DK164942C - Fremgangsmaade til bestemmelse af en sekvens af monomerer, der er aekvivalent med en epitop paa et antigen - Google Patents

Fremgangsmaade til bestemmelse af en sekvens af monomerer, der er aekvivalent med en epitop paa et antigen

Info

Publication number
DK164942C
DK164942C DK136086A DK136086A DK164942C DK 164942 C DK164942 C DK 164942C DK 136086 A DK136086 A DK 136086A DK 136086 A DK136086 A DK 136086A DK 164942 C DK164942 C DK 164942C
Authority
DK
Denmark
Prior art keywords
monomers
catamer
preparations
sequence
determining
Prior art date
Application number
DK136086A
Other languages
Danish (da)
English (en)
Other versions
DK136086A (da
DK164942B (da
DK136086D0 (da
Inventor
Hendrik Mario Geysen
Original Assignee
Coselco Mimotopes Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3770684&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK164942(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Coselco Mimotopes Pty Ltd filed Critical Coselco Mimotopes Pty Ltd
Publication of DK136086A publication Critical patent/DK136086A/da
Publication of DK136086D0 publication Critical patent/DK136086D0/da
Publication of DK164942B publication Critical patent/DK164942B/da
Application granted granted Critical
Publication of DK164942C publication Critical patent/DK164942C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in eptitope analysis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806—Antigenic peptides or proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/815—Carrier is a synthetic polymer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/826—Viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Lubricants (AREA)
  • Saccharide Compounds (AREA)
  • Detergent Compositions (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Testing Of Optical Devices Or Fibers (AREA)
  • Cosmetics (AREA)
  • Exchange Systems With Centralized Control (AREA)
  • Control Of Eletrric Generators (AREA)
DK136086A 1984-07-24 1986-03-24 Fremgangsmaade til bestemmelse af en sekvens af monomerer, der er aekvivalent med en epitop paa et antigen DK164942C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AUPG618884 1984-07-24
AUPG618884 1984-07-24
PCT/AU1985/000165 WO1986000991A1 (en) 1984-07-24 1985-07-23 Method for determining mimotopes
AU8500165 1985-07-23

Publications (4)

Publication Number Publication Date
DK136086A DK136086A (da) 1986-03-24
DK136086D0 DK136086D0 (da) 1986-03-24
DK164942B DK164942B (da) 1992-09-14
DK164942C true DK164942C (da) 1993-02-01

Family

ID=3770684

Family Applications (1)

Application Number Title Priority Date Filing Date
DK136086A DK164942C (da) 1984-07-24 1986-03-24 Fremgangsmaade til bestemmelse af en sekvens af monomerer, der er aekvivalent med en epitop paa et antigen

Country Status (10)

Country Link
US (2) US5194392A (no)
EP (1) EP0190205B1 (no)
JP (3) JPH07119760B2 (no)
AT (1) ATE81722T1 (no)
CA (1) CA1255586A (no)
DE (1) DE3586772T2 (no)
DK (1) DK164942C (no)
MY (1) MY102885A (no)
NO (1) NO166465C (no)
WO (1) WO1986000991A1 (no)

Families Citing this family (141)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ215865A (en) * 1985-04-22 1988-10-28 Commw Serum Lab Commission Method of determining the active site of a receptor-binding analogue
IL79881A (en) * 1985-08-28 1995-12-08 Pieczenik George Populations of random coding series of oligonucleotides and peptides
US5866363A (en) * 1985-08-28 1999-02-02 Pieczenik; George Method and means for sorting and identifying biological information
US5041381A (en) 1986-07-03 1991-08-20 Schering Corporation Monoclonal antibodies against human interleukin-4 and hybridomas producing the same
US6222020B1 (en) * 1987-01-07 2001-04-24 Imperial Cancer Research Technology Limited Antigens derived from the core protein of the human mammary epithelial mucin
US5300425A (en) * 1987-10-13 1994-04-05 Terrapin Technologies, Inc. Method to produce immunodiagnostic reagents
ATE152244T1 (de) * 1987-10-13 1997-05-15 Terrapin Tech Inc Verfahren zur herstellung von imunodiagnose- mitteln
US5133866A (en) * 1988-03-24 1992-07-28 Terrapin Technologies, Inc. Method to identify analyte-bending ligands
US5338659A (en) * 1991-04-02 1994-08-16 Terrapin Technologies, Inc. Method for determining analyte concentration by cross-reactivity profiling
US5599903A (en) * 1992-04-03 1997-02-04 Terrapin Technologies, Inc. Glutathione analogs and paralog panels comprising glutathione mimics
US5217869A (en) * 1987-10-13 1993-06-08 Terrapin Technologies, Inc. Method to produce immunodiagnostic reagents
GB8810400D0 (en) 1988-05-03 1988-06-08 Southern E Analysing polynucleotide sequences
US5340474A (en) * 1988-03-24 1994-08-23 Terrapin Technologies, Inc. Panels of analyte-binding ligands
US5409611A (en) * 1988-03-24 1995-04-25 Terrapin Technoogies, Inc. Method to identify analyte-binding ligands
US5010175A (en) * 1988-05-02 1991-04-23 The Regents Of The University Of California General method for producing and selecting peptides with specific properties
US5266684A (en) * 1988-05-02 1993-11-30 The Reagents Of The University Of California Peptide mixtures
US5225533A (en) * 1988-05-02 1993-07-06 The Regents Of The University Of California General method for producing and selecting peptides with specific properties
US6054270A (en) * 1988-05-03 2000-04-25 Oxford Gene Technology Limited Analying polynucleotide sequences
US7811751B2 (en) 1988-05-03 2010-10-12 Oxford Gene Technology Limited Analysing polynucleotide sequences
US5700637A (en) * 1988-05-03 1997-12-23 Isis Innovation Limited Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
FR2631451A1 (fr) * 1988-05-13 1989-11-17 Inst Nat Sante Rech Med Procede de caracterisation de l'epitope intervenant dans une reaction antigene anticorps, kit ou necessaire pour la mise en oeuvre du procede
US5286789A (en) * 1989-05-26 1994-02-15 Applied Immune Sciences, Inc. Solid phase multiple peptide synthesis
US5547839A (en) 1989-06-07 1996-08-20 Affymax Technologies N.V. Sequencing of surface immobilized polymers utilizing microflourescence detection
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5527681A (en) * 1989-06-07 1996-06-18 Affymax Technologies N.V. Immobilized molecular synthesis of systematically substituted compounds
US20030225254A1 (en) * 1989-08-07 2003-12-04 Rathjen Deborah Ann Tumour necrosis factor binding ligands
DE69027121T3 (de) * 1989-08-07 2001-08-30 Peptech Ltd., Dee Why Bindeligande für tumornekrosisfaktor
US5959087A (en) * 1989-08-07 1999-09-28 Peptide Technology, Ltd. Tumour necrosis factor binding ligands
US5747334A (en) * 1990-02-15 1998-05-05 The University Of North Carolina At Chapel Hill Random peptide library
US5498538A (en) * 1990-02-15 1996-03-12 The University Of North Carolina At Chapel Hill Totally synthetic affinity reagents
US5965695A (en) * 1990-05-15 1999-10-12 Chiron Corporation Modified peptide and peptide libraries with protease resistance, derivatives thereof and methods of producing and screening such
US5252296A (en) * 1990-05-15 1993-10-12 Chiron Corporation Method and apparatus for biopolymer synthesis
US5182366A (en) * 1990-05-15 1993-01-26 Huebner Verena D Controlled synthesis of peptide mixtures using mixed resins
US5650489A (en) * 1990-07-02 1997-07-22 The Arizona Board Of Regents Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
US6197529B1 (en) 1990-11-21 2001-03-06 Torrey Pines Institute For Molecular Studies Linear substituted oligoalkyleneimine libraries
WO1992009300A1 (en) * 1990-11-21 1992-06-11 Iterex Pharmaceuticals Ltd. Partnership Synthesis of equimolar multiple oligomer mixtures, especially of oligopeptide mixtures
US5786336A (en) * 1991-04-29 1998-07-28 Terrapin Technologies, Inc. Target-selective protocols based on mimics
EP0630412B1 (en) * 1991-04-29 1998-11-11 Terrapin Technologies, Inc. Methods to profile and treat abnormal cells
US5667984A (en) * 1991-05-07 1997-09-16 Oxford Glycosystems Ltd. Sequencing of oligosaccharides
TW304957B (no) * 1991-06-18 1997-05-11 Lilly Co Eli
WO1993004204A1 (en) * 1991-08-23 1993-03-04 Isis Pharmaceuticals, Inc. Synthetic unrandomization of oligomer fragments
US5698391A (en) * 1991-08-23 1997-12-16 Isis Pharmaceuticals, Inc. Methods for synthetic unrandomization of oligomer fragments
US5747253A (en) * 1991-08-23 1998-05-05 Isis Pharmaceuticals, Inc. Combinatorial oligomer immunoabsorbant screening assay for transcription factors and other biomolecule binding
US6943034B1 (en) 1991-11-22 2005-09-13 Affymetrix, Inc. Combinatorial strategies for polymer synthesis
US5955432A (en) * 1992-04-03 1999-09-21 Terrapin Technologies, Inc. Metabolic effects of certain glutathione analogs
US5541061A (en) * 1992-04-29 1996-07-30 Affymax Technologies N.V. Methods for screening factorial chemical libraries
US5591646A (en) * 1992-09-02 1997-01-07 Arris Pharmaceutical Method and apparatus for peptide synthesis and screening
US6582902B1 (en) * 1992-09-30 2003-06-24 Jack D. Keene Method for deriving epitopes
US5877278A (en) * 1992-09-24 1999-03-02 Chiron Corporation Synthesis of N-substituted oligomers
US5565324A (en) * 1992-10-01 1996-10-15 The Trustees Of Columbia University In The City Of New York Complex combinatorial chemical libraries encoded with tags
US5721099A (en) * 1992-10-01 1998-02-24 Trustees Of Columbia University In The City Of New York Complex combinatorial chemical libraries encoded with tags
US6503759B1 (en) 1992-10-01 2003-01-07 The Trustees Of Columbia University In The City Of New York Complex combinatorial chemical libraries encoded with tags
US5565325A (en) * 1992-10-30 1996-10-15 Bristol-Myers Squibb Company Iterative methods for screening peptide libraries
US5807683A (en) * 1992-11-19 1998-09-15 Combichem, Inc. Combinatorial libraries and methods for their use
DE4308410A1 (de) * 1993-03-12 1994-09-15 Schering Ag Verfahren zur Synthese und Selektionierung von Sequenzen aus kovalent verbundenen Bausteinen
WO1994020521A1 (de) * 1993-03-12 1994-09-15 Jerini Bio Chemicals Gmbh Verfahren zur synthese und selektionierung von sequenzen aus kovalent verbundenen bausteinen
US6864048B2 (en) * 1993-04-28 2005-03-08 Affymetrix, Inc. Factorial chemical libraries
IT1270939B (it) * 1993-05-11 1997-05-26 Angeletti P Ist Richerche Bio Procedimento per la preparazione di immunogeni e reagenti diagnostici,e immunogeni e reagenti diagnostici cosi' ottenibili.
US5367053A (en) * 1993-05-19 1994-11-22 Houghten Pharmaceuticals, Inc. Opioid peptide inhibitors
US5846731A (en) * 1993-06-17 1998-12-08 Torry Pines Institute For Molecular Studies Peralkylated oligopeptide mixtures
US6008058A (en) * 1993-06-18 1999-12-28 University Of Louisville Cyclic peptide mixtures via side chain or backbone attachment and solid phase synthesis
US5380668A (en) * 1993-07-06 1995-01-10 University Of Utah Research Foundation Compounds having the antigenicity of hCG
CN1525171A (zh) * 1993-10-01 2004-09-01 ŦԼ�и��ױ��Ǵ�ѧ���� 用标示物编码的多元组合化学库
US5908919A (en) * 1993-10-01 1999-06-01 Terrapin Technologies Urethane mediated, GST specific molecular release systems
WO1995010296A1 (en) * 1993-10-12 1995-04-20 Glycomed Incorporated A library of glyco-peptides useful for identification of cell adhesion inhibitors
WO1995013538A1 (en) * 1993-11-12 1995-05-18 Operon Technologies, Inc. Methods of producing and screening complex chemical libraries
US5492807A (en) * 1993-11-19 1996-02-20 Santi; Daniel V. Method of obtaining diagnostic reagents, assays and therapeutics based on clinical manifestations of a disease
US6287787B1 (en) 1993-11-24 2001-09-11 Torrey Pines Institute For Molecular Studies Dimeric oligopeptide mixture sets
WO1995019567A1 (en) * 1994-01-13 1995-07-20 The Trustees Of Columbia University In The City Of New York Synthetic receptors, libraries and uses thereof
US6660276B1 (en) 1994-02-16 2003-12-09 The University Of Virginia Patent Foundation Peptides recognized by melanoma-specific cytotoxic lymphocytes, and uses therefor
US6936477B2 (en) * 1994-04-13 2005-08-30 The Trustees Of Columbia University In The City Of New York Complex combinatorial chemical libraries encoded with tags
US5738996A (en) * 1994-06-15 1998-04-14 Pence, Inc. Combinational library composition and method
US5824483A (en) * 1994-05-18 1998-10-20 Pence Inc. Conformationally-restricted combinatiorial library composition and method
US5846841A (en) * 1994-05-20 1998-12-08 Selectide Corporation Motif Libraries
US5645996A (en) * 1994-08-24 1997-07-08 Torrey Pines Institute For Molecular Studies Melittin-related polypeptides, mixture sets and libraries thereof
US5582997A (en) * 1994-08-24 1996-12-10 Torrey Pines Institute For Molecular Studies Lysine/leucine polypeptides, mixture sets and libraries thereof
US7820798B2 (en) * 1994-11-07 2010-10-26 Human Genome Sciences, Inc. Tumor necrosis factor-gamma
US7597886B2 (en) * 1994-11-07 2009-10-06 Human Genome Sciences, Inc. Tumor necrosis factor-gamma
US5747458A (en) * 1995-06-07 1998-05-05 Chiron Corporation Urokinase receptor ligands
US5958792A (en) * 1995-06-07 1999-09-28 Chiron Corporation Combinatorial libraries of substrate-bound cyclic organic compounds
US5763263A (en) * 1995-11-27 1998-06-09 Dehlinger; Peter J. Method and apparatus for producing position addressable combinatorial libraries
ES2200084T3 (es) * 1995-12-18 2004-03-01 Praecis Pharmaceuticals Incorporated Metodos para identificar compuestos que se unen a una diana.
GB9609262D0 (en) * 1996-05-02 1996-07-03 Isis Innovation Peptide library and method
EP2025682A3 (en) 1996-08-16 2009-06-17 Human Genome Sciences, Inc. Human endokine alpha
JP2001500369A (ja) 1996-08-30 2001-01-16 ヒューマン ジノーム サイエンシーズ，インコーポレイテッド インターロイキン―１９
WO1998014569A1 (en) 1996-10-02 1998-04-09 Bloch Donald B Leukocyte-specific protein and gene, and methods of use thereof
ATE302272T1 (de) 1996-10-25 2005-09-15 Human Genome Sciences Inc Neutrokin alpha
US6025371A (en) * 1996-10-28 2000-02-15 Versicor, Inc. Solid phase and combinatorial library syntheses of fused 2,4-pyrimidinediones
US6413724B1 (en) 1996-10-28 2002-07-02 Versicor, Inc. Solid phase and combinatorial library syntheses of fused 2,4-pyrimidinediones
DE69737125T3 (de) 1996-10-31 2015-02-26 Human Genome Sciences, Inc. Streptococcus pneumoniae-Antigene und Impfstoffe
US6544523B1 (en) 1996-11-13 2003-04-08 Chiron Corporation Mutant forms of Fas ligand and uses thereof
WO1998029736A1 (en) 1996-12-31 1998-07-09 Genometrix Incorporated Multiplexed molecular analysis apparatus and method
AU9482498A (en) 1997-09-17 1999-04-05 Human Genome Sciences, Inc. Interleukin-17 receptor-like protein
KR20010031713A (ko) 1997-11-03 2001-04-16 벤슨 로버트 에이치. 맥관형성 및 종양 성장 억제제인 맥관 내피 세포 성장억제제
AU1417999A (en) * 1997-11-21 1999-06-15 Human Genome Sciences, Inc. Chemokine alpha-5
US20030096232A1 (en) 1997-12-19 2003-05-22 Kris Richard M. High throughput assay system
US6562844B2 (en) 1998-01-23 2003-05-13 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
EP1049682A1 (en) 1998-01-23 2000-11-08 Versicor, Inc. Oxazolidinone combinatorial libraries, compositions and methods of preparation
US7002020B1 (en) 1998-01-23 2006-02-21 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
JP2002506625A (ja) 1998-03-19 2002-03-05 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド サイトカインレセプター共通γ鎖様
HUP0104306A2 (hu) * 1998-11-13 2002-03-28 Pepscan Systems B.V. Eljárás mimotóp szekvencia meghatározására
JP2002537769A (ja) 1999-02-26 2002-11-12 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド ヒトエンドカインαおよび使用方法
US6432409B1 (en) * 1999-09-14 2002-08-13 Antigen Express, Inc. Hybrid peptides modulate the immune response
US9289487B2 (en) * 1999-09-14 2016-03-22 Antigen Express, Inc. II-key/antigenic epitope hybrid peptide vaccines
US6545032B1 (en) 1999-09-17 2003-04-08 Torrey Pines Institute For Molecular Studies Synthesis of [3,5,7]-H-imidazo[1,5-a] imidazol-2(3H)-one compounds
DE60043197D1 (no) 1999-11-18 2009-12-03 Univ Kyoto
US20020082205A1 (en) 2000-03-08 2002-06-27 Nobuyuki Itoh Human FGF-23 gene and gene expression products
US20020110843A1 (en) * 2000-05-12 2002-08-15 Dumas David P. Compositions and methods for epitope mapping
US6759510B1 (en) 2000-06-30 2004-07-06 Becton, Dickinson And Company Peptides for use in culture media
AUPR279101A0 (en) * 2001-01-30 2001-02-22 Cytopia Pty Ltd Protein kinase signalling
EP1377664A2 (en) 2001-02-23 2004-01-07 DSM IP Assets B.V. Genes encoding proteolytic enzymes from aspargilli
DK1385864T3 (da) 2001-04-13 2010-08-16 Human Genome Sciences Inc Anti-VEGF-2-antistoffer
US20030013208A1 (en) * 2001-07-13 2003-01-16 Milagen, Inc. Information enhanced antibody arrays
EP1482963A4 (en) * 2002-03-08 2010-06-09 Univ Texas CONTROLLED MODULATION OF LATERAL CHAIN LENGTH OF AMINO ACIDS OF ANTIGENS PEPTIDES
CN100545261C (zh) 2002-05-21 2009-09-30 Dsmip资产有限公司 新的磷脂酶及其用途
CN1675355A (zh) 2002-08-19 2005-09-28 帝斯曼知识产权资产管理有限公司 新颖的脂肪酶及其用途
EP1545578A4 (en) 2002-08-28 2010-07-07 Immunex Corp COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISEASES
US7179645B2 (en) * 2002-09-24 2007-02-20 Antigen Express, Inc. Ii-Key/antigenic epitope hybrid peptide vaccines
AU2003294220A1 (en) 2002-09-17 2004-04-23 Antigen Express, Inc. Ii-KEY/ANTIGENIC EPITOPE HYBRID PEPTIDE VACCINES
US6910785B2 (en) * 2003-01-22 2005-06-28 Cooper Technologies Company Industrial luminaire with prismatic refractor
US20040185499A1 (en) * 2003-03-20 2004-09-23 Jolley Michael E. Method of epitope scanning using fluorescence polarization
WO2005012530A2 (en) 2003-07-25 2005-02-10 Amgen Inc. Antagonists and agonists of ldcam and methods of use
US7396940B2 (en) 2003-10-23 2008-07-08 Hoffmann-La Roche Inc. Combinatorial library of 3-aryl-1H-indole-2-carboxylic acid
US20050095648A1 (en) * 2003-10-30 2005-05-05 Mario Geysen Method for designing linear epitopes and algorithm therefor and polypeptide epitopes
CA2574654C (en) 2004-07-22 2014-02-18 Five Prime Therapeutics, Inc. Compositions and methods of use for mgd-csf in disease treatment
US8945573B2 (en) 2005-09-08 2015-02-03 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Targeted identification of immunogenic peptides
US20120208824A1 (en) 2006-01-20 2012-08-16 Cell Signaling Technology, Inc. ROS Kinase in Lung Cancer
EP3360965A1 (en) 2006-01-20 2018-08-15 Cell Signaling Technology, Inc. Translocation and mutant ros kinase in human non-small cell lung carcinoma
SI2450437T1 (sl) 2006-04-14 2017-12-29 Cell Signaling Technology Inc. Okvarjenost genov in mutantna ALK kinaza v človeških solidnih tumorjih
US20080261226A1 (en) * 2007-02-15 2008-10-23 Rengang Wang Biomarkers of neurodegenerative disease
WO2008116092A1 (en) 2007-03-20 2008-09-25 Brandeis University Compositions and methods for the diagnosis, treatment, and prevention of amyotrophic lateral sclerosis and related neurological diseases
US8071378B2 (en) 2007-08-06 2011-12-06 Sanford-Burnham Medical Research Institute ZNF206: regulator of embryonic stem cell self-renewal and pluripotency
ES2576650T3 (es) 2007-10-18 2016-07-08 Cell Signaling Technology, Inc. Translocación y ROS quinasa mutante en el carcinoma pulmonar no microcítico humano
WO2009158432A2 (en) 2008-06-27 2009-12-30 Amgen Inc. Ang-2 inhibition to treat multiple sclerosis
JP2012516350A (ja) * 2009-01-28 2012-07-19 アンティジェン・エクスプレス・インコーポレーテッド インフルエンザに対する免疫応答を調節するＩｉ−Ｋｅｙハイブリッドペプチド
SI2881402T1 (sl) 2009-02-12 2017-12-29 Cell Signaling Technology, Inc. Ekspresija mutantnega ros pri humanem raku jeter
NZ795881A (en) 2009-08-27 2024-07-05 Pastoral Greenhouse Gas Res Ltd Complete genome sequence of the methanogen methanobrevibacter ruminantium
US20120101108A1 (en) 2010-08-06 2012-04-26 Cell Signaling Technology, Inc. Anaplastic Lymphoma Kinase In Kidney Cancer
HUE037856T2 (hu) 2012-04-18 2018-09-28 Cell Signaling Technology Inc EGFR és ROS1 rákban
US10155987B2 (en) 2012-06-12 2018-12-18 Dana-Farber Cancer Institute, Inc. Methods of predicting resistance to JAK inhibitor therapy
EP3765069A1 (en) * 2018-03-16 2021-01-20 Zoetis Services LLC Peptide vaccines against interleukin-31

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3949064A (en) * 1973-10-26 1976-04-06 Baxter Laboratories, Inc. Method of detecting antigens or antibodies
US4415491A (en) * 1980-01-14 1983-11-15 The Regents Of The University Of California Synthetic vaccine peptide epitomes of hepatitis B surface antigen
US4554101A (en) * 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
US4591552A (en) * 1982-09-29 1986-05-27 New York Blood Center, Inc. Detection of hepatitis B surface antigen (or antibody to same) with labeled synthetic peptide
JP2598893B2 (ja) * 1983-01-21 1997-04-09 プリマス，フレデリック ジェームス 特異性ｃｅａファミリー抗原に対し特異性の抗体を使用するイム／アッセイ
NZ207394A (en) * 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids
AU573574B2 (en) * 1983-03-08 1988-06-16 Chiron Mimotopes Pty Ltd Immunogenic deteminants of foot and mouth disease virus
US4578217A (en) * 1983-05-12 1986-03-25 New York Blood Center, Inc. Synthetic antigenic peptide derived from hepatitis B surface antigen
US4493795A (en) * 1983-10-17 1985-01-15 Syntex (U.S.A.) Inc. Synthetic peptide sequences useful in biological and pharmaceutical applications and methods of manufacture
JPH0720884B2 (ja) * 1983-11-07 1995-03-08 ザ・ウイスタ−・インスティテュ−ト 抗イデイオタイプ抗体によって誘発される、腫瘍およびウイルスに対する免疫応答
ATE45285T1 (de) * 1983-11-07 1989-08-15 Wistar Inst Durch antiidiotype antikoerper induzierte immune antwort zu tumoren und viren.
US5266684A (en) * 1988-05-02 1993-11-30 The Reagents Of The University Of California Peptide mixtures

Also Published As

Publication number Publication date
DK136086A (da) 1986-03-24
JPH09183796A (ja) 1997-07-15
EP0190205B1 (en) 1992-10-21
ATE81722T1 (de) 1992-11-15
MY102885A (en) 1993-03-31
DE3586772D1 (de) 1992-11-26
JPH07260783A (ja) 1995-10-13
DE3586772T2 (de) 1993-03-04
NO166465B (no) 1991-04-15
CA1255586A (en) 1989-06-13
EP0190205A4 (en) 1988-01-28
WO1986000991A1 (en) 1986-02-13
NO166465C (no) 1991-07-24
JPS61502839A (ja) 1986-12-04
DK164942B (da) 1992-09-14
US5998577A (en) 1999-12-07
US5194392A (en) 1993-03-16
DK136086D0 (da) 1986-03-24
NO861104L (no) 1986-05-16
EP0190205A1 (en) 1986-08-13
JPH07119760B2 (ja) 1995-12-20
JP2796962B2 (ja) 1998-09-10
JP2640438B2 (ja) 1997-08-13

Similar Documents

Publication Publication Date Title
DK164942C (da) Fremgangsmaade til bestemmelse af en sekvens af monomerer, der er aekvivalent med en epitop paa et antigen
DK165197C (da) Fremgangsmaade til bestemmelse af mimotoper
DK163839C (da) Fremgangsmaade til bestemmelse af antigener ved hjaelp af tre eller flere monoklonale antistoffer, og et proeveudstyr til brug ved fremgangsmaaden
DK158284A (da) Monoklonale antistoffer afledt af tvaerbundne fibrinderivater samt analysemetode til bestemmelse af disse derivater
DK99682A (da) Immunoanalysemetoder under anvendelse af monoklonale antistoffer
DK405084A (da) Proeveudstyr til detektering af antistoffer for htlv-antigener i humant serum og fremgangsmaade til fremstilling af et saadant udstyr
ATE152244T1 (de) Verfahren zur herstellung von imunodiagnose- mitteln
DK553281A (da) Fremgangsmaade til paavisning af antistof
DK51481A (da) Fremgangsmaade til bestemmelse af carcinoembryonisk antigen
DE3571504D1 (en) Method for immunologically measuring antigens, antibodies or haptens, the use of this method for measuring lipoproteins and alpha-fetoprotein and test kits for the performance of this method
DK559187A (da) Immunkemisk kompetitiv fremgangsmaade til paavisning af antistoffer mod hiv, analysesaet hertil og anvendelse heraf
DE69033352D1 (de) Competitives enzym-testverfahren zum nachweis von phosphothioaten
DK169381A (da) Fremgangsmaade til detektion af en blodgruppes antigener og m2ddel til udoevelse af fremgangsmaaden
DK230485D0 (da) Fremgangsmaade til bestemmelse af atl virusantistof og reagens dertil
CA2095735A1 (en) Monoclonal antibodies to hepatitis c virus and method for using same
DK98692A (da) Monoklonalt antistof og fremgangsmaade til fremstilling deraf, hybridoma, som producerer det monoklonale antistof, og proeve for tumorcellefoelsomhed under anvendelse af det monoklonale antistof
DK276185D0 (da) Monoklonale antistoffer,fremgangsmaade til fremstilling af disse samt deres diagnostiske anvendelse
ES552074A0 (es) Un metodo en emparedado de doble anticuerpo para detectar o ensayar un antigeno seleccionado de urocinasa humana y un precursor de la misma
ATE122150T1 (de) Einschritt-immuntest zur bestimmung von antigen- spezifischen antikörpern aller immunglobulin- klassen und dazu geeignetes mittel.
BR8803673A (pt) Hibridoma,mutantes,anticorpo,processos para a preparacao de um hidroma e para a preparacao de um anticorpo,processo para determinacao da existencia de antigeno e kit de teste
DK159297C (da) Fremgangsmaade til immunokemisk bestemmelse af hepatitis b kerneantigener og forsoegsudstyr og immunokemisk reagens til brug ved denne fremgangsmaade
DK494084A (da) Hybridoma, monokloniske antistoffer frembragt hermed og diagnosemetode under anvendelse af disse
IL71508A0 (en) Specific binding assay method and test kit for the determination of haptens,antigens and antibodies
RU94043032A (ru) Способ индикации бактериальных антигенов
GB2248937A (en) An immunological method of monitoring soundness of timber

Legal Events

Date Code Title Description
PBP Patent lapsed