondere beim menschen, bestimmten interleukin-2-praeparates sowie dieses praeparat enthaltende stabilisierte waessrige loesung oder feststoff
US4931543A (en) * 1987-05-11 1990-06-05 Cetus Corporation Process for recovering microbially produced interleukin-2
US5034513A (en) * 1987-05-27 1991-07-23 The United States Of America As Represented By The Secretary Of Agriculture Avian interleukin-2
US5417970A (en) * 1988-10-21 1995-05-23 Sanofi Drugs containing a glycosylated interleukin-2
JPH0266086U (OSRAM) * 1988-11-07 1990-05-18
US5245016A (en) * 1991-01-31 1993-09-14 University Of Utah Research Foundation Pseudomonas maltophilia immunoglobulin binding protein and methods for its use
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
JP4128625B2 (ja) 1995-10-17 2008-07-30 ウェイン ステイト ユニヴァーシティ チキンインターロイキン−１５及びその使用
CA2278847A1 (en) * 1997-01-31 1998-08-06 Hemosol Inc. Method for the production of selected lymphocytes
WO2001079444A2 (en) 2000-04-12 2001-10-25 Human Genome Sciences, Inc Albumin fusion proteins
EP2277888A3 (en) 2001-12-21 2011-04-27 Human Genome Sciences, Inc. Fusion proteins of albumin and erythropoietin
US20050282814A1 (en) * 2002-10-03 2005-12-22 Targegen, Inc. Vasculostatic agents and methods of use thereof
WO2004030635A2 (en) * 2002-10-03 2004-04-15 Targegen, Inc. Vasculostatic agents and methods of use thereof
EP1594530A4 (en) 2003-01-22 2006-10-11 Human Genome Sciences Inc HYBRID PROTEINS OF ALBUMIN
EP1809614B1 (en) 2004-04-08 2014-05-07 TargeGen, Inc. Benzotriazine inhibitors of kinases
PL382308A1 (pl) 2004-08-25 2007-08-20 Targegen, Inc. Związki heterocykliczne i sposoby stosowania
US20060292203A1 (en) * 2005-06-08 2006-12-28 Targegen, Inc. Methods and compositions for the treatment of ocular disorders
MX391408B (es) * 2005-11-01 2025-03-21 Impact Biomedicines Inc Inhibidores de biaril meta-pirimidina de cinasas.
US8604042B2 (en) * 2005-11-01 2013-12-10 Targegen, Inc. Bi-aryl meta-pyrimidine inhibitors of kinases
US8133900B2 (en) * 2005-11-01 2012-03-13 Targegen, Inc. Use of bi-aryl meta-pyrimidine inhibitors of kinases
WO2007127366A2 (en) * 2006-04-25 2007-11-08 Targegen, Inc. Kinase inhibitors and methods of use thereof
WO2009152610A1 (en) * 2008-06-20 2009-12-23 The Royal Institution For The Advancement Of Learning/Mcgill University Interleukin-2/soluble tgf-beta type ii receptor b conjugates and methods and uses thereof
CA2816957A1 (en) 2010-11-07 2012-05-10 Targegen, Inc. Compositions and methods for treating myelofibrosis
US9332999B2 (en) 2012-08-13 2016-05-10 Covidien Lp Apparatus and methods for clot disruption and evacuation
US9332998B2 (en) 2012-08-13 2016-05-10 Covidien Lp Apparatus and methods for clot disruption and evacuation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4390623A (en) * 1980-10-02 1983-06-28 Hooper Trading Company Serum-free and mitogen-free T-cell growth factor and process for making same
JPS58159420A (ja) * 1982-03-18 1983-09-21 Ajinomoto Co Inc インタ−ロイキン２の精製法
US4925919A (en) * 1984-04-25 1990-05-15 Roland Mertelsmann Purified interleukin 2
US4778879A (en) * 1982-04-20 1988-10-18 Sloan-Kettering Institute For Cancer Research Highly purified human interleukin 2 and method
EP0092163B1 (en) * 1982-04-20 1988-09-28 Sloan-Kettering Institute For Cancer Research Purification of interleukin 2

Also Published As

Publication number Publication date
US5597901A (en) 1997-01-28
US4490289A (en) 1984-12-25
IL69731A0 (en) 1983-12-30
CA1239871A (en) 1988-08-02
JPH0244480B2 (OSRAM) 1990-10-04
EP0106179A1 (de) 1984-04-25
DK421383A (da) 1984-03-17
DE3363781D1 (en) 1986-07-03
IL69731A (en) 1988-01-31
AU1916083A (en) 1984-03-22
AU559677B2 (en) 1987-03-19
PH17834A (en) 1985-01-07
AU7197087A (en) 1987-08-13
IE55920B1 (en) 1991-02-27
DK421383D0 (da) 1983-09-15
AU598251B2 (en) 1990-06-21
IE832168L (en) 1984-03-16
DK165412B (da) 1992-11-23
CS395391A3 (en) 1992-09-16
EP0106179B1 (de) 1986-05-28
JPS5970620A (ja) 1984-04-21
NZ205593A (en) 1987-03-06
ZA836830B (en) 1984-05-30
ATE20073T1 (de) 1986-06-15

Similar Documents

Publication Publication Date Title
DK165412C (da) Fremgangsmaade til fremstilling af humant interleukin
DK0504177T3 (da) IL-11, et pattedyrcytokin
IT1143955B (it) Procedimento di preparazione di un idrolisato di proteine purificato
DK612484A (da) Fremgangsmaade til fremstilling af interleukin-2
IT1150681B (it) Procedimento di micro-incapsulamento,particolarmente di colture di cellule
MX9702666A (es) Nuevos peptidos con efectos inmunoreguladores.
HK40384A (en) Homogeneous fibroblast interferon and method for manufacture thereof
IT8567141A0 (it) Procedimento per la coltura di cellule mediante dispersione di gas
DK623188D0 (da) Fremgangsmaade til inkubation af rekombinante proteinekspressionsceller
DK141188A (da) Fremgangsmaade til direkthydrogenering af smoerfedt
NO169762C (no) Fremgangsmaate til understoettelse av en isbrytingsprosess
DK200387A (da) Fremgangsmaade til vedhaeftning af biologiske stoffer til faste substrater
IT1146998B (it) Esteri di alcoli eterociclici procedimento di produzione e composizioni disinfestanti che le contengono
ES2052562T3 (es) Peptido antineoplasico inducido por la interleucina-2.
SU668929A1 (ru) Паста дл металлизации керамики
IT1147722B (it) Procedimento per la produzione di codeina da culture di cellule
DK489086A (da) Tetradecapeptider med mitogen aktivitet og fremgangsmaade til stimulering af vaeksten af macrophag-lignende celler
IT206001Z2 (it) Piastrina per composizioni varie in particolare di lampade e lampadari
ATE49164T1 (de) Tisch zum fixieren am ruecken eines sessels.
IT1148163B (it) Diagnostica con immonoflurescenza od immunoperossidasi su cellule di coltura infettate in vitro
IT1233453B (it) Produzione di vincamina e di epivincamina mediante colture di cellule di vinca minor.
BR6401118U (pt) Quadro com elementos moveis
IT8248122A0 (it) Procedimento per immobilizzare cellule di microbi con attivita' di glucosio-isomerasi

Legal Events

Date Code Title Description
PUP Patent expired