DK163929C - Fremgangsmaade til deformylering og fraskillelse af n-formyl-aspartam fra en isomerblanding deraf - Google Patents

Fremgangsmaade til deformylering og fraskillelse af n-formyl-aspartam fra en isomerblanding deraf

Info

Publication number
DK163929C
DK163929C DK381984A DK381984A DK163929C DK 163929 C DK163929 C DK 163929C DK 381984 A DK381984 A DK 381984A DK 381984 A DK381984 A DK 381984A DK 163929 C DK163929 C DK 163929C
Authority
DK
Denmark
Prior art keywords
aspartam
formyl
deformation
separation
procedure
Prior art date
Application number
DK381984A
Other languages
Danish (da)
English (en)
Other versions
DK381984A (da
DK163929B (da
DK381984D0 (da
Inventor
Franco Dallatomasina
Roberto Ortica
Pietro Giardino
Ernesto Oppici
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of DK381984D0 publication Critical patent/DK381984D0/da
Publication of DK381984A publication Critical patent/DK381984A/da
Publication of DK163929B publication Critical patent/DK163929B/da
Application granted granted Critical
Publication of DK163929C publication Critical patent/DK163929C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Seasonings (AREA)
DK381984A 1983-08-12 1984-08-08 Fremgangsmaade til deformylering og fraskillelse af n-formyl-aspartam fra en isomerblanding deraf DK163929C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB838321802A GB8321802D0 (en) 1983-08-12 1983-08-12 Aspartame synthesis
GB8321802 1983-08-12

Publications (4)

Publication Number Publication Date
DK381984D0 DK381984D0 (da) 1984-08-08
DK381984A DK381984A (da) 1985-02-13
DK163929B DK163929B (da) 1992-04-21
DK163929C true DK163929C (da) 1992-09-14

Family

ID=10547240

Family Applications (1)

Application Number Title Priority Date Filing Date
DK381984A DK163929C (da) 1983-08-12 1984-08-08 Fremgangsmaade til deformylering og fraskillelse af n-formyl-aspartam fra en isomerblanding deraf

Country Status (19)

Country Link
US (1) US4549987A (el)
JP (1) JPH0676435B2 (el)
AT (1) AT387025B (el)
AU (1) AU561635B2 (el)
BE (1) BE900317A (el)
CA (1) CA1243668A (el)
CH (1) CH660013A5 (el)
DE (1) DE3428979A1 (el)
DK (1) DK163929C (el)
FI (1) FI81364C (el)
FR (1) FR2550538B1 (el)
GB (2) GB8321802D0 (el)
GR (1) GR80045B (el)
IL (1) IL72621A (el)
IT (1) IT1209577B (el)
NL (1) NL8402480A (el)
SE (1) SE466258B (el)
SU (1) SU1299515A3 (el)
ZA (1) ZA846148B (el)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8616873D0 (en) * 1986-07-10 1986-08-20 British Telecomm Optical telecommunications system
DE3635582A1 (de) * 1986-10-20 1988-04-21 Hoechst Ag Verfahren zur reinigung von n-acyl-aspartam
US4992272A (en) * 1987-03-09 1991-02-12 Diamond Scientific Canine distemper virus vaccine
NL8701035A (nl) * 1987-05-01 1988-12-01 Stamicarbon Werkwijze voor de bereiding van aspartylfenylalaninemethylester uit n-formylaspartylfenylalaninemethylester.
JP2662287B2 (ja) * 1988-03-14 1997-10-08 三井東圧化学株式会社 α―Ｌ―アスパルチル―Ｌ―フェニルアラニンメチルエステルの分離方法
US5283357A (en) * 1988-03-14 1994-02-01 Mitsui Toatsu Chemicals, Incorporated Separation method of α-l-aspartyl-l-phenylalanine methyl ester
JP2979761B2 (ja) * 1991-05-23 1999-11-15 味の素株式会社 α−Ｌ−アスパルチル−Ｌ−フェニルアラニンメチルエステル塩酸塩の製造法
US20080314872A1 (en) * 2007-06-19 2008-12-25 Ferro Corporation Chemical-Mechanical Polishing Compositions Containing Aspartame And Methods Of Making And Using The Same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1117134B (de) * 1960-06-04 1961-11-16 Berlin Chemie Veb Verfahren zur Herstellung von Peptiden unter Verwendung einer oxydativ entfernbaren Schutzgruppe
US3492131A (en) * 1966-04-18 1970-01-27 Searle & Co Peptide sweetening agents
GB1309605A (en) * 1970-01-31 1973-03-14 Ajinomoto Kk Process for producing alpha-dipeptide esters of l-aspartic acid
FR2078640A5 (en) * 1970-02-21 1971-11-05 Beecham Group Ltd Alpha-asparaginyl dipeptides prepn
BE791544A (fr) * 1971-11-19 1973-05-17 Stamicarbon Preparation d'esters alkyliques de dipeptide
US3933781A (en) * 1973-11-05 1976-01-20 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine alkyl esters
JPS5223001A (en) * 1975-08-14 1977-02-21 Ajinomoto Co Inc Process for elimination of formyl group
MX4704E (es) * 1976-12-27 1982-08-04 Monsanto Co Procedimiento mejorado para la preparacion de ester metilico de alfa-l-aspartil-l-fenilalanina
JPS57131746A (en) * 1981-02-10 1982-08-14 Ajinomoto Co Inc Removal of n-formyl group
JPS58185545A (ja) * 1982-04-22 1983-10-29 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルまたはその塩酸塩の製法

Also Published As

Publication number Publication date
IT1209577B (it) 1989-08-30
AU561635B2 (en) 1987-05-14
FI81364B (fi) 1990-06-29
IT8422233A0 (it) 1984-08-06
SE466258B (sv) 1992-01-20
DK381984A (da) 1985-02-13
US4549987A (en) 1985-10-29
JPH0676435B2 (ja) 1994-09-28
GR80045B (en) 1984-12-10
DE3428979C2 (el) 1990-09-06
CH660013A5 (it) 1987-03-13
JPS6067497A (ja) 1985-04-17
GB8420238D0 (en) 1984-09-12
FI81364C (fi) 1990-10-10
ATA253784A (de) 1988-04-15
FI843112A0 (fi) 1984-08-08
NL8402480A (nl) 1985-03-01
BE900317A (fr) 1984-12-03
IL72621A (en) 1987-12-20
AU3168484A (en) 1985-02-14
ZA846148B (en) 1985-03-27
GB2144748A (en) 1985-03-13
DK163929B (da) 1992-04-21
FR2550538A1 (fr) 1985-02-15
FR2550538B1 (fr) 1988-03-04
DK381984D0 (da) 1984-08-08
DE3428979A1 (de) 1985-02-21
CA1243668A (en) 1988-10-25
GB8321802D0 (en) 1983-09-14
SU1299515A3 (ru) 1987-03-23
SE8404006L (sv) 1985-02-13
IL72621A0 (en) 1984-11-30
SE8404006D0 (sv) 1984-08-07
AT387025B (de) 1988-11-25
GB2144748B (en) 1987-03-04
FI843112A (fi) 1985-02-13

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