ATE189396T1 - Hydroxyaryl enthaltenden aminocarboxylsäure- chelatbildnern - Google Patents
Hydroxyaryl enthaltenden aminocarboxylsäure- chelatbildnernInfo
- Publication number
- ATE189396T1 ATE189396T1 AT93305992T AT93305992T ATE189396T1 AT E189396 T1 ATE189396 T1 AT E189396T1 AT 93305992 T AT93305992 T AT 93305992T AT 93305992 T AT93305992 T AT 93305992T AT E189396 T1 ATE189396 T1 AT E189396T1
- Authority
- AT
- Austria
- Prior art keywords
- sulphamoyl
- carbamoyl
- integer
- aminocarboxylic acid
- hydroxy
- Prior art date
Links
- KXDHJXZQYSOELW-UHFFFAOYSA-N Carbamic acid Chemical compound NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 title 1
- 239000002738 chelating agent Substances 0.000 title 1
- -1 hydroxy, mercapto, nitro, cyano, thiocyano Chemical group 0.000 abstract 6
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- SMWDFEZZVXVKRB-UHFFFAOYSA-N anhydrous quinoline Natural products N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPL388392 | 1992-07-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE189396T1 true ATE189396T1 (de) | 2000-02-15 |
Family
ID=3776332
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93305992T ATE189396T1 (de) | 1992-07-31 | 1993-07-29 | Hydroxyaryl enthaltenden aminocarboxylsäure- chelatbildnern |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5550160A (de) |
| EP (2) | EP0955066A3 (de) |
| JP (1) | JPH07285888A (de) |
| AT (1) | ATE189396T1 (de) |
| DE (1) | DE69327760T2 (de) |
| ES (1) | ES2146217T3 (de) |
| GR (1) | GR3033352T3 (de) |
| PT (1) | PT590766E (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5807535A (en) * | 1992-07-31 | 1998-09-15 | Australian Nuclear Science & Technology Organisation | Metal complexes of hydroxyaryl containing aminocarboxylic acid chelating agents |
| FR2794032B1 (fr) | 1999-05-27 | 2002-06-14 | Univ Claude Bernard Lyon | Procede pour separer en milieu aqueux des lanthanides et/ou des actinides par complexation-nanofiltration, et nouveaux complexants mis en oeuvre dans ce procede |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3632637A (en) * | 1968-02-13 | 1972-01-04 | Arthur E Martell | Hydroxyaryl-containing aminocarboxylic chelating agents |
| BE786946A (fr) * | 1971-07-29 | 1973-01-29 | Ciba Geigy | Chelates pour combattre des symptomes de carences en metaux dans des systemes biologiques |
| FR2515046B1 (fr) * | 1981-10-27 | 1985-11-29 | Hybritech Inc | Anticorps monoclonaux marques par un radionucleide et leur application a la visualisation d'une tumeur |
| CA1222691A (en) * | 1981-12-29 | 1987-06-09 | Wilhelmus T. Goedemans | Method of preparing radionuclide-labelled proteins, in particular antibodies or antibody fragments |
| US4479930A (en) * | 1982-07-26 | 1984-10-30 | Trustees Of The University Of Massachusetts | Amines coupled wth dicyclic dianhydrides capable of being radiolabeled product |
| AU572125B2 (en) * | 1983-03-17 | 1988-05-05 | Mabco Limited | Monoclonal antibodies with specificity for crosslinked fibrin and their diagnotic uses |
| US4652440A (en) * | 1984-05-03 | 1987-03-24 | Paik Chang H | Method of stably radiolabeling antibodies with technetium and rhenium |
| GB8603537D0 (en) * | 1986-02-13 | 1986-03-19 | Parker D | Conjugate compound |
| DE3640708C2 (de) * | 1986-11-28 | 1995-05-18 | Schering Ag | Verbesserte metallhaltige Pharmazeutika |
| DE3713842A1 (de) * | 1987-04-22 | 1988-11-17 | Schering Ag | Substituierte cyclische komplexbildner, komplexe und komplexsalze, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel |
| GB8719041D0 (en) * | 1987-08-12 | 1987-09-16 | Parker D | Conjugate compounds |
| GB8719042D0 (en) * | 1987-08-12 | 1987-09-16 | Parker D | Conjugate compounds |
| IL87405A0 (en) * | 1987-08-12 | 1989-01-31 | Immunomedics Inc | Radiolabeled agents and methods and kits for the production thereof |
| WO1989011475A1 (en) * | 1988-05-25 | 1989-11-30 | The United States Of America, As Represented By Th | Macrocyclic chelates and methods of use thereof |
| US5094950A (en) * | 1988-06-07 | 1992-03-10 | Nihon Medi-Physics Co., Ltd. | Diethylenetriamine pentaacetic acid derivatives |
| JP2776953B2 (ja) * | 1990-04-10 | 1998-07-16 | 日本メジフィジックス株式会社 | 多官能性金属キレート化合物とその用途 |
| GB9027922D0 (en) * | 1990-12-21 | 1991-02-13 | Nycomed As | Compounds |
-
1993
- 1993-07-29 PT PT93305992T patent/PT590766E/pt unknown
- 1993-07-29 EP EP99112338A patent/EP0955066A3/de not_active Withdrawn
- 1993-07-29 DE DE69327760T patent/DE69327760T2/de not_active Expired - Fee Related
- 1993-07-29 EP EP93305992A patent/EP0590766B1/de not_active Expired - Lifetime
- 1993-07-29 US US08/099,179 patent/US5550160A/en not_active Expired - Fee Related
- 1993-07-29 AT AT93305992T patent/ATE189396T1/de not_active IP Right Cessation
- 1993-07-29 ES ES93305992T patent/ES2146217T3/es not_active Expired - Lifetime
- 1993-07-31 JP JP5208689A patent/JPH07285888A/ja active Pending
-
2000
- 2000-05-02 GR GR20000401036T patent/GR3033352T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0955066A3 (de) | 2002-08-28 |
| PT590766E (pt) | 2000-07-31 |
| GR3033352T3 (en) | 2000-09-29 |
| ES2146217T3 (es) | 2000-08-01 |
| DE69327760D1 (de) | 2000-03-09 |
| EP0590766A3 (en) | 1994-08-24 |
| DE69327760T2 (de) | 2000-09-07 |
| EP0590766B1 (de) | 2000-02-02 |
| EP0590766A2 (de) | 1994-04-06 |
| EP0955066A2 (de) | 1999-11-10 |
| US5550160A (en) | 1996-08-27 |
| JPH07285888A (ja) | 1995-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |