DK158284A - Monoklonale antistoffer afledt af tvaerbundne fibrinderivater samt analysemetode til bestemmelse af disse derivater - Google Patents

Monoklonale antistoffer afledt af tvaerbundne fibrinderivater samt analysemetode til bestemmelse af disse derivater Download PDF

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Publication number
DK158284A
DK158284A DK158284A DK158284A DK158284A DK 158284 A DK158284 A DK 158284A DK 158284 A DK158284 A DK 158284A DK 158284 A DK158284 A DK 158284A DK 158284 A DK158284 A DK 158284A
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Denmark
Prior art keywords
derivative
crosslinked fibrin
derivatives
fibrin derivative
extract
Prior art date
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DK158284A
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English (en)
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DK158284D0 (da
Inventor
Peter Gregory Bundesen
Dennis Brian Rylatt
Original Assignee
Fielder Gillespie Davis Ltd
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Application filed by Fielder Gillespie Davis Ltd filed Critical Fielder Gillespie Davis Ltd
Publication of DK158284D0 publication Critical patent/DK158284D0/da
Publication of DK158284A publication Critical patent/DK158284A/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G01N2333/75—Fibrin; Fibrinogen

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK158284A 1983-03-17 1984-03-16 Monoklonale antistoffer afledt af tvaerbundne fibrinderivater samt analysemetode til bestemmelse af disse derivater DK158284A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPF849483 1983-03-17

Publications (2)

Publication Number Publication Date
DK158284D0 DK158284D0 (da) 1984-03-16
DK158284A true DK158284A (da) 1984-09-18

Family

ID=3770042

Family Applications (1)

Application Number Title Priority Date Filing Date
DK158284A DK158284A (da) 1983-03-17 1984-03-16 Monoklonale antistoffer afledt af tvaerbundne fibrinderivater samt analysemetode til bestemmelse af disse derivater

Country Status (18)

Country Link
US (1) US4758524A (da)
EP (1) EP0122478B2 (da)
JP (1) JPS59183696A (da)
KR (1) KR840008288A (da)
AT (1) ATE99738T1 (da)
AU (1) AU572125B2 (da)
CA (1) CA1247022A (da)
DE (1) DE3486262T3 (da)
DK (1) DK158284A (da)
ES (1) ES530691A0 (da)
GR (1) GR81951B (da)
IL (1) IL71264A (da)
IN (1) IN158324B (da)
NO (1) NO167338C (da)
NZ (1) NZ207459A (da)
PH (1) PH22957A (da)
PT (1) PT78267B (da)
ZA (1) ZA841878B (da)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4722903A (en) * 1983-11-14 1988-02-02 New York Blood Center, Inc. Monoclonal antibodies specific to in vivo fragments derived from human fibrinogen, human fiberin I or human fibrin II
DE3400434A1 (de) * 1984-01-09 1985-09-26 Behringwerke Ag, 3550 Marburg Bestimmung von fibrin mit fibrin-spezifischen antikoerpern
JPS60166698A (ja) * 1984-02-09 1985-08-29 Dai Ichi Pure Chem Co Ltd モノクロ−ナル抗体
US4927916A (en) * 1984-04-23 1990-05-22 The General Hospital Corporation Method of producing fibrin-specific monoclonal antibodies lacking fibrinogen-cross-reactivity using fibrin-specific peptides
US5357042A (en) * 1984-04-23 1994-10-18 The General Hospital Corporation Synthetic peptides capable of eliciting fibrin-specific monoclonal antibodies lacking fibrinogen-cross-reactivity
FR2569276B1 (fr) * 1984-08-14 1988-02-05 Stago Diagnostica Procede de dosage de produits de degradation du fibrinogene
US5116613A (en) * 1985-01-08 1992-05-26 The General Hospital Corporation Antibody-thrombolytic agent product and method of use
US4775624A (en) * 1985-02-08 1988-10-04 Eli Lilly And Company Vectors and compounds for expression of human protein C
FR2593518B1 (fr) * 1985-05-02 1989-09-08 Transgene Sa Vecteurs d'expression et de secretion de l'hirudine par les levures transformees
US4916070A (en) * 1986-04-14 1990-04-10 The General Hospital Corporation Fibrin-specific antibodies and method of screening for the antibodies
JPH0746104B2 (ja) * 1986-09-22 1995-05-17 株式会社ヤトロン Ｆｄｐの測定法
US5102787A (en) * 1987-07-10 1992-04-07 Miho Sasamata Method, device and kit for measurement of tissue plasminogen activator activity
US5582862A (en) * 1988-04-04 1996-12-10 General Hospital Corporation Antibodies that bind to α2-antiplasmin crosslinked to fibrin which do not inhibit plasma α2-antiplasmin
US5372812A (en) * 1988-04-04 1994-12-13 The General Hospital Corporation Composition and method for acceleration of clot lysis
US5453359A (en) 1988-06-13 1995-09-26 American Biogenetic Sciences, Inc. Immunoassay and kit for in vitro detection of soluble DesAABB fibrin polymers
US5120834A (en) * 1988-06-13 1992-06-09 American Biogenetic Sciences, Inc. Fibrin-specific monoclonal antibody
US5206140A (en) * 1988-06-24 1993-04-27 Research Corporation Technologies, Inc. Assay for soluble crosslinked fibrin polymers
IE67430B1 (en) * 1988-06-24 1996-04-03 Res Corp Technologies Inc Assay for soluble crosslinked fibrin polymers
US5609869A (en) * 1988-08-19 1997-03-11 The General Hospital Corporation Hybrid immunoglobulin-thrombolytic enzyme molecules which specifically bind a thrombus, and methods of their production and use
US5811265A (en) * 1988-08-19 1998-09-22 The General Hospital Corporation Hybrid immunoglobulin-thrombolytic enzyme molecules which specifically bind a thrombus, and methods of their production and use
CA2023354C (en) * 1989-08-17 2002-08-13 Karen Ann Thomas Method for direct chemical binding of d-dimer from a biological sample for diagnosing and monitoring thrombolytic and hypercoagulable states
EP0489061A4 (en) * 1989-08-24 1992-10-14 Australian Nuclear Science And Technology Organisation Radio-labelled antibodies for imaging
FR2663748B1 (fr) * 1990-06-22 1992-10-09 Oris Ind Cie Anticorps specifiques de la liaison isopeptidique induite par les transglutaminases, antigenes constitues par des isopeptides glu-lys reconnus par lesdits anticorps, agents de diagnostic et compositions therapeutiques les contenant.
PT590766E (pt) * 1992-07-31 2000-07-31 Australian Nuclear Science Tec Complexos metalicos de hidroxiarilo contendo agentes quelantes de acido aminocarboxilico
US5807535A (en) * 1992-07-31 1998-09-15 Australian Nuclear Science & Technology Organisation Metal complexes of hydroxyaryl containing aminocarboxylic acid chelating agents
US5487892A (en) * 1994-02-24 1996-01-30 American Biogenetic Sciences, Inc. Method for treating thrombotic disease using a fibrin specific monoclonal antibody
CA2266341A1 (en) * 1996-09-20 1998-03-26 The General Hospital Corporation Composition and method for enhancing fibrinolysis using antibodies to alpha-2-antiplasmin
AU2002232518A1 (en) * 2000-11-13 2002-05-21 Sigma-Aldrich Co. Improved assay and reagents or immunological determination of analyte concentration
US20030003515A1 (en) * 2000-12-05 2003-01-02 Farrell David H. Monocloral antibody-based diagnostic assay for gamma fibrinogen
NZ530122A (en) * 2001-06-26 2008-03-28 Agen Biomedical Ltd Variant of an immunointeractive molecule comprising a portion having specificity for cross-linked fibrin derivatives from an immunointeractive molecule from an animal or avian
US20030224476A1 (en) * 2002-03-01 2003-12-04 Szu-Yi Chou Method of producing transglutaminase reactive compound
US20040001848A1 (en) * 2002-03-01 2004-01-01 Szu-Yi Chou Method of producing disease-specific antigens
US7485438B2 (en) * 2002-03-01 2009-02-03 Szu-Yi Chou Method of producing polyvalent antigens
US20030219853A1 (en) * 2002-03-01 2003-11-27 Szu-Yi Chou Method of cross-linking a compound
DE102004052082A1 (de) 2004-10-26 2006-04-27 Dade Behring Marburg Gmbh Durchstoßbare, flexible Vorrichtung zur Abdeckung von Flüssigkeitsbehältnissen
US11506674B2 (en) 2005-07-29 2022-11-22 Princeton Biomeditech Corporation Monoclonal antibody against D-dimer and diagnosis agent for detecting D-dimer, crosslinked fibrin and its derivatives containing D-dimer by using the antibody
US8940489B2 (en) 2005-07-29 2015-01-27 Hyun-Ju Doh Monoclonal antibody against D-dimer and diagnosis agent for detecting D-dimer, crosslinked fibrin and its derivatives containing D-dimer by using the antibody
US9206250B2 (en) 2010-04-01 2015-12-08 Lsi Medience Corporation Monoclonal antibodies and method of immunological analysis of D-dimer
WO2012014996A1 (ja) * 2010-07-30 2012-02-02 シスメックス株式会社 Ｆｄｐ測定用試薬及び試薬キット、並びに測定方法
TWI658268B (zh) * 2017-11-29 2019-05-01 國立清華大學 血液檢測方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196265A (en) * 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
EP0113075A3 (en) * 1982-12-06 1985-05-02 Fielder Gillespie Davis Limited Field immunoassay reaction system, method of immunoassay diagnosis and probe or carrier for use therewith
AU2373384A (en) * 1982-12-06 1984-06-14 Fielder Gillespie Davis Ltd. Field immunoassay reaction system
US4722903A (en) * 1983-11-14 1988-02-02 New York Blood Center, Inc. Monoclonal antibodies specific to in vivo fragments derived from human fibrinogen, human fiberin I or human fibrin II

Also Published As

Publication number Publication date
JPS59183696A (ja) 1984-10-18
DK158284D0 (da) 1984-03-16
AU572125B2 (en) 1988-05-05
ES8507694A1 (es) 1985-09-01
PH22957A (en) 1989-02-03
PT78267B (en) 1986-04-21
NO841023L (no) 1984-09-18
JPH0583240B2 (da) 1993-11-25
CA1247022A (en) 1988-12-20
DE3486262T2 (de) 1994-06-16
US4758524A (en) 1988-07-19
EP0122478B1 (en) 1994-01-05
IL71264A (en) 1987-10-20
DE3486262D1 (de) 1994-02-17
IN158324B (da) 1986-10-18
EP0122478A2 (en) 1984-10-24
GR81951B (da) 1984-12-12
DE3486262T3 (de) 2000-10-26
IL71264A0 (en) 1984-06-29
NO167338B (no) 1991-07-15
ES530691A0 (es) 1985-09-01
AU2538784A (en) 1984-09-20
ATE99738T1 (de) 1994-01-15
KR840008288A (ko) 1984-12-14
PT78267A (en) 1984-04-01
ZA841878B (en) 1984-10-31
NZ207459A (en) 1987-11-27
EP0122478A3 (en) 1987-04-01
NO167338C (no) 1993-12-15
EP0122478B2 (en) 2000-04-12

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